Exploring EEG resting state differences in autism: sparse findings from a large cohort
Adam J.O. Dede; Wenyi Xiao; Nemanja Vaci; Michael X. Cohen; Elizabeth Milne · 2025 · Molecular Autism
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The study found no significant effect — useful as a negative control or null benchmark for your own design.
The finding, in one line
“Although many previous reports have pointed to differences between autistic and neurotypical participants in rsEEG, results have failed to replicate, sample sizes have typically been small, and only a small number of variables are reported in each study.”
Abstract
Abstract Background Autism is a complex neurodevelopmental condition, the precise neurobiological underpinnings of which remain elusive. Here, we focus on group differences in resting state EEG (rsEEG). Although many previous reports have pointed to differences between autistic and neurotypical participants in rsEEG, results have failed to replicate, sample sizes have typically been small, and only a small number of variables are reported in each study. Methods Here, we combined five datasets to create a large sample of autistic and neurotypical individuals (n = 776) and extracted 726 variable
Abstract by Adam J.O. Dede; Wenyi Xiao; Nemanja Vaci; Michael X. Cohen; Elizabeth Milne, Molecular Autism (2025) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/s13229-025-00647-3