Negative / Null Result ReportOpen accessGynecology and obstetrics
Jingting Liu, Yijun Dong, Yawei Zhou et al. · 2024 · BMC Pregnancy and Childbirth
Abstract Background Observational epidemiological studies suggested that immunological dysregulation and inflammation play a significant role in the placental and renal dysfunction that leads to maternal hypertension. The immunophenotypes' possible causalities with hypertensive disease of pregnancy remain ambiguous. We performed two-sample Mendelian randomization (MR) analyses to comprehensively investigate the causal effect of immunophenotypes on hypertensive disorder of pregnancy (HDP). Methods The large-scale genome-wide association studies (GWASs) data on immunological traits was taken fro
View details →Negative / Null Result ReportOpen accessMedicine (General)
Emily Sheppard, MScPT, Michael Smyth, MSc, Todd Dow, BSc et al. · 2020 · Archives of Rehabilitation Research and Clinical Translation
Objective: To assess the effect the Pre-clerkship Residency Exploration Program (PREP) had on student career interest and improving understanding of physical medicine and rehabilitation (PMR). Design: During a 2-week program, students were exposed to a PMR elective, workshop, career presentation, and panel discussion with PMR residents. Interest and understanding were assessed using pre- and postprogram questionnaires. Setting: PREP was held at a Canadian medical school during the summer between the second and third years of undergraduate medical training. Participants: Second-year medical stu
View details →Negative / Null Result ReportOpen accessEducation (General)
Wonseok Chang, Yura Kim, Hye Jin Park · 2024 · Korean Journal of Medical Education
Purpose Although interest in various forms of learning media is increasing due to the coronavirus disease 2019 (COVID-19) pandemic there is relatively little research on influencing student motivation by intervening in cognitive processing. The purpose of this study was to present the optimal form of learning materials provided to medical students. Methods This study provided learning materials in class at a level according to social cues (script, video [artificial intelligence (AI) voice], video [professor voice]) based on the principle of voices among the principles of personalization, voice
View details →Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Dan Liang, Chang Liu, Xingyu Zhang · 2026 · Food, Nutrition and Health
Abstract Background This study aimed to investigate the relationship between dietary iron intake and risk of abdominal aortic calcification (AAC) in middle-aged and older US adults. Methods We analyzed data from the 2013-2014 National Health and Nutrition Examination Survey (NHANES). Multivariate linear and logistic regression models were employed to evaluate the association between dietary iron intake and AAC score, as well as the likelihood of both AAC and severe AAC. To investigate potential non-linear dose-response relationships, we performed restricted cubic spline (RCS) modeling. In addi
View details →Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Yinuo Li, Xi Liu, Qian Hong et al. · 2024 · Frontiers in Cardiovascular Medicine
BackgroundRecent epidemiological studies have indicated a correlation between platelet indices and pulmonary arterial hypertension (PAH), yet the causality between them remains unclear. To explore the causal relationship between four platelet indices and PAH, with the aim of providing a theoretical basis for clinical prevention and treatment.MethodsSingle-nucleotide polymorphisms (SNPs) associated with platelet-related traits were selected as exposure factors from published genome-wide association studies (GWAS), including: platelet count (PLT), plateletcrit (PCT), mean platelet volume (MPV),
View details →Negative / Null Result ReportOpen accessMedicine
Bohan Jia, Junyi Sun, Di Zhu et al. · 2025 · Scientific Reports
Abstract Cancer significantly contributes to the unfavorable prognosis of coronavirus disease 2019 (COVID-19) patients. The efficacy and safety of azvudine and nirmatrelvir/ritonavir (Paxlovid) in cancer patients with COVID-19 remain uncertain. Therefore, we designed a comprehensive retrospective study encompassing clinical data of 32,864 hospitalized COVID-19 patients, 691 of whom were cancer patients treated with azvudine and 200 were cancer patients treated with Paxlovid. After 2:1 propensity score matching, 397 patients in the azvudine group and 199 patients in the Paxlovid group were enro
