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49 real negative results, null findings, and replication failures in Nursing · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessNursing

Selenium Nanoparticles as Versatile Delivery Tools

Amir Nasrolahi Shirazi, Rajesh Vadlapatla, Ajoy Koomer et al. · 2025 · Pharmaceutics

Selenium nanoparticles (SeNPs) have emerged as promising metal-based nanoparticles for drug delivery due to their unique physicochemical properties, intrinsic bioactivity, and biocompatibility. SeNPs offer a lower toxicity, higher bioavailability, and flexibility to be customized for surface chemistry compared to traditional selenium compounds. Advances in synthetic strategies, including chemical reduction, green biosynthesis, and surface functionalization with polymers, peptides, or ligands, have improved their stability, targeting capability, and circulation time. SeNP-based systems have dem

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Negative / Null Result ReportOpen accessNursing

Comparison of the effect of acupressure and pilates-based exercises on sleep quality of postmenopausal women: A randomized controlled trial

Maryam Ahmadinezhad, Marzieh Kargar, Fatemeh Vizeshfar et al. · 2017 · Iranian Journal of Nursing and Midwifery Research

Background: Postmenopausal women experience a variety of symptoms, among which sleep disorder is one of the most common problems. Acupressure and Pilates exercise programs are effective nonpharmaceutical treatments which can improve sleep quality. In the present study, we aimed to compare the effects of acupressure and Pilates-based exercises on the sleep quality of postmenopausal women referred to medical clinics. Materials and Methods: In this single-blinded randomized controlled clinical trial, we recruited 108 women aged 40–60 years who were randomly assigned into one control and two inter

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Negative / Null Result ReportOpen accessNursing

The effect of an educational intervention for university students on violence against the elderly using gamification: a non-randomized clinical trial

Juliana Ribeiro da Silva Vernasque, Miriam Fernanda Sanches Alarcon, Daiana Bonfim et al. · 2025 · Revista Latino-Americana de Enfermagem

Objective: to evaluate the impact of a gamified educational intervention on violence against the elderly on the knowledge, perceptions and attitudes of university students. Method: a non-randomized clinical trial involving 44 university students from the health sciences, humanities and exact sciences, with 22 in the intervention group and 22 in the control group. The intervention group participated in hybrid activities on gamification applied to the topic of violence against the elderly. The evaluation was conducted using thematic cases validated by experts, with statistical analysis using Chi

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Negative / Null Result ReportOpen accessNursing

Maternal Factors in Stunting Among Vulnerable Children

Stefanus Mendes Kiik, Muhammad Saleh Nuwa · 2021 · Jurnal Keperawatan Indonesia

Children with stunting in Indonesia and other low-middle countries remains a serious problem. This study aimed to identify the association between maternal education, maternal age, maternal height, preceding birth interval, and ANC clinic visits and stunting among vulnerable children in Kupang Regency, Indonesia. A cross-sectional study was conducted of two villages in Kupang Regency. The study sample comprised female ex-refugees from Timor Leste who had children aged 24–59 months. The subjects were chosen using consecutive sampling, with a total number of 154. Data were collected from both pr

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Negative / Null Result ReportOpen accessNursing

Cultural adaptation and validation of the "Diabetes Quality of Life for Youths" measure of Ingersoll and Marrero into Brazilian culture Adaptación cultural y validación para la cultura brasileña del instrumento "Diabetes Quality of Life for Youths" de Ingersoll y Marrero Adaptação cultural e validação da medida "Diabetes Quality of Life for Youths" de Ingersoll e Marrero para a cultura brasileira

Tatiana de Sá Novato, Sonia Aurora Alves Grossi, Miako Kimura · 2008 · Revista Latino-Americana de Enfermagem

The aim of this study was to adapt the "Diabetes Quality of Life for Youths (DQOLY)" measure into Brazilian culture and to analyze its psychometric properties. The cross-cultural adaptation included the phases of translation, backtranslation, committee review, and pretesting. The adapted instrument was applied to 124 type 1 diabetes mellitus´adolescents. The reliability results showed adequate Cronbach's alpha coefficients (0.8695 for Satisfaction domain, 0.8658 for Impact, 0.8387 for Worries and 0.9333 for total), with the exclusion of 3 inconsistent items. The test-retests showed no si

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Negative / Null Result ReportOpen accessNursing

Association Between Serum 25-Hydroxyvitamin D Levels and Gross Motor Development in Children With Down Syndrome: An Analytical Cross-Sectional Study

Esmire Tërshnjaku Sadiku, Lence Aleksovska Velickovska, Samire Beqaj et al. · 2026 · Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija

Background. Down syndrome (DS) is associated with delayed gross motor development, and vitamin D deficiency is frequently reported in this population. However, evidence regarding the relationship between vitamin D status and motor development in children with DS is limited. Aim. To examine the association between serum 25-hydroxyvitamin D [25(OH)D] levels and gross motor development in children with DS. Methods. This analytical cross-sectional study included 33 children with DS (13 females and 20 males) aged 1.00–6.56 years (mean age 2.53 ± 1.06 years). Gross motor development was assessed usi

