Negative / Null Result Report
Olive Lennon, Deirdre Phelan, Deborah Wallace et al. · 2019 · Physiotherapy Research International
Abstract Background and Purpose Evidence‐based practice (EBP), which integrates clinical reasoning skills, research evidence, and patient preference, has become standard in curricula for health care professional programs. Students however…
View details →DOI: 10.1002/pri.1774Cited by 15 Negative / Null Result ReportOpen accessMedicine
В. Т. Ивашкин, М. V. Maevskaya, Е. Н. Широкова et al. · 2021 · Drugs - Real World Outcomes
While no “gold-standard” pharmacotherapy for nonalcoholic fatty liver disease (NAFLD) is yet established, essential phospholipids (EPLs) are reported to decrease steatosis and improve laboratory parameters. This analysis evaluated…
View details →DOI: 10.1007/s40801-021-00250-xCited by 15 Negative / Null Result ReportOpen accessNeuroscience
Brian Premchand, Liyuan Liang, Kok Soon Phua et al. · 2024 · NeuroSci
Detecting stress is important for improving human health and potential, because moderate levels of stress may motivate people towards better performance at cognitive tasks, while chronic stress exposure causes impaired performance and health risks. We propose a Brain-Computer Interface (BCI) system to detect stress in the context of high-pressure work environments. The BCI system includes an electroencephalogram (EEG) headband with dry electrodes and an electrocardiogram (ECG) chest belt. We collected EEG and ECG data from 40 participants during two stressful cognitive tasks: the Cognitive Vig
View details →DOI: 10.3390/neurosci5040031Cited by 15 Negative / Null Result ReportOpen accessMedicine
Harold E. Lebovitz, Bernhard Ludvik, Jarosław Kozakowski et al. · 2015 · Physiological Reports
Gastric electrical stimulation with the implanted DIAMOND device has been shown to improve glycemic control and decrease weight and systolic blood pressure in patients with type 2 diabetes inadequately controlled with oral antidiabetic agents. The objective of this study was to determine if device implantation alone (placebo effect) contributes to the long-term metabolic benefits of DIAMOND(®) meal-mediated gastric electrical stimulation in patients with type 2 diabetes. The study was a 48 week randomized, blinded, cross-over trial in university centers comparing glycemic improvement of DIAMON
View details →DOI: 10.14814/phy2.12456Cited by 15 Negative / Null Result ReportOpen accessMedicine
Megan Duffy, Christie Anderson, Kevin Choy et al. · 2018 · PubMed
= 0.84), at 184 +/- 17 days for patients which received ML, and 154 +/- 20 days for those which did not. Metronomic lomustine administration was well-tolerated, but it did not improve survival in dogs with palliatively treated osteosarcoma.
Negative / Null Result Report
Charlie Curtsinger, Emery D. Berger · 2013 · ACM SIGARCH Computer Architecture News
Researchers and software developers require effective performance evaluation. Researchers must evaluate optimizations or measure overhead. Software developers use automatic performance regression tests to discover when changes improve or…
View details →DOI: 10.1145/2490301.2451141Cited by 15 Negative / Null Result Report
Goran Rondovic, Dragan Djordjevic, Ivo Udovicic et al. · 2022 · Biomedicines
Complex immune response to infection has been highlighted, more than ever, during the COVID-19 pandemic. This review explores the immunomodulatory treatment of moderate-to-severe forms of this viral sepsis in the context of specific…
View details →DOI: 10.3390/biomedicines10102620Cited by 14 Negative / Null Result Report
Andrew Street, Laia Maynou, Simon Conroy · 2023 · BMJ Quality & Safety
Objectives To evaluate whether the Acute Frailty Network (AFN) was more effective than usual practice in supporting older people living with frailty to return home from hospital sooner and healthier. Design Staggered…
View details →DOI: 10.1136/bmjqs-2022-015832Cited by 14 Negative / Null Result ReportOpen accessNeuroscience
