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20,261 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Altermagnetic and Dipolar Splitting of Magnons in FeF_{2}.

Sears J, Garlea VO, Lederman D et al. · 2026 · Physical review letters

FeF_{2} is a prototypical rutile antiferromagnet recently proposed as an altermagnet, with a magnetic symmetry that permits spin-split electronic bands and chiral magnons. Using very-high-resolution inelastic neutron scattering on a single…

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Negative / Null Result ReportMedicine

The mediating role of job performance and satisfaction in the effect of digital leadership on heavy workload among healthcare workers.

Sağbaş M, Oktaysoy O, Topcuoglu E · 2026 · Journal of health organization and management

Purpose This study aims to investigate the mediating roles of job performance and job satisfaction in the effect of digital leadership on heavy workloads among healthcare workers. By focusing on the phenomenon of leadership in digital…

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Negative / Null Result ReportMedicine

The effect of the liquid motion bubbler timer soothing sensory toy on children's fear and anxiety levels during blood sampling: a randomized clinical trial.

Sariali̇oğlu A, Oluç T · 2026 · BMC psychology

Background Blood sampling is one of the invasive procedures in a hospital setting that can cause fear, anxiety, and stress in children. Aim The study aimed to determine the effect of the Liquid Motion Bubbler Timer Soothing Sensory Toy on…

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Negative / Null Result ReportOpen accessMedicine

An improved translational approach to studying persistence-strengthening effects of differential reinforcement of alternative behavior.

Layton KL, Edwards TL, Foster TM · 2026 · Journal of the experimental analysis of behavior

Translational research investigating traditional differential reinforcement of alternative behavior (DRA) suggests that such procedures increase the persistence of target behavior relative to when the alternative behavior is first…

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Negative / Null Result ReportOpen accessInfectious and parasitic diseases

ASSOCIATION BETWEEN FAS/FASL EXPRESSION AND RHEUMATOLOGICAL MANIFESTATIONS IN PATIENTS INFECTED WITH HTLV-1

Aline Cecy Rocha de Lima, Wandrey Roberto dos Santos Brito, Luciana Cristina Coelho Pantoja Santos et al. · 2026 · Brazilian Journal of Infectious Diseases

Introduction: Fas and FasL are known modulators of cellular apoptosis in immunoregulation of the innate immune response, as well as in the elimination of defective cells, and may be associated with antiviral activity of HTLV-1 – infected cells. Understanding the immunological mechanisms involved in the progression of HTLV-1 – associated diseases may contribute to predicting the clinical prognosis of infected individuals. Objective: To evaluate mRNA expression of the apoptotic modulators FAS and FASL in patients infected with HTLV-1. Methods: A total of 54 HTLV-1 – infected individuals were eva

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Negative / Null Result ReportOpen accessTechnology

Influence of the Process Parameters on the Mechanical Properties of the FDM 3D Printed Samples

Sara Havrlišan, Martina Tokić, Štefanija Klarić et al. · 2026 · Tehnički Glasnik

This research analyses the impact of infill density and layer thickness on the tensile strength of test samples fabricated using FDM 3D printing, with a particular focus on comparing samples produced with and without an adhesion layer. A two-factor factorial experimental design was employed, consisting of two levels and three replications. The infill density (20% and 50%) and layer thickness (0.1 mm and 0.2 mm) were defined as input variables, while tensile strength served as the output variable. Statistical methods, such as ANOVA, were used to analyse the experimental data and evaluate the si

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Negative / Null Result ReportOpen accessDentistry

Minimal alterations on the enamel surface by micro-abrasion: in vitro roughness and wear assessments

Marcela Charantola Rodrigues, Rafael Francisco Lia Mondelli, Gabriela Ulian Oliveira et al. · 2013 · Journal of Applied Oral Science

Objective: To evaluate the in vitro changes on the enamel surface after a micro-abrasion treatment promoted by different products. Material and Methods: Fifty (50) fragments of bovine enamel (15 mm × 5 mm) were randomly assigned to five groups (n=10) according to the product utilized: G1 (control)= silicone polisher (TDV), G2= 37% phosphoric acid (3M/ESPE) + pumice stone (SS White), G3= Micropol (DMC Equipment), G4= Opalustre (Ultradent) and G5= Whiteness RM (FGM Dental Products). Roughness and wear were the responsible variables used to analyze these surfaces in four stages: baseline, 60 s an

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Negative / Null Result ReportOpen accessMedicine

Clinical outcomes in low risk coronary artery disease patients treated with different limus-based drug-eluting stents--a nationwide retrospective cohort study using insurance claims database.

