19,820 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Rezaeinejad, Sepidarkish, Moini et al. · 2026 · Pregnancy hypertension
While cigarette smoking has been paradoxically associated with a reduced risk of preeclampsia, the effect of waterpipe (WP) smoking, an increasingly prevalent form of tobacco use remains poorly understood. This study aimed to investigate…
View details →Ehne, Kastensson, Wedin et al. · 2026 · Journal of bone oncology
The use of postoperative radiotherapy (PORT) as an adjunct to orthopaedic surgery of the long bones is widely recommended. Evidence of the benefits is however sparse. The primary research question of this study was whether PORT reduces the…
View details →Karunayawong, Sukmanee, Butchon et al. · 2026 · BMJ open
Since 1985, the international healthcare community has recommended the ideal rate of caesarean section (CS) to be 10%-15% at the national level. The literature has reported that overused CS without necessary medical indications can be…
View details →Rodrigues, Macedo, de Paulo et al. · 2026 · Oral surgery, oral medicine, oral pathology and oral radiology
To evaluate the effects of sticky bone a biomaterial composed of Solid-PRF (S-PRF), a variant of platelet-rich fibrin (PRF), and deproteinized bovine bone-on bone formation after tooth extraction performed prior to radiotherapy, with…
View details →Olivieri, Amatori, Battocchio et al. · 2026 · Nanomaterials (Basel, Switzerland)
Gold nanorods (AuNRs) were synthesized and optimized with the aim of obtaining strongly hydrophilic nanomaterials, suitable as a drug delivery system (DDS) for copper-based drugs. After careful purification, AuNRs were characterized by…
View details →Bregen, de Buhr, Strutzberg-Minder et al. · 2026 · Veterinary sciences
The reasons for disease outbreaks caused by Actinobacillus pleuropneumoniae (APP) in vaccinated pigs are often unknown and remain a challenge for farmers and veterinarians. One hypothesis for APP vaccine failure is the timing of APP…
View details →Wang, Ouyang, Chen et al. · 2026 · Scientific reports
This study aims to explore the impact of wearing Defocus Incorporated Multiple Segments (DIMS) spectacle lenses on astigmatism in myopic children. This study included 396 myopic children and divided the participants into two groups:the…
View details →Ma, Qiu, Liu · 2025 · Frontiers in nutrition
Acute-on-chronic liver failure (ACLF) patients face high risks of nutritional risk and clinical complications, but whether adjuvant nutritional support reduces adverse complications remains unclear. This study included 6,097 hospitalized…
View details →Kır · 2026 · PeerJ
This research compares the yield and quality of barley ( Hordeum vulgare ), rye ( Secale cereale ), triticale (× Triticosecale Wittmack ), and wheat ( Triticum aestivum ) grown in dry conditions in winter and widely used in producing…
View details →Cheng, Wang, Liu et al. · 2026 · PloS one
There has been ongoing debate over whether people are intuitively honest or intuitively dishonest. A recent social harm account was proposed to address this debate: dishonesty is intuitive when cheating inflicts harm on an abstract other…
View details →Li, Wang, Shen et al. · 2026 · International journal of cancer
Gastric carcinoma (GC) with neuroendocrine differentiation (GCNED) is a rare and particular pathological subtype. The survival outcomes and prognosis of patients with GCNED are currently unclear. We conducted a retrospective cohort study…
View details →Pires Marafon, Reuter, Isola et al. · 2026 · Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
The legal shelf life of platelet concentrates (PCs) has been extended from 5 to 7 days in France since 2018. Our study aimed to determine whether this increase in PC storage time has produced a significant impact on…
View details →Akkaya, Kosar · 2026 · Journal of endodontics
To investigate the influence of different types of intracanal medicaments and root canal sealers on root dentine fracture resistance at different time intervals. A total of 180 single-rooted human mandibular premolars were used. Samples…
View details →Liu, Zhang, Yuan et al. · 2026 · Chemical science
Hexafluoropropylene oxide-dimer acid (HFPO-DA) is widely used in food packaging bags, surfactants, lubricants, etc. As a new substitute for the persistent organic pollutant perfluorooctanoic acid (PFOA), it has been proven to have…
View details →Jiaxing Xin, Ying Cui, Jun Yang et al. · 2025 · IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The intensification of the urban heat island (UHI) effect poses a serious threat to public health, particularly in cities. Effectively mitigating UHI has been a focus of national and international academic research over the last decades. However, most contemporary research has focused on land use mitigation measures within urban areas, with less emphasis on suburban land use. To address this research gap and explore spatial characteristics, we analyzed the driving mechanism of suburban land use patterns on UHI intensity (UHII) within the main urban area of Shenyang City based on high spatial r
View details →Bilan Yang, Xiaoli Xi, Hongsheng Yu et al. · 2024 · Cancer Reports
