Negative / Null Result ReportMedicine
Pleau J, Tanguay N, Courtemanche Y et al. · 2025 · Maternal and child health journal
Objectives The objectives of this study are to describe cannabis use during pregnancy, identify associated factors, examine the associations between prenatal cannabis use and the cognitive, motor and language development of 2-year-old…
View details →Negative / Null Result ReportMedicine
Quaedflieg CWEM, Ashton SM, Beckers T et al. · 2025 · Journal of behavior therapy and experimental psychiatry
Fear is a universal experience and fuels our response to cope with threat. Persistent fear, after the threat is no longer present, is a central symptom seen in a number of clinical conditions. Exposure therapy, the most common treatment to…
View details →Negative / Null Result Report
van Berlo E · 2024 · Preprint
In this study, we investigated how spatial, temporal, and effort dimensions collectively influence reward discounting across different age groups. Using a 3D simulated environment, participants aged 7 to 77 chose between a nearby tree with…
View details →Negative / Null Result Report
Lazar R, Fazlali F, Dourte M et al. · 2024 · Preprint
Whether light exposure during the day reduces non-visual light effects later in the evening has not been studied in adolescents. We investigate whether afternoon-early evening (AEE) light interventions (130 lx, 2500 lx, 4.5 hours, compared…
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Vidal V, Pretel MR, Capurro L et al. · 2024 · Preprint
Abstract The application of neuroscience findings in educational settings offers promising opportunities to enhance academic performance. Adolescents, particularly affected by delayed sleep patterns due to early school start times, often…
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Molloy M, McLennan E, Fox S et al. · 2024 · Preprint
The gut microbiome is an important component of host health and function and is influenced by internal and external factors such as host phylogeny, age, diet, and environment. Monitoring the gut microbiome has become an increasingly…
View details →Negative / Null Result ReportOpen accessMedicine
Hidding M, van der Stouwe E, Rosema BS et al. · 2025 · Psychological medicine
Background Low self-esteem is an important and potentially modifiable risk factor for the development and outcome of psychotic disorders. The factors involved in low self-esteem in psychotic disorders are not yet fully understood. The…
View details →Negative / Null Result Report
Pascual LMM, Vusirikala A, Nemenman IM et al. · 2024 · Preprint
The changes in neural activity that underlie motor skill acquisition during development are unknown. Juvenile songbirds learn their songs by an imitative process, and after learning adults use a millisecond-precise spike timing code to…
View details →Negative / Null Result ReportMedicine
Tao Z, Fowler K, Trenga-Schein N et al. · 2025 · Journal of palliative medicine
Background: Historically, there have been perceptions that engagement with palliative care (PC) services may preclude potentially curative but high-risk operations. As such, we sought to investigate the relationship between specialty PC…
View details →Negative / Null Result ReportOpen accessMedicine
Harada S, Teraoka R, Kuroda N et al. · 2026 · Experimental brain research
This study investigated audiovisual integration in visual motion perception among both younger and older adults. Participants were asked to discriminate the visual motion direction of a random dot kinematogram in two experiments. The…
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Chung YH, Williams L, Brady TF et al. · 2024 · Preprint
Across many studies, verbal labels have been shown to significantly affect perceptual and cognitive processes. Here we ask whether verbal labels can also improve visual working memory performance by making objects more recognizable. In a…
View details →Negative / Null Result Report
Moore TM, Walker K, Tung E et al. · 2024 · Preprint
Depression and PTSD are prevalent psychiatric conditions that often co-occur and significantly impact quality of life. Ketamine has emerged as a promising rapid-acting treatment for both conditions, while traditional treatments like…
View details →Negative / Null Result Report
Andreassen M, Larsen EO, Mølmen KS et al. · 2024 · Preprint
Abstract Introduction: A positive relationship between physical exercise training and cognitive function in humans is well-established. However, knowledge of how resistance exercise training affects patients with chronic obstructive…
View details →Negative / Null Result ReportMedicine
Midilli B, Nurten A, Gürtekin B et al. · 2025 · Behavioural brain research
Antimuscarinic administration and food intake cause convulsions in mice and rats after fasting for 48 h or less. Increased M 1 and M 2 muscarinic receptor expression in brain regions during fasting, and reversal of changes by refeeding may…
View details →Negative / Null Result ReportOpen accessMedicine
Rothe J, Thiel T, Roessner V et al. · 2025 · BMC psychiatry
Background Autistic individuals often experience significant difficulties adapting to even slight changes in their routines. The COVID-19 pandemic created an uncertain situation marked by frequent changes in daily life, though some…
View details →Negative / Null Result ReportOpen accessMedicine
