Negative / Null Result ReportOpen accessPublic aspects of medicine
Tao Yi, Zi Lin, Feng Hu et al. · 2025 · BMC Public Health
Abstract Background Data for the study cohort were sourced from the National Health and Nutrition Examination Survey (1999–2018). Study participants were classified as obese (BMI ≥ 30 kg/m²) or nonobese (BMI < 30 kg/m²) then further categorized as metabolically healthy or unhealthy on the basis of metabolic syndrome criteria, resulting in four groups: metabolically healthy obese (MHO), metabolically unhealthy obese (MUO), metabolically healthy nonobese (MHNO), and metabolically unhealthy nonobese (MUNO). Complex sampling statistical methods were employed for descriptive analysis. The associati
View details →Negative / Null Result ReportOpen accessInternal medicine
Richard Lowry, Danice K. Eaton, Kathryn Foti et al. · 2012 · Journal of Obesity
Increasing attention is being focused on sleep duration as a potential modifiable risk factor associated with obesity in children and adolescents. We analyzed data from the national Youth Risk Behavior Survey to describe the association of obesity (self-report BMI ≥95th percentile) with self-reported sleep duration on an average school night, among a representative sample of US high school students. Using logistic regression to control for demographic and behavioral confounders, among female students, compared to 7 hours of sleep, both shortened (≤4 hours of sleep; adjusted odds ratio (95% con
View details →Negative / Null Result ReportOpen accessMedical emergencies. Critical care. Intensive care. First aid
Gustav Torisson, MD, PhD, Martin Bruun Madsen, MD, PhD, Agnes Schmidt Davidsen, MD et al. · 2021 · Critical Care Explorations
Objectives:. To explore the association between antibiotic combination therapy and in-hospital mortality in patients with septic shock in two tertiary ICUs in different countries. Design:. Retrospective observational study. Setting:. ICUs of two tertiary hospitals, Royal Brisbane and Women’s Hospital, Brisbane, QLD, Australia, and Rigshospitalet, Copenhagen, Denmark. Patients:. Adult patients with antibiotic treatment greater than or equal to 72 hours and vasopressor therapy greater than or equal to 24 hours. Intervention:. Combination versus mono antibiotic therapy. Measurements and Main Resu
View details →Negative / Null Result ReportOpen accessSurgery
Sandro Hügli, Philip C. Müller, Matthias Pfister et al. · 2023 · Transplantology
Background: Despite great progress in graft survival and complication rates, pronounced inflammatory responses are common after pancreas transplantation (PT). Subsequent to the first postoperative increase in inflammatory markers, we have frequently observed a second peak of C-reactive protein (CRP) and white blood cells (WBCs) following PT. This analysis is to assess the incidence and clinical relevance of late-onset increases in inflammatory markers following PT. Materials and methods: We analyzed all consecutive PTs over a 20-year period. The second peak of CRP (SCP) and WBCs (SWP) was defi
View details →Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Haohui Zhu, Jianjun Yuan, Yisa Wang et al. · 2014 · Brazilian Journal of Infectious Diseases
Objective: To evaluate whether or not highly active antiretroviral therapy is associated with carotid artery stiffness in human immunodeficiency virus-positive patients in Henan Province, China. Method: Fifty human immunodeficiency virus-positive patients with at least a 5-year history of highly active antiretroviral therapy use and 50 human immunodeficiency virus-positive patients without a history of highly active antiretroviral therapy use were enrolled in this study. Carotid artery intima-media thickness and stiffness were determined by quantitative inter-media thickness and quantitative a
View details →Negative / Null Result ReportOpen accessDentistry
Reza Pourabbas, Samin Farajzadeh, Amirreza Babaloo et al. · 2023 · Journal of Dental Research, Dental Clinics, Dental Prospects
Background. Studies have suggested a correlation between periodontitis and reduced male fertility. Inflammation has been described as the link between these ailments. Oral inflammatory load (OIL) can be measured through oral polymorphonuclear neutrophil (oPMN) count, which is associated with periodontal diseases. This cross-sectional study assessed the possible correlation between OIL and the functional parameters of sperm cells. Methods. In 229 volunteers, oral rinse and semen samples were assessed for oPMN, semen polymorphonuclears (sPMNs), sperm concentration, total sperm count, motility, m
