Abandoned HypothesisMedicine
McNamara ME, Becker MS, Nota JA et al. · 2026 · Journal of anxiety disorders
While rumination has been recognized in clinical settings as prevalent and problematic for individuals with obsessive compulsive disorder (OCD), its relationship to OCD symptom trajectories has been understudied. In a large sample of N =…
View details →DOI: 10.1016/j.janxdis.2026.103170 Negative / Null Result ReportMedicine
Abdelnaby EA, Alhaider AK, Emam IA · 2026 · Reproduction in domestic animals = Zuchthygiene
This current work aimed to determine the impacts of melatonin implants on testicular artery blood flow and Doppler indices, in relation to hormonal profile in post-pubertal camels (Camelus dromedaries) under heat stress and non-breeding…
View details →DOI: 10.1111/rda.70180 Negative / Null Result ReportMedicine
Elad B, Lotan D, Richter I et al. · 2026 · Journal of cardiovascular pharmacology
Abstract Vericiguat improves outcomes in heart failure (HF) by promoting vasodilation of the systemic and pulmonary arterial beds. Little is known about its impact on pulmonary artery pressure (PAP). We aimed to study this effect using…
View details →DOI: 10.1097/fjc.0000000000001761 Negative / Null Result Report
Ritter C, Hausman H, Gaschler R et al. · 2025 · Preprint
Making judgments of learning (JOLs) can directly affect learning outcomes. The present study investigated whether providing JOLs during inductive learning tasks improves learning of new material (forward effect) and whether feedback…
View details →DOI: 10.31234/osf.io/vsepy_v2 Negative / Null Result ReportMedicine
Jaramillo Quiceno GA, Sarmiento Riveros PA, Arias Perez RD et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine
Introduction/objectives Residual rotational laxity remains a relevant clinical concern after anterior cruciate ligament (ACL) reconstruction. Combined ACL and anterolateral ligament (ALL) reconstruction has been proposed to improve control…
View details →DOI: 10.1016/j.jisako.2026.101073 Negative / Null Result ReportMedicine
Gonzalez W, Riquelme JP, Arellano J et al. · 2026 · BMC musculoskeletal disorders
Background Unicompartmental knee arthroplasty (UKA) is an established procedure for selected patients with unicompartmental osteoarthritis. Robotic-assisted UKA (RA-UKA) has been introduced to improve accuracy of implant positioning.…
View details →DOI: 10.1186/s12891-026-09928-1 Negative / Null Result ReportMedicine
Kijkuokool P, Rerkasem K, Fakfum P et al. · 2026 · Antioxidants (Basel, Switzerland)
Watercress ( Nasturtium officinale R.Br.) is a cruciferous vegetable rich in bioactive compounds that may improve cardiovascular disease (CVD) risk factors. However, clinical evidence regarding its direct impact on CVD risk remains…
View details →DOI: 10.3390/antiox15060766 Negative / Null Result ReportMedicine
Goyal A, Konieczny K, Plombon S et al. · 2026 · Journal of general internal medicine
Background Diagnostic errors (DEs) are a major threat to hospital patient safety. Identifying admission-based predictors associated with harmful DEs may help improve diagnostic safety in high-risk populations. Objective To assess the…
View details →DOI: 10.1007/s11606-026-10527-y Negative / Null Result ReportMedicine
Erken AA, Dincer ST · 2026 · Asia-Pacific journal of clinical oncology
Aim Total neoadjuvant therapy has been adopted to improve systemic disease control in locally advanced rectal cancer, yet long-term real-world outcomes, particularly in non-Western populations, remain incompletely defined. We compared…
View details →DOI: 10.1111/ajco.70118 Negative / Null Result ReportMedicine
Whiteside SPH, Gloe LM, Biggs BK · 2026 · Journal of clinical psychology
Objectives Cognitive behavioral therapy (CBT) is the most researched treatment for childhood anxiety disorders (CADs). Improving outcomes and efficiency of CBT will require identifying and optimizing the most efficacious therapeutic…
View details →DOI: 10.1002/jclp.70140 Negative / Null Result ReportMedicine
Virkkunen V, Kero K, Stenholm S et al. · 2026 · Menopause (New York, N.Y.)
