Inhibition of MLLT1 Limits Growth of KMT2A::AFF1 Leukemias Without Killing Healthy Hematopoietic Stem Cells.
Rajhansa S; Crump NT; Khoo HM; Dopico-Fernandez A; Bozhilov Y; Brennan PE; Fedorov O; Adams C · 2026 · Experimental hematology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
A major challenge in cancer therapeutics has been the identification of targets that are selectively toxic to cancer cells while displaying limited effects on healthy counterparts. Toxicities related to blood production from hematopoietic…
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Metadata source: Europe PMC · DOI 10.1016/j.exphem.2026.105458