Negative / Null Result ReportOpen accessMedicine
Sayed Reza Eshaghi, Armindokht Shahsanai, Maryam Mellat Ardakani · 2011 · مجله دانشکده پزشکی اصفهان
Background: Improvement of medical care and decreasing of mortality, have lead to an increase in ageing in Iranian population. The main goal of Active ageing is improving the quality of life. Physical activity is one of the factors that is important to achieve a good quality of life. The aim of this study was to evaluate the physical activity of the elderly in Isfahan. Methods: This cross sectional study was carried out on 350 old residents of Isfahan, Iran between the years 2009-2010. Multi stage cluster sampling technique was used to collect the sample population. Rapid assessment of physica
Negative / Null Result ReportOpen accessOrthopedic surgery
Luyckx Thomas, Wen Zhishen, Kluyskens Louis et al. · 2025 · Journal of Experimental Orthopaedics
Abstract Purpose The primary aim was to evaluate the functional impact of adding lateral extra‐articular tenodesis (LET) to an anterior cruciate ligament (ACL) reconstruction (ACLR). The secondary aim was to assess whether LET provides benefits in muscle strength, patient‐reported outcome measures (PROMs) and return to sport (RTS) pass rate, as well as to examine the influence of meniscal injury on performance in ACLR patients. Methods A retrospective cohort of prospectively collected data on all ACL procedures was performed at AZ Delta Roeselare between 2017 and 2019. The patients followed a
View details →DOI: 10.1002/jeo2.70269 Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Chun Xie, Tao Huang, Yingying Wang et al. · 2025 · Brain Sciences
Backgrounds and Objectives : Obesity presents a significant global public health challenge and is associated with declines in both general and food-related inhibitory control, crucial for maintaining a healthy weight and preventing obesity progression. An increasing body of research suggests that acute aerobic exercise may improve inhibitory function. However, the effects and underlying mechanisms of acute aerobic exercise on both general and food-related inhibition in obese adults remain unclear. This study aimed to explore the potential impacts and underlying neuroelectronic mechanisms of a
View details →DOI: 10.3390/brainsci15010059 Negative / Null Result ReportOpen accessSpecial aspects of education
Markus H. Hefter, Veit Kubik, Kirsten Berthold · 2023 · International Journal of Educational Technology in Higher Education
Abstract In recent years, COVID-19 policy measures massively affected university teaching. Seeking an effective and viable way to transform their lecture material into asynchronous online settings, many lecturers relied on prerecorded video lectures. Whereas researchers in fact recommend implementing prompts to ensure students process those video lectures sufficiently, open questions about the types of prompts and role of students’ engagement remain. We thus conducted an online field experiment with teacher students at a German university (N = 124; 73 female, 49 male). According to the randoml
View details →DOI: 10.1186/s41239-023-00383-9 Negative / Null Result ReportOpen accessEconomic growth, development, planning
Adhisty Mohammad Khariza, Arintoko Arintoko, Suprapto Suprapto · 2020 · Eko-Regional
Small-medium enterprises (SMEs) are the main pillar of the Indonesian economy. Based on 2016’s Economic Census, most businesses in Indonesia are SMEs, while SMEs absorb the majority of the workforce. The empowerment of SMEs is one way to improve the economy. To empower the SMEs sector, the Indonesian government launched the Kredit Usaha Rakyat (KUR) since 2007. The lasts policy is the provision of the mild interest rate for KUR since 2016. The hope is that with a mild interest rate, SMEs can get affordable financing access so they can be the driving force of the economy. However, credit demand
View details →DOI: 10.20884/1.erjpe.2020.15.2.1582 Negative / Null Result ReportOpen accessBiology (General)
Somayeh Faghih, Zabihollah Zamani, Reza Fatahi et al. · 2019 · Biological Research
Abstract Background Drought is one of the main serious problems for agriculture production which its intensity is increasing in many parts of the world, hence, improving water use efficiency is a main goal for sustainable agriculture. Results Growth indices including relative shoot length growth (SL), relative stem diameter increase (SD) and relative trunk cross sectional area growth (TCSA) measured at the start and end of the season decreased by reducing the irrigation level. Chlorophyll index (CI) was decreased at 70% crop evapotranspiration, however water use efficiency (WUE), leaf and frui