Charlotte Seijger, Joost Raaphorst, Judith M. Vonk et al. · 2021 · Respiration
BACKGROUND: Non-invasive home mechanical ventilation (HMV) is a complex treatment in myotonic dystrophy type 1 (DM1) patients, due to a presumed poor adherence, variable symptom improvement, and uncertainty regarding survival benefits.…
View details →DOI: 10.1159/000511962Cited by 14 Failed Experiment ReportOpen accessBiochemistry, Genetics and Molecular Biology
Deanna Schmitt, Dawn M. O’Dee, Joseph Horzempa et al. · 2012 · PLoS ONE
Vaccination is a proven strategy to mitigate morbidity and mortality of infectious diseases. The methodology of identifying and testing new vaccine candidates could be improved with rational design and in vitro testing prior to animal experimentation. The tularemia vaccine, Francisella tularensis live vaccine strain (LVS), does not elicit complete protection against lethal challenge with a virulent type A Francisella strain. One factor that may contribute to this poor performance is limited stimulation of antigen-presenting cells. In this study, we examined whether the interaction of genetical
View details →DOI: 10.1371/journal.pone.0031172Cited by 14 Negative / Null Result ReportAgricultural and Biological Sciences
Aaron S. Weed · 2010 · Entomologia Experimentalis et Applicata
Abstract Several studies have shown that group feeding by immature insects enhances larval performance through feeding facilitation. However, the benefits of this behavior have not been studied for species that hatch off from their host…
View details →DOI: 10.1111/j.1570-7458.2010.01057.xCited by 14 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Manuel A. Silva, Anderson Veronese, Anna Luiza Belli et al. · 2021 · Journal of Dairy Science
kg) than cows diagnosed with a clinical disease that had an AMD alert. Adding AMD-generated health alerts to the health screening of postpartum cows in a herd with an existing screening program did not improve survival, milk yield, or…
View details →DOI: 10.3168/jds.2020-18562Cited by 14 Negative / Null Result Report
Travis A. Smith, Eliza M. Mojduszka, Shun Chen · 2020 · Applied Economic Perspectives and Policy
Abstract School meal programs represent the second largest form of food assistance in the United States. Schools receive federal reimbursements, totaling $17 billion in 2018, provided they meet certain nutritional standards. The Healthy…
View details →DOI: 10.1002/aepp.13074Cited by 14 Negative / Null Result ReportOpen accessEngineering
Gábor Szabó, András Ágoston, Gábor Csató et al. · 2021 · Sensors
As demonstrated by earlier studies, pre-hospital triage with trans-telephonic electrocardiogram (TTECG) and direct referral for catheter therapy shows great value in the management of out-of-hospital chest pain emergencies. It does not only improve in-hospital mortality in ST-segment elevation myocardial infarction, but it has also been identified as an independent predictor of higher in-hospital survival rate. Since TTECG-facilitated triage shortens both transport time and percutaneous coronary intervention (PCI)-related procedural time intervals, it was hypothesized that even high-risk patie
View details →DOI: 10.3390/s21030969Cited by 14 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Wil Biddle, David G. Schwark, Margaret A. Schmitt et al. · 2022 · Frontiers in Chemistry
The expansion of the genetic code beyond a single type of noncanonical amino acid (ncAA) is hindered by inefficient machinery for reassigning the meaning of sense codons. A major obstacle to using directed evolution to improve the efficiency of sense codon reassignment is that fractional sense codon reassignments lead to heterogeneous mixtures of full-length proteins with either a ncAA or a natural amino acid incorporated in response to the targeted codon. In stop codon suppression systems, missed incorporations lead to truncated proteins; improvements in activity may be inferred from increase
View details →DOI: 10.3389/fchem.2022.815788Cited by 14 Negative / Null Result ReportMedicine
