19,810 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
A Ovental, R Marom, E Botzer et al. · 2014 · Acta Paediatrica
Abstract Aim The US Food and Drug Administration has said that oral preparations containing benzocaine should only be used in infants under strict medical supervision, due to the rare, but potentially fatal, risk of methemoglobinemia. This…
View details →Thomas Kubiszyn, Sarah S. Mire, Sonia Dutt et al. · 2012 · School Psychology Quarterly
Some side effects (SEs) of increasingly prescribed psychotropic medications can impact student performance in school. SE risk varies, even among drugs from the same class (e.g., antidepressants). Knowing which SEs occur significantly more…
View details →Carlos Morales, Percy Marquina Feldman · 2013 · Journal of CENTRUM Cathedra (JCC) The Business and Economics Research Journal
An extensive literature review reveals various authors acknowledge skills have an impact on entrepreneurial success. However, a lack of consensus regarding the main skills an entrepreneur needs is apparent. In this study, a contribution is made to the debate with empirical data and analysis, in two steps: by testing mean differences and reducing data with a principal components analysis. A sample of 394 potential entrepreneurs was administered the SAT-ECENT questionnaire, testing four skills: readiness to change, learning capacity, impact on people, and stress tolerance. The questionnaires wer
View details →Hadgu Gerensea, Rajalakshmi Murugan · 2016 · Advances in Nursing
Background . Children’s decisions concerning investigation and treatment may be based on the results of temperature alone. Although the accuracy of axillary temperature measurement is affected by a number of factors, device dwell time and device type are common. Objective . Compare body temperature between glass mercury thermometer (GMT) and digital thermometer (DT). Method . Comparative descriptive study was used. A total of 101 samples were taken with convenient sampling technique, but 98 were analyzed. Statistical significance (p<0.01) and clinical significance (MD≥0.2°C) were used in th
View details →Daniel R. Principe · 2022 · Scientific Reports
Abstract Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy and are now the preferred treatment for several tumor types. Though ICIs have shown remarkable efficacy in several cancer histologies, in many cases providing…
View details →Nikola Vučinić, R. Shane Tubbs, Mirela Erić et al. · 2019 · Clinical Anatomy
The appearance of the face is one of the most important factors influencing our perception of beauty. However, few studies have attempted to quantitate what one perceives as beauty. Therefore, this study was conducted with the goal of…
View details →Vanessa Bogle, Catherine Sykes · 2011 · Journal of Health Psychology
This review aims to assess the effectiveness of psychological interventions for treating childhood obesity. Firm conclusions about the effectiveness of psychological interventions to treat childhood obesity remain unclear. Based on current…
View details →Tibor M. Szikszay, Wacław M. Adamczyk, Janina Panskus et al. · 2023 · PLoS ONE
A frequently used paradigm to quantify endogenous pain modulation is offset analgesia, which is defined as a disproportionate large reduction in pain following a small decrease in a heat stimulus. The aim of this study was to determine whether suggestion influences the magnitude of offset analgesia in healthy participants. A total of 97 participants were randomized into three groups (hypoalgesic group, hyperalgesic group, control group). All participants received four heat stimuli (two constant trials and two offset trials) to the ventral, non-dominant forearm while they were asked to rate the
View details →Renee W. Y. Chan, Louisa Chan, Chris Ka Pun Mok et al. · 2017 · Scientific Reports
H9N2 viruses are the most widespread influenza viruses in poultry in Asia. We evaluated the infection and tropism of human and avian H9 influenza virus in the human respiratory tract using ex vivo respiratory organ culture. H9 viruses infected the upper and lower respiratory tract and the majority of H9 viruses had a decreased ability to release virus from the bronchus rather than the lung. This may be attributed to a weak neuraminidase (NA) cleavage of carbon-6-linked sialic acid (Sia) rather than carbon-3-linked Sia. The modified cleavage of N-acetlylneuraminic acid (Neu5Ac) and N-glycolylne