Abstract Background The optimal treatment strategy for early‐stage hepatocellular carcinoma (HCC) remains controversial, specifically in regard to surgical resection (SR) and ablation. The aim of this study was to investigate the impact of SR and ablation on recurrence and prognosis in early‐stage HCC patients, to optimize treatment strategies and improve long‐term survival. Methods A retrospective analysis was conducted on 801 patients diagnosed with Barcelona Clinic Liver Cancer (BCLC) stage 0/A HCC and treated with SR or ablation between January 2015 and December 2019. The effectiveness and
View details →Wade J. Chalker, Anthony J. Shield, David A. Opar et al. · 2018 · PeerJ
Background Hamstring strain injuries (HSI) are one of the most prevalent and serious injuries affecting athletes, particularly those in team ball sports or track and field. Recent evidence demonstrates that eccentric knee flexor weakness and between limb asymmetries are possible risk factors for HSIs. While eccentric hamstring resistance training, e.g. the Nordic hamstring exercise (NHE) significantly increases eccentric hamstring strength and reduces HSI risk, little research has examined whether between limb asymmetries can be reduced with training. As augmented feedback (AF) can produce sig
View details →Wei-Kai Chuang, Skye Hung-Chun Cheng, Chen-Fang Hung et al. · 2022 · Journal of the Formosan Medical Association
Background/purpose: This study aimed to analyze the long-term outcomes of hypofractionated whole-breast irradiation (WBI) (HF-WBI) compared with those of conventionally fractionated WBI (CF-WBI) for early breast cancer treated with breast-conservation surgery (BCS) and adjuvant WBI in Taiwan. Methods: This study included patients treated at our institution between 2012 and 2016. All patients with early breast cancer received BCS (pT1–2, pN0, M0) and adjuvant WBI through one of two treatment schemes. Propensity score matching analysis was conducted to create comparable cohorts. The major result
View details →Hao WANG, Zhitao GU, Jianyong DING et al. · 2016 · Chinese Journal of Lung Cancer
Background and objective Video-assisted thoracoscopic surgery (VATS) theoretically offers advantages over open thymectomy for clinically early-stage (Masaoka-Koga stage I and II) thymic malignancies. However, longterm outcomes have not been well studied. We compared the postoperative outcomes and survival from a cohort study based on the database of the Chinese Alliance for Research in Thymomas (ChART). Methods Between 1994 and 2012, data of 1,117 patients having surgery for clinically early-stage (Masaoka-Koga stage I and II) tumors were enrolled for the study. Among them, 241 cases underwent
View details →Flávio Kapczinski, Jair Mari, Luiz Henrique Junqueira Dieckmann et al. · 2024 · BMJ Open
Objective This study aims to conduct an overview on the comparative efficacy of valproate in acute mania, bipolar depression and maintenance treatment of bipolar disorder (BD).Method We performed an overview of systematic reviews with meta-analyses of randomised controlled trials (RCTs), registered in PROSPERO (CRD42024497749). We searched Medline and Cochrane Database of Systematic Reviews. Summary measures comparing valproate with placebo or other active drugs were described.Results We included 26 systematic reviews. For acute mania (31 RCTs, n=4376), valproate showed a significantly better
View details →Philip El-Duah, Benjamin Meyer, Augustina Sylverken et al. · 2019 · Viruses
Known human coronaviruses are believed to have originated in animals and made use of intermediate hosts for transmission to humans. The intermediate hosts of most of the human coronaviruses are known, but not for HCoV-NL63. This study aims to assess the possible role of some major domestic livestock species as intermediate hosts of HCoV-NL63. We developed a testing algorithm for high throughput screening of livestock sera with ELISA and confirmation with recombinant immunofluorescence assay testing for antibodies against HCoV-NL63 in livestock. Optimization of the ELISA showed a capability of
View details →M. Behdarnejad, H. Piri, M. Delbari · 2023 · مجله آب و خاک
Introduction In sustainable farming systems, the use of organic fertilizers is of particular importance in increasing crop production and maintaining sustainable soil fertility. Nowadays, the consumption of organic foods is introduced to consumers as an alternative. The result of the application of chemical products is the crisis of environmental pollution, soil and water resources, and the health risk to human society. Nowadays, in order to reduce the effects of misuse of chemical inputs, chemical fertilizers can be replaced with organic biological fertilizers, including animal manure, compos
View details →Zhao Jiandong, Yuan Yongyi, Chen Jing et al. · 2012 · Journal of Translational Medicine