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Negative / Null Result ReportOpen accessNursing

The Relationship between Spiritual Well-Being and Depression in Nursing Students

Z Gharehboghlou, M Adib-Hajbaghery, M Hajimohammad Hoseini · 2016 · نشریه پرستاری ایران

Abstract Background & Aim: Depression is the fourth leading cause of community disability in the world and it has high prevalence among students. Since spirituality is positively associated to physical and mental health, this study aimed to determine the relationship of spiritual well-being and depression among nursing students in Qom and Kashan Universities of Medical Sciences. Materials & Methods: This cross-sectional study was conducted on nursing students of Kashan and Qom Universities of Medical Sciences. Using a two-stage sampling method, 250 nursing students were randomly selected. Data

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Negative / Null Result ReportOpen accessNursing

Compassion Fatigue and Compassion Satisfaction Among Nursing Officers

Parul Sharma, Bindu Shaiju, Jahanara Rahman et al. · 2024 · Indian Journal of Psychiatric Nursing

Introduction: Nurses make up the largest group of health-care workers, so it is important to rule out compassion fatigue (CF) and compassion satisfaction among nursing officers. Methodology: A descriptive study was adopted, and purposive sampling technique was used. The present study’s sample included 134 nursing officers. The data were gathered in January 2022 using the Structured CF Scale and the Structured Compassion Satisfaction Scale. The data were analyzed using descriptive and inferential statistics. Results: The findings of the research revealed that the majority of the nursing officer

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Negative / Null Result ReportOpen accessNursing

Spiritual well-being and hope in the preoperative period of cardiac surgery

Simone Maria Muniz da Silva Bezerra, Eduardo Tavares Gomes, Paulo César da Costa Galvão et al. · Revista Brasileira de Enfermagem

ABSTRACT Objective: To characterize relations between spiritual well-being and hope of patients in the preoperative period of cardiac surgery. Method: Exploratory cross-sectional study with quantitative approach, performed in the infirmaries of a reference hospital in cardiology. We evaluated 69 patients hospitalized in preoperative period of myocardial revascularization, valve repair or replacement. Results: We verified that patients hold relevant scores of hope and welfare in all areas, being the existential well-being significantly lower than the religious one. The average of the spiritual

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Negative / Null Result ReportOpen accessNursing

Assessing the psychometric properties of persian version of Zarit Burden interview among family caregivers of patients with multiple sclerosis

Hajar Haghshenas, Zeinab Jokar, Ladan Zarshenas et al. · 2023 · BMC Nursing

Abstract Background Caring for patients with multiple sclerosis (MS) imposes a great burden on caregivers and affects their lives in various aspects. This study aimed to evaluate the psychometric properties of Persian version of 22-item Zarit Burden Interview (ZBI-22) among family caregivers of patients with MS. Methods This methodological study was conducted in Fars province, southern of Iran. For this purpose, 120 family caregivers were recruited to participate in the study from January to March 2022. Zarit Burden Interview (ZBI) was translated into Persian through forward–backward method. F

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Negative / Null Result ReportOpen accessNursing

Effect of Wearing a Face Mask on Oxygen Saturation among Hemodialysis Patients Versus Healthy Staff Members

Tarek Mahmoud Shaker Mohamed, Hala Mohamed Abdelhamed Ali, Asmaa Sayed Abd-Almageed et al. · 2022 · International Egyptian Journal of Nursing Sciences and Research

Background: COVID-19 represents a major threat to hemodialysis health life, due to their low immunity, it is essential to wear a face mask to protect them against the outbreak of the COVID-19 pandemic. Aim: To evaluate the effect of wearing a face mask on oxygen saturation among hemodialysis patients versus healthy staff members.Methods: Research design: a quasi-experimental research design Setting: dialysis units at Mansoura University and New General Mansoura hospital. Subjects: A purposive sample with a total of 190 patients was classified into two equal groups, entitled hemodialysis patien

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Negative / Null Result ReportOpen accessNursing

Changes in body temperature of critically ill patients submitted to bed bathing: a crossover clinical trial

Luana Vieira Toledo, Bárbara Xavier dos Santos, Patrícia de Oliveira Salgado et al. · Revista Brasileira de Enfermagem

ABSTRACT Objectives: to compare tympanic and axillary body temperature values of critical patients before and after the traditional and dry bed bath. Methods: this is a randomized, open crossover clinical trial conducted with 50 adult critical patients. All patients received both types of bed bathing. The tympanic and axillary temperature values were measured at the beginning and end of the baths. The Wilcoxon test or paired Student’s t test was used. Results: elderly and male patients predominated. There was no significant difference between tympanic temperature medians measured during the tr

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Negative / Null Result ReportOpen accessNursing

Medical Rehabilitation of Children With Idiopathic Scoliosis: Monotherapy or Combined Therapy. A Systematic Literature Review

Nora Kasparaitytė, Juozas Raistenskis, Lina Budrienė et al. · 2025 · Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija

