Negative / Null Result ReportOpen accessMedicine
Böckels L, Lisnic V, Alexa D et al. · 2026 · Journal of clinical medicine
Background/Objectives: Relapsing-remitting multiple sclerosis (RRMS) is frequently associated with anxiety and depressive symptoms, which significantly impact quality of life and clinical outcomes. The Hospital Anxiety and Depression Scale…
View details →Negative / Null Result ReportMedicine
Shimada H, Lee S, Doi T et al. · 2026 · Gerontology
Introduction Walking speed is widely recognized as an informative indicator of physical capability in later life and is frequently used to evaluate mobility and functional health in older adults. Although the measurement of community…
View details →Negative / Null Result Report
Demirbaş SC, Kaba İ, Yilmaz M et al. · 2026 · Preprint
Abstract Objective Childhood obesity is a significant public health issue. Meteorin-like protein (Metrnl) is a newly identified adipomyokine that plays a role in energy metabolism and inflammatory processes. The aim of this study was to…
View details →Negative / Null Result ReportOpen accessMedicine
Rosi Júnior J, Telles JPM, Santana LS et al. · 2026 · Arquivos de neuro-psiquiatria
Background Alpha 1-antitrypsin (A1AT) helps maintain vascular-wall integrity, but its role in the formation and rupture of intracranial aneurysms is unclear. Objective To compare A1AT levels between patients with ruptured and unruptured…
View details →Negative / Null Result ReportMedicine
Kavrul Kayaalp G, Balcı MC, Kürkçü Güneş D et al. · 2026 · Cardiology in the young
Background Early identification of familial hypercholesterolaemia is critical to prevent long-term cardiovascular complications. This study assessed diagnostic features and age at diagnosis in children with familial hypercholesterolaemia…
View details →Negative / Null Result ReportMedicine
Shinkawa K, Yoshida S, Nakao YM et al. · 2026 · Clinical and experimental nephrology
Introduction The clinical characteristics of patients with nephrotic syndrome undergoing in-hospital rehabilitation are not well-understood, and the effects of exercise on acute kidney injury (AKI) or venous thromboembolism (VTE) in this…
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Conteville LV, Fernandes JPA, Frajacomo FT et al. · 2026 · Preprint
Abstract OBJECTIVES To examine the association between longitudinal trajectories of anthropometric nutritional status, physical activity, and overall survival among women with endometrial cancer. METHODS In a prospective cohort study, we…
View details →Negative / Null Result ReportOpen accessMedicine
Kim T, Oh SB, Choi HJ et al. · 2025 · Genes
Objective Suicide attempts have become one of the most serious problems worldwide in recent years. Suicide attempts are known to be genetically highly associated with serotonin and BDNF in international studies. Methods In this study, we…
View details →Negative / Null Result ReportMedicine
Devi Krishna RB, Mathews SG, Agarwal P et al. · 2026 · Biochemical genetics
To assess the potential association between LRP1 (rs715948) and PAI1 (rs2227631, rs1799889) gene variation and ovarian cancer (OC) susceptibility. This study evaluated the genotypic and allelic distributions of LRP1 gene and PAI1 gene…
View details →Negative / Null Result Report
Ma L, Ma Y, Huang Z et al. · 2026 · Preprint
Abstract Background: Stroke remains a leading cause of death and disability among older adults. Depressive symptoms and low social participation may increase stroke risk via behavioural and biological pathways. This study examined the…
View details →Negative / Null Result ReportOpen accessMedicine
Majmudar IP, Aggarwal S, Hamzeh N et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)
Purpose To determine if there is an association between surgeon-patient sex concordance and post-surgical complications for cataract surgeries. Patients and methods In this 16-year retrospective cohort study, data was collected from the…
View details →Negative / Null Result ReportMedicine
Foo JF, Haddow K, Jones S et al. · 2026 · The Journal of laryngology and otology
Objectives To investigate whether socioeconomic deprivation is associated with residual or recurrent cholesteatoma following primary mastoidectomy. Methods A retrospective cohort study included all patients undergoing primary mastoidectomy…
View details →Negative / Null Result ReportMedicine
Peng P, Guo Y, Zhu Y · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Background Given that long-term anticoagulant therapy is required in many clinical scenarios, continuous safety monitoring of direct factor Xa inhibitors is of great importance. To date, the renal safety of these agents remains a subject…
View details →Negative / Null Result ReportMedicine
Zhai L, Fang C, Wang L et al. · 2026 · Scientific reports
There is little evidence about the susceptible exposure window of maternal depression during pregnancy and preterm birth in China. We aimed to assess the trimester-specific association of depression during pregnancy with preterm birth, and…
View details →Negative / Null Result ReportOpen accessMedicine
Metwally YF, Zahran RF, El Sadda RR et al. · 2026 · Discover oncology
Background Lung cancer remains the leading cause of cancer-related deaths worldwide. Despite advances in diagnostics and treatment, most patients are diagnosed at advanced stages. Genetic variants such as single nucleotide polymorphisms…
View details →Negative / Null Result ReportMedicine