Objectives For many women, retirement represents a significant transition in late adulthood, which may result in many alterations in lifestyle habits and behavioral patterns. Several factors known to improve during the retirement…
View details →DOI: 10.1097/gme.0000000000002778 Negative / Null Result ReportMedicine
Shirane K, Kitagawa N, Morishima R et al. · 2026 · Journal of pediatric surgery
Background Pulmonary metastasectomy can improve the survival of children with pulmonary metastases from solid tumors. However, preoperative imaging often suggests chest wall and/or mediastinal invasion, raising concerns about…
View details →DOI: 10.1016/j.jpedsurg.2026.163183 Negative / Null Result ReportMedicine
Lovern A, Watson M, Hollis A et al. · 2026 · AANA journal
Resident registered nurse anesthetists (RRNAs) face high levels of depression, anxiety, and stress (DAS) due to the academic, clinical, and financial demands of graduate anesthesia education. Nature-based mindfulness, which integrates…
View details →DOI: 10.70278/aanaj/.0000001058 Negative / Null Result ReportMedicine
Aydın Güçlü Ö, Demirdöğen E, Hunutlu FÇ et al. · 2026 · BMC infectious diseases
Background Cytomegalovirus (CMV) infection is an important cause of morbidity and mortality among immunocompromised patients, particularly those with hematologic malignancies. The present study aims to evaluate the clinical features,…
View details →DOI: 10.1186/s12879-026-13708-6 Negative / Null Result ReportMedicine
Premkumar A, Arellano E, Heo KY et al. · 2026 · The Journal of arthroplasty
Background The use of short-term postoperative corticosteroid regimens has been reported to improve pain control and decrease opioid consumption following total knee arthroplasty (TKA). The purpose of this study was to evaluate the effect…
View details →DOI: 10.1016/j.arth.2026.04.076 Negative / Null Result ReportMedicine
Nicklas A, Bienger K, Rudari M et al. · 2026 · Burns : journal of the International Society for Burn Injuries
Background Split-thickness skin grafting (STSG) remains the standard for deep second-degree burns, but grafted skin often shows suboptimal biomechanical properties. The dermal substitute MatriDerm® may improve elasticity, structural…
View details →DOI: 10.1016/j.burns.2026.107977 Negative / Null Result ReportMedicine
Lychagin AV, Gritsyuk AA, Elizarov MP et al. · 2026 · Journal of clinical medicine
Background: Robot-assisted total knee arthroplasty (raTKA) improves the precision of component positioning and coronal alignment restoration, but it remains uncertain whether that technical accuracy modifies the clinical effect of…
View details →DOI: 10.3390/jcm15124515 Negative / Null Result ReportMedicine
Jee J, Zhang J, Lavery JA et al. · 2026 · Cancer discovery
Real-world data suggest that SARS-CoV-2 mRNA vaccines, administered within 100 days of immune checkpoint inhibitor (ICI) treatment ("peri-ICI vaccination"), may improve ICI effectiveness through synergistic immune priming. In an…
View details →DOI: 10.1158/2159-8290.cd-26-0403 Negative / Null Result ReportMedicine
Espeche W, Minetto J, Cerri G et al. · 2026 · Hypertension research : official journal of the Japanese Society of Hypertension
Hypertensive disorders of pregnancy are a leading cause of maternal-fetal morbidity and mortality, with preeclampsia representing a major contributor to adverse outcomes. Ambulatory blood pressure monitoring (ABPM) has improved risk…
View details →DOI: 10.1038/s41440-026-02687-5 Negative / Null Result ReportMedicine
Vollam S, Roman C, Santos M et al. · 2026 · JMIR medical informatics
Background Many studies have evaluated the use of wearable monitoring systems to improve patient safety in hospital. Although some have demonstrated effects on intensive care admissions, there remains little evidence of impact on patient…
View details →DOI: 10.2196/81304 Negative / Null Result ReportMedicine
