20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Kieri O, Jütte BB, Vesterbacka J et al. · 2026 · HIV medicine
Background The potent immunogenicity of mRNA vaccination raised concerns about its impact on HIV-1 viral load (VL) and reservoir size in people with HIV, which could drive vaccine hesitancy. As part of a prospective clinical trial, we…
View details →Glass-Biran AH, Eyre A, Stein G et al. · 2026 · BMJ open quality
Objective To evaluate whether adding a fourth physician to the emergency department night shift would improve metrics. Methods This retrospective cohort study used data from the Meir Medical Centre emergency department, 1 January 2021 to…
View details →Eliasson TM, Lundh Å, Höjer A et al. · 2026 · International Dairy Journal.
The objectives were to evaluate effects of feeding different types of silages on the microbiota of the raw milk and the resulting cheeses. Different silages were produced without additives, acid treated and inoculated with a LAB starter…
View details →Caso JM, Fernández-Ruiz M, González E et al. · 2026 · Transplantation
Background Observational studies have shown that kidney transplant (KT) recipients who are cytomegalovirus (CMV)-seropositive (R+) but lack effective CMV-specific cell-mediated immunity (CMV-CMI) are at increased risk of CMV infection.…
View details →Strand DD, Ruf S, Sandoval-Ibáñez O et al. · 2026 · Plant physiology
The physiological role of the plastidial photosynthetic complex I (formerly NAD(P)H dehydrogenase-like complex, NDH) within the electron transport chain of plants remains intriguing. While the NDH complex shares homology with complex I, a…
View details →Majeed A, Majeed S, Pandey A et al. · 2026 · Phytotherapy research : PTR
Withania somnifera , commonly known as Ashwagandha, is a widely recognized medicinal plant in India, belonging to the family Solanaceae, used in Ayurveda due to its diverse therapeutic properties. The roots of Ashwagandha are considered…
View details →Koh A · 2025 · Preprint
Duplication and segregation of genetic material are vital for cell proliferation. Deletion of DNA replication regulators, such as YabA and ParA, leads to over initiation of DNA replication. However, the viability of the ΔyabA ΔparA double…
View details →Ali R, Yazdi A, Collins K et al. · 2026 · International journal of critical illness and injury science
Background Thiamine is a vitamin that plays a role in lactate clearance. Patients with sepsis may present with elevated lactate, and also in cirrhosis, as lactate is hepatically metabolized. Prior studies showed mixed results regarding the…
View details →Quiroga-Murcia DE, Dos Santos ÉA, Schutter K et al. · 2025 · Journal of insect physiology
Nuclease (RNase) activity is a major limiting factor that reduces the effectiveness of RNAi-induced gene silencing across many insect species. In Euschistus heros, dsRNA degradation occurs predominantly upon contact with saliva, while…
View details →Chew BMH, Lim SSA, Gan TRX et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Objective There is increasing use of intraoperative parathyroid hormone (ioPTH) in minimally invasive parathyroidectomy (MIP). While ioPTH has improved cure rate, there is little evidence to suggest effectiveness in primary…
View details →Li Q, Li J, Zhang Y et al. · 2026 · Journal of ethnopharmacology
Ethnopharmacological relevance Wujin, a mineral-derived Chinese medicine first recorded in the "Compendium of Materia Medica" (Bencao Gangmu), has been widely employed in the management of inflammatory conditions for millennia. Comprising…
View details →Hoppermann R, Kirsch J, Pilsl T et al. · 2026 · Journal of clinical medicine
Background/Objectives: Whispering has frequently been recommended to patients in order to avoid vocal overuse, particularly in those with organic dysphonia. However, there is controversy as to whether whispering may negatively affect vocal…
View details →Hosseinzadeh F, Nourazarian A · 2025 · Updates in surgery
Laparoscopic cholecystectomy (LC) has become the standard management for gallstones. However, it is associated with postoperative elevations in liver enzymes. This scoping review of 52 studies involving over 28,000 patients was undertaken…
View details →Shih CM, Yen YC, Wang CH et al. · 2026 · Bioengineering (Basel, Switzerland)
Jones fractures are Zone 2 fractures of the fifth metatarsal. Biomechanical comparisons of fixation strategies for Jones fractures remain limited by the lack of standardized, head-to-head evaluations across major fixation methods. The…
View details →Stevenson E, Ponder M, Daniels L et al. · 2026 · The Journal of antimicrobial chemotherapy
Objectives While tigecycline has been associated with hypofibrinogenaemia, limited data with eravacycline suggest this may also occur with this agent. However, the incidence and clinical significance of this finding are not well defined.…