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S. Saini, Sarita Pandey, Kanika · 2026 · Journal of Clinical and Diagnostic Research
Introduction: Rehabilitation plays a vital role in managing Parkinson’s Disease (PD), particularly in addressing both motor and cognitive impairments. Dual Task Training (DTT) improves motor symptoms and cognitive performance, while…
View details →Negative / Null Result ReportOpen accessPediatrics
Ahmed E. Abdulgalil, Noha H. Elnagdy, Nehal M. Ramadan et al. · 2025 · Pediatric Rheumatology Online Journal
Abstract Introduction Mycophenolate Mofetil (MMF) has become one of the cornerstone treatments of lupus nephritis (LN). It is converted into mycophenolic acid (MPA), an active metabolite, that displays high inter- and intra-individual pharmacokinetic variability. However, the routine monitoring of MPA trough level is still debatable. Objectives The present study aims to evaluate the relationship between MPA trough levels and both clinical outcomes and drug-related adverse effects during the maintenance phase of LN in Egyptian patients. Methods We included thirty-five adults and twenty-nine chi
View details →Negative / Null Result ReportOpen accessMedicine
Tao Li, Xiaodong Zhou, Zhi Wang et al. · 2016 · PLoS ONE
To evaluate retinal thickness (RT), retinal volume (RV) and choroidal thickness (ChT) in Chinese children using Cirrus-HD optical coherence tomography (OCT), and assess their associations with spherical equivalent (SE), age and gender.This was a prospective study that recruited 193 healthy Chinese children (193 eyes) with no ophthalmic disease history between December 2012 and December 2013. RT and RV were acquired using OCT. Subfoveal ChT (SFCT) and ChT1-mm and 2-mm temporal, nasal, superior and inferior to the fovea were measured manually.RT in the inner temporal and nasal regionsdiffered si
View details →Negative / Null Result ReportOpen accessMicrobiology
Mamta Soni, Supraja Sundaram, Sindhuja Kesavan · 2021 · National Journal of Laboratory Medicine
Introduction: Haemophagocytic Lymphohistiocytosis (HLH) is a rapidly progressive life threatening condition in which activated macrophages engulf haematopoietic cells. HLH is often overlooked because of its rarity and lack of awareness of this prevailing condition. Though previously attempts have been made to quantify hemophagocytes in marrow aspirates, to the best of present knowledge, none of the studies have correlated the number of hemophagocytes with the clinical outcomes of the patients. Aim: To study the role of laboratory parameters and number of hemophagocytes detected in bone marrow
View details →Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Paula Melariri, Chioma Ihemanma, Udoka Chigbo et al. · 2024 · Journal of Parasitology Research
Malaria presents a huge threat to pregnant women, their foetus, and children below five years. This study is aimed at assessing malaria prevalence, associated clinical symptoms, and urine abnormalities among pregnant women in Aba metropolis, Abia State, Nigeria. A cross-sectional study involving 450 pregnant women purposively selected from nine health care centres was conducted. Data were analysed using SPSS version 26. The overall malaria prevalence rate was 68.4% (n=308). Age group of 21-25 years had the highest prevalence rate of 20.4% (n=92) while the least was recorded among the age group
View details →Negative / Null Result ReportOpen accessOphthalmology
Neoh Yee Ling, Tan Ee Ling, Syed Mudassar Imran Bukhari et al. · 2015 · Journal of Clinical Ophthalmology and Research
Introduction: Systemic diseases such as hypertension and diabetes mellitus (DM) have been identified as the risk factor for glaucoma. However, there is minimal knowledge on the impact of systemic diseases on severity of glaucoma. This study aimed to determine the association between systemic disease and systemic treatment and severity of glaucoma. Materials and Methods: A cross-sectional study was conducted involving 298 primary open-angle glaucoma (POAG; 169 high tension glaucoma (HTG) and 129 normal tension glaucoma (NTG)) patients presented at the eye clinic of two tertiary hospitals in Mal