Mohy N, Sanaie S, Rahnemayan S et al. · 2026 · Beneficial microbes
Oxidative stress is a significant contributor to neuronal damage in multiple sclerosis (MS), marked by an imbalance in reactive oxygen species and antioxidant defences. Probiotics may modulate oxidative stress and improve antioxidant…
View details →DOI: 10.1163/18762891-bja00115 Negative / Null Result ReportMedicine
Gray SL, Liberman M, Onukwufor E et al. · 2026 · American journal of pharmaceutical education
Objectives Ageism remains a pervasive barrier to delivering high-quality health care to older adults. The objective of this scoping review is to describe studies on educational interventions aimed at improving the empathy and attitudes of…
View details →DOI: 10.1016/j.ajpe.2026.101960 Negative / Null Result ReportMedicine
Ishiguro S, Guitard D, Saint-Aubin J · 2025 · Quarterly journal of experimental psychology (2006)
Semantic relatedness of items improves working memory performance. We targeted one type of semantic relatedness, semantic association. The beneficial effect of association is often explained by the spreading-activation process:…
View details →DOI: 10.1177/17470218251392562 Failed Experiment ReportMedicine
Looman MI, Klau MM, Schoenmakers TM et al. · 2026 · Journal of sleep research
While time in bed restriction is a core treatment mechanism of Sleep Restriction Therapy (SRT), empirical research has not yielded a relationship between insomnia improvement and adherence to the prescribed time in bed. We coin this…
View details →DOI: 10.1111/jsr.70339 Negative / Null Result ReportMedicine
Daniel F, El Kouzi Z, Mrad J et al. · 2025 · Updates in surgery
Preoperative use of biologics has been inconsistently reported to be associated with increased frequency of infectious and surgical anastomotic complications in inflammatory bowel disease patients. We aimed to evaluate the rates of 30-day…
View details →DOI: 10.1007/s13304-025-02238-6 Negative / Null Result ReportMedicine
Berger M, Bruggisser F, Schwarz A et al. · 2025 · Physiology & behavior
Objectives To investigate whether a single session of aerobic exercise improves inhibitory control in preadolescent children and whether this effect is mediated by changes in parasympathetic activity. Design In this experimental study, an…
View details →DOI: 10.1016/j.physbeh.2025.114820 Negative / Null Result ReportMedicine
Stark BC, Alexander JM, Stockrahm E et al. · 2026 · American journal of speech-language pathology
Purpose This study examined the role of inner speech-defined here as the subjective experience of covert lexical access-in naming recovery following semantic feature analysis (SFA) treatment in individuals with aphasia. Specifically, it…
View details →DOI: 10.1044/2026_ajslp-25-00363 Negative / Null Result ReportMedicine
Bandura A, Mierzejewska M, Cytawa W et al. · 2026 · Cancers
Background: Oligometastatic non-small cell lung cancer (OMD NSCLC) represents a distinct clinical state with limited metastatic spread, where local ablative therapies (LAT) combined with systemic treatment may improve outcomes. Accurate…
View details →DOI: 10.3390/cancers18121880 Negative / Null Result ReportMedicine
Burton M, Haft S, Fiskeaux M et al. · 2026 · Journal of anxiety disorders
Background Prolonged Exposure (PE) is an effective treatment for PTSD and clarification of mechanisms of change can inform training and continued improvements. Posttraumatic cognitions have been shown to predict subsequent symptom change…
View details →DOI: 10.1016/j.janxdis.2026.103186 Negative / Null Result Report
Sato T · 2025 · Preprint
Objectives: The Eight-chop technique is a mechanically based nuclear segmentation method designed to improve surgical efficiency and reduce intraocular tissue stress during phacoemulsi-fication. Early postoperative aqueous flare serves as…
View details →DOI: 10.20944/preprints202512.0021.v1 