The gut-lung axis: effects and mechanisms of gut microbiota on pulmonary diseases
Jiayi Liu; Weichen Hong; Zhendong Sun; Shuyu Zhang; Chenyu Xue; Na Dong · 2026 · Frontiers in Immunology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
The proposal of the gut-lung axis has profoundly reshaped our understanding of the mechanisms underlying respiratory diseases. As a crucial component of this axis, the gut microbiota plays a central role in pulmonary immune regulation through inter-organ communication mediated by metabolic products. However, a systematic integration of mechanisms explaining how gut microbes achieve precise cross-organ immune regulation remains elusive. Existing research predominantly focuses on descriptive observations, such as the association between early-life microbiota dysbiosis and an increased risk of as
Abstract by Jiayi Liu; Weichen Hong; Zhendong Sun; Shuyu Zhang; Chenyu Xue; Na Dong, Frontiers in Immunology (2026) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3389/fimmu.2025.1693964