Background. Idiopathic scoliosis is among the most common spinal disorders diagnosed in 1–3% of children and adolescents. Treatment choice is related to disease severity, with a Cobb angle of 20–40°, a corrective brace or phys­iotherapy can stop its progression. However, insufficient research has shown whether combined treatment is better than monotherapy. Aim. To evaluate the effect of combining bracing and physiotherapy to reduce spinal deformity, improve quality of life and lung function, and compare the results with those of monotherapy. Determine the optimal duration of combined rehabilit

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Negative / Null Result ReportOpen accessNursing

Clinical effect of venousaccess ports and PICC in patients with tumor chemotherapy:a systematic evaluation

孔德华, 张蕾, 储静 · 2018 · Huli yanjiu

Abstract Objective:To systematically review the clinical effect of venousaccess ports(VPA/VAP)and peripheral venous catheterization(PICC)in patients with tumor chemotherapy.Methods:Randomized controlled trial(RCT),semirandomized controlled trial,and cohort study of comparison the application effect of VAP and PICC in patients with tumor chemotherapy were retrieved from the Cochrane CDSR,PubMed,Embase,CINAHL,SCIE,Chinese biomedical literatures service system(CBM),Wanfang,and VIP database.According to the inclusion criteria,two researchers selected the literature,extracted the data,and evaluated

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Negative / Null Result ReportOpen accessNursing

External application with Traditional Chinese Medicine in prevention of postoperative fever in patient undergoing surgery for obstructive sleep apnea-hypopnea syndrome (中药敷贴预防阻塞性睡眠呼吸暂停低通气综合征患者术后发热的效果)

YE Yuquan (叶玉泉) · 2021 · 中西医结合护理

Objective To observe the effect of external application with Traditional Chinese Medicine in prevention of postoperative fever (>38 ℃) in patient undergoing surgery for obstructive sleep apnea-hypopnea syndrome. Methods Totally 118 patients undergoing bilateral tonsillectomy/adenoidectomy were randomly divided into the study group and the control group, with 59 cases in each group. All patients received routine care after surgery, and those in the study group were given external application with Traditional Chinese Medicine. The incidence of postoperative fever (>38 ℃) was compared between two

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Negative / Null Result ReportOpen accessNursing

The impact of training on the application of palliative methods for labor pain reduction

Geranmayeh M, Rezaeipour A, Haghani H et al. · 2006 · حیات

Background & Aim: The severe pain of labor is the important cause of fear and anxiety in pregnant women. This study has been performed to evaluate effect of education on midwives practice. Methods & Materials: This is a quasi-experimental study. That was done 59 midwives in the labor wards of non-educational of Guilan University of Medical Sciences Hospital. Data gathered by a questioner, which its validity was done by panel of experts and reliability by test-retest. 59 midwives were chosen by quota sampling and participated in a one-day workshop. Pretest and post-test questioner completed bef

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Negative / Null Result ReportOpen accessNursing

Comparing the Effect of Continuous and Intermittent Irrigation Techniques on Complications of Arterial Catheter and Partial Thromboplastin Time in Patients Following Coronary Artery Bypass Grafting Surgery

Sedigheh Arta, Seyed Reza Mazlom, Shahram Amini et al. · 2017 · Journal of Evidence-Based Care

Background: Different approaches are available to irrigate the arterial catheter, such as continuous and intermittent techniques. However, there is a disagreement regarding the most appropriate method. Aim: this study aimed to compare the effect of two continuous and intermittent irrigation methods on complications of arterial catheter and partial thromboplastin time (PTT) in patients with coronary artery bypass (CABG) surgery. Method: This randomized clinical trial was conducted on 60 participants undergoing coronary artery bypass grafting surgery in open-heart surgery ICU at Imam Reza hospit

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Negative / Null Result ReportOpen accessNursing

The Effect of Education Based on Health Belief Model on Preventive Behaviors Towards Cardiovascular Disease

Nahid Mohammadi, Nasrin Soltani, Roya Amini et al. · 2018 · مراقبت پرستاری و مامایی ابن سینا

Introduction: Cardiovascular diseases are associated with individual behaviors in childhood, adolescence and youth. This article aimed to study the effect of education based on HBM on the prevention of heart disease in female students. Methods:This pre and post-test semi-experimental study which has two groups was conducted on 126 girls of high schools in 2017. A randomized cluster sampling method and relative randomize method were used in the first and second stages respectively. At first both groups completed a questionnaire and then instructions were given to intervention group in three ses

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Negative / Null Result ReportOpen accessNursing

The Effect of Physiotherapy on the Function of the Upper Extremity and Psycho-Emotional State in Women after a Breast Cancer Surgery

Šidlauskaitė Vaida, Eglė Pankaitė · 2019 · Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija

Background. Women breast cancer accounts for 25% of the new cases of cancer diagnosed worldwide and takes the leading place. After breast surgery pain occurs in the wound of the breast, in the armpit area and the hand that reduces the mobility of the shoulder joint, weakens the arm muscle strength, impairs flow of the lymph, which can affect the quality of life and disturb the psycho-emotional state. Physical therapy is applied dealing with these problems. The aim of the research was to estimate the effect of physical therapy on the arm function and psycho-emotional state in women after breast

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