View details →Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Jian Sun, Zhiyong Shi, Lebao Yu et al. · 2022 · BMC Neurology
Abstract Objective To explore potential risk factors of preoperative cognitive dysfunction in adult patients with moyamoya disease (MMD) and discuss significance of moyamoya vessels. Methods The author reviewed adult MMD patients harboring no parenchymal infarction or hemorrhage underwent a standardized neuropsychological assessment test battery from December 2018 to May 2019. The authors defined patients with cognitive dysfunction as cognitive impairment shown on 3 or more neuropsychological tests. According to the presence of cerebral angiography, arterial stenosis, moyamoya vessels, and com
View details →Negative / Null Result ReportOpen accessNursing
Parul Sharma, Bindu Shaiju, Jahanara Rahman et al. · 2024 · Indian Journal of Psychiatric Nursing
Introduction: Nurses make up the largest group of health-care workers, so it is important to rule out compassion fatigue (CF) and compassion satisfaction among nursing officers. Methodology: A descriptive study was adopted, and purposive sampling technique was used. The present study’s sample included 134 nursing officers. The data were gathered in January 2022 using the Structured CF Scale and the Structured Compassion Satisfaction Scale. The data were analyzed using descriptive and inferential statistics. Results: The findings of the research revealed that the majority of the nursing officer
View details →Negative / Null Result ReportOpen accessMedicine (General)
Katarzyna Budzynska, Daniel Passerman, Denise White-Perkins et al. · 2018 · BMC Family Practice
Abstract Background Colorectal cancer (CRC) develops from colorectal adenomatous polyps. This study is to determine if diabetes mellitus (DM), its treatment, and hemoglobin A1c (HbA1c) level are associated with increased risk of colorectal adenomatous polyps. Methods This was a retrospective cohort study that included patients who had at least one colonoscopy and were continuously enrolled in a single managed care organization during a 10-year period (2002–2012). Of these patients (N = 11,933), 1800 were randomly selected for chart review to examine the details of colonoscopy and pathology fin
View details →Negative / Null Result ReportOpen accessPsychiatry
U. Raja, A. Misra, N. Kar · 2024 · European Psychiatry
Introduction The Crisis and Home Treatment Teams (CRHT) in psychiatry manages patients with risk to self and others in the community. The number of patents under CRHT who attempt or die of suicide is high in the UK (Hunt et al BJPsych Bull. 2016;40:172-4). The CRHT is an option to help support patients in managing their risk using various interventions and also aim to prevent admission to acute psychiatric wards where possible. Objectives We intended to study the change in risk to self and others and the factors associated with it during the intervention from a CRHT taking care of adult patien
View details →Negative / Null Result ReportOpen accessMedicine
Hoda Shamsaddin, Fatemeh Jahanimoghadam, Hamidreza Poureslami et al. · 2017 · Journal of Oral Health and Oral Epidemiology
BACKGROUND AND AIM: Early childhood caries (ECC) is a specific form of rampant dental caries affecting infants and young children. ECC is still a problem that threatens the health of the community and its management is important. It is believed that the majorities of children with ECC also suffer from malnutrition, anemia, low weight and altered physical growth patterns. This study was undertaken to compare blood indices [mean corpuscular volume (MCV), hemoglobin and serum ferritin] in a population of children in Kerman, Iran, and the association between growth factors, blood parameters, and E
View details →Negative / Null Result ReportOpen accessMedicine
Yousef Roosta, Ahmad Nazarpour, Farhad Behzadi et al. · 2025 · Disease and Diagnosis
Background: The number of individuals undergoing dialysis is rising. Impaired renal function has been linked to a heightened risk of cancer. This study aimed to examine cancer incidence among hemodialysis (HD) patients. Materials and Methods: This retrospective cross-sectional study analyzed the medical records of individuals with newly diagnosed end-stage renal disease (ESRD) who initiated HD sessions between July 2018 and December 2023 at Urmia Imam Khomeini hospital. The data collected for this study included patient demographics, underlying diseases, malignancy status, and duration of mali
