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Browse the failure-mode index

19,871 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

A combined Ames and in vivo genotoxicity assessment of dimyricetin-yl-diselenide, a structurally defined organoselenium flavonoid.

Zhang L, Liu X, Zhang C et al. · 2026 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Dimyricetin-yl-diselenide (DMS; 3,5,7-trihydroxy-8-[[3,5,7-trihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)chromen-8-yl]diselanyl]-2-(3,4,5-trihydroxyphenyl)chromen-4-one) is a structurally defined organoselenium flavonoid dimer in which two…

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Negative / Null Result ReportMedicine

Adding Self-directed Psychological Support to Usual Rehabilitation Following Anterior Cruciate Ligament Reconstruction Did Not Increase Return-to-Sport Rates at 12 Months. Results From the BAck iN the Game (BANG) Randomized Controlled Trial.

Fältström A, Hedevik H, Ardern CL et al. · 2026 · The Journal of orthopaedic and sports physical therapy

OBJECTIVE: To evaluate the efficacy of internet-delivered psychological support-the BAck iN the Game (BANG) intervention-after anterior cruciate ligament reconstruction (ACLR) for improving return to sport (RTS). DESIGN: Randomized…

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Negative / Null Result ReportMedicine

Increasing meniscal repair rates during ACL reconstruction did not increase reoperation risk: An analysis of surgical trends from 2015 to 2023.

Kekki C, Essen CV, Cristiani R et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

Purpose To evaluate surgical trends over time in meniscal procedures during anterior cruciate ligament reconstruction (ACLR) and compare meniscal reoperation rates and subjective outcomes between 2015-2019 and 2020-2023. Methods This study…

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Negative / Null Result ReportMedicine

A pilot study of a sexual health workshop for oncology staff: feasibility, impact, and gaps in addressing young adult breast cancer survivorship needs.

Rick TJ, Girard A, Topalian A et al. · 2026 · Journal of cancer survivorship : research and practice

Purpose Sexual health concerns are highly prevalent and distressing among adolescent and young adult (AYA) breast cancer survivors, yet are rarely addressed in routine oncology care. Lack of provider training remains a key barrier to…

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Negative / Null Result ReportMedicine

Exploring unconventional antimicrobial stewardship models: options beyond traditional prospective audit and feedback.

Christensen AB, Cochran GL, Avedissian SN et al. · 2026 · Infection control and hospital epidemiology

Background Prospective audit and feedback (PAF) is a core antimicrobial stewardship strategy. Discontinuing PAF in favor of alternative interventions has not been previously evaluated. Methods This descriptive study assessed changes in…

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Negative / Null Result ReportMedicine

Donning gloves before patient contact, with or without prior hand hygiene.

Bayhan GI, Aydın Altuntaş C, Cevahir N · 2026 · Journal of infection in developing countries

Objective Hand hygiene (HH) is a fundamental infection prevention measure in healthcare settings, playing a crucial role in reducing healthcare-associated infections (HAIs). Despite its importance, HH compliance remains suboptimal…

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Negative / Null Result ReportMedicine

Differential Expression of Dopamine-Related Genes Across Developmental and Parental Stages in the Burying Beetles, Nicrophorus orbicollis.

Panaitof SC, Kermagi MM · 2026 · Archives of insect biochemistry and physiology

Dopamine has diverse roles in the regulation of reproduction and social behaviors in insects. In the burying beetle, Nicrophorus orbicollis, a species with extended care, our previous work has shown that brain dopamine levels increase…

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Negative / Null Result Report

Community-level Monitoring of Antimicrobial Resistance following Mass Administration of Azithromycin to Reduce Child Mortality in Côte d’Ivoire: Results from Two Rounds of Surveillance

Dulli L, Gbonon V, Touré F et al. · 2026 · Preprint

Background Mass Drug Administration (MDA) of azithromycin for the elimination of trachoma and, more recently, for the reduction of child mortality, are public health strategies shown, with mixed results, to contribute to the development of…

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Negative / Null Result ReportMedicine

Heat treatment combined with hybrid exercises retraining mitigates cellular markers of protein turnover after hindlimb suspension in male mice: A pilot study.

Normand-Gravier T, Solsona R, Bertrand-Gaday C et al. · 2026 · Experimental physiology

Recent evidence suggests that heat treatment (HT) and resistance training can limit skeletal muscle mass loss during immobilization. However, the effects of repeated HT sessions combined with hybrid exercises (EX), which promote both…

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