20,211 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Maha N. Mian, Brianna R. Altman, Luna F. Ueno et al. · 2020 · Journal of Psychoactive Drugs
Savoring has covaried inversely with cannabis problems and moderated the association between cannabis use and negative consequences related to use. Research has not yet addressed the acceptability of savoring interventions for cannabis…
View details →Ivana Vranješ, Tinne Vander Elst, Yannick Griep et al. · 2022 · Group & Organization Management
In this study, we investigated whether and how perpetrators of bullying become targets themselves. Building on the notion of bullying as an escalation process and the Conservation of Resources Theory, we hypothesized that following enactment of bullying, people would experience increased relationship conflicts with colleagues, diminishing their sense of control and making them more likely to become exposed to bullying themselves. We tested this idea using longitudinal sequential mediated Structural Equation Modelling in a sample of 1420 Belgian workers. Our results confirmed that enactment of
View details →Jessica A. Blayney, Matthew D. Scalco, Sharon Radomski et al. · 2019 · Psychology of Addictive Behaviors
= 480; 61% female) reported on their alcohol and drug use behaviors across 5 time points spanning 1 calendar year. For many, this year included the transition out of college. Latent growth curve analysis was used to determine whether…
View details →James Foulds, Kim N. T. Ton, Martin A. Kennedy et al. · 2015 · Pharmacogenetics and Genomics
A functional polymorphism rs1799971 (A118G) in the μ-opioid receptor gene (OPRM1) produces an amino acid substitution Asn40Asp, which is believed to influence naltrexone response in nondepressed alcohol-dependent patients. In this study,…
View details →Feride Acar · 2015 · Procedia - Social and Behavioral Sciences
Extant research shows that female managers face significant hurdles in the attainment of top level positions in IT organizations. Recently there have been some examples to women breaking through the glass ceiling to reach to higher…
View details →Guy Assaker, Vincenzo Esposito Vinzi, Peter O’Connor · 2011 · Tourism and Hospitality Research
This study provides insights into a powerful statistical technique to test model invariance across multiple groups. In doing so, it provides insights for policymakers and contributes to the literature on tourism demand forecasting by…
View details →Irene Trilla, Hanna Drimalla, Malek Bajbouj et al. · 2020 · Frontiers in Behavioral Neuroscience
Recent findings suggest a role of oxytocin on the tendency to spontaneously mimic the emotional facial expressions of others. Oxytocin-related increases of facial mimicry, however, seem to be dependent on contextual factors. Given previous literature showing that people preferentially mimic emotional expressions of individuals associated with high (vs. low) rewards, we examined whether the reward value of the mimicked agent is one factor influencing the oxytocin effects on facial mimicry. To test this hypothesis, 60 male adults received 24 IU of either intranasal oxytocin or placebo in a doubl
View details →Stefania Piscopo, Euan R. Brown · 2018 · Small
Abstract Membrane–nanoparticle interactions are important in determining the effects of manufactured nanomaterials on cell physiology and pathology. Here, silica, titanium, zinc, and magnesium oxide nanoparticles are screened against human…
View details →Chang Yu, Ning Zhang, Weikang Zhu et al. · 2019 · Evidence-based Complementary and Alternative Medicine
Objectives . To evaluate the safety of moxa smoke, especially to provide quantitative information and details for the occupational prevention of acupuncturists. Methods . We combined the questionnaire-based cross-sectional survey and lung function testing-based historical retrospective cohort research to investigate the safety of moxa smoke exposure (MSE) among acupuncturists. A mathematical regression model was established to quantitatively evaluate the relationship between moxa smoke exposure and the respiratory health of the acupuncturist. The smoke exposure time of the acupuncturist and th
View details →Jennifer Zou, Jinjing Zhou, Sarah Faller et al. · 2022 · G3 Genes Genomes Genetics
Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with complex human traits, but only a fraction of variants identified in discovery studies achieve significance in replication studies. Replication in genome-wide association studies has been well-studied in the context of Winner's Curse, which is the inflation of effect size estimates for significant variants due to statistical chance. However, Winner's Curse is often not sufficient to explain lack of replication. Another reason why studies fail to replicate is that there are fundamental difference
View details →Linda Liu, Zachary Burchill, Michael K. Tanenhaus et al. · 2017 · eScholarship (California Digital Library)
Sentence understanding is affected by recent experience. Animportant open question is whether this reflects adaptationto the statistics of the input. Support for this hypothesiscomes from the recent finding that listeners can…
View details →Zofia Strojny, Rafał Rutkowski, Alina Kanikowska et al. · 2021 · Nutrients
Background: Chronotype is the pattern of the circadian rhythm that allows an individual to optimize times of sleep and activity. It has been observed that chronotypes may associate with some conditions and diseases, including obesity. It is not known, however, whether chronotypes determine the effectiveness of weight loss regimens. Therefore, in the present study, we compared the outcomes of a 3-week moderate calorie restriction undertaken by individuals with obesity under the same controlled hospital conditions. Methods: A total of 131 participants with obesity (median BMI 40.0) were studied.
