OPRM1 genotype and naltrexone response in depressed alcohol-dependent patients
James Foulds; Kim N. T. Ton; Martin A. Kennedy; Simon J. Adamson; Roger Mulder; J. Douglas Sellman · 2015 · Pharmacogenetics and Genomics
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
A functional polymorphism rs1799971 (A118G) in the μ-opioid receptor gene (OPRM1) produces an amino acid substitution Asn40Asp, which is believed to influence naltrexone response in nondepressed alcohol-dependent patients. In this study,…
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Metadata source: OpenAlex · DOI 10.1097/fpc.0000000000000128