View details →DOI: 10.1186/s40659-019-0252-5 Negative / Null Result ReportOpen accessBusiness
Rina Trisnawati, Nono Wibisono · 2022 · Jurnal Bisnis dan Kewirausahaan
Sumedang Regency is an area that has various types of tourist attractions but tourist visits to Sumedang fluctuate every year. One of the attractions in Sumedang is Kampung Karuhun which still needs improvement in several aspects. This study aims to identify the influence of the relationship of service quality, tourism product availability, destination image, consumer satisfaction and destination loyalty in Kampung Karuhun Sumedang. The research method used is a quantitative approach using a survey tool in the form of a questionnaire. This study collected data as many as 355 respondents. The a
View details →DOI: 10.31940/jbk.v18i3.238-247 Negative / Null Result ReportOpen accessScience
Ruihan Li, Chuankuan Wang, Chunhua Lv et al. · 2025 · Geoderma
Improvements in stocks and stability of forest soil organic carbon can be achieved through the management of tree species. Given the long lifespan of trees and their role as the keystone species in forested ecosystems, decisions regarding tree species management can have a significant impact on soil carbon balance, with effects that may persist for decades. Here, a common garden experiment involving five temperate tree species in northeast China was conducted to quantify the influence of tree species on soil carbon dynamics, including its fractions (mineral-associated organic carbon, particula
View details →DOI: 10.1016/j.geoderma.2025.117185 Negative / Null Result ReportOpen accessMedicine
Sirous Nazari pirdoosti, Vahid Valipour dehnou, Ehsan Gharamanlou · 2019 · Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām
Introduction: Transcranial direct current stimulation (tDCS) is a non-invasive technique used to modify the activity of the cortex of the brain. This form of current is capable of inducing changes in the electrical activity inside and outside of the neurons, which leads to a change in the resting membrane potential and thus improves the efficiency of the neural synapse. Therefore, the aim of this study was to investigate the effect of tDCS over motor cortex on strength and endurance performance of healthy collegiate subjects. Materials & Methods: In total, 10 young and healthy male subjects (a
Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Suwang Zheng, Tianli Fu, Jinlong Yan et al. · 2024 · Journal of NeuroEngineering and Rehabilitation
Abstract Background Temporal interference (TI) stimulation, an innovative non-invasive brain stimulation technique, has the potential to activate neurons in deep brain regions. The objective of this study was to evaluate the effects of repetitive TI stimulation targeting the lower limb motor control area (i.e., the M1 leg area) on lower limb motor function in healthy individuals, which could provide evidence for further translational application of non-invasive deep brain stimulation. Methods In this randomized, double-blinded, parallel-controlled trial, 46 healthy male adults were randomly di
View details →DOI: 10.1186/s12984-024-01336-7 Negative / Null Result ReportOpen accessAgriculture
Óscar Chichongue, Johan J. van Tol, Gert M. Ceronio et al. · 2022 · Agronomy
Sub-Saharan Africa (SSA) agriculture is characterized by dependence on erratic rainfall, inadequate conservation practices, and a decline in soil fertility resulting in low crop productivity. Therefore, conservation agriculture (CA) has been proposed as an alternative to improve soil fertility and productivity. Hence the aim was to investigate the effects of tillage systems, fertilization, and cropping patterns on selected soil chemical properties (pH, organic carbon, total nitrogen, extractable phosphorus, exchangeable cations, and cation exchange capacity) and identify which cropping pattern
View details →DOI: 10.3390/agronomy12071534 Negative / Null Result ReportOpen accessGeriatrics
Veronika Keppner, Sebastian Krumpoch, Robert Kob et al. · 2023 · BMC Geriatrics
Abstract Background The risk of older adults being injured or killed in a bicycle accident increases significantly due to the age-related decline of physical function. Therefore, targeted interventions for older adults to improve safe cycling competence (CC) are urgently needed. Methods The “Safer Cycling in Older Age” (SiFAr) randomized controlled trial investigated if a progressive multi-component training program related to cycling improves CC of older adults. Between June 2020 and May 2022, 127 community-dwelling persons living in the area Nürnberg-Fürth-Erlangen, Germany aged 65 years and