Honkanen J, Molnár K, Karhumaa T et al. · 2025 · Journal of endocrinological investigation
Purpose Thyroid surgery is performed for various indications, including goiter, suspected or diagnosed malignancy, and hyperthyroidism. While previous studies have focused on postoperative quality of life (QoL) improvements, limited data…
View details →Negative / Null Result ReportMedicine
Borghoff KA, Ounda AE, Swee ML et al. · 2025 · Clinical nephrology
Background and objectives Chronic kidney disease (CKD) is associated with increased cardiovascular risk, which may be mediated by vascular calcification. Based on evidence that bisphosphonates inhibit vascular calcification, we…
View details →Negative / Null Result ReportMedicine
Kuan HY, Chang CH · 2024 · Journal of physiological investigation
Abstract Stress is an adaptive response crucial for survival. However, chronic stress can lead to maladaptive behaviors and health issues. Prolonged stress reduces the flexibility of defensive coping behaviors. Previous studies have shown…
View details →Negative / Null Result ReportOpen accessMedicine
Nam J, Bellinger GC, Li J et al. · 2025 · JMIR cardio
Background Wearable activity monitors offer clinicians and researchers accessible, scalable, and cost-effective tools for continuous remote monitoring of functional status. These technologies can complement traditional clinical outcome…
View details →Negative / Null Result Report
van Berlo E, Hausfeld J, Engelmann JB et al. · 2024 · Preprint
In this study, we investigated how spatial, temporal, and effort dimensions collectively influence reward discounting across different age groups. Using a 3D simulated environment, participants aged 7 to 77 chose between a nearby tree with…
View details →Negative / Null Result Report
Angeletos Chrysaitis N, Seriès P · 2024 · Preprint
Bayesian studies of perception have documented how the brain learns the statistics of a new environment and uses them to interpret sensory information. Impairments in this process have been hypothesised to be central to autism spectrum…
View details →Negative / Null Result ReportOpen accessMedicine
Liu X, Zheng W, Hoon L et al. · 2026 · Npj mental health research
Smartphone-delivered interventions offer a scalable solution for university students experiencing depression, yet outcomes remain inconsistent. This study examined predictors of depression remission and response in the AI-enhanced Vibe Up…
View details →Negative / Null Result ReportOpen accessMedicine
Bakhshinejad JA, Watkins CM, Pelton LM et al. · 2026 · International journal of exercise science
The primary aim of this investigation was to examine the effects of three drop jumps (DJ) on mean velocity (m/s) of subsequent deadlifts at various percentages of 1 RM. A secondary exploratory aim was to evaluate whether protocol order,…
View details →Negative / Null Result ReportOpen accessMedicine
Lewandowski KE, Luo J, Yao B et al. · 2025 · Frontiers in psychiatry
Introduction Motivational impairments are a hallmark symptom of psychotic disorders. However, motivation is a multidimensional construct believed to be underpinned by different neural mechanisms and differentially impaired both between and…
View details →Negative / Null Result ReportMedicine
Cronin SK, Barnard AM, Dietz SJ et al. · 2023 · Journal of dairy science
It is possible that some of the systemic responses to subacute ruminal acidosis (SARA) may be caused by increased intestinal starch fermentation. The objective of this experiment was to evaluate the effect of abomasal infusion of up to 3 g…
View details →Negative / Null Result ReportMedicine
He JD, Parker JD · 2023 · British journal of clinical pharmacology
Aims To mediate its pharmacodynamic effects, glyceryl trinitrate (GTN) requires bioactivation, by which it releases nitric oxide or a nitric oxide moiety. The exact mechanism of GTN bioactivation remains uncertain. Mitochondrial aldehyde…
View details →Negative / Null Result ReportOpen accessMedicine
Alizo Vera V, Childs JE, Kim J et al. · 2025 · eNeuro
Histone deacetylase 3 (HDAC3) is one of the most highly expressed HDACs in the brain shown to be a negative regulator of long-term memory formation. HDAC3 has also been shown to be involved in cocaine-associated behaviors, demonstrated by…
View details →Negative / Null Result ReportMedicine
Sabino-Carvalho JL, Li S, Mekonnen E et al. · 2025 · Medicine and science in sports and exercise
Purpose Parasympathetic reactivation is essential for the rapid decrease in heart rate following exercise and delayed heart rate recovery (HRR) post-exercise is linked to poor clinical outcomes. Chronic kidney disease (CKD) is associated…
View details →Negative / Null Result ReportMedicine
Volpe LJ, Zugelder M, Kotarinos R et al. · 2023 · Urogynecology (Philadelphia, Pa.)
Importance Although pelvic floor physical therapy (PFPT) is effective in treating high-tone pelvic floor dysfunction (HTPFD), data on the mechanism of improvement are limited. Objectives This study aimed to compare squeeze intravaginal…
View details →Negative / Null Result Report
Thorudottir S, Asgeirsson AG, Sigurdardottir HM · 2024 · Preprint
Visual mental imagery, or the ability to “see” with the mind’s eye, varies substantially across individuals. This vividness ranges from aphantasia, where no mental images are experienced, to hyperphantasia, characterized by exceptionally…
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