View details →Negative / Null Result ReportOpen accessDentistry
Disha Kumar, Anant Gopal Nigam, Nikhil Marwah et al. · 2018 · Journal of Indian Society of Pedodontics and Preventive Dentistry
Background and Objectives: The aim of this study was to examine the arch dimensions of beta thalassemia major patients in comparison with normal individuals. Materials and Methods: Dental arch dimensions were compared between thalassemic patients and normal individuals in the age group of 12–16 years in the maxillary and mandibular arch corresponding to each other regarding age, sex and Angle's molar relationship. A total number of sixty cases in each group were taken. Maxillary and mandibular impressions were made with alginate for all the sixty participants in each group and poured with die
View details →Negative / Null Result ReportOpen accessMedicine (General)
M.A. Arbex, L.C. Martins, L.A.A. Pereira et al. · 2007 · Brazilian Journal of Medical and Biological Research
Studies of cooking-generated NO2 effects are rare in occupational epidemiology. In the present study, we evaluated the lung function of professional cooks exposed to NO2 in hospital kitchens. We performed spirometry in 37 cooks working in four hospital kitchens and estimated the predicted FVC, FEV1 and FEF25-75, based on age, sex, race, weight, and height, according to Knudson standards. NO2 measurements were obtained for 4 consecutive days during 4 different periods at 20-day intervals in each kitchen. Measurements were performed inside and outside the kitchens, simultaneously using Palm diff
View details →Negative / Null Result ReportOpen accessOphthalmology
Ahmed S Abdel-Wanes, Abelrahman G Salman, Azza M.A Said et al. · 2020 · Journal of the Egyptian Ophthalmological Society
Aim To determine the risk factors responsible for opaque bubble layer (OBL) formation in femtosecond-laser-assisted in situ keratomileusis (FSL-LASIK). Patients and methods A retrospective, comparative study was carried out from January 2015 to January 2017 in El-Watany Eye Hospital. Two hundred eyes who were eligible for FSL-laser-assisted in situ keratomileusis (FSL was done using FS200, wavelight, Germany SR/1025-1-380) were classified into two groups. Group I: the study group with OBL formation during surgery (100 eye) and group (II): the control group without OBL formation during surgery
View details →Negative / Null Result ReportOpen accessMedicine
Zagorac Slaviša, Bumbaširević Marko, Lešić Aleksandar et al. · 2008 · Srpski Arhiv za Celokupno Lekarstvo
Introduction Multiple trauma is one of the leading causes of mortality and morbidity in the population of people under 45 years of age. The consequences of multiple trauma have huge epidemiological, social and economic significance. Objective The aim of the paper was to analyze the conclusive treatment outcome of multiply traumatized patients with respect to their sex, age, injury mechanism and type. METHOD This retrospective study included 100 patients with multiple injuries (ISS>16) treated in the Emergency Room of the Clinical Centre of Serbia in the course of 2004. Clinical, X-ray, laborat
View details →Negative / Null Result ReportOpen accessMedicine
Levent Cigerim, Erkan Feslihan · 2019 · Journal of Oral Health and Oral Epidemiology
BACKGROUND AND AIM: Alterations in blood pressure (BP) and variability of heart rate (HR) throughout dental procedures were not clearly understood. The aim of this study is to evaluate the effects of body mass index (BMI) on BP and HR in patients undergoing tooth extraction. METHODS: Based on BMI, 831 patients who underwent single tooth extraction were divided into two groups; group 1: underweight and normal-weight patients, group 2: overweight and obese patients. BP and HR were monitored before local anesthesia and after tooth extraction. For statistical analysis of the data, Number Cruncher
View details →Negative / Null Result ReportOpen accessSports medicine
Tim Wang MD, Van Krueger, Roslyn Kackman et al. · 2025 · Orthopaedic Journal of Sports Medicine
Objectives: Osteochondral allograft (OCA) transplantation is an effective treatment method for articular cartilage damage in the knee. The mid- and long-term outcomes of patellofemoral OCA transplantation has been less frequently reported compared to those of the medial and lateral compartments of the knee, and these grafts often show lower survival rates and worse patient-reported outcomes. The unique morphology and biomechanics of the patellofemoral compartment leads to different pathologies than other areas of the knee. The purpose of this study was to assess graft survivorship and patient-