View details →DOI: 10.1186/s12877-023-03816-2 Negative / Null Result ReportOpen accessEducation (General)
Rahmah Johar, Rahmah Johar, M. Ikhsan et al. · 2025 · Frontiers in Education
Mathematical communication skills are essential for helping students grasp mathematical concepts. Fostering students’ knowledge of Islamic values can also encourage them to relate mathematical topics to real-world situations, particularly in worship, enhancing their mathematical communication. Therefore, an innovative teaching approach is crucial to improving students’ mathematical communication and understanding of Islamic values. This study investigates the integration of these concepts within mathematics through the contextualized framework of Qurban. The study explores how an interactive w
View details →DOI: 10.3389/feduc.2025.1633056 Negative / Null Result ReportOpen accessMedicine (General)
Vinod Babu .K, Akshata Akalwadi, Sai Kumar .N et al. · 2015 · International Journal of Physiotherapy
Background: Acupuncture TENS is used to improve pain instead of invasive acupuncture. Acupuncture shown to improve dyspnoea and lung functions in COPD (Chronic Obstructive Pulmonary Disease) patients. The purpose of the study is to determine Short term effectiveness of Acupuncture-TENS in reducing dyspnea and improving lung functions for subjects with moderate COPD. Method: An experimental study design, selected 30 geriatric subjects with COPD randomized 15 subjects into each Study and Control group. Study group received Acu-TENS for 45 minutes for total 5 sessions, while control group receive
View details →DOI: 10.15621/ijphy/2015/v2i5/78246 Negative / Null Result ReportOpen accessMedical physics. Medical radiology. Nuclear medicine
Armin D. Tavakkoli, BA, Megan A. Clark, BE, Alireza Kheirollah, PhD et al. · 2024 · Advances in Radiation Oncology
Purpose: Ultra High Dose-Rate (UHDR) radiation has been reported to spare normal tissue, compared with Conventional Dose-Rate (CDR) radiation. However, important work remains to be done to improve the reproducibility of the FLASH effect. A better understanding of the biologic factors that modulate the FLASH effect may shed light on the mechanism of FLASH sparing. Here, we evaluated whether sex and/or the use of 100% oxygen as a carrier gas during irradiation contribute to the variability of the FLASH effect. Methods and Materials: C57BL/6 mice (24 male, 24 female) were anesthetized using isofl
View details →DOI: 10.1016/j.adro.2024.101492 Negative / Null Result ReportOpen accessGeriatrics
Inderpal Singh, Chris Edwards, Anser Anwar · 2018 · Geriatrics
Single-room ward design has previously been associated with increased risk of inpatient falls and adverse outcomes. However, following quality initiatives, the incidence of inpatient falls has shown a sustained reduction. Benefits have also been observed in the reduction of hip fractures. However, one-year mortality trends have not been reported. The aim of this observational study is to report the trends in one-year mortality rates before and after implementing quality-improvement initiatives to prevent inpatient falls over the last 5 years (2012–2016). This retrospective observational study
View details →DOI: 10.3390/geriatrics3010009 Negative / Null Result ReportOpen accessMedicine
Lin C, Mei YM, Yan Y et al. · 2026 · Head & face medicine
AIM: To evaluate the adjunctive clinical efficacy of manual root planing following ultrasonic subgingival debridement (SD) in the treatment of generalized severe periodontitis. MATERIAL AND METHODS: Twenty-nine patients diagnosed with…
View details →DOI: 10.1186/s13005-026-00622-0 Negative / Null Result ReportOpen accessPharmacy and materia medica
Comfort Nanbam Sariem, Maxwell Patrick Dapar, Nenman Musa Lenka et al. · 2022 · INNOVATIONS in Pharmacy
Background: The prolonged multi-drug treatment regimen for tuberculosis (TB) can lead to non-adherence and unsuccessful treatment outcomes. Educational and psychological health models can be used to design cognitive and behavioral interventions to improve adherence and treatment outcomes. Objective: To determine the effect of cognitive and behavioral interventions on TB treatment outcomes. Methods: The quasi-experimental study conducted in six TB treatment centers involved reinforced medication education and adherence counseling (MEAC), designed from a structured validated psychometric scale.
