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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

1894 results for "Mpro" · page 15 of 64

Negative / Null Result Report

Union-Find Decoders For Homological Product Codes

Nicolas Delfosse, Matthew B. Hastings · 2021 · Quantum

Homological product codes are a class of codes that can have improved distance while retaining relatively low stabilizer weight. We show how to build union-find decoders for these codes, using a union-find decoder for one of the codes in…

View details →DOI: 10.22331/q-2021-03-10-406Cited by 4
Negative / Null Result Report

The Addition of the Geriatric Nutritional Risk Index to the Prognostic Scoring Systems Did Not Improve Mortality Prediction in Trauma Patients in the Intensive Care Unit

Cheng-Shyuan Rau, Ching-Hua Tsai, Sheng-En Chou et al. · 2023 · Emergency Medicine International

Background. Malnutrition is prevalent among critically ill patients and has been associated with a poor prognosis. This study sought to determine whether the addition of a nutritional indicator to the various variables of prognostic…

View details →DOI: 10.1155/2023/3768646Cited by 4
Negative / Null Result Report

Fourteen weeks of β-alanine supplementation and HIIT did not improve serum BDNF concentrations and Stroop test performance

Paloma Tavares Mendonça, Yago Medeiros Dutra, Barbara M. Antunes et al. · 2025 · International Journal of Sports Medicine

Abstract This study aimed to investigate whether 14 weeks of β-alanine supplementation and high-intensity intermittent training improves brain-derived neurotrophic factor concentrations and cognitive aspects related to executive functions…

View details →DOI: 10.1055/a-2500-5556Cited by 4
Negative / Null Result Report

Early surgery within 48 hours of admission for hip fracture did not improve 1-year mortality in Japan: a single-institution cohort study

Hiroki Iida, Yasuhiko Takegami, Yoshihito Sakai et al. · 2024 · HIP International

Introduction: Early surgery for hip fracture, within 48 hours of hospital admission, is effective in reducing mortality. However, the average preoperative waiting time for hip fractures in Japan is 4.5 days and the 1-year mortality rate…

View details →DOI: 10.1177/11207000241248836Cited by 4
Negative / Null Result Report

Ovarian damage following surgery for endometriomas, 20 years later: did awareness improve the situation?

Dalila Invernici, Gianfranco Fornelli, Marco Reschini et al. · 2025 · Archives of Gynecology and Obstetrics

Abstract Background Early reports from the beginning of this century highlighted significant ovarian damage following laparoscopic stripping of endometriomas. During the last 2 decades, the raised awareness of the possible detrimental…

View details →DOI: 10.1007/s00404-025-08039-xCited by 4
Negative / Null Result Report

An implementation of Bubble Magnification did not improve the video comprehension of individuals with central vision loss

Francisco M Costela, Stephanie M Reeves, Russell L Woods · 2021 · Ophthalmic and Physiological Optics

Abstract Purpose People with central vision loss (CVL) watch television, videos and movies, but often report difficulty and have reduced video comprehension. An approach to assist viewing videos is electronic magnification of the video…

View details →DOI: 10.1111/opo.12797Cited by 4
Negative / Null Result Report

Improving continuous-flow analysis of triple oxygen isotopes in ice cores: insights from replicate measurements

Lindsey Davidge, Eric J. Steig, Andrew J. Schauer · 2022 · Atmospheric Measurement Techniques

Abstract. Stable water isotope measurements from polar ice cores provide high-resolution information about past hydrologic conditions and are therefore important for understanding earth's climate system. Routine high-resolution…

View details →DOI: 10.5194/amt-15-7337-2022Cited by 4
Negative / Null Result Report

The adoption of an electronic health record did not improve A1c values in Type 2 diabetes

Harry B Burke, Dorothy A Becher, Albert Hoang et al. · 2016 · Journal of Innovation in Health Informatics

Background: A major justification for the clinical adoption of electronic health records (EHRs) was the expectation that it would improve the quality of medical care. No longitudinal study has tested this assumption.Objective: We used…

View details →DOI: 10.14236/jhi.v23i1.144Cited by 4
Negative / Null Result Report

Hydrochar did not reduce rice paddy NH3 volatilization compared to pyrochar in a soil column experiment

