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Browse the failure-mode index

19,915 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Incline and decline treadmill trotting produce electromyographic changes in specific canine shoulder muscle activity: implications for therapeutic exercise.

Stanford K, Cain RM, Millis D et al. · 2026 · American journal of veterinary research

Objective To identify the effects of incline and decline treadmill trotting on forelimb muscle activity in dogs using electromyography (EMG). Methods Data were collected for a prospective within-subject, repeated-measures study in January…

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Negative / Null Result ReportMedicine

Corneal epithelial morphological changes in orthokeratology lens wearers.

Qasim MSA, Kang P, Evans B et al. · 2026 · Contact lens & anterior eye : the journal of the British Contact Lens Association

Purpose To investigate the utility of in vivo confocal microscopy (IVCM) combined with standardized image grading for identifying early morphological changes in the central corneal and superior limbal basal epithelial cells during…

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Negative / Null Result ReportOpen accessMedicine

Role of Ethnicity and Age in Corneal Curvature and Thickness Changes Following Corneal Cross-Linking for Keratoconus.

Alenezi BM, Khoyratty F, Biswas S et al. · 2026 · Translational vision science & technology

Purpose To investigate the effect of corneal cross-linking (CXL) on corneal curvature and thickness in two different keratoconic populations, one based in the Middle East (Saudi Arabia) and one in Europe (UK), and to explore whether age…

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Negative / Null Result ReportMedicine

Evaluation of the Effect of <i>Astragalus membranaceus</i> Saponins Administration on Knee Function and Cartilage Biomarkers in Healthy Subjects with Knee Discomfort.

Zhuang SR, Leong PY, Chiang HP et al. · 2026 · Nutrients

Objective This study aimed to evaluate the effects of 12 weeks of Astragalus membranaceus saponins (AMS) supplementation on functional performance, knee joint mobility, self-reported outcomes, and biomarkers of inflammation and cartilage…

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Negative / Null Result ReportMedicine

Erythropoietin and Hematological Responses in Recreational Scuba Divers: Insight into the Hyperoxic-Hypoxic Paradox.

Perović A, Juričić G, Bratičević MN et al. · 2026 · Medicine and science in sports and exercise

Purpose During scuba diving, breathing under elevated pressure leads to hyperoxia, which may induce oxidative stress and erythrocyte damage. Hyperoxia may also influence erythropoietin (EPO) production, a phenomenon referred to as the…

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Negative / Null Result ReportMedicine

Compatibility and physicochemical stability of ceftriaxone for injection admixed with pantoprazole sodium and ondansetron hydrochloride in different infusion solutions.

Dobariya A, Patel R, Patel M · 2026 · European journal of hospital pharmacy : science and practice

Objective The study aimed to analyse the physicochemical stability and compatibility of ceftriaxone sodium (CEF) (2mg/mL) with pantoprazole sodium (PAN) (0.08mg/mL) and ondansetron hydrochloride (OND) (0.008mg/mL) in different infusion…

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Negative / Null Result ReportMedicine

Three-Dimensional Speckle-Tracking Echocardiography-Derived Aortic Valve Annular Plane Systolic Excursion and Left Ventricular Volumes Are Not Associated in Healthy Adults (Insights from MAGYAR-Healthy Study).

Nemes A, Ambrus N, Szili-Török T et al. · 2026 · Journal of clinical medicine

Introduction : The left ventricular (LV) function can be characterized by the spatial displacement of the aortic valve annulus (AVA), represented by the AVA plane systolic excursion (AAPSE). AAPSE, measured using 3DSTE, has been shown to…

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Negative / Null Result ReportMedicine

EEG connectivity changes in early response to antidepressant treatment.

Kathpalia A, Vlachos I, Hlinka J et al. · 2026 · Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

Objective Finding indicators of early response to antidepressant treatment in EEG signals recorded from patients suffering from major depressive disorder. Methods Functional brain connectivity networks based on weighted imaginary coherence…

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Negative / Null Result ReportOpen accessMedicine

Statistical shape modeling of MRI-based morphological response of lumbar intervertebral discs to a unilateral side lying spinal rotation mobilization.

Putos J, Atkinson HF, Walton DM · 2026 · Osteoarthritis and cartilage open

Objectives The acute response of lumbar intervertebral discs (IVD) to spinal rotation mobilization (SRM) is poorly understood. We evaluated sustained morphological changes in lumbar IVDs following a rotation mobilization commonly used to…

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Negative / Null Result ReportMedicine

Acute and Long-Term Effects of Spinning-Based High-Intensity Interval Training on Inducible Nitric Oxide Synthase: A Randomized Controlled Trial.

Uysal A, Soslu R, Soslu R · 2026 · Journal of strength and conditioning research

Abstract Uysal, A and Soslu, R. Acute and long-term effects of spinning-based high-intensity interval training on inducible nitric oxide synthase: a randomized controlled trial. J Strength Cond Res XX(X): 000-000, 2026-This study…

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