Chao-Lun Lai, Ching-Fen Wu, Raymond Nien-Chen Kuo et al. · 2015 · PLoS ONE

The clinical outcomes of different limus-based drug-eluting stents (DES) in a real-world setting have not been well defined. The aim of this study was to investigate the clinical outcomes of three different limus-based DES, namely sirolimus-eluting stent (SES), Endeavor zotarolimus-eluting stent (E-ZES) and everolimus-eluting stent (EES), using a national insurance claims database. We identified all patients who received implantation of single SES, E-ZES or EES between January 1, 2007 and December 31, 2009 from the National Health Insurance claims database, Taiwan. Follow-up was through Decemb

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Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology

Randomized clinical trial comparing sodium picosulfate with mannitol on the preparation FOR colonoscopy in hospitalized patients Ensaio clínico randomizado comparando picosulfato de sódio com manitol no preparo para colonoscopia em pacientes hospitalizados

Suzana Müller, Carlos Fernando de Magalhães Francesconi, Ismael Maguilnik et al. · 2007 · Arquivos de Gastroenterologia

BACKGROUND: The cleansing of the colon for a colonoscopy exam must be complete so as to allow the visualization and inspection of the intestinal lumen. The ideal cleansing agent should be easily administered, have a low cost, and minimum collateral effects. Sodium picosulfate together with the magnesium citrate is a cathartic stimulant and mannitol is an osmotic laxative, both usually used for this purpose. AIMS: Assess the colon cleanliness comparing the use of mannitol and sodium picosulfate as well as evaluate the level of patient satisfaction, the presence of foam, pain, and abdominal dist

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Negative / Null Result ReportOpen accessMedicine

Obesity and Dyslipidemia

Feingold KR · 2000

Abnormalities in lipid metabolism are very commonly observed in patients who are obese. Approximately 60-70% of patients with obesity are dyslipidemic. The lipid abnormalities in patients who are obese include elevated serum TG, VLDL,…

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Negative / Null Result ReportOpen accessMedicine

Association of outpatient use of renin–angiotensin–aldosterone system blockers on outcomes of acute respiratory illness during the COVID-19 pandemic: a cohort study

Molly Moore Jeffery, Lucas Oliveira J e Silva, Fernanda Bellolio et al. · 2022 · BMJ Open

Objectives Evaluate the associations between patients taking ACE inhibitors and angiotensin receptor blockers (ARBs) and their clinical outcomes after an acute viral respiratory illness (AVRI) due to COVID-19.Design Retrospective cohort.Setting The USA; 2017–2018 influenza season, 2018–2019 influenza season, and 2019–2020 influenza/COVID-19 season.Participants People with hypertension (HTN) taking an ACEi, ARB or other HTN medications, and experiencing AVRI.Main outcome measures Change in hospital admission, intensive care unit (ICU) or coronary care unit (CCU), acute respiratory distress (ARD

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Negative / Null Result ReportOpen accessSurgery

Clinical Relevance of Preoperative Neutrophil to Lymphocyte and Platelet to Lymphocyte Ratio in Renal Cell Carcinoma

Engin Kölükçü, Şahin Kılıç, Doğan Atılgan et al. · 2018 · Journal of Urological Surgery

Objective:The association of preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with postoperative tumor stage and Fuhrman nuclear grade was investigated in patients with renal cell carcinoma (RCC).Materials and Methods:Data of 123 patients, who were operated due to RCC, in our clinic was analysed. NLR and PLR were evaluated in patients who were classified according to tumor stage (T1 and T2 low stage, T3 and T4 high stage) and Fuhrman nuclear grade (grade 1 and 2 low-grade, grade 3 and 4 high-grade). NLR and PLR were compared using Levene’s test between t

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Negative / Null Result ReportOpen accessPediatrics

A comparative study on the efficacy of two CD19/CD22 dual-targeting CAR-T strategies in children with relapsed/refractory B-cell acute lymphoblastic leukemia with PAX5 gene variations

LI Yue, XIE Zhiwei, TANG Yanjing, LI Benshang · 2026 · Linchuang erke zazhi

Objective Antigen escape, particularly CD19 loss, limits the efficacy of CD19-targeted chimeric antigen receptor T-cell (CAR-T) therapy in children with relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL). PAX5 gene variations have been shown to disrupt CD19 expression stability and increase relapse risk. This study aimed to compare the therapeutic efficacy of two CD19/CD22 dual-targeting CAR-T strategies, namely co-infusion versus bicistronic construct, in children with R/R B-ALL harboring PAX5 gene variations. Methods A retrospective analysis was conducted on the clinical dat

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Negative / Null Result ReportOpen accessDentistry

Genotoxicity effects of nano bioactive glass and Novabone bioglass on gingival fibroblasts using single cell gel electrophoresis (comet assay): An in vitro study

Mohammad Tavakoli, Ensiyeh Bateni, Mansour Rismanchian et al. · 2012 · Dental Research Journal

Background: The greater surface of bioactive glass nanoparticles presents an incomparable and promising feature similar to the biological apatite. Nanoparticles improve cellular adhesion, enhance osteoblast proliferation and differentiation, and increase biomineralization for periodontal regeneration and dental implants. Considering the fact that interaction between periodontal cells and bone graft materials are important for periodontal lesion regeneration, the present study was undertaken to investigate the genotoxicity of a novel synthesized nanoscale bioactive glass and compared it with No

