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WASTE Journal

Browse the failure-mode index

20,253 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

The relationship between fall risk, trochanteric soft tissue thickness, and hip fracture risk in older adults.

Johannesdottir F, Aspelund T, Mahar S et al. · 2026 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Current fracture risk assessment does not directly include fall probability, despite the fact that most hip fractures resulting from falls. Additionally, the role of trochanteric soft tissue thickness (TST) in hip fracture risk remains…

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Negative / Null Result ReportMedicine

Preharvest application of Meyerozyma guilliermondii LMA-Cp01 biofungicide combined with sodium benzoate for eco-friendly management of anthracnose disease on mango fruit.

López-Cruz R, Ragazzo-Sánchez JA, Calderón-Santoyo M · 2026 · Archives of microbiology

In this study, mango fruit trees cv. Kent (Mangifera indica L.) grown in Nayarit, Mexico, during the 2024 and 2025 seasons were preharvest-treated with four applications of microencapsulated Meyerozyma guilliermondii LMA-Cp01 (0.4 g L⁻¹),…

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Negative / Null Result ReportMedicine

Protective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats.

Kharazmi K, Saroughi M, Khoshniat MT et al. · 2026 · Naunyn-Schmiedeberg's archives of pharmacology

Lead exposure is linked to various adverse effects on human health, including toxicity to multiple organs such as the kidneys, liver, and reproductive system. Lead induces its toxic effects through complex pathways, including mitochondrial…

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Negative / Null Result ReportMedicine

No Effect of a Single Session of Anodal Transcranial Direct Current Stimulation on Exercise-Induced Hypoalgesia in Knee Osteoarthritis: A Randomized Cross-Over Trial.

Toomey D, Lewis G, Rashid U et al. · 2026 · Neuromodulation : journal of the International Neuromodulation Society

Background Exercise induces short-term pain relief (exercise-induced hypoalgesia, EIH), but this response is often blunted in people with knee osteoarthritis (OA). Transcranial direct current stimulation (tDCS) has been proposed as a…

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Negative / Null Result Report

Contrasting the classic effect of reward on attentional priority maps: Behavioral evidence for an attentional gating of spatially-specific reward signals

Beffara B, Hadj-Bouziane F, Ben Hamed S et al. · 2026 · Preprint

The control of selective visuo-spatial attention is known to rely on multiple signals, including reward. While most attention control signals are well acknowledged to interact with each other, the case of reward has led to mixed findings…

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Negative / Null Result ReportMedicine

Therapeutic and Prophylactic Effects of the Surfactant Protein D Mimetic CGSPS18 Against Schistosoma mansoni in Biomphalaria alexandrina and Mice.

El-Karim RMG, Ali REM, Habib MR et al. · 2026 · Acta parasitologica

Bachground Schistosomiasis remains difficult to control due to persistent transmission via freshwater snails and reliance on praziquantel (PZQ) as the primary treatment. Novel adjunctive strategies targeting multiple stages of the parasite…

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Negative / Null Result Report

Comparative Evaluation of Non-HDL Cholesterol and the Triglyceride-Glucose Index for Predicting Acute Myocardial Infarction Risk in a Nepalese Hospital Population: A Cross-Sectional Study

Gupta BK, Pandey R, Thapa N et al. · 2026 · Preprint

Abstract Background Myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide, with South Asian populations facing a disproportionately high burden. In Nepal, the incidence of MI has been rising, and recent…

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Negative / Null Result ReportMedicine

Can transcranial Direct Current Stimulation enhance the efficacy of a rehabilitative intervention for the treatment of Freezing of Gait in Parkinson's disease? A double-blind, randomized controlled study.

Madrid J, Batzianouli E, Rutz D et al. · 2026 · Journal of Parkinson's disease

BackgroundFreezing of gait (FOG) in Parkinson's disease (PD) is a major cause of disability and falls and often responds incompletely to conventional therapy. Rehabilitative interventions including cognitive strategies and sensory cueing…

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Negative / Null Result ReportMedicine

A Combinatorial Strategy for Peripheral Nerve Repair Utilizing 3D-Printed Collagen Nerve Guidance Conduits and Photobiomodulation Therapy: A Pilot Study in a Rat Sciatic Nerve Transection Model.

Fellin CR, Steiner RC, Buchen JT et al. · 2026 · Photobiomodulation, photomedicine, and laser surgery

Background Nerve guidance conduits (NGCs) are a clinically approved option for peripheral nerve repair but remain ineffective compared with autograft "gold standard" treatment options. A combinatorial approach to conduit-based peripheral…

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Negative / Null Result ReportMedicine

Full-fat meal, defatted meal, oil and chitin from black soldier fly in low and high soybean-based diets on growth performance and nutrient retention of rainbow trout

Riesenbach IC, Tsomik G, Chiasson M et al. · 2026 · Aquaculture.

Insects, such as black soldier flies (BSF), have garnered attention in the aquaculture industry as a sustainable protein and lipid alternative to fishmeal and fish oil. However, research is lacking on which components of BSF improve fish…

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Negative / Null Result Report

Metabolic interoceptive rewards shape affect, but not action

Fleming HA, Whines A, Whelehan P et al. · 2025 · Preprint

Central to survival is our ability to learn that the sensory properties of food are associated with metabolic interoceptive signals (e.g., changing blood glucose). These signals influence cognition and brain activity, shaping the hedonic…

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Negative / Null Result ReportMedicine

Respiratory Biofeedback Training as an Adjunct Intervention in Pulmonary Rehabilitation for Late-Stage COPD: A Pilot Trial.

Lagravinese G, Castellana G, Genco M et al. · 2026 · Applied psychophysiology and biofeedback

Chronic obstructive pulmonary disease (COPD) is associated with persistent dyspnea, reduced functional capacity, and significant cognitive and affective impairments. Pulmonary rehabilitation improves the physical and psychological…

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Negative / Null Result ReportMedicine

Evaluating the utility of ICG-based NIR imaging for small intestine neuroendocrine tumors: Challenges and the need for tumor-specific tracers.

Dalmeijer SWR, Zweedijk BE, Boldewijn DF et al. · 2026 · Surgical oncology

Purpose Accurate intraoperative localization of small intestinal neuroendocrine tumors (SI-NETs) remains a surgical challenge, with standard staging protocols frequently missing small primary or metastatic lesions. ICG has shown utility in…

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Negative / Null Result ReportMedicine

Double Knockdown of the Androgen Receptor Target Genes DKK1 and SFRP1 Does Not Potentiate the Hair Growth-Promoting Effect of SFRP1 Silencing in Healthy Human Hair Follicles Ex Vivo.

Broadley D, Le Riche A, Yu Y et al. · 2026 · International journal of molecular sciences

Androgen receptor (AR) signaling plays a key role in male pattern baldness. We investigated whether targeting Dickkopf 1 ( DKK1 ) and Secreted frizzled-related protein 1 ( SFRP1 ), two AR-regulated genes, offers a novel therapeutic…

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