View details →Negative / Null Result ReportOpen accessAnesthesiology
Marzieh khalaji, Mohadese Babaie, Fatemeh Bayat et al. · 2025 · BMC Anesthesiology
Abstract Aim This study aims at comparing the impact of Magnesium Sulfate and Lidocaine sprays on hemodynamic changes after laryngoscopy and tracheal intubation. Design This double-blind clinical trial (code IRCT20230719058846N1) was conducted on the patients undergoing elective surgery in the city of Karaj. Methods A total of 100 patients, aged 18 to 40 years and classified as ASA I or II, who were candidates for elective surgery, were randomly assigned to two equal groups. Prior to intubation, patients received lidocaine spray (5 puffs of Lidocaine 10%) in one group, and magnesium sulfate sp
View details →Negative / Null Result ReportOpen accessDentistry
Polavarapu Venkata Ravi Chandra, Vemisetty Hari Kumar, Surakanti Jayaprada Reddy et al. · 2015 · Dental Research Journal
Background: The aim of this study was to evaluate and compare the in vitro biofilm forming capacity of Enterococcus faecalis on Gutta-percha points disinfected with four disinfectants. Materials and Methods: A total of 50 Gutta-percha points used in this study were divided into four test groups based on disinfectant (5.25% sodium hypochlorite, 2% chlorhexidine gluconate, 20% neem, 13% benzalkonium chloride [BAK]), and one control group. The Gutta-percha points were initially treated with corresponding disinfectants followed by anaerobic incubation in Brain Heart Infusion broth suspended with h
View details →Negative / Null Result ReportOpen accessMedicine (General)
Fatemeh Zanganeh, Amir Jalali, Hamid Galehdari et al. · 2014 · Iranian South Medical Journal
Background: Cytochrome P450 2E1 (CYP2E1) is a main enzyme which plays a major role in activating and detoxifying many xenobiotics, carcinogens and drugs. Available studies suggest that CYP2E1 single nucleotide polymorphisms (SNPs) are involved in the risk of developing certain cancers after exposure to carcinogens. The purpose of the present study was to assess genotype and allele frequencies of polymorphic CYP2E1*5B in the Iranian population. Material and Methods: This study was performed on 200 healthy individuals (female: 100, male: 100) in medical laboratories of Ahvaz during 2011. The CYP
View details →Negative / Null Result ReportOpen accessVeterinary medicine
Sladojević Ž., Kasagić D., Kukolj B. et al. · 2013 · Veterinarski Glasnik
The objective of this work was to investigate the influence of housing conditions, number of farrowing and number of pigs in litter on weight loss in sows during lactation. The experiment included 60 sows, half breed developed by cross breeding of Big Yorkshire and Swedish Landrace in lactation. Body weight of the sows (kg) was determined 2nd, 7th, 14th, 21st and 28th day after farrowing. On the basis of the obtained values, there was calculated the difference in body weight between two consecutive investigation periods. The sows were divided into two groups and held in different housing condi
View details →Negative / Null Result ReportOpen accessHistory of scholarship and learning. The humanities
Asmaa Al-suhimi · 2023 · مجلة جامعة الأنبار للعلوم الإنسانية
The current study aimed to design a counseling program based on gratitude for the development of psychological well-being, verify the effectiveness of this program and identify the continuity of its impact through the results of follow-up measurement after a month of its application. An intentional sample of (24) female students from the College of Education at King Khalid University, were randomly divided into two groups, a control, and an experimental group, each group consisted of 12 students, and the research tools used to measure the psychological well-being of university students Prepare
View details →Negative / Null Result ReportOpen accessArctic medicine. Tropical medicine
Emanuelle Santos de Carvalho Cardoso, Bruna Laís Santos de Jesus, Luciano Gama da Silva Gomes et al. · 2015 · Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Although urine is considered the gold-standard material for the detection of congenital cytomegalovirus (CMV) infection, it can be difficult to obtain in newborns. The aim of this study was to compare the efficiency of detection of congenital CMV infection in saliva and urine samples. METHODS: One thousand newborns were included in the study. Congenital cytomegalovirus deoxyribonucleic acid (DNA) was detected by polymerase chain reaction (PCR). RESULTS: Saliva samples were obtained from all the newborns, whereas urine collection was successful in only 333 cases. There was no stat