View details →Sarah Agmon, Srinivas Kunta, Mery Dafny-Yelin et al. · 2022 · Crop Science
Abstract Stem rot, caused by the Sclerotium rolfsii , imposes severe yield losses in peanuts ( Arachis hypogaea L.) worldwide. Breeding for resistance is challenging because not enough is known about mechanisms for resistance. The goals of…
View details →Alexander Falkenhagen, Marno Huyzers, Alberdina A. van Dijk et al. · 2021 · Viruses
The rotavirus species A (RVA) capsid contains the spike protein VP4, which interacts with VP6 and VP7 and is involved in cellular receptor binding. The capsid encloses the genome consisting of eleven dsRNA segments. Reassortment events can result in novel strains with changed properties. Using a plasmid-based reverse genetics system based on simian RVA strain SA11, we previously showed that the rescue of viable reassortants containing a heterologous VP4-encoding genome segment was strain-dependent. In order to unravel the reasons for the reassortment restrictions, we designed here a series of
View details →Maisam Wahbah, Omar Alhussein, Tarek H. M. EL-Fouly et al. · 2018
An accurate statistical estimation of wind speed probability density at a given site is crucial when making power network planning decisions involving wind generation resources. The use of parametric probability density functions, such as…
View details →John E. Kiat, Ai Rene Ong, Asha Ganesan · 2017 · Educational Psychology
Multiple-choice questions (MCQs) play a key role in standardised testing and in-class assessment. Research into the influence of within-item response order on MCQ characteristics has been mixed. While some researchers have shown…
View details →Md Sahabul Alam, Fabrice Labeau, Georges Kaddoum · 2016 · IEEE Transactions on Communications
In this paper, we consider the performance analysis of a decode-and-forward (DF) cooperative relaying (CR) scheme over channels impaired by bursty impulsive noise. Although the Middleton class-A model and the Bernoulli-Gaussian model give…
View details →Cécile Hérate, Clarisse Vigne, Carolin A. Guenzel et al. · 2016 · Retrovirology
BACKGROUND: Through incorporation into virus particles, the HIV-1 Vpr protein participates in the early steps of the virus life cycle by influencing the reverse transcription process. We previously showed that this positive impact on reverse transcription was related to Vpr binding to the uracil DNA glycosylase 2 enzyme (UNG2), leading to enhancement of virus infectivity in established CD4-positive cell lines via a nonenzymatic mechanism. RESULTS: We report here that Vpr can form a trimolecular complex with UNG2 and the p32 subunit (RPA32) of the replication protein A (RPA) complex and we expl
View details →Christopher J. Ferguson · 2018 · Annual Review of Law and Social Science
During the early 2000s, several states and municipalities sought to regulate minors’ access to violent video games owing to perceived harms to minors. The resultant case law, culminating in the US Supreme Court case Brown v. EMA (2011),…
View details →Suzanna Forwood, Amy L. Ahern, Gareth J Hollands et al. · 2013 · PLoS ONE
OBJECTIVE: Previous studies have shown that estimations of the calorie content of an unhealthy main meal food tend to be lower when the food is shown alongside a healthy item (e.g. fruit or vegetables) than when shown alone. This effect has been called the negative calorie illusion and has been attributed to averaging the unhealthy (vice) and healthy (virtue) foods leading to increased perceived healthiness and reduced calorie estimates. The current study aimed to replicate and extend these findings to test the hypothesized mediating effect of ratings of healthiness of foods on calorie estimat
View details →Christoph Rochlitz, Roger von Moos, Martin Bigler et al. · 2014 · Journal of Clinical Oncology
518 Background: Bevacizumab combined with chemotherapy has been shown to improve response rate and PFS in metastatic breast cancer. The aim of our study was to demonstrate decreased toxicity of metronomic chemotherapy/bevacizumab when…
View details →Larissa Bomfim, Isabela Ramos · 2020 · The FASEB Journal
In insects, synthesis and deposition of the chorion (eggshell) are performed by the professional secretory follicle cells (FCs) that surround the oocytes in the course of oogenesis. Here, we found that ULK1/ATG1, an autophagy-related…
