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WASTE Journal

Browse the failure-mode index

19,906 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Arrhythmic Risk and Clinical Features in Catecholaminergic Polymorphic Ventricular Tachycardia: Results From a Multicenter Study in Korea.

Cho MJ, Song MK, Jun SY et al. · 2025 · The American journal of cardiology

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare but life-threatening inherited arrhythmia in children, often associated with sudden cardiac death (SCD). Risk stratification remains challenging. This study aimed to…

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Negative / Null Result ReportOpen accessMedicine

Diverticular perforation with exclusive local invasion in cytomegalovirus infection during ganciclovir treatment: an autopsy case report.

Ishiguro Y, Kuriyama A, Ishiguro S · 2025 · Annals of medicine and surgery (2012)

Introduction and importance Cytomegalovirus (CMV) can cause severe colitis in immunocompromised patients. While its morphological manifestations vary, diverticular perforation is rare, with most lesions remaining intact. We report a rare…

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Negative / Null Result ReportMedicine

Oxidative Stress Parameters are Differentially Regulated in Visceral and Subcutaneous Adipose Tissue by Western Diet and Intermittent Fasting.

Correia de Lima Junior N, Fernandes-Batista T, Ferreira-Serra L et al. · 2025 · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

The consumption of Western diet, characterized by high sugar and saturated fat content, often leads to weight gain and promotes oxidative stress. Intermittent fasting has emerged as a potential strategy to combat obesity, but its effects…

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Negative / Null Result ReportMedicine

Orally administered Cannabigerol (CBG) in rats: Cannabimimetic actions, anxiety-like behavior, and inflammation-induced pain.

Weerts EM, Jenkins BW, Kuang RY et al. · 2024 · Pharmacology, biochemistry, and behavior

Cannabigerol (CBG) is a phytocannabinoid found in cannabis that is promoted for medical use and other health benefits, but current empirical data on the behavioral effects of CBG are lacking. The purpose of this study was to evaluate the…

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Negative / Null Result ReportOpen accessMedicine

Progression of cortical hypertrophy, subsidence and thigh pain after short curved fitmore femoral hip stem over 10 years.

Maier KS, Schiener T, Frigg A · 2025 · Journal of orthopaedic surgery and research

Background Short femoral stems were introduced for total hip arthroplasty (THA) to preserve bone stock, increase proximal load transfer, and enable minimal invasive approaches. However, after implanting the short curved Fitmore hip stem,…

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Negative / Null Result ReportOpen accessMedicine

Does Consuming Fresh Ultraviolet Light-Exposed Mushrooms Offset the Seasonal Decline in Serum Total 25OHD in Adults Classified as Overweight and Class I Obese? Results from a Randomized Controlled Trial.

Comboni LM, Glover ES, Napolitano SC et al. · 2026 · Foods (Basel, Switzerland)

We assessed whether consuming UV light-exposed mushrooms (UVMs) would offset the seasonal decline in circulating total 25-hydroxyvitamin D (25OHD), an index of vitamin D status. During late fall and winter, 41 adults (19 M/22 F, age 43 ±…

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Negative / Null Result ReportOpen accessMedicine

Effect of low-dose atropine on young premyopic and low-myopic children: atropine treatment of myopia (ATOM3) - a randomised control trial.

Chia A, Burkill S, Ling Y et al. · 2026 · The British journal of ophthalmology

Aim To evaluate the effectiveness of atropine 0.01% in young premyopic and low-myopic children. Methods Children (5-9 years old) with premyopia (spherical equivalent refraction, SER+1.00 to -0.49D, n 156) or low myopia (SER -0.50 to…

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Negative / Null Result ReportOpen accessMedicine

Convalescent plasma therapy for COVID-19 prophylaxis in adults early post-hematopoietic stem cell transplantation: one-year outcomes from a randomized controlled trial.

Cao Y, Li Q, Guo W et al. · 2025 · Frontiers in immunology

To evaluate the efficacy of COVID-19 convalescent plasma (CCP) in preventing SARS-CoV-2 infection in hematopoietic stem cell transplantation (HSCT) recipients during the early post-transplant period, a single-center, randomized controlled…

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Negative / Null Result ReportOpen accessMedicine

Role of β-Arrestin 2 in the antinociceptive and side effect profile of morphine and the novel mu opioid receptor agonists, kurkinorin and kurkinol.

van de Wetering R, Alder AF, Biggerstaff A et al. · 2025 · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

The development of safer mu opioid receptor (MOR) agonists with reduced side effects is a key focus of pain research. Some studies have suggested that MOR agonists with reduced β-arrestin 2 (βArr2) signaling (i.e. G-protein biased…

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Negative / Null Result ReportOpen accessMedicine

Rate of growth of Merkel cell carcinoma: a unique photographic evidence.

Bearzi E, Sola S, Defferrari C et al. · 2026 · Dermatology reports

Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin tumor, mainly linked to Merkel cell polyomavirus (MCPyV) and less often to ultraviolet exposure. Additional risk factors include advanced age and immunosuppression.…

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Negative / Null Result ReportOpen accessMedicine

Fluorescent Light Energy in Feline Surgical and Traumatic Wounds: A Prospective Single-Arm Pilot Study of Healing Progression and Bacterial Findings.

Nocera FP, Fantini O, Abate G et al. · 2026 · Veterinary medicine and science

Background Traumatic and surgical wounds are common in cats, but their management is often challenging due to anatomical factors, delayed presentation, behavioural issues and frequent bacterial colonization. Objectives This prospective,…

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Negative / Null Result ReportMedicine

Prevalence, risk factors and the impact of tenofovir treatment in SARS-CoV-2 infection and COVID-19 disease among people living with HIV: A cross-sectional population-based study.

de Lazzari E, Nomah DK, Blanco JL et al. · 2024 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Objectives The prevalence and risk factors of SARS-CoV-2 infection among unvaccinated people living with HIV (PWH) are not well understood, and the protective role of tenofovir remains controversial. This study aimed to assess the…

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Negative / Null Result ReportOpen accessMedicine

Aicardi-Goutières syndrome type 6: report of ADAR variant and clinical outcome after ruxolitinib treatment in the neonatal period.

Gabaldon-Albero A, Martin-Grau C, Marti-Masanet M et al. · 2024 · Pediatric rheumatology online journal

Background Aicardi-Goutières Syndrome is a monogenic type 1 interferonopathy with infantile onset, characterized by a variable degree of neurological damage. Approximately 7% of Aicardi-Goutières Syndrome cases are caused by pathogenic…

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