Xiaoyu Liu, Yueqin Cheng, Yang Liu et al. · 2020 · Scientific Reports

Abstract Pyrochar (PC) is always with high pH value, and improper application might increase rice paddy ammonia volatilization (PAV), which is the main nitrogen loss through air during rice production. Differently, hydrochar (HC) takes the…

View details →DOI: 10.1038/s41598-020-76213-zCited by 3
Negative / Null Result Report

Virtual Reality-Assisted, Single-Session Exposure for Public Speaking Anxiety: Improved Self-Reports and Heart Rate but No Significant Change in Heart Rate Variability

Tonia-Flery Artemi, Thekla Konstantinou, Stephany Naziri et al. · 2025 · Virtual Worlds

Introduction: This study examines the combined use of objective physiological measures (heart rate [HR], heart rate variability [HRV]) and subjective self-reports to gain a comprehensive understanding of anxiety reduction…

View details →DOI: 10.3390/virtualworlds4020027Cited by 3
Negative / Null Result Report

Addition of an online, validated family history questionnaire to the Dutch FIT-based screening programme did not improve its diagnostic yield

Victorine H. Roos, Frank G. J. Kallenberg, Manon van der Vlugt et al. · 2020 · British Journal of Cancer

Abstract Background Faecal immunochemical testing (FIT) is suboptimal in detecting advanced neoplasia (AN). To increase the sensitivity and yield of a FIT-based screening programme, FIT could be combined with risk factors for AN. We…

View details →DOI: 10.1038/s41416-020-0832-8Cited by 3
Negative / Null Result Report

Did the accuracy of oral amoxicillin dosing of children improve after British National Formulary dose revisions in 2014? National cross-sectional survey in England

Olivia Rann, Mike Sharland, Paul Long et al. · 2017 · BMJ Open

Objectives Inaccurate antibiotic dosing can lead to treatment failure, fuel antimicrobial resistance and increase side effects. The British National Formulary for Children (BNFC) guidance recommends oral antibiotic dosing according to age…

View details →DOI: 10.1136/bmjopen-2017-016363Cited by 3
Negative / Null Result Report

Increased recurrent risk did not improve cerebrovascular disease survivors’ response to stroke in China: a cross-sectional, community-based study

Shengde Li, Li-Ying Cui, Craig Anderson et al. · 2020 · BMC Neurology

Abstract Background Cerebrovascular disease (CVD) survivors are at a high risk of recurrent stroke. Although it is thought that survivors with higher risk of stroke respond better to stroke onset, to date, no study has been able to…

View details →DOI: 10.1186/s12883-020-01724-1Cited by 3
Negative / Null Result Report

Strategically creating maximally heterogeneous lab groups did not improve group performance in an introductory biology lab class

Anisha S. Navlekar, Elli J. Theobald, Ken Griffith et al. · 2025 · PLOS One

Collaboration is a critical skill for professionals in any field to master, and group work is a prominent component of many lab courses. However, there is conflicting guidance about the best method for forming groups to maximize…

View details →DOI: 10.1371/journal.pone.0323799Cited by 3
Negative / Null Result Report

Preoperative walking intervention did not appear to improve patient-reported postoperative recovery in older adults with frailty traits: Randomized trial

Hammad Sadiq, Sanjeev Rampam, Jay Patel et al. · 2022 · Medicine

Objectives: To assess the impact of a preoperative walking intervention on improving postoperative recovery in at-risk frail older adult patients. Study Type: Unblinded, randomized controlled trial which assigned patients to intervention…

View details →DOI: 10.1097/md.0000000000030689Cited by 3
Negative / Null Result Report

Beaver dam analogs did not improve beaver translocation outcomes in a desert river

Christine Sandbach, Julie K. Young, Mary Conner et al. · 2024 · Restoration Ecology

Stream restoration programs employ beaver‐related restoration techniques, including beaver translocations and installation of beaver dam analogs (BDA), to create complex in‐stream habitat. We investigated whether BDA installations improved…

View details →DOI: 10.1111/rec.14107Cited by 3
Negative / Null Result Report

Did the ERAS Protocol Improve Our Results in Locally Advanced Gastric Cancer Surgery?