View details →X. J. Li, Desheng Zhao, Desheng Jiang et al. · 2014 · Journal of Applied Physics
The significant effect of the thickness of Ni film on the performance of the Ohmic contact of Ni/Au to p-GaN is studied. The Ni/Au metal films with thickness of 15/50 nm on p-GaN led to better electrical characteristics, showing a lower…
View details →Yvette A. Girard, Christine K. Johnson, Heather Fritz et al. · 2015 · International Journal for Parasitology Parasites and Wildlife
Tissue-cyst forming coccidia in the family Sarcocystidae are etiologic agents of protozoal encephalitis in marine mammals including the federally listed Southern sea otter (Enhydra lutris). California sea lions (Zalophus californianus),…
View details →Müge Özbek, Annette Bohn, Dorthe Berntsen · 2020 · Applied Cognitive Psychology
Summary We have limited knowledge as to whether the phenomenological differences between episodic memories, counterfactuals, and future projections show the same pattern across age groups and diverse samples. Here we compared the…
View details →Noor Azlinna Azizan, Bahari Mohamed · 2013 · Asian journal of social sciences & humanities
This study focuses on the effects of perceived service quality on patient satisfaction in a public hospital. Data was collected from 109 respondents that experienced the hospital service. Using a PLS-SEM tool, the hypothesized effects…
View details →Meghan Roche, Andrea Carr, In Heok Lee et al. · 2016 · Journal of Career Assessment
This study explored the measurement equivalence of the Career Indecision Profile (CIP) in a Chinese sample with both U.S. and South Korean samples. Past measurement invariance research on the CIP in four international samples (Icelandic…
View details →Waylon J. Hastings, Laura Etzel, Christine M. Heim et al. · 2022 · Aging
Various approaches exist to assess population differences in biological aging. Telomere length (TL) is one such measure, and is associated with disease, disability and early mortality. Yet, issues surrounding precision and reproducibility are a concern for TL measurement. An alternative method to estimate TL using DNA methylation (DNAmTL) was recently developed. Although DNAmTL has been characterized in adult and elderly cohorts, its utility in pediatric populations remains unknown. We examined the comparability of leukocyte TL measurements generated using qPCR (absolute TL; aTL) to those esti
View details →Jon P. Beckmann, Sarah H. Olson, Renee G. Seidler et al. · 2016 · Global Ecology and Conservation
To meet societal demands for energy, ∼50,000 gas sites are developed annually in North America, among which many are in western less-developed and wildlife rich areas. To evaluate effects of increasing energy infrastructure requires…
View details →Alberto Zanchetti · 2016 · Journal of Hypertension
The articles published in the current issue of the Journal of Hypertension focus on risk factors for the development of hypertension and on the relationship of hypertension with cardiovascular disease. Two articles illustrate the role of…
View details →John Hitz, Elaine J. Francis · 2016 · Linguistics
Abstract Gibson and Fedorenko (2013, The need for quantitative methods in syntax and semantics research, Language and Cognitive Processes 28(2), 88–124) have argued against the continued use of informally collected acceptability judgments…
View details →Jaroslava Durdiaková, Varun Warrier, Simon Baron‐Cohen et al. · 2014 · Molecular Autism
BACKGROUND: Autism Spectrum Conditions (ASC) are a group of developmental conditions which affect communication, social interactions and behaviour. Mitochondrial oxidative dysfunction has been suggested as a mechanism of autism based on the results of multiple genetic association and expression studies. SLC25A12 is a gene encoding a calcium-binding carrier protein that localizes to the mitochondria and is involved in the exchange of aspartate for glutamate in the inner membrane of the mitochondria regulating the cytosolic redox state. rs2056202 SNP in this gene has previously been associated w
View details →Matthew A. Masten, Alexandre Poirier · 2026 · American Economic Review
We show that, depending on how the impact of omitted variables is measured, it can be substantially easier for omitted variables to flip coefficient signs than to drive them to zero. This behavior occurs with “Oster's delta” (Oster 2019a),…
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