e-ISSN: Pending

Browse the failure-mode index

19,820 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen access

有酸素運動 (Aerobics) を中心にした一般教養体育実技の有効性と限界について-第一報:血液組成と体組成におよぼす影響-

田原, 靖昭, 西澤, 昭, 管原, 正志 et al. · 1991

Aerobic exercise class was opened and blood and physical composition were examined. Results indicated that no significant improvement on measured items was observed. Frequency of participation is suggested to be increased or class goal…

View details →
Negative / Null Result ReportOpen access

Performance of Perforated Heat Exchanger Surfaces

J. R. Mondt, D. C. Siegla · 1974

Heat transfer and flow friction behavior have been measured for plain and perforated plate-fin and 10-deg herringbone surfaces. For the range of geometries and Reynolds numbers studied, the perforations produced no significant improvement…

View details →
Negative / Null Result ReportOpen access

Treatment outcomes of different prognostic groups of patients on cancer and leukemia group B trial 39801: induction chemotherapy followed by chemoradiotherapy compared with chemoradiotherapy alone for unresectable stage III non-small cell lung cancer

Akerley, Wallace, Herndon, James E. 2nd, Vokes, Everett E. et al. · 2017

BACKGROUND: In Cancer and Leukemia Group B 39801, we evaluated whether induction chemotherapy before concurrent chemoradiotherapy would result in improved survival and demonstrated no significant benefit from the addition of induction…

View details →
Negative / Null Result ReportOpen access

Treatment Outcomes of Different Prognostic Groups of Patients on Cancer and Leukemia Group B Trial 39801: Induction Chemotherapy Followed by Chemoradiotherapy Compared with Chemoradiotherapy Alone for Unresectable Stage III Non-small Cell Lung Cancer

Akerley, Wallace, Vokes, Everett E., Cicchetti, M Giulia et al. · 2009

BackgroundIn Cancer and Leukemia Group B 39801, we evaluated whether induction chemotherapy before concurrent chemoradiotherapy would result in improved survival and demonstrated no significant benefit from the addition of induction…

View details →
Negative / Null Result ReportOpen access

IL-24 regulated CXCR4 at post-transcriptional level.

Jiankang Jin (703171), Stephen J. Archibald (703175), Janani Panneerselvam (703170) et al. · 2015

A , RT-PCR analysis showed IL-24 reduced CXCR4 mRNA levels at 6 h and 24 h ( P B , CXCR4 promoter activity was determined using a luciferase reporter vector. Induction of IL-24 showed no significant reduction in luciferase activity…

View details →
Negative / Null Result ReportOpen access

Effects of α-MSH treatment on Caspase 3 activity.

Andrew W. Taylor (451751) · 2013

The macrophages lysates were assayed for protein concentration and Caspase 3 activity. There was no significant change of Caspase 3 activity in cells treated with α-MSH compared to SFM cells. The graft is the mean ± SD of Caspase 3…

View details →
Negative / Null Result ReportOpen access

Conflict duration on the flanker task (i.e., reaction time for each incongruent trial–reaction time for each congruent trial) pre- (white bar) and post-treatment (black bar) with OT or placebo.

Yuko Yoshimura (283970), Hirotoshi Hiraishi (283977), Mitsuru Kikuchi (140272) et al. · 2015

Two-way ANOVA (treatment × drug) failed to demonstrate any drug or treatment effects, and no significant interaction between these two factors was detected. Therefore, we failed to demonstrate any OT-related effect on…

View details →
Negative / Null Result ReportOpen access

Cutaneous sterile pyogranuloma/granuloma syndrome in a dog

SPATERNA, Andrea, MECHELLI A., SANTORO D. et al. · 2008

A case of canine cutaneous sterile pyogranuloma/granuloma syndrome (SPGS) with generalized asymmetrical alopecia and plaques is described. Results from histopathologic examination were suggestive of SPGS and failed to demonstrate any…

View details →
Negative / Null Result ReportOpen access

Visual impairment, aging and driving ability

Wood, Joanne M. · 2002

It has been suggested that over 90% of the sensory information for driving is visual. Despite this belief, traditional studies have failed to demonstrate that increased crash rates arise from impaired vision. However, more recent studies…

View details →
Negative / Null Result ReportOpen access

The MINERVA study design and rationale: A controlled randomized trial to assess the clinical benefit of minimizing ventricular pacing in pacemaker patients with atrial tachyarrhythmias

Manolis AS, Padeletti L., Mont L et al. · 2008

Dual-chamber (DDD) pacing has generally been regarded as "physiologic pacing" and therefore expected to be superior to ventricular pacing. Major randomized trials have so far failed to demonstrate significant reductions in the incidences…

View details →
Negative / Null Result ReportOpen access

Transient Crossed Aphasia: A Case Study with SPECT

José M. Ferro, Guilhermina Cantinho, Élia Baeta · 1991

A 45-year-old right-handed man developed “crossed” anomie aphasia, neglect and inaccurate reaching of his left arm in both hemispaces due to a right parietal haemorrhage. Aphasia cleared in a few days. SPECT failed to demonstrate crossed…

View details →
Negative / Null Result ReportOpen access

Subscriptions: Information about subscribing to Stroke is online at at UNIV OF EDINBURGH on Comments, Opinions, and Reviews Good Laboratory Practice Preventing Introduction of Bias at the Bench

Marc Fisher, Ulrich Dirnagl, Geoffrey A Donnan et al. · 2020

Background and Purpose-As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human stroke. Summary of Review-Accumulating…

View details →
Negative / Null Result ReportOpen access

Feasibility of progesterone treatment for ischaemic stroke

Claire L. Gibson (6162488), Philip M. Bath (3111867) · 2015

Two multi-centre phase III clinical trials examining the protective potential of progesterone following traumatic brain injury have recently failed to demonstrate any improvement in outcome. Thus, it is timely to consider how this impacts…

View details →
Negative / Null Result ReportOpen access

Influence of Job Familiarity on Job Evaluation Ratings

Kaupins, Gundars · 1990

The effect of job familiarity on job evaluation ratings was investigated. Data came from a survey of 222 personnel specialists and middle to upper level managers. The results failed to show significant associations between various measures…

View details →
Negative / Null Result ReportOpen access

Patent foramen ovale : story closed?

Schellinger, Peter Dieter, Steiner, Thorsten, Köhrmann, Martin et al. · 2019

The optimal treatment strategy for secondary prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) has been a matter of controversy for decades. After three randomized trials failed to show a benefit of closure with…

View details →