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19,906 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Ocular toxoplasmosis in Latin American and European patients: clinical characteristics, visual outcomes, and recurrence patterns.

Shamani-Aminian A, Adán A, Llorenç V · 2026 · Journal of ophthalmic inflammation and infection

Ocular toxoplasmosis is the most common cause of posterior uveitis worldwide and a major cause of visual impairment. Previous studies suggest that the disease may follow a more aggressive clinical course in patients from Latin America;…

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Negative / Null Result ReportMedicine

Thoracic radiographs in dogs with gastric dilatation-volvulus rarely affect the decision to proceed with surgery or survival to discharge: a 25-year retrospective study of 176 cases.

Lee J, DeGroot W · 2026 · Journal of the American Veterinary Medical Association

Objective To assess whether thoracic radiographs in dogs with gastric dilatation-volvulus (GDV) are associated with the decision to proceed with surgery and survival to discharge. Methods A retrospective cohort study of dogs with GDV…

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Negative / Null Result ReportMedicine

When coverage is high: rethinking the role of caregiver perceptions in childhood vaccination uptake in Uganda.

Gunderson AK, Kwon T, Kumarasinghe Y et al. · 2026 · Transactions of the Royal Society of Tropical Medicine and Hygiene

Background Beliefs of a child's primary caregiver are known to influence immunization uptake. As coverage increases, the characteristics of households with undervaccinated children may be shifting. Methods We conducted a cross-sectional…

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Negative / Null Result ReportMedicine

ESR1 as a candidate gene for adolescent idiopathic scoliosis pathogenesis in North-West Indian population.

Kowra S, Singh H, Singh V et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Introduction Estrogens are crucial in the development and growth of skeletal systems. Estrogen receptor alpha (ESRα) and beta (ESRβ) are crucial regulators of estrogen response. Estrogen receptor genes (ESR1 and ESR2) have been extensively…

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Negative / Null Result ReportMedicine

Effect of Concurrent Anti-Seizure Medications on the Efficacy of the Ketogenic Diet in Children with Epilepsy.

Sharma S, Aschner A, Kabir N et al. · 2026 · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

Rationale The ketogenic diet (KD) is a well-established therapeutic option for children with non-surgical drug-resistant epilepsy (DRE). The purpose of this study was to determine whether specific anti-seizure medications (ASM) are…

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Negative / Null Result ReportMedicine

Clinical Outcomes in Japanese Patients with Chronic Limb Threatening Ischaemia Undergoing Tibial and Pedal Bypass with a Single Segment Great Saphenous Vein Graft.

Kobayashi T, Takahara M, Kikuchi S et al. · 2026 · European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

Objective A single segment great saphenous vein (GSV) with a diameter ≥ 3.0 mm is widely accepted as the standard conduit for tibial and pedal bypass in chronic limb threatening ischaemia (CLTI) based on studies in European and American…

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Negative / Null Result ReportMedicine

Perinatal and Lifestyle Factors Associated with Childhood Alanine Aminotransferase Levels as an Early Indicator of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Population-Based Study.

de Ruyter H, Aitokari L, Iqbal A et al. · 2026 · The Journal of pediatrics

Objective To investigate associations of perinatal and lifestyle factors with alanine aminotransferase (ALT) levels as an early indicator of metabolic dysfunction-associated steatotic liver disease (MASLD). Study design Data from the…

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Negative / Null Result ReportMedicine

Systemic inflammatory indices as predictors of adverse outcomes in pregnancies with vascular events: A retrospective cohort study.

Toptas GR, Firatligil FB, Ozdal BB et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Objective To investigate the association between systemic inflammatory indices, including the systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and aggregate index of systemic inflammation (AISI), and…

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Negative / Null Result ReportMedicine

Assessing the essential parameters of race, ethnicity and geography in endometrial cancer and the impact on presentation, treatment and outcomes.

Jamieson A, Kwon J, Gao T et al. · 2026 · Gynecologic oncology

Background Race, ethnicity, and geography can impact cancer management, genomics and outcomes. We aimed to determine the ethnic and geographic diversity of endometrial carcinoma (EC) patients in our province and their impact on molecular…

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Negative / Null Result ReportMedicine

Identification of chrono-nutrition behavior patterns and their associations with sociodemographic characteristics, diet quality, and obesity.

Murakami K, Shinozaki N, Livingstone MBE et al. · 2026 · The British journal of nutrition

While chrono-nutrition behaviors are inter-related, few studies examined patterns of chrono-nutrition behaviors using a comprehensive set of these behaviors. This study aimed to identify chrono-nutrition behavior patterns and examine their…

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Negative / Null Result ReportMedicine

Relationships between rest-activity rhythms, cancer-related fatigue, and quality of life: Results from a time-restricted eating randomized controlled trial.

Kleckner AS, Zhou Y, Diaz-Mercado Y et al. · 2026 · Chronobiology international

Circadian rest-activity rhythms, or a person's consistency in their daily activity and rest patterns, can be quantified using various parametric and non-parametric methods. However, these methods are seldom applied to understand symptoms…

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Negative / Null Result ReportMedicine

IL-6 and TNFα are associated with depressive symptoms among men in a community-based cohort, with a tentative trend for IL-17A: Findings from the Shika Study in Japan.

Tsuboi H, Sakakibara H, Minamida-Urata Y et al. · 2026 · Neuro endocrinology letters

Objective Emerging evidence suggests that low-grade systemic inflammation contributes to depressive symptoms; however, population-based longitudinal evidence, particularly from community samples, remains limited. This study examined the…

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