View details →Wan Azani Mustafa, Haniza Yazid, Hiam Alquran et al. · 2024 · PLoS ONE
Weld defect inspection is an essential aspect of testing in industries field. From a human viewpoint, a manual inspection can make appropriate justification more difficult and lead to incorrect identification during weld defect detection. Weld defect inspection uses X-radiography testing, which is now mostly outdated. Recently, numerous researchers have utilized X-radiography digital images to inspect the defect. As a result, for error-free inspection, an autonomous weld detection and classification system are required. One of the most difficult issues in the field of image processing, particu
View details →Shanshan Jiang, Jaka Sunarso, Wei Zhou et al. · 2013 · Journal of Materials Chemistry A
Layered oxides of Sr4Fe4Co2O13 (SFC2) which contains alternating perovskite oxide octahedral and polyhedral oxide double layers are attractive for their mixed ionic and electronic conducting and oxygen reduction reaction properties. In…
View details →Loet Leydesdorff, Caroline S. Wagner, Lin Zhang · 2021 · Journal of Data and Information Science
Abstract Purpose Building on Leydesdorff, Bornmann, and Mingers (2019), we elaborate the differences between Tsinghua and Zhejiang University as an empirical example. We address the question of whether differences are statistically…
View details →Dapeng Liu, Heinz Roland Weistroffer · 2020 · Journal of Computer Information Systems
Trust, such as trust in a technology or believing that a technology has trustworthy utility, manifests its importance by affecting user behaviors toward information systems (IS). There is no dearth of evidence showing that the effect of…
View details →Michael Benatar, Christopher McDermott, Martin R. Turner et al. · 2024 · Brain
There is a long history in amyotrophic lateral sclerosis (ALS) of promoting therapies based on phase 2 data, which then fail in phase 3 trials. Experience suggests that studies of 6 months in duration are too short, especially with…
View details →Kaylin Ratner, Anthony L. Burrow, Felix Thoemmes · 2016 · Royal Society Open Science
Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman, Trent & King (2013 Psychol. Sci. 24 , 991–998 ( doi:10.1177/0956797612465878 )), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodol
View details →Jingxiang Song, Xiaohuang Tu, Bing Wang et al. · 2014 · BMC Gastroenterology
BACKGROUND: To evaluate the safety, efficacy and outcomes of fast-track rehabilitation applied to gastric cancer proximal, distal and total gastrectomy. METHODS: Eighty consecutive patients undergoing gastric cancer resection performed by a single surgeon, received perioperative multimodal rehabilitation. Demographic and operative data, gastrointestinal function, postoperative hospital stays, surgical and general complications and mortality were assessed prospectively. RESULTS: Of the 80 patients (mean age 56.3 years), 10 (12.5%) received proximal subtotal gastrectomy (Billroth I), 38 (47.5%)
View details →Mahima Chillakanti, Elaine Young, April Hopcroft et al. · 2024 · touchREVIEWS in Endocrinology
AID systems can achieve near-desired glycaemic targets with minimal hypoglycaemia in pregnant women with T1D. Randomized controlled trials are needed to confirm these findings and to win FDA indications in pregnancy.
