Negative / Null Result ReportOpen accessDermatology
Fadime Mutlu İçduygu, Isil Deniz Oguz, Egemen Akgun et al. · 2026 · Dermatology Practical & Conceptual
Introduction: Psoriasis, a widespread inflammatory cutaneous disease, is driven by an interplay of genetic and environmental risk factors. miR-155 and miR-146a have been implicated in the regulation of inflammatory pathways. Objectives: In the current study, we examined the association between miR-155 rs767649 and miR-146a rs2910164 variants and the predisposition to psoriasis and psoriatic arthritis. Methods: A total of 544 individuals, including 284 psoriasis cases (68 with psoriatic arthritis) and 260 controls, were enrolled in the present study. Real-time polymerase chain reaction (qPCR) m
View details →Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Feng-Hang Chang, Alan M. Jette, Mary D. Slavin et al. · 2018 · BMC Musculoskeletal Disorders
Abstract Background The intent of this study was to examine and compare the ability to detect change of two patient reported outcome (PRO) instruments that use a computerized adaptive test (CAT) approach to measurement. The Patient Reported Outcomes Measurement Information System (PROMIS®) Physical Function scale is a generic PRO, while the Osteoarthritis Computerized Adaptive Test (OA-CAT) is an osteoarthritis-specific PRO. Methods This descriptive, longitudinal study was conducted in a community setting, involving individuals from the greater Boston area. Inclusion criteria: age > 50, self-r
View details →Negative / Null Result ReportOpen accessMining engineering. Metallurgy
Yutaka ITO, Masato TAKEUCHI, Shuto MIKAMI et al. · 2020 · Journal of MMIJ
Productivity, safety and its improvement is also an integral part of a good mining operation. In recent times, due to constraints on time and cost, it has become increasingly harder to conduct training and safety inductions at mine sites. For the purpose of overcoming these limitations, the use of virtual reality (VR) is proposed for mining education and training. VR has already been introduced in the education and training of miners overseas, and quantitative studies on the effects of using VR for miner's education and training have been made. However, Japan has only one such application
View details →Negative / Null Result ReportOpen accessMedicine
Oliver Hendricks, Mikkel Østergaard, Susanne Juhl Pedersen et al. · 2026 · RMD Open
Introduction Evidence of treat-to-target strategies including secukinumab dose escalation in patients with axial spondyloarthritis (axSpA) remains limited. We investigated the effect of a treat-to-target approach aiming for Axial Spondyloarthritis Disease Activity Score (ASDAS) remission, assessed by clinical and MRI outcomes over 24 weeks.Methods TRACE was a multicentre study including biologic-naïve patients with active axSpA. Sixteen weeks after secukinumab 150 mg initiation, patients in ASDAS remission (<1.3)(week 16 remitters) continued the same dose, while non-remitters (week 16 non-remi
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Zhang X, Liu X, Wang L et al. · 2026 · Preprint
Abstract Objective Breast cancer is a prevalent malignant disease among women. Currently, the primary clinical treatment strategies involve classifying breast cancer based on the expression of Ki67, estrogen receptor (ER), progesterone…
View details →Negative / Null Result ReportOpen accessMedicine
Csontos J, Brown N, Edwards A et al. · 2026 · BMC public health
BACKGROUND: Adults (age 18–64 years) are recommended 150–300 min of moderate-to-vigorous or 75–150 min of vigorous-intensity physical activity per week. Irrespective, the number of women not meeting recommended physical activity is 5%…
View details →Negative / Null Result ReportOpen accessMedicine
Corcoran E, Samuel Z, Force A et al. · 2026 · Orthopaedic journal of sports medicine
Background Osteochondral defects (OCDe) of the knee in pediatric patients can significantly impact long-term joint function. This study aimed to evaluate the impact of lesion size on patient characteristics, treatment decisions, and…
View details →Negative / Null Result ReportOpen accessMedicine
Castro M, Carrasco-Zambrano N, Pezo F et al. · 2026 · Frontiers in veterinary science
The routine prophylactic use of antibiotics in sperm preservation for reproductive biotechnologies poses increasing concerns due to its potential role in promoting antimicrobial resistance. Therefore, developing storage systems that…
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Abebe GM, Demissie WM, Zewdie MC · 2026 · Preprint
Abstract Mechanization has immense potential to improve agricultural productivity and overall production, while crop–livestock diversification plays a crucial role in enhancing nutrition security; however, the combined effects of…
View details →Negative / Null Result ReportOpen accessMedicine
Belnap MA, Witkiewitz K, Schacht JP et al. · 2026 · Alcohol, clinical & experimental research
Background The U.S. Food and Drug Administration (FDA) recommends a minimum duration of 6 months for randomized controlled trials (RCTs) evaluating pharmacotherapies for alcohol use disorder (AUD). The relationship between trial length and…
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Caldana M, Rusconi E · 2026 · Preprint
Olfaction is one of our most archaic senses but its central mechanisms are lesser known than those of other senses. In this work, we address a possible link between olfactory stimuli and mental spatial representations. Although olfactory…
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Ajit A · 2026 · Preprint
Abstract Automated diabetic retinopathy (DR) screening achieves specialist-level accuracy on curated benchmarks, yet subgroup performance disparities remain poorly understood mechanistically. We introduce the Optic Disc Colour Ratio…
View details →Negative / Null Result ReportMedicine
Orihuela CA, Dotson B, Sharff A · 2026 · Journal of health psychology
Food insecurity continues to be a critical social determinant of health in the United States. Existing research on food insecurity within clinical populations has focused on specific health conditions. However, this approach may limit the…
View details →Negative / Null Result ReportMedicine
Noll D, Stapleton P, O'Callaghan M · 2026 · BJU international
Objective To calculate additional information from urological trials which do not report statistically significant results, and assess whether language manipulation is used when such studies were reported. Materials and methods Many…
View details →Negative / Null Result ReportMedicine
Cai X, Zhou L, Lü M et al. · 2026 · Chaos (Woodbury, N.Y.)