Christoph Rochlitz, Roger von Moos, Martin Bigler et al. · 2014 · Journal of Clinical Oncology
518 Background: Bevacizumab combined with chemotherapy has been shown to improve response rate and PFS in metastatic breast cancer. The aim of our study was to demonstrate decreased toxicity of metronomic chemotherapy/bevacizumab when…
View details →DOI: 10.1200/jco.2014.32.15_suppl.518Cited by 14 Negative / Null Result Report
Elysia Larson, Godfrey M Mbaruku, Jessica Cohen et al. · 2019 · International Journal for Quality in Health Care
Abstract Objective To test the success of a maternal healthcare quality improvement intervention in actually improving quality. Design Cluster-randomized controlled study with implementation evaluation; we randomized 12 primary care…
View details →DOI: 10.1093/intqhc/mzz126Cited by 13 Negative / Null Result ReportOpen accessComputer Science
Rabab Ali Abumalloh, Mehrbakhsh Nilashi, Osama Halabi et al. · 2024 · Journal of Innovation & Knowledge
Recommendation agents (RAs) have proven to be effective decision-making tools for customers, as they can boost trust and loyalty when customers shop online. They can analyse large amounts of data using machine learning algorithms and…
View details →DOI: 10.1016/j.jik.2024.100569Cited by 13 Negative / Null Result ReportOpen accessEnvironmental Science
Barbara Smith, Dan Carpenter, J. M. Holland et al. · 2023 · Journal of Applied Ecology
Abstract Lowland heath is a priority habitat for conservation, nowadays largely managed for biodiversity. Historically, prescribed burning has been the principal management tool, but there are increasing calls to substitute burning with cutting to improve biodiversity outcomes. However, poor understanding of potential impacts compromises decision making. Our study was carried out in the New Forest National Park, the largest area of lowland heath in Europe. Using a multi‐trophic approach, we compared the ecological impact of prescribed burning with two types of vegetation cutting (swiping and b
View details →DOI: 10.1111/1365-2664.14471Cited by 13 Negative / Null Result ReportOpen accessMaterials Science
Malek Msheik, Sylvain Rodat, Stéphane Abanades · 2024 · Journal of Analytical and Applied Pyrolysis
Solar methane pyrolysis in different molten media and reactor configurations was experimented to improve hydrogen production . Pure Sn, Ni 0.18 Sn 0.82 , Cu 0.45 Bi 0.55 , and KCl melts were compared at three different temperatures…
View details →DOI: 10.1016/j.jaap.2024.106756Cited by 13 Methods Dead-End
Till Francke, Gabriele Baroni, Arlena Brosinsky et al. · 2018 · Water Resources Research
Abstract Modelers can improve a model by addressing the causes for the model errors (data errors and structural errors). This leads to implementing model enhancements (MEs), for example, meteorological data based on more monitoring…
View details →DOI: 10.1029/2018wr022813Cited by 13 Negative / Null Result Report
Henry W. Caplan, Karthik S. Prabhakara, Naama E. Toledano Furman et al. · 2021 · PLOS ONE
Traumatic brain injury (TBI) causes both physical disruption of the blood brain barrier (BBB) and altered immune responses that can lead to significant secondary brain injury and chronic inflammation within the central nervous system…
View details →DOI: 10.1371/journal.pone.0251601Cited by 13 Negative / Null Result Report
Mohammad Nourani, Qian Long Kweh, Wen-Min Lu et al. · 2022 · Financial Innovation
Abstract This study examines the efficiency of investment trust companies (ITCs) from 2011 to 2020 using a meta-frontier two-stage network data envelopment analysis (DEA) based on the directional distance function (DDF). We improved the…
View details →DOI: 10.1186/s40854-022-00382-1Cited by 13 Negative / Null Result ReportOpen accessPhysics and Astronomy
Chuneeta D. Nunhokee, Donald M. Null, Cathryn M. Trott et al. · 2025 · The Astrophysical Journal