Özgül Düzgün, Pırıltı Özcan, Mehmet Faik Özçelik · 2022 · Journal of Personalized Medicine

ERAS is a protocol consisting of multidisciplinary approaches, including patient education, fluid resuscitation, keeping patients’ innormothermic state, early feeding, and mobilization. We aimed to present and compare the postoperative…

View details →DOI: 10.3390/jpm12101549Cited by 3
Negative / Null Result Report

Fellow Efficiency During Anterior Cruciate Ligament Reconstruction Improves Over Time, Yet Is Less Than Experienced Physician Assistant But With No Significant Difference in Patient‐Reported Outcomes

Sean M. Hazzard, Donna M. Scarborough, Eric M. Berkson et al. · 2022 · Arthroscopy, Sports Medicine, and Rehabilitation

Purpose To evaluate the intraoperative efficiency and patient outcomes of anterior cruciate ligament reconstruction (ACLR) assisted by a sports medicine fellow over the course of the academic year compared with an experienced physician…

View details →DOI: 10.1016/j.asmr.2022.11.011Cited by 3
Negative / Null Result Report

Degenerative lumbar changes have a statistically significant but small effect on trabecular bone score (TBS)-adjusted fracture risk (FRAX)

Malik E. Juweid, Dana Alselaibi, Hiba Abandeh et al. · 2023 · Medicine

Trabecular bone score (TBS) assesses trabecular microarchitecture at the lumbar spine and was shown to improve fracture risk prediction compared to bone mineral density (BMD) alone. We investigated whether lumbar degenerative changes (DC)…

View details →DOI: 10.1097/md.0000000000036082Cited by 2
Negative / Null Result Report

Patients Undergoing Elective Inpatient Major Therapeutic Procedures in Florida Had No Significant Change in Hospital Mortality or Mortality-Related Comorbidities Between 2007 and 2019

Richard H. Epstein, Franklin Dexter, Brenda G. Fahy · 2023 · Anesthesia & Analgesia

BACKGROUND: In a recent study, rapid response team implementation at 1 hospital was associated with only a 0.1% reduction in inpatient mortality from 2005 to 2018, characterized in the accompanying editorial as a “tepid” improvement. The…

View details →DOI: 10.1213/ane.0000000000006494Cited by 2
Negative / Null Result Report

Identification of Most Significant Parameter of Impact of Climate Change and Urbanization on Operational Efficiency of Hydropower Plant

Priyanka Majumder, Apu Kumar Saha · 2019 · International Journal of Energy Optimization and Engineering

The operational performance of hydropower plants (HPPs) is largely affected as the output from the plant entirely depends on the rainfall and demand from consumers both of which are compromised due to the vulnerability in climatic patterns…

View details →DOI: 10.4018/ijeoe.2019070103Cited by 2
Negative / Null Result Report

Humans outperform Merlin Sound ID in field-based point-count surveys

Brooke D Goodman, Kyle A Lima, Seth Benz et al. · 2025 · Ornithological Applications

Abstract Point counts are integral to bird population monitoring, and multiple methods have been developed to improve their reliability. These methods include multiple-observer protocols, double-sampling, and surveys using autonomous…

View details →DOI: 10.1093/ornithapp/duaf049Cited by 2
Negative / Null Result Report

Conventional machine learning-based prediction models did not outperform the International IgA Nephropathy Prediction Tool

Sehoon Park, Yisak Kim, Chung Hee Baek et al. · 2025 · Kidney Research and Clinical Practice

Background: Immunoglobulin A nephropathy (IgAN) is a major cause of end-stage kidney disease (ESKD). The International IgA Nephropathy Prediction Tool (IIgAN-PT) predicts IgAN prognosis, but improvement in the prediction performance using…

View details →DOI: 10.23876/j.krcp.23.212Cited by 2
Negative / Null Result Report

A single session of a beach volleyball exergame did not improve state anxiety level in healthy adult women

Vinnycius Nunes de Oliveira, Ricardo Borges Viana, João Victor Rosa de Freitas et al. · 2024 · BMC Sports Science, Medicine and Rehabilitation

Abstract This study evaluated the acute effect of the exergame Kinect Sports ® beach volleyball on state anxiety level in adult women. Thirty healthy adult women (age: 21 [4] years, body mass: 54.70 [19.50] kg, height: 1.61 ± 0.05 m, and…

View details →DOI: 10.1186/s13102-024-00859-9Cited by 2