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Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens

Optical diagnosis in still images of colorectal polyps: comparison between expert endoscopists and PolyDeep, a Computer-Aided Diagnosis system

Pedro Davila-Piñón, Pedro Davila-Piñón, Alba Nogueira-Rodríguez et al. · 2024 · Frontiers in Oncology

BackgroundPolyDeep is a computer-aided detection and classification (CADe/x) system trained to detect and classify polyps. During colonoscopy, CADe/x systems help endoscopists to predict the histology of colonic lesions.ObjectiveTo compare the diagnostic performance of PolyDeep and expert endoscopists for the optical diagnosis of colorectal polyps on still images.MethodsPolyDeep Image Classification (PIC) is an in vitro diagnostic test study. The PIC database contains NBI images of 491 colorectal polyps with histological diagnosis. We evaluated the diagnostic performance of PolyDeep and four e

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Negative / Null Result ReportOpen accessMedicine

Allergic sensitization does not influence advancement or survival in oral cancer

Lara Kakabas, Krzysztof Piersiala, Aeneas Kolev et al. · 2023 · Scientific Reports

Abstract A history of allergies has been said to be associated with a lower risk of head and neck cancer compared to the general population. However, it is not known whether having an allergic sensitization influences the prognosis and advancement of cancer disease. Thus, the aim of the study was to investigate the relationship between allergic sensitization and oral cancer advancement and patient survival. Allergen-specific IgE antibodies were investigated by ImmunoCAP™ Rapid in consecutive 80 patients with oral cancer. ImmunoCAP Rapid system tests a mix of representative inhalant allergens s

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Negative / Null Result ReportOpen accessMedicine

Origins of the obturator artery in Thai and Chinese

Damkoeng Purnindu · 2023 · Siriraj Medical Journal

Dissection of one-half of adult pelvis in 197 Thai and 44 Chinese cadavers disclosed that the obturator artery arose from the internal iliac and umbilical arteries in 34.9%, from the inferior gluteal artery in 10.4%, from the internal pudendal artery in 8.7%, from the superior gluteal - inferior gluteal trunk in 4.2%, from the inferior gluteal - internal pudendal trunk in 9.1%, from the inferior epigastric artery in 12.0%, from the external iliac artery in 1.2%, and from the superior gluteal and the inferior epigastric arteries in 0.4%. There were no statistically significant differences of fi

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Negative / Null Result ReportOpen accessAnesthesiology

Comparison of malnutrition screening tests in predicting postoperative complications in elderly patients with femur fracture

Orhan Kılıç, Murat Yaşar Özkalkanlı, Fulya Yılmaz et al. · 2022 · Ain Shams Journal of Anesthesiology

Abstract Background Malnutrition is an important and widespread problem in hospitalised elderly orthopaedic patients. It is an important predictor of morbidity and mortality and has been associated with an increased risk of complications. Although it is a common problem in the elderly, there is neither a universally accepted criterion for the diagnosis of malnutrition nor a screening tool accepted as the gold standard to detect patients at risk of malnutrition. There is still no consensus on which is the most recommended for screening hospitalised patients for nutritional risk. The aim of this

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Negative / Null Result ReportOpen accessDentistry

Correlation of CD10 immunoexpression and eosinophil count in stromal tissue as predictors of prognosis of squamous cell carcinoma of the oral cavity

Deece Patuti, Harmas Yazid Yusuf, Bethy Suryawathy Hernowo · 2010 · Padjadjaran Journal of Dentistry

Introduction: CD10 can also facilitate the ability of tumour metastasis by its ability to invade blood vessel walls.Correlation of CD10 immunoexpression and eosinophil count in stromal tissue as predictors of prognosis of squamous cell carcinoma of the oral cavity. Methods: This study was preceded by collecting data on squamous cell carcinoma of the oral cavity in the medical record and paraffin blocks in the Anatomy Pathology section of 15 samples with enlarged regional lymph nodes and 15 samples without enlargement of regional lymph nodes. Then two preparations were made, the first preparati

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Negative / Null Result ReportOpen accessMedicine

Correlation of body mass index and orthostatic hypotension in patients with hypertension on ACE inhibitor monotherapy

Tasić Danijela, Kovačević Zorana, Mitrović Miroslav et al. · 2021 · Scripta Medica

Background/Aim: Orthostatic hypotension (OH) is considered to be a drop in the systolic and diastolic blood pressure (> 20 mmHg; > 10 mmHg) 3 minutes from postural changes. The objective of this study was to analyse the correlation of body mass index (BMI) and OH during the treatment with trandolapril, as a single-drug treatment of hypertension. Methods: The study involved 255 patients (average age 54.3 ± 11.7; 54.1 % men) with poorly regulated hypertension, who were given trandolapril as a single-drug treatment. The patients were divided into two groups regarding stage of hypertension: first-

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