View details →Negative / Null Result ReportOpen accessSurgery
Cláudio de Saboya David, Alberto Goldenberg · 2018 · Acta Cirúrgica Brasileira
Abstract Purpose: To evaluate the behavior of arterial circulation and testicular volume in patients submitted to conventional inguinal hernia repair without the use of a synthetic prosthesis to reinforce the posterior wall. Methods: A prospective observational clinical trial was performed on 26 male patients with unilateral inguinal hernia types I and II by the Nyhus classification, who underwent surgical correction using the modified Bassini technique. Bilateral Doppler ultrasonography was performed preoperatively, at the third and at the sixth postoperative month. The studied variables were
View details →Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Somendra Bansal, Ketankumar G Rupala, Prasun Ghosh et al. · 2021 · Indian Journal of Urology
Introduction: The end-stage renal disease (ESRD) population is increasing worldwide and organ shortage is an important issue. The disparity between the availability of organs and waitlisted patients for transplants has forced many transplant centers across the world to use marginal kidney donors. We assess and compare postoperative estimated glomerular filtration rate (eGFR) in patients who received a graft from marginal renal donor (MRD) versus those who received a graft from standard renal donor (SRD). Methods: A total of 214 patients with ESRD underwent open live donor renal allografting fr
View details →Negative / Null Result ReportOpen accessMechanics of engineering. Applied mechanics
Atefeh Karimzadeh, Majid R. Ayatollahi, A.R. Bushroa · Latin American Journal of Solids and Structures
Abstract The purpose of this study was to investigate the effects of shade and material type and shape in dental polymer composites on the hardness and shrinkage stress of bulk and two-layered restoration systems. For this purpose, some bulk and layered specimens from three different shades of dental materials were prepared and light-cured. The experiments were carried out on three types of materials: conventional restorative composite, nanohybrid composite and nanocomposite. Micro-indentation experiment was performed on the bulk and also on each layer of layered restoration specimens using a
View details →Negative / Null Result ReportOpen accessSpecial aspects of education
Houry Debra, Green Steven, Callaham Michael · 2012 · BMC Medical Education
Abstract Background Prior efforts to train medical journal peer reviewers have not improved subsequent review quality, although such interventions were general and brief. We hypothesized that a manuscript-specific and more extended intervention pairing new reviewers with high-quality senior reviewers as mentors would improve subsequent review quality. Methods Over a four-year period we randomly assigned all new reviewers for Annals of Emergency Medicine to receive our standard written informational materials alone, or these materials plus a new mentoring intervention. For this program we paire
View details →Negative / Null Result ReportOpen accessNursing
Maryam Ahmadinezhad, Marzieh Kargar, Fatemeh Vizeshfar et al. · 2017 · Iranian Journal of Nursing and Midwifery Research
Background: Postmenopausal women experience a variety of symptoms, among which sleep disorder is one of the most common problems. Acupressure and Pilates exercise programs are effective nonpharmaceutical treatments which can improve sleep quality. In the present study, we aimed to compare the effects of acupressure and Pilates-based exercises on the sleep quality of postmenopausal women referred to medical clinics. Materials and Methods: In this single-blinded randomized controlled clinical trial, we recruited 108 women aged 40–60 years who were randomly assigned into one control and two inter
View details →Negative / Null Result ReportOpen accessMedicine
Amudha Jayanthi Anand, Mei Chien Chua, Siok Hong Khoo et al. · 2017 · Proceedings of Singapore Healthcare
