e-ISSN: Pending

Browse the failure-mode index

19,814 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessPsychology

The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman, Trent & King (2013)

Kaylin Ratner, Anthony L. Burrow, Felix Thoemmes · 2016 · Royal Society Open Science

Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman, Trent & King (2013 Psychol. Sci. 24 , 991–998 ( doi:10.1177/0956797612465878 )), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodol

View details →
Negative / Null Result ReportOpen accessEngineering

The relevance of preferential flow in catchment scale simulations: Calibrating a 3D dual‐permeability model using DREAM

Luisa Hopp, Barbara Glaser, Julian Klaus et al. · 2019 · Hydrological Processes

Abstract The occurrence of preferential flow in the subsurface has often been shown in field experiments. However, preferential flow is rarely included in models simulating the hydrological response at the catchment scale. If it is…

View details →
Negative / Null Result ReportSocial Sciences

Effects of Information Veracity and Message Frames on Information Dissemination: A Case Study of 2016 Zika Epidemic Discussion on Twitter

Qian Xu, Shi Chen, Lida Safarnejad · 2020 · Health Communication

By taking the 2016 Zika outbreak as a case study, this research examines how information veracity (true information vs. misinformation) interacted with message frames to influence the dissemination of information about Zika through retweet…

View details →
Negative / Null Result ReportOpen accessChemistry

Net Analyte Signal-based Quantitative Determination of Fusel Oil in Korean Alcoholic Beverage Using FT-NIR Spectroscopy

Santosh Lohumi, Lalit Mohan Kandpal, Young Wook Seo et al. · 2016 · Journal of Biosystems Engineering

Purpose: Fusel oil is a potent volatile aroma compound found in many alcoholic beverages. At low concentrations, it makes an essential contribution to the flavor and aroma of fermented alcoholic beverages, while at high concentrations, it…

View details →
Negative / Null Result ReportEarth and Planetary Sciences

Dissipative models of swell propagation across the Pacific

Camille Zaug, John D. Carter · 2021 · Studies in Applied Mathematics

Abstract Ocean swell plays an important role in the transport of energy across the ocean, yet its evolution is not well understood. In the late 1960s, the nonlinear Schrödinger (NLS) equation was derived as a simplified model for the…

View details →
Negative / Null Result ReportOpen accessMedicine

Machine Learning Did Not Outperform Conventional Competing Risk Modeling to Predict Revision Arthroplasty

Jacobien H. F. Oosterhoff, Anne de Hond, Rinne M Peters et al. · 2024 · Clinical Orthopaedics and Related Research

BACKGROUND: Estimating the risk of revision after arthroplasty could inform patient and surgeon decision-making. However, there is a lack of well-performing prediction models assisting in this task, which may be due to current conventional…

View details →
Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance

Risk-Return Analysis of the Biopharmaceutical Industry as Compared to Other Industries

Cedric Popa, Karel Holvoet, Tessa Van Montfort et al. · 2018 · Frontiers in Pharmacology

Background: Profits in the biopharmaceutical industry have been scrutinized in social debate. However, drawing conclusions based on industry profitability only is inappropriate as such an analysis does not account for risks faced by investors. This study aims to measure risks and returns in the biopharmaceutical industry and investigates whether risk-adjusted return on investment in the biopharmaceutical industry is higher than that in other industries. Methods: To enable appropriate comparison, we identified six benchmark industries with characteristics that match those of the biopharmaceutic

View details →
Negative / Null Result ReportOpen accessMedicine

Histogram analysis from stretched exponential model on diffusion-weighted imaging: evaluation of clinically significant prostate cancer

Eun-Ju Kim, Chan Kyo Kim, Hyun Soo Kim et al. · 2020 · British Journal of Radiology

Objective: To evaluate the usefulness of histogram analysis of stretched exponential model (SEM) on diffusion-weighted imaging in evaluating clinically significant prostate cancer (CSC). Methods: A total of 85 patients with prostate cancer…

View details →
Negative / Null Result ReportOpen accessEnvironmental Science

Both species richness and growth forms affect nutrient removal in constructed wetlands: A mesocosm experiment

Yumei Luo, Quan Chen, Fan Liu et al. · 2023 · Frontiers in Ecology and Evolution

Introduction Plant richness is thought to improve the function of constructed wetlands (CWs), but most CWs are planted with monocultures, with only a few employed polycultures, which have drawn contradictory conclusions. We suppose functional diversity is the key to better performance of plant communities and hypothesize that CWs planted with diverse growth forms are superior in plant growth and nutrient removal. Methods In this study, six emergent plant species categorized into slender type ( Schoenoplectus tabernaemontani, Typha orientalis ), fan type ( Iris sibirica, Acorus calamus ) and la

View details →
Negative / Null Result ReportOpen accessAgricultural and Biological Sciences

Genomic and phenomic prediction for soybean seed yield, protein, and oil

Liza Van der Laan, Kyle Parmley, Mojdeh Saadati et al. · 2025 · The Plant Genome

Developments in genomics and phenomics have provided valuable tools for use in cultivar development. Genomic prediction (GP) has been used in commercial soybean [Glycine max L. (Merr.)] breeding programs to predict grain yield and seed…

