Longitudinal course of neurofilament light chain levels in amyotrophic lateral sclerosis-insights from a completed randomized controlled trial with rasagiline.
Witzel S; Statland JM; Steinacker P; Otto M; Dorst J; Schuster J; Barohn RJ; Ludolph AC · 2024 · European journal of neurology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background and purpose Rasagiline might be disease modifying in patients with amyotrophic lateral sclerosis (ALS). The aim was to evaluate the effect of rasagiline 2 mg/day on neurofilament light chain (NfL), a prognostic biomarker in ALS.…
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Metadata source: Europe PMC · DOI 10.1111/ene.16154