Abstract Background Many patients with enlarged vestibular aqueduct (EVA) have either only one allelic mutant of the SLC26A4 gene or lack any detectable mutation. In this study, multiplex ligation-dependent probe amplification (MLPA) was used to screen for copy number variations (CNVs) of SLC26A4 and to reveal the pathogenic mechanisms of non-syndromic EVA (NSEVA). Methods Between January 2003 and March 2010, 923 Chinese patients (481 males, 442 females) with NSEVA were recruited. Among these, 68 patients (7.4%) were found to carry only one mutant allele of SLC26A4 and 39 patients (4.2%) lacke
View details →Takumi Osawa, Hitoshi Mori, Akane Kawai et al. · 2022 · Journal of Arrhythmia
Abstract Background Uninterrupted dabigatran during atrial fibrillation (AF) ablation is now established as the standard therapy. However, there are few reports on the effects of uninterrupted dabigatran on the intensity of anticoagulation during AF ablation. Methods We retrospectively analyzed 247 consecutive patients who underwent AF ablation in our hospital from January 2017 to December 2018. Patients who took warfarin or uninterrupted direct oral anticoagulants (DOACs) except for dabigatran were excluded. 89 patients underwent ablation with uninterrupted dabigatran (uninterrupted group, ma
View details →Hamed Kalhor, Mamak Adel, Maryam Tofangchiha et al. · 2026 · Annali di Stomatologia
Objectives: This study aimed to assess the effect of a metal artifact removal (MAR) algorithm on the visibility of the second mesiobuccal canal (MB2) of maxillary molars on cone-beam computed tomography (CBCT) scans. Materials and Methods: This cross-sectional study evaluated 41 CBCT scans of patients retrieved from the radiology clinic’s archives. The CBCT scans were saved with and without the MAR algorithm applied. The images were coded and evaluated by two endodontists to assess MB2 detection in maxillary molars and its visibility level using a 5-point Likert scale. Of the 164 samples, 32 w
View details →LI Wen-hong, WANG Jin-wen, CHEN Hao et al. · 2015 · Linchuang shenzangbing zazhi
Objective To study the clinical curative effectiveness of high frequency ultrafiltration for the renal edema with diuretic resistance.Methods We selected 42 cases of nephrotic syndrome with severe edema.Among them,there were 20 cases of diabetic kidney disease,10 cases of lupus nephritis,8 cases of refractory primary nephrotic syndrome,and 4 cases of multiple myeloma nephropathy.All patients were subjected to standard treatment for 3-5 days according to different primary diseases after admission.Their urine was less than 800 mL every day and it met the standard of diuretic resistance.Then the
View details →Arum Etikariena · 2019 · Jurnal Psikologi Undip
In recent years, research on innovation in organizations, particularly innovative work behaviors, has developed considerably. The objective of the study were to examine the role of individual characteristics such as age, gender, educational background, ethnic’s background, tenure and length in current position which presumably would have an impact on the formation of innovative work behaviors. The study is quantitative study with non-experimental design, conducted on 279 respondents working in a Syariah Bank and a television company. The measuring tool used is the Innovative Work Behavior Scal
View details →sara hasani, abolghasem mehrinezhad, Roshanak khodabakhsh pirkalani · 2020 · مجله علوم روانشناختی
Background: Obsessive-compulsive disorder is one of the most common and disabling psychological disorders. Many studies have investigated the effectiveness of mindfulness and exposure on the improvement of obsessive-compulsive disorder, but the key question is which of the two combinations of exposure, mindfulness, and mindfulness of exposure is most effective on obsessive-compulsive disorder in women? Aims: To compare the effects of exposure, mindfulness and mindfulness-exposure consciousness on combined obsessive-compulsive disorder in Arak women. Method: This was a quasi-experimental study
View details →LIU Yanan, WANG Likai, LIU Sisi et al. · 2019 · 口腔疾病防治
Objective To compare the polishing effects of three different polishing systems on machinable compos⁃ ite resins and to provide a basis for the rational selection of polishing systems in the clinic. Methods Block HC, Cerasmart, and Hyramic were fabricated into 90 test pieces. Then, 30 test pieces for each material were randomly divid⁃ ed into 3 groups with 10 pieces per group. The pieces were polished with the Vita Enamic® Polishing Set (Vita group), EVE RA341 composite polishing set (Eve group), and Toboo M elastic ceramic polishing set (Tob group). The surface roughness and gloss of each tes
View details →Tianyu Niu, Tianyu Niu, Zhishuo Liu et al. · 2025 · Frontiers in Cardiovascular Medicine
BackgroundThis study investigates the feasibility and early outcomes of early myocardial reperfusion in patients with type A aortic dissection (TAAD), evaluating its effectiveness and potential benefits compared to traditional cardioplegic arrest techniques.MethodsA retrospective analysis was conducted on 168 patients diagnosed with TAAD who underwent surgery at the General Hospital of the Northern Theater Command in China from January 2021 to July 2024. Patients were divided into two groups: early myocardial reperfusion (EMR group, n = 66) and cardioplegic arrest (CA group, n = 102). Perioper
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