View details →Xiao Xuan Xing, Chen Zhu, Yan Chu et al. · 2021 · BMC Gastroenterology
BACKGROUND: Perioperative patients are at risk of developing stress ulcers (SU), which can cause clinically important bleeding. Stress ulcer prophylaxis (SUP) is widely applied to the patients in Intensive care unit (ICU) as well as the general ward, so it may lead to overmedication. However, there have been no surveys regarding SUP knowledge or prescribing habits. OBJECTIVE: Our study assessed the knowledge, attitudes, and prescribing behavior of the surgeons toward perioperative patients regarding SUP and determined factors associated with low knowledge and high level of prescribing behavior
View details →Shih-Hong Chen, Wing-Sum Chan, Chih‐Min Liu et al. · 2020 · Annals of Intensive Care
Abstract Background Endotoxins can induce an excessive inflammatory response and result in microcirculatory dysfunction. Polymyxin-B hemoperfusion (PMX-HP) has been recognized to effectively remove endotoxins in patients with sepsis and…
View details →Yudan Wang, Litian Liu, Xinning Li et al. · 2022 · Journal of Interventional Cardiology
Background: Mortality after percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) patients with cardiogenic shock (CS) remains high. However, the real-world risk factors for mortality in these patients are poorly defined. Objective: The aim of this study is to establish a clinical prognostic nomogram for predicting in-hospital mortality after primary PCI in STEMI patients with CS. Methods: This retrospective, multicenter, observational study included STEMI patients with CS who underwent PCI at 39 hospitals in Hebei Province from January 2018 to December 2019. A
View details →Kazuhiro Yamamoto · 2017 · Yonago acta medica
Heart failure with preserved ejection fraction is a socioeconomic burden in Japan as well as other developed countries. Diuretics are widely used to attenuate symptoms and signs of congestion in both heart failure with preserved and…
View details →Mao Uematsu, Yoko Tsukita, Takehiro Tozuka et al. · 2023 · Journal of Clinical Oncology
9012 Background: Immune checkpoint inhibitor (ICI) plus chemotherapy is now a standard treatment for non-small cell lung cancer (NSCLC) without targetable oncogene alternations. However, the efficacy and safety of ICI plus chemotherapy…
View details →Sukeshi Patel Arora, Laura Tenner, John Sarantopoulos et al. · 2019 · Journal of Clinical Oncology
3551 Background: Agents targeting the angiogenic pathway have been a cornerstone therapy in mCRC. In chemo-refractory mCRC, RGF, an oral multikinase inhibitor with considerable angiogenic inhibition, has shown modest effects on survival.…
View details →Maya Gopalakrishnan, Satyendra Khichar, Suman Saurabh et al. · 2022 · Monaldi Archives for Chest Disease
Awake self-proning is being used widely as respiratory support in COVID-19 hypoxemia, in resource-limited settings. We aimed to investigate the effectiveness of early awake self-proning in preventing mortality and the need for intubation…
View details →Sean Haimowitz, David Cohen, Aatin K. Dhanda et al. · 2022 · The Laryngoscope
OBJECTIVES: Mucosal melanoma (MM) is a rare malignancy that can present in the head and neck (H&N). The Oral cavity is the second most common primary site in the H&N after sinonasal mucosa. This study investigates the impact of demographic…
View details →Andrew Goudie, Douglas H.J. Elder, Harshal Deshmukh et al. · 2014 · European Journal of Heart Failure
BACKGROUND: The use of oral anticoagulation in patients with heart failure in sinus rhythm remains controversial as previous large randomized controlled trials (RCTs) have not shown a survival benefit. However, heterogeneity exists among…
View details →Sidsel Pedersen, Søren Møller, Marco Donia et al. · 2022 · Melanoma Research
Novel medical therapies have revolutionized outcome for patients with melanoma. However, patients with melanoma brain metastases (MBM) still have poor survival. Data are limited as these patients are generally excluded from clinical…
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