View details →DOI: 10.24926/iip.v13i4.5031 Negative / Null Result ReportOpen accessDiseases of the blood and blood-forming organs
Edvan de Queiroz Crusoe, Fabiana Higashi, Maria Paula Nalesso Camargo Padilha et al. · 2014 · Revista Brasileira de Hematologia e Hemoterapia
Background: Induction therapy followed by high-dose chemotherapy and autologous transplantation is the standard treatment for suitable patients with multiple myeloma. Objective: The aim of this study was to assess whether induction therapy with thalidomidecontaining regimens was associated with improved results compared to vincristine, doxorubicin, and dexamethasone, and whether cyclophosphamide, thalidomide, and dexamethasone were associated with better results than thalidomide and dexamethasone. Methods: The records of 152 patients who underwent autologous transplantation at this institution
View details →DOI: 10.5581/1516-8484.20140008 Negative / Null Result ReportOpen accessSurgery
Eiji Nomura, Takatoshi Seki, Kentaro Yatabe et al. · 2024 · World Journal of Surgical Oncology
Abstract Background Elderly gastric cancer patients (EGCPs) require treatment according to not just the stage of their cancer, but also to their general condition and organ function, and rather than full treatment, the appropriate amount of treatment is necessary. Methods A total of 425 patients who underwent gastrectomy for primary gastric cancer in our institution between April 2013 and March 2020 were classified by age into two groups: elderly patients (EP, age ≥ 80 years, n = 89); and younger patients (YP, age < 80 years, n = 336). The preoperative, intraoperative, and postoperative condit
View details →DOI: 10.1186/s12957-024-03488-1 Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Olga Maria Nardone, Giulio Calabrese, Alessia La Mantia et al. · 2025 · Therapeutic Advances in Gastroenterology
Background: Managing extraintestinal manifestations (EIMs) in inflammatory bowel disease (IBD) patients remains challenging due to considerable heterogeneity in diagnostic criteria and the lack of a standardised definition and validated diagnostic pathways. Delays in recognising and treating EIMs can lead to significant disease progression. Therefore, early detection and treatment are crucial. Objectives: We aimed to assess the effectiveness of a dedicated immune-mediated inflammatory diseases (IMIDs) clinic in reducing EIM diagnostic delays and improving patients’ outcomes. Design: A single-c
View details →DOI: 10.1177/17562848251323529 Negative / Null Result ReportOpen accessPlant culture
Qing Zhou, Qing Zhou, Qing Zhou et al. · 2020 · Frontiers in Plant Science
Triploid breeding is a central way to improve growth traits, timber quality, and stress resistance in Populus. In the present study, the morphology and viability of colchicine-induced 2n pollen, triploid production by crossing induced 2n pollen, and identification of genetic constitution of colchicine-induced 2n pollen were conducted in Populus canescens based on optimizing technology for inducing chromosome doubling in pollen. We found that the meiotic stage, injection time, and the interaction between the meiotic stage and injection time had highly significant effects on the 2n pollen produc
View details →DOI: 10.3389/fpls.2020.00295 Negative / Null Result ReportOpen accessOrthopedic surgery
Michał Maciejewski, Piotr Janusz, Michalina Dudkiewicz et al. · 2023 · Chirurgia Narządów Ruchu i Ortopedia Polska
Introduction. Radial neck fractures in children are rare and account for 1-3% of all childhood trauma. Severe displacement of the fracture can lead to a higher incidence of complications, such as limited range of motion (ROM), pain, instability, neurovascular trauma, premature physeal closure, cubitus valgus, radial head overgrowth, avascular necrosis and improper ossification. The treatment outcome depends on the injury type, treatment method and presence of complications.Aim. The purpose of the study was to assess the outcome of patients treated with elastic-stable intramedullary nailing (ES
View details →DOI: 10.31139/chnriop.2023.88.3.4 Negative / Null Result ReportOpen accessMedicine
Gerda Trutnovsky, MD, Brigitte Bliem, MD, Elfriede Greimel, PhD et al. · 2021 · Sexual Medicine
ABSTRACT: Introduction: Treatment for vulvodynia is challenging and a multidisciplinary approach is recommended. Aim: To examine the effectiveness, safety and treatment satisfaction of vulvovaginal microablative laser treatment for vulvodynia. Methods: Case study of women who received laser treatment as part of a multidisciplinary treatment program for vulvodynia. Subjective improvement was compared to a retrospective cohort of women treated for vulvodynia without LASER therapy. LASER treatment was offered to women with vulvodynia presenting to a gynecologic pain clinic of a tertiary universit