Introduction: Extended hospitalization of low birth weight infants increases risk of medical and psychosocial complications. Our aim was to reduce the length of hospitalization and assess safety and cost savings of discharging infants at a weight of 1900 g instead of 2000 g, as has been the practice. Methods: This is a single-centre, nurse led quality improvement project done at a tertiary neonatal unit in Singapore with primary outcome of reducing average length of stay in selected low birth weight infants. In phase 1, infants with birth weight between 1000 and 1700 g were discharged at 1900
View details →Negative / Null Result ReportOpen accessMedicine (General)
Mori N, Kobayashi A, Yokogawa H et al. · 2025 · International Medical Case Reports Journal
Natsuko Mori, Akira Kobayashi, Hideaki Yokogawa, Tomomi Higashide Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, JapanCorrespondence: Akira Kobayashi, Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan, Tel +81-76-265-2403, Fax +81-76-222-9660, Email eyekoba@gmail.comPurpose: To describe two corneal adverse events temporally associated with anti–tumor necrosis factor-α (TNF-α) therapy—one with severe fibrovascular pannus and another with epithelial keratopath
View details →Negative / Null Result ReportOpen accessSurgery
Takatsugu Fujii, Shigeo Toda, Yuki Nishihara et al. · 2020 · Surgical Case Reports
Abstract Background Ischemic colitis can occur after colectomy and is sometimes difficult to treat. We report 4 cases of refractory, delayed onset, regional congestive colitis occurring on the anal side of the anastomosis after laparoscopic left hemicolectomy. Case presentation A total of 191 patients underwent surgery for left colon cancer (transverse, descending, and sigmoid colon cancer) at our hospital from January 2012 to December 2017. During the procedures, the left colic artery (LCA) or sigmoid colic artery (SA) was dissected, the superior rectal artery (SRA) was preserved, and the inf
View details →Negative / Null Result ReportOpen accessPsychology
Barrotul Jazilah · 2020
The aim of this research was to explore burnout, work engagement, and job demand among debt collector workers. The total available population of employees (N= 32) Consumer Collection and Remedial Unit Bank Tabungan Negara Cabang Surabaya…
View details →Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Pylväläinen J, Talala K, Murtola T et al. · 2019 · Clinical Epidemiology
Juho Pylväläinen,1–3 Kirsi Talala,4 Teemu Murtola,5–7 Kimmo Taari,8 Jani Raitanen,1,9 Teuvo L Tammela,6 Anssi Auvinen1 1Tampere University, Faculty of Social Sciences (Health Sciences), Tampere, Finland; 2Helsinki University, Faculty of Medicine, Department of Diagnostics and Therapeutics, Helsinki, Finland; 3Helsinki University Central Hospital, Medical Imaging Center, Helsinki, Finland; 4Cancer Society of Finland, Finnish Cancer Registry, Mass Screening Registry, Helsinki, Finland; 5Tampere University, Faculty of Medicine and Health Technology, Prostate Cancer Research
View details →Negative / Null Result ReportOpen accessSports medicine
Phob Ganokroj MD, Bradley W. Fossum BA, Justin Hollenbeck MSc et al. · 2023 · Orthopaedic Journal of Sports Medicine
Background: Segmental medial meniscal allograft transplantation (MAT) has been shown to restore knee biomechanics; however, stable fixation of the transplantation is critical to avoid extrusion and maximize healing. Purpose: To evaluate the degree of meniscal extrusion and biomechanical function of segmental medial MAT performed with meniscocapsular sutures versus repair augmentation with knotless suture anchors. Study Design: Controlled laboratory study. Methods: Segmental midbody medial meniscectomy and subsequent segmental medial MAT were performed on 10 fresh-frozen cadaveric knees. The kn
View details →Negative / Null Result ReportOpen accessDairy processing. Dairy products
Camélia Marchand, Isabelle Royer, Rachel Gervais et al. · 2024 · Journal of Dairy Science
ABSTRACT: Most trace minerals (TM) are fed above dairy cow requirements in commercial herds but their fate and effects on dairy cows have not been well documented. In this study, we evaluated the effects of feeding short-term sulfate TM above recommendations on apparent total-tract digestibility of nutrients, rumen fermentation characteristics, serum concentrations, and milk yield and composition, as well as milk, fecal, and urinary TM excretion in midlactation dairy cows. Eight multiparous Holstein cows with an average body weight (± SD) of 684 ± 29 kg at 82 ± 10 DIM in a quadruple 2 × 2 cros
View details →