Abstract This paper presents the spherically averaged 21 cm power spectrum derived from Epoch of Reionization (EoR) observations conducted with the Murchison Widefield Array (MWA). The analysis uses EoR0-field data, centered at (R.A. = 0 h , decl. = −27 ∘ ), collected between 2013 and 2023. Building on the improved methodology described in C. M. Trott et al. (2024), we incorporate additional data quality control techniques introduced in C. D. Nunhokee (2020). We report the lowest-power-level limits on the EoR power spectrum at redshifts z = 6.5, z = 6.8, and z = 7.0. These power levels, measur
View details →DOI: 10.3847/1538-4357/adda45Cited by 13 Negative / Null Result Report
S.F. Hall, R. Griffiths · 2016 · Current Oncology
Background: For oncologists and for patients, no site-specific clinical trial evidence has emerged for the use of concurrent chemotherapy with radiotherapy (ccrt) over radiotherapy (rt) alone for cancer of the hypopharynx (hpc) or for…
View details →DOI: 10.3747/co.23.3085Cited by 13 Negative / Null Result Report
Qihan Ma, Jianbo Wang, Ming Xiong et al. · 2023 · Remote Sensing
The lockdowns from the coronavirus disease of 2019 (COVID-19) have led to a reduction in anthropogenic activities and have hence reduced primary air pollutant emissions, which were reported to have helped air quality improvements. However,…
View details →DOI: 10.3390/rs15051295Cited by 13 Negative / Null Result ReportOpen accessMedicine
Daniel I. McIsaac, Susan M. Lee, Dean Fergusson et al. · 2025 · JAMA Surgery
Importance: Explanatory trials suggest that prehabilitation has efficacy in improving surgical outcomes. The effectiveness of offering home-based prehabilitation across multiple centers and for older adults with frailty remains unknown. Objective: To evaluate the effectiveness of offering coach-supported, home-based prehabilitation to older surgical patients with frailty. Design, Setting, and Participants: This study is a pragmatic, parallel-arm, multicenter randomized clinical trial with embedded qualitative assessment. Clinicians and assessors were fully blinded; participants were partially
View details →DOI: 10.1001/jamasurg.2025.5288Cited by 13 Negative / Null Result ReportOpen accessMedicine
Jan Walter Benjamins, Ming Wai Yeung, Teemu Maaniitty et al. · 2021 · International Journal of Cardiology
BACKGROUND: Standard computed tomography angiography (CTA) outputs a myriad of interrelated variables in the evaluation of suspected coronary artery disease (CAD). But an important proportion of obstructive lesions does not cause significant myocardial ischemia. Nowadays, machine learning (ML) allows integration of numerous variables through complex interdependencies that optimize classification and prediction at the individual level. We evaluated ML performance in integrating CTA and clinical variables to identify patients that demonstrate myocardial ischemia through PET and those who ultimat
View details →DOI: 10.1016/j.ijcard.2021.04.009Cited by 13 Negative / Null Result ReportMedicine
Jing Luo, Zheng Dong, Hui Xie et al. · 2022 · Liver International
BACKGROUND & AIMS: Management of elderly patients with hepatocellular carcinoma (HCC) has become a major concern. Some data suggest that cryoablation improves the outcomes of elderly patients with HCC, but its efficacy and safety remain…
View details →DOI: 10.1111/liv.15169Cited by 13 Negative / Null Result ReportOpen accessNeuroscience
Maliha Ashraf, Alexandre Chapiro, Rafał Mantiuk · 2025 · Nature Communications
As large engineering efforts go towards improving the resolution of mobile, augmented reality (AR), and virtual reality (VR) displays, it is important to know the maximum resolution at which further improvements bring no noticeable benefit. This limit is often referred to as the retinal resolution, although the limiting factor may not necessarily be attributed to the retina. To determine the ultimate resolution at which an image appears sharp to our eyes with no perceivable blur, we created an experimental setup with a sliding display, which allows for continuous control of the resolution. The
View details →DOI: 10.1038/s41467-025-64679-2Cited by 13 