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Negative / Null Result Report· cited by 1

The dependence of the amino acid backbone conformation on the translated synonymous codon is not statistically significant

Javier González-Delgado; Pablo Mier; Pau Bernadó; Pierre Neuvial; Juan Cortés · 2025 · Proceedings of the National Academy of Sciences

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

The correlation between synonymous codon usage and secondary structure in translated proteins has been widely demonstrated. This usage plays a capital role in tuning translational rates and protein folding kinetics, indirectly influencing…

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Metadata source: Crossref · DOI 10.1073/pnas.2503264122