Aryal SB, Raj Joshi D · 2026 · Journal of Nepal Health Research Council
Background Homocysteine (Hcy) contributes to oxidative stress and renal injury by generating reactive oxygen species and reducing heme oxygenase-1 levels. Elevated Hcy (Hhcy) may worsen outcomes after acute renal failure(ARF), promoting…
View details →Negative / Null Result ReportMedicine
Bellos I, Marinaki S, Benetou V · 2026 · Journal of clinical medicine
Background/Objectives : Composite endpoints are commonly used in chronic kidney disease (CKD) trials to enhance statistical efficiency but may not reflect clinically meaningful outcomes. We assessed agreement between composite endpoints…
View details →Negative / Null Result ReportMedicine
Pires E Silva C, Malaspina OA, Basting RT · 2026 · General dentistry
Light transmission during photopolymerization is reduced by the intrinsic optical properties of ceramics, which vary with material and thickness. The higher translucency of lithium disilicate contrasts with the chemical inertness and…
View details →Negative / Null Result ReportMedicine
Chaudhry A, Moin M, Malik TG et al. · 2026 · JPMA. The Journal of the Pakistan Medical Association
To determine the shape and size of foveal avascular zone in terms of perimeter, circularity, roundness and axial ratio using optical coherence tomography angiography. The retrospective study was conducted at the Yaqeen Vison Clinic,…
View details →Negative / Null Result ReportMedicine
He L, Wang K · 2026 · Medicine
Total bilirubin possesses antioxidant and immunomodulatory properties, and its role in childhood asthma is a topic of ongoing debate. We employed both a cross-sectional study and Mendelian randomization (MR) analysis to explore the link…
View details →Negative / Null Result ReportMedicine
Wei W, Shaibi GQ, Temkit H et al. · 2026 · Journal of pediatric hematology/oncology
Introduction Alkylators are gonadotoxic in a cumulative manner, with overall exposure quantified as the cyclophosphamide equivalent dose (CED). Inhibin B is used as a surrogate marker of fertility in adult male childhood cancer survivors…
View details →Negative / Null Result ReportOpen accessMedicine
Barghash M, Obayi E, Itaman U et al. · 2025 · Cureus
Background Hiatal hernia is commonly associated with gastro-oesophageal reflux disease (GORD). However, the relationship between hernia size and reflux severity remains unclear. This study aimed to assess the impact of the hiatal hernia…
View details →Negative / Null Result ReportOpen accessMedicine
Md Kasim NA, Shirinal Izuan US, Karuppannan M · 2026 · BMC health services research
BACKGROUND: Healthcare providers commonly recommend medication reminders as a strategy to enhance adherence to prescribed medications. Patient demographic characteristics may influence medication adherence and incorporating patient-centred…
View details →Negative / Null Result ReportOpen accessMedicine
Prates AJ, Curioni OA, Ramos DM et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives: Laryngeal cancer has a high incidence and mortality rate, especially in advanced stages. Stoma recurrence after total laryngectomy is rare but lethal, and its risk factors remain controversial. We aimed to assess…
View details →Negative / Null Result ReportMedicine
Voigt MB, Böhner A, Bahaaeldin M et al. · 2026 · CVIR endovascular
To evaluate the occurrence of periaortic inflammation, including abscess formation, as a complication following endoleak repair after endovascular aortic repair. This retrospective single-center study analyzed 88 EVAR revisions for…
View details →Negative / Null Result ReportMedicine
Zhao N, Zhan Y, Choi J et al. · 2026 · The Journal of nutrition
Background The consumption of live microbes beyond probiotics is associated with health benefits. Despite growing interest in live microbe intake, comprehensive data on its dietary sources and research on their potential health effects in…
View details →Negative / Null Result ReportOpen accessMedicine
Mostafavi M, Rezazadeh F, Fattahi MJ et al. · 2026 · Journal of dentistry (Shiraz, Iran)
Background Multiple studies have revealed an association between vitamin D levels, genetic polymorphisms of the VDR (vitamin D receptor) gene, and the underlying causes of various bone and cartilage disorders. Purpose This study aimed to…
View details →Negative / Null Result ReportMedicine
Ozaki K, Nishioka Y, Kamitani F et al. · 2026 · Diabetes research and clinical practice
It has been controversial whether COVID-19 increases the risk of new-onset type 1 diabetes mellitus. Using large-scale claims data, we found no statistically significant association between COVID-19 and incident type 1 diabetes mellitus in…
View details →Negative / Null Result ReportMedicine
Lukies M, Darby O, Wani S et al. · 2026 · Journal of medical imaging and radiation oncology
Uterine artery embolisation (UAE) is an evidence-based treatment for symptomatic fibroids and adenomyosis. Ultrasound is commonly utilised for assessment post UAE given its wide availability and low cost; however, contemporary studies…
View details →Negative / Null Result ReportOpen accessMedicine
Karatutlu AS, Karatutlu MA, Aydin S · 2026 · Renal failure
Chronic kidney disease (CKD) is characterized by progressive renal fibrosis and irreversible loss of kidney function. Decorin, an extracellular matrix proteoglycan with antifibrotic properties, may reflect underlying fibrotic activity and…
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