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
Koichiro Yanai, MD, Tsuyoshi Tajika, MD, PhD, Yuhei Hatori, MD et al. · 2025 · JSES International
Background: An increase in carrying angle (CA) on the throwing side has been reported in professional baseball pitchers. However, no reports have investigated high school baseball pitchers, and the associated factors remain unknown. This study aimed to examine the difference in the CA between the throwing and nonthrowing sides in high school baseball pitchers and to investigate the association between the CA and medial instability of the elbow and general joint laxity (GJL). Methods: We surveyed 216 high school baseball pitchers who underwent medical checkups during the 2023-24 off-season. All
View details →Negative / Null Result ReportOpen accessMedicine (General)
Shichong Jia, Xuyang Wen, Min Zhou et al. · 2021 · Frontiers in Medicine
Purpose: To evaluate the efficacy of an external carotid artery (ECA) alternative route in intra-arterial chemotherapy (IAC) for treatment of retinoblastoma.Methods: In this retrospective, single-centre, case-control study, 98 retinoblastoma patients who received successful IAC were included. The drug delivery routes were the primary ophthalmic artery (OA) route and the ECA route when OA catheterization was not feasible.Results: A total of 337 successful IAC procedures were performed in our study, of which 32 (9.5%) procedures were performed through the ECA route. Eighteen eyes (18.4%) accepte
View details →Negative / Null Result ReportOpen accessMedicine
Arno C Hessels, Abraham Rutgers, Jan Stephan F Sanders et al. · 2018 · PLoS ONE
Azathioprine is a widely used immunosuppressive drug. Genetic polymorphisms and activity of the enzyme thiopurine methyltransferase (TPMT) have been associated with azathioprine efficacy and toxicity in several populations. We investigated whether these associations also exist for ANCA associated vasculitis (AAV) patients, who receive azathioprine maintenance therapy after remission induction with cyclophosphamide.207 AAV patients treated with cyclophosphamide induction and azathioprine maintenance therapy were included and followed for 60 months. TPMT genotype and tertiles of TPMT activity we
View details →Negative / Null Result ReportOpen accessMedicine (General)
Almansour A, Alagil J, Alamoudi NB et al. · 2022 · Journal of Multidisciplinary Healthcare
Abdulelah Almansour,1 Jumana Alagil,2 Naela B Alamoudi,3 Rahmah M Alamrie,3 Sundus Alarifi,4 Sarah AlUrifan,4 Abdullatif Althunyan,1 Abdullah Alghumlas,1 Abdullah Alreedy,1 Adam Aldhawyan,1 Shaher Alshehri,1 Arwa Alumran5 1Family and Community Medicine Department, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 3College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 4General Dentist, Ministry of Health, Dammam, Saudi Arabia; 5Health Information Man
View details →Negative / Null Result ReportOpen accessPublic aspects of medicine
Ulrike Stentzel, Jeanette Bahr, Daniel Fredrich et al. · 2018 · BMC Health Services Research
Abstract Background In rural regions with a low population density, distances to health care providers as well as insufficient public transport may be barriers for the accessibility of health care. In this analysis it was examined whether the accessibility of gynecologists and GPs, measured as travel time both by car and public transport has an influence on the utilization of health care in the rural region of Western Pomerania in Northern Germany. Methods Utilization data was obtained from the population based Study of Health in Pomerania (SHIP). Utilization was operationalized by the paramet
View details →Negative / Null Result ReportOpen accessMedicine
Shanshan Shi, Xiuchun Zhang, M Alejandra Mandel et al. · 2017 · PLoS ONE
Cassava (Manihot esculenta) is an important tropical subsistence crop that is severely affected by cassava brown streak disease (CBSD) in East Africa. The disease is caused by Cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV). Both have a (+)-sense single-stranded RNA genome with a 5' covalently-linked viral protein, which functionally resembles the cap structure of mRNA, binds to eukaryotic translation initiation factor 4E (eIF4E) or its analogues, and then enable the translation of viral genomic RNA in host cells. To characterize cassava eIF4Es and their potent
