Failure-mode index

Negative results in Neurology. Diseases of the nervous system

33 indexed negative results, null findings, and replication failures in Neurology. Diseases of the nervous system. Each entry is a real published study whose primary finding was negative — learn what already failed before you repeat it.

Browse all 33 in Neurology. Diseases of the nervous system Search the whole index

By typeNegative / Null Result Report 32 Failed Experiment Report 1

Most-cited failures in Neurology. Diseases of the nervous system

Negative / Null Result Report2023

Transient cognitive impairment in the acute phase of stroke – prevalence, risk factors and influence on long-term prognosis in population of patients with stroke (research study – part of the PROPOLIS study)

BMC Neurology

Negative / Null Result Report2026

Impact of early vs. late tracheostomy on clinical outcomes in mechanically ventilated patients with intracerebral hemorrhage extending into the ventricles: a retrospective cohort study based on quantitative assessment of parenchymal and intraventricular hematoma volumes

Frontiers in Neurology

Negative / Null Result Report2015

Changes of Retina Are Not Involved in the Genesis of Visual Hallucinations in Parkinson’s Disease

Parkinson's Disease

Negative / Null Result Report2024

Efficacy analysis of mechanical thrombectomy combined with prolonged mild hypothermia in the treatment of acute middle cerebral artery occlusion: a single-center retrospective cohort study

Frontiers in Neurology

Negative / Null Result Report2024

Clinical characteristics and prognosis analysis of acute symptomatic seizures secondary to autoimmune encephalitis

Frontiers in Neurology

Negative / Null Result Report2026

A binational study of the association between white matter hyperintensities and functional outcome in stroke patients

Frontiers in Neurology

Negative / Null Result Report2015

Comparison of Compliance Rates and Classification of Epileptic Seizures with ILAE 1981, Lüders, ILAE 2001 Epilepsy Classification Systems, Before and After Their Monitorization

Archives of Epilepsy

Negative / Null Result Report2006

Association study of the vesicular monoamine transporter 1 (VMAT1) gene with schizophrenia in a Japanese population

Behavioral and Brain Functions

Negative / Null Result Report2021

Functional outcomes and subjective recovery of jumping to conclusions in schizophrenia

Schizophrenia Research: Cognition

Negative / Null Result Report2023

Placebo effect after visual restitution training: no eye-tracking controlled perimetric improvement after visual border stimulation in late subacute and chronic visual field defects after stroke

Frontiers in Neurology

Negative / Null Result Report2019

Reproductive Cancer Risk Factors in Women With Myotonic Dystrophy (DM): Survey Data From the US and UK DM Registries

Frontiers in Neurology

Negative / Null Result Report2022

Longitudinal evaluation of olfactory function in individuals with Gaucher disease and GBA1 mutation carriers with and without Parkinson's disease

Frontiers in Neurology

Negative / Null Result Report2016

The Effect of Spinal Tap Test on Different Sensory Modalities of Postural Stability in Idiopathic Normal Pressure Hydrocephalus

Dementia and Geriatric Cognitive Disorders Extra

Negative / Null Result Report2015

CSF neurofilament light chain but not FLT3 ligand discriminates Parkinsonian disorders

Frontiers in Neurology

Negative / Null Result Report2023

Deep brain stimulation in a patient with progressive myoclonic epilepsy and ataxia due to potassium channel mutation (MEAK). A case report and review of the literature

Epilepsy & Behavior Reports

Negative / Null Result Report2024

Phosphatidylserine enriched with polyunsaturated n‐3 fatty acid supplementation for attention‐deficit hyperactivity disorder in children and adolescents with epilepsy: A randomized placebo‐controlled trial

Epilepsia Open

Negative / Null Result Report2022

Characteristics of vestibular migraine, probable vestibular migraine, and recurrent vertigo of childhood in caloric and video head impulse tests

Frontiers in Neurology

Failed Experiment Report2011

Fingolimod modulates microglial activation to augment markers of remyelination

Journal of Neuroinflammation

Negative / Null Result Report2022

Memantine for the patients with mild cognitive impairment in Parkinson’s disease: a pharmacological fMRI study

BMC Neurology

Negative / Null Result Report2026

Intracranial and extracranial artery stenosis and clinical outcome of acute ischemic stroke patients receiving intravenous thrombolysis

Frontiers in Neurology

Negative / Null Result Report2020

Association of peripheral neutrophil count with intracranial atherosclerotic stenosis

BMC Neurology

Negative / Null Result Report2021

Association of Trimethylamine N-Oxide and Its Precursor With Cerebral Small Vessel Imaging Markers

Frontiers in Neurology

Negative / Null Result Report2020

The effect of lacosamide on psychiatric comorbidities in patients with epilepsy

Epilepsy & Behavior Reports

Negative / Null Result Report2026

Association of SCN1A and SCN2A Gene Polymorphisms with Antiseizure Medication Responsiveness: A Case-Control Study from Eastern India

Annals of Indian Academy of Neurology

Negative / Null Result Report2021

The global Alzheimer's Association round robin study on plasma amyloid β methods

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring

Negative / Null Result Report2016

The Effect of Hyperhomocysteinemia on Motor Symptoms, Cognitive Status, and Vascular Risk in Patients with Parkinson’s Disease

Parkinson's Disease

Negative / Null Result Report2022

Predictors of preoperative cognitive dysfunction in adults with Moyamoya disease: a preliminary research

BMC Neurology

Negative / Null Result Report2023

Clinical profile and quality of life in myasthenia gravis using MGQOL15 R(Hindi): An Indian perspective

Annals of Indian Academy of Neurology

Negative / Null Result Report2002

An examination of the Apo-1/Fas promoter Mva I polymorphism in Japanese patients with multiple sclerosis

BMC Neurology

Negative / Null Result Report2021

Assessing Fatty Infiltration of Paraspinal Muscles in Patients With Lumbar Spinal Stenosis: Goutallier Classification and Quantitative MRI Measurements

Frontiers in Neurology

Negative / Null Result Report2018

高龄急性轻型缺血性卒中早期阿替普酶静脉溶栓疗效观察 Observation of the Effect of Alteplase Intravenous Thrombolysis in the Early Stage of Acute Mild Ischemic Stroke in the Elderly

Zhongguo cuzhong zazhi

Negative / Null Result Report2018

The m.3243A > G mutation load in hair follicles from different scalp regions of patients with MELAS

Chinese Journal of Contemporary Neurology and Neurosurgery

Negative / Null Result Report2025

Exploring EEG resting state differences in autism: sparse findings from a large cohort

Molecular Autism