View details →Sarikaya G, Paksoy AE, Karaşahin Ö et al. · 2026 · Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca
Purpose of the study The purpose of this prospective study was to compare the two surgical techniques; (Transosseous Fixation with the Suspensory Fixation System technique and Pull Out Suture Repair) for clinical and radiologic scores and…
View details →Wu HD, Dederichs B · 2025 · Preprint
Abstract This study unveils and compares the outcomes of distinct mediated public diplomacy strategies employed by China and Taiwan by content-analyzing their resulting news coverage in German and U.S. press. The key diplomats dispatched…
View details →Peake SL, Macdonald SPJ, Howe BD et al. · 2026 · The New England journal of medicine
Background The optimal approach to early resuscitation in septic shock is unknown. Equipoise exists between the use of larger volumes of intravenous fluids to restore perfusion and the use of early vasopressor therapy along with smaller…
View details →Wang YX, Holz FG, Coenen M et al. · 2026 · Preprint
Abstract Background Epidermal growth factor (EGF) has been suggested to play a role in myopic axial elongation, and EGF receptor blockade may be of potential therapeutic benefit. Here we examined the ocular and systemic toxicity of…
View details →Alaka MO, Ogunjobi JK, Omoruyi OE et al. · 2026 · Scientific reports
This study addresses the environmental challenges posed by the waste generated during the extraction of cashew nut shell (CNS) liquid by proposing a sustainable repurposing method. Extracted CNS (waste) was pyrolyzed at varying…
View details →Coticchio LA, Cassill DL · 2026 · Journal of medical entomology
Recluse spiders are arachnids of potential medical significant due to their necrotic venom. However, in areas populated by the brown recluse, Loxosceles reclusa, bites and necrosis are rare. In Florida, USA, public media reports and…
View details →Rupietta AE, Meyer T, Margraf J et al. · 2026 · Journal of behavior therapy and experimental psychiatry
Background Cognitive theories on trauma memory postulate that trauma-related intrusions are associated with more data-driven and less contextual processing. However, contextualisation can be enhanced via verbalization, suggesting that…
View details →Grue C, Getsinger KD, Heilman MA et al. · 2026 · Environmental toxicology and chemistry
Florpyrauxifen-benzyl (aquatic tradename ProcellaCOR) is an aquatic herbicide commonly used to control Eurasian watermilfoil (Myriophyllum spicatum) and other invasive aquatic plants. Previous studies have demonstrated effective Eurasian…
View details →Thuluva S, Gunneri S, Ningaiah S et al. · 2026 · Vaccines
Background: Pneumococcal conjugate vaccines (PCVs) have substantially reduced pneumococcal disease in children; however, serotype distribution varies geographically, and residual disease due to non-PCV13 serotypes persists. Biological E's…
View details →Oltrogger FT, Howe G, McNevin D et al. · 2026 · Science & justice : journal of the Forensic Science Society
Over the last few years, additive manufacturing, by means of fused deposition modelling 3D printing, has become increasingly popular and accessible due to the relative low costs, flexibility, and continually lowering barriers for entry.…
View details →Achatz V, Sebastian S, Mitterer JA et al. · 2026 · The Journal of arthroplasty
Background Gram-negative (GN) periprosthetic joint infections (PJIs) are still less frequent than gram-positive (GP) PJIs. There is only little data available on a direct comparison of GP- and GN-associated PJIs. Therefore, we investigated…
View details →Li L, Gao S, Zhu H et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Introduction Frozen embryo transfer offers improved cumulative pregnancy rates and reduces complications compared to fresh cycles. Successful outcomes depend on both embryonic potential and endometrial receptivity, necessitating…
View details →Holtkamp M, Jost G, Salhöfer L et al. · 2026 · RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
Purpose The effect of iodine preparation concentration on vascular attenuation during computed tomography angiography (CTA) is a topic of controversy. Iodine-based contrast media (CM) formulations are used in different iodine preparation…
View details →Bauerle WB, Allsbrook A, Green A et al. · 2026 · Surgical infections
Introduction Surgical site infections (SSIs) are a substantial contributor to morbidity and mortality rates. 405 nm visible light disinfection (VLD) has been shown to reduce bacterial burden in operating rooms (ORs); however, its effect on…
View details →van Norden SJ, Kho KH, Meppelink AM et al. · 2026 · Epilepsy & behavior : E&B
Objective Vagus nerve stimulation (VNS) is a therapeutic option for pharmacoresistant epilepsy patients who are not eligible for surgery. While its primary aim is seizure reduction, the effects of VNS on sleep remain unclear, with previous…
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