View details →Negative / Null Result ReportOpen accessDentistry
Ramtin Azar, Hassan Semyari, Mohamad Javad Kharazifard · 2020 · Frontiers in Dentistry
Objectives: This study aimed to compare the oral health related quality of life (OHRQoL) of patients using conventional dentures versus implant-supported overdentures. Materials and Methods: This study evaluated the OHRQoL of 90 patients between 35 to 75 years who were selected from several public and private dental clinics in Tehran in 2018. Of all, 45 had conventional dentures of both jaws, and 45 had a mandibular overdenture supported by two implants at the site of mandibular canine teeth and a conventional maxillary denture. The OHRQoL of patients was determined using the Oral Health Impac
View details →Negative / Null Result ReportOpen accessMedicine
Linh Tran, Jeah Jung, Roger Feldman et al. · 2022 · PLoS ONE
Purpose Chronic hepatitis C virus (HCV) infection is an important public health concern. Limited information exists on disparities in the quality of HCV care. We examine disparities in genotype or quantitative HCV ribonucleic acid testing before and after starting HCV treatment, and screening for hepatocellular carcinoma (HCC) in HCV patients with cirrhosis. Methods This national study included Medicare beneficiaries with HCV between 2014 and 2017. We used bivariate probit to estimate the probability of receiving recommended tests before and after HCV treatment by patient race/ethnicity, urban
View details →Negative / Null Result ReportOpen accessMedicine
F. E. Kocak, M. Yöntem, Ö. Yücel et al. · 2013 · Biochemia Medica
Introduction: Today, the pneumatic tube transport system (PTS) is used frequently because of its advantages related to timing and speed. However, the impact of various types of PTS on blood components is unknown. The aim of this study was…
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Priyadharshini Mohan, Karthika Priyadharshini Udayakumar, Hiramath PB · 2020 · National Journal of Physiology, Pharmacy and Pharmacology
Back ground: In addition to the imbalance in the cardiac autonomic function, deficiency of micronutrients such as zinc (Zn), magnesium, and copper (Cu) was also found to be one of the cause of hypertensive disorders of pregnancy. Although there are number of studies done to know the autonomic balance and serum trace elements among preeclamptic women, none of the studies were done among the gestational hypertensives, hence, we have chosen this study on association between the level of micronutrients and frequency domain parameters of heart rate variability (HRV) among newly diagnosed gestationa
View details →Negative / Null Result ReportOpen accessEnvironmental sciences
Bouziani Amina, Benkirane Hasnae, Idrissi Mohamed et al. · 2021 · E3S Web of Conferences
In addition to age, gender, body weight, hormonal status as well as certain physiological and pathological states, other factors exert considerable effects on calcium (Ca) retention and therefore on its urinary excretion. Among these other factors, many dietary nutrients have all been discussed as factors affecting urinary Ca through different studies. Thus, our study aims to evaluate the impact of various nutritional factors on urinary Ca excretion among a sample of Moroccan children and adolescents aged from 6 to 18 years old. A total of 133 Moroccan children and adolescents aged between 6 a
View details →Negative / Null Result ReportOpen accessDentistry
Ziyao Han, Cui Wang, Yiping Wei et al. · 2022 · BMC Oral Health
Abstract Background Assessment of the keratinized mucosa width (KMW) at edentulous sites is important for the subsequent implant treatment design. This pilot study aimed to evaluate the characteristics of the KMW at edentulous molar sites and explore the associated factors. Methods A total of 150 patients with 222 edentulous molar sites were included. The buccal KMW of the edentulous molar sites was measured during implant treatment planning. Potentially associated factors, including age, sex, smoking status, location, reasons for tooth loss/extraction, gingival phenotype (GP) and keratinized
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