View details →DOI: 10.1016/j.esxm.2021.100432 Negative / Null Result ReportOpen accessSurgery
Samah Abdelfatah Eshiaty, Shimaa Abdelsattar, Dina Sweed et al. · 2023 · Egyptian Liver Journal
Abstract Background Early detection of biliary atresia (BA) is a great challenge providing the main useful way to improve its clinical consequence. Promising metabolomics provides an effective method for determining innovative biomarkers and biochemical ways for improving early diagnosis. This study aimed to determine the benefit of serum and urinary potential bile acid metabolites in the differentiation of BA from non-biliary atresia (non-BA) cases using tandem mass spectrometry (MS/MS). Fourteen bile acids metabolites were measured quantitively by MS/MS in serum and urine samples from 102 ch
View details →DOI: 10.1186/s43066-023-00244-0 Negative / Null Result ReportOpen accessMedicine
Ning Li, Jincai Huang, Yanghe Feng · 2020 · PLoS ONE
Background Cognitive ability refers to the ability to receive, process, store, and extract information. It is the most important psychological condition for people to successfully complete activities. Previous studies have shown that the design of the human-computer interface of the command and control system cannot exceed the cognitive ability of the operator of the command and control system, and it must match the cognitive ability of the operator in order to reduce the mental load intensity, and improve the accuracy, timeliness and work efficiency. However, previous researchers in the field
View details →DOI: 10.1371/journal.pone.0237339 Negative / Null Result ReportOpen accessScience
Hans IJzerman, Jaap J. A. Denissen · 2019 · Royal Society Open Science
We report a replication and extension of a finding from Studies 1 and 2 of Van Lange et al.'s influential paper (Van Lange et al. 1997 J. Pers. Soc. Psychol. 73, 733–746. (doi:10.1037/0022-3514.73.4.733)), which showed an association between Social Value Orientation (SVO) and attachment security. We report a close replication but with measures of attachment that are considered superior in comparison to measures used by Van Lange et al., due to subsequent psychometric improvements. Psychometric analyses indeed showed that our attachment measures were reliable and valid, demonstrating theoretica
View details →DOI: 10.1098/rsos.181575 Negative / Null Result ReportOpen accessMedicine (General)
Martins MJ, Martins CPMO, Castro-Alves LJ et al. · 2018 · Journal of Pain Research
Marcelo J Martins,1 Caroline Paiva Matos Oliveira Martins,2 Lucas J Castro-Alves,3 Gabriel Nascimento Jesus,4 Guilherme Oliveira Campos,5 Breno Barbosa Cerqueira Sacramento,4 Leonardo Ferrari Borges,6 Carlos Augusto Bastos Mello,6 Rodrigo Leal Alves,5 Norma Sueli Pinheiro Módolo7 1Department of Anesthesiology, São Paulo State University (UNESP), São Paulo, Brazil; 2Department of Anesthesiology at Federal University of Bahia, Bahia, Brazil; 3Department of Anesthesiology, Santo Antonio Hospital, Salvador, Bahia, Brazil; 4Department of Anesthesia, Bahia University of Medicine
Negative / Null Result ReportOpen accessMedicine (General)
Madeleine M. Southey, Trent Rees, Margaret Rolfe et al. · 2019 · Addiction Science & Clinical Practice
Abstract Background Residential opioid rehabilitation aims to improve the mental health and quality of life of opioid users through abstinence and residential program participation. This study aimed to determine the depression, anxiety, stress and quality of life amongst maintenance to abstinence (MTA) program residents. Secondary study aims were to assess the personal characteristics of MTA clients, addiction and risk taking behaviours, factors associated with program completion, as well as to assess the reliable change in participants’ mental health and quality of life on exit. Methods Retro
View details →DOI: 10.1186/s13722-019-0132-x Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Dan Zhu, Zhenzhen Fan, Fujun Cheng et al. · 2022 · Brain Sciences
Objectives: To investigate the efficacy and safety of an improved ultrasound-guided pulsed radiofrequency (PRF) and nerve block (NB) for patients with pudendal neuralgia (PN). Methods: This retrospective analysis included 88 adults with PN treated in the Pain Department of Southwest Hospital from November 2011 to June 2021, with treatment including NB ( n = 40) and PRF ( n = 48). The primary outcome variable was pain severity, measured by a standardized visual analog scale (VAS). VAS values were collected at 1, 3, 7, and 14 days and 1 and 3 months after patients were treated with NB or PRF. Re
View details →DOI: 10.3390/brainsci12040510 