View details →
Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology

Increasing imputation and prediction accuracy for Chinese Holsteins using joint Chinese–Nordic reference population

Peipei Ma, Mogens Sandø Lund, Xiangdong Ding et al. · 2014 · Journal of Animal Breeding and Genetics

This study investigated the effect of including Nordic Holsteins in the reference population on the imputation accuracy and prediction accuracy for Chinese Holsteins. The data used in this study include 85 Chinese Holstein bulls genotyped…

View details →
Negative / Null Result ReportOpen accessMedicine

Results of the Kigali Imbereheza Project: A 2-Arm Individually Randomized Trial of TI-CBT Enhanced to Address ART Adherence and Mental Health for Rwandan Youth Living With HIV.

Geri R. Donenberg, Jessica Fitts, Charles Ingabire et al. · 2022 · PubMed

BACKGROUND: Adolescents living with HIV have elevated mental distress and suboptimal antiretroviral therapy (ART) adherence. SETTING: Two urban clinics in Kigali, Rwanda. METHODS: A 2-arm individual randomized controlled trial compared…

View details →
Negative / Null Result ReportOpen accessNeuroscience

Majority language skill, not measures of bilingualism, predicts executive attention in bilingual children

David Giguere, Daniel J. Dickson, Michelle K. Tulloch et al. · 2021 · Journal of Experimental Child Psychology

Evidence is mixed regarding whether and why bilingual children might be advantaged in the development of executive functions. Five preregistered hypotheses regarding sources of a bilingual advantage were tested with data from 102 Spanish-English bilingual children and 25 English monolingual children who were administered a test of executive attention, the flanker task, at 7, 8, and 9 years of age. Measures of the children's early and concurrent bilingual exposure and their concurrent English and Spanish skill were available from a larger longitudinal study in which these children participated.

View details →
Negative / Null Result Report

No clinically significant difference in postoperative pain and side effects comparing conventional and enhanced recovery total hip arthroplasty with early mobilization

Jan Reinhard, Melanie Schindler, Franziska Leiss et al. · 2023 · Archives of Orthopaedic and Trauma Surgery

Abstract Introduction Enhanced recovery after surgery (ERAS) leads to less morbidity, faster recovery, and, therefore, shorter hospital stays. The expected increment of primary total hip arthroplasty (THA) in the U.S. highlights the need…

View details →
Negative / Null Result Report

Single-ion induced surface modifications on hydrogen-covered Si(001) surfaces—significant difference between slow highly charged and swift heavy ions

C Länger, P Ernst, M Bender et al. · 2021 · New Journal of Physics

Abstract Hydrogen-covered Si(001) surfaces were exposed to swift heavy ions (SHI) and slow highly charged ions (HCI). Using scanning tunneling microscopy as analysis tool, the ion-induced modifications on the surface were resolved on the…

View details →
Negative / Null Result Report

Significant difference of differential expression pyroptosis-related genes and their correlations with infiltrated immune cells in sepsis

Li Wang, Jiting Zhang, Li Zhang et al. · 2022 · Frontiers in Cellular and Infection Microbiology

Background Sepsis is regarded as a life-threatening organ dysfunction syndrome that responds to infection. Pyroptosis, a unique form of programmed cell death, is characterized by inflammatory cytokine secretion. Recently, an increasing…

View details →
Negative / Null Result Report

Observational study of the implementation of telephone advice nursing in Sweden: did callers follow recommendations and did the rate of healthcare visits change?

Amanda Sundberg, Anna Carin Wahlberg, Niklas Zethraeus et al. · 2021 · BMJ Open

Objectives Telephone advice nursing is introduced in many countries with one key aim being a reduction of avoidable healthcare visits. The aim of this study was to explore whether callers to a telephone advice nursing service followed the…

View details →
Negative / Null Result ReportOpen accessComputer Science

Noise Reduction in EEG Signals using Convolutional Autoencoding Techniques

Conor Hanrahan · 2019 · ARROW@Dublin Institute of Technology (Dublin Institute of Technology)

The presence of noise in electroencephalography (EEG) signals can significantly reduce the accuracy of the analysis of the signal. This study assesses to what extent stacked autoencoders designed using one-dimensional convolutional neural…

View details →
Negative / Null Result ReportOpen accessMedicine

“Fast track” rehabilitation after gastric cancer resection: experience with 80 consecutive cases

Jingxiang Song, Xiaohuang Tu, Bing Wang et al. · 2014 · BMC Gastroenterology

BACKGROUND: To evaluate the safety, efficacy and outcomes of fast-track rehabilitation applied to gastric cancer proximal, distal and total gastrectomy. METHODS: Eighty consecutive patients undergoing gastric cancer resection performed by a single surgeon, received perioperative multimodal rehabilitation. Demographic and operative data, gastrointestinal function, postoperative hospital stays, surgical and general complications and mortality were assessed prospectively. RESULTS: Of the 80 patients (mean age 56.3 years), 10 (12.5%) received proximal subtotal gastrectomy (Billroth I), 38 (47.5%)

View details →