We study resilience in collective behaviors of "next-generation reservoir computers" in terms of transmitted signal distortion. Specifically, we introduce an interactive communication scheme and achieve synchronization between two…
View details →Negative / Null Result ReportOpen accessMedicine
Thepa TLP, Tyasi TL, Ng'ambi JW · 2026 · Tropical animal health and production
Pre-weaning mortality is a challenge for goat production systems, especially under extensive management. The study investigated the effect of the litter size and birth weight on the pre-weaning survivability of Kalahari Red goat kids. A…
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Whitmore N, Kim M, Chua P et al. · 2026 · Preprint
Abstract Interoception–the capacity to sense and process internal bodily signals–is strongly linked to emotional experience and mental health, but whether amplifying access to bodily signals causally improves mental well-being remains…
View details →Negative / Null Result ReportMedicine
Ali M, Salehnejad R, Kawalek P · 2026 · The International journal of health planning and management
This study investigates the role of complementary clusters of human resource management (HRM) practices in explaining the persistent productivity variations across English NHS hospitals. While prior research has highlighted the importance…
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Mofokeng TS, Okoro CS · 2026 · Preprint
We examine whether board activity, board size, board independence, and board tenure are associated with the performance of South African REITs from 2013 to 2025. We assess whether these attributes translate into measurable performance…
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Pramitra B, Al Musadieq M, Afrianty TW et al. · 2026 · Preprint
This study aims to examine the influence of networking capabilities and transformational organizational characteristics on digital adoption, as well as its impact on port performance at container ports in Indonesia. This study also…
View details →Negative / Null Result ReportMedicine
Atay S, Kurt A, Dağ OD et al. · 2026 · Journal of oral science
Purpose This study aimed to evaluate the effects of scan body splinting material types and heights on scanning accuracy and duration for a completely edentulous mandible. Methods Scan bodies on multi-unit abutments were splinted at heights…
View details →Negative / Null Result ReportMedicine
Talhelm J, Srivastava S, Ostrander J et al. · 2026 · Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
Falls by subjects riding a ski lift while in transit are rare but can cause significant injury. Falls can occur at variable heights and can occur to small children to adults of both genders. The current study was designed to investigate…
View details →Negative / Null Result ReportMedicine
Clemens NH, Boucher AN, Vaughn S et al. · 2026 · Journal of learning disabilities
Students in grades 2 through 4 with significant word reading difficulties were randomly assigned to one of two 10-week interventions. In the Dual Treatment condition, decoding instruction emphasized regularity in spelling-sound…
View details →Negative / Null Result ReportMedicine
Kaba M, Eyüboğlu GB, Karadas M · 2026 · Polymers
This study aimed to assess the effect of etching protocols on the bonding performance of three universal adhesives to dentin under different aging conditions. Specimens were obtained from human molars and randomly allocated to 6 groups ( n…
View details →Negative / Null Result ReportOpen accessMedicine
Alfakih A, Nadeau NJ, Watt PJ · 2026 · Ecology and evolution
Widely distributed animals may exhibit substantial plastic physiological, morphological and behavioural responses to environmental changes. One such extraordinary form of plasticity is colour change, which varies substantially among most…
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Ofori I · 2026 · Preprint
Abstract In the current dynamic and competitive business landscape, firms are under increasing pressure to improve their cost efficiency while simultaneously embracing sustainable supply chain practices. The main objective of the study was…
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Suwanlee S, Kamsaenrat W, Pimvong P et al. · 2026 · Preprint
Abstract Moringa oleifera Lam. leaves are rich in nutrients and possess high levels of antioxidant compounds, demonstrating potential as a functional feed ingredient for promoting animal health and productivity. However, Moringa oleifera…
View details →Negative / Null Result ReportMedicine
Sariali̇oğlu A, Oluç T · 2026 · BMC psychology
Background Blood sampling is one of the invasive procedures in a hospital setting that can cause fear, anxiety, and stress in children. Aim The study aimed to determine the effect of the Liquid Motion Bubbler Timer Soothing Sensory Toy on…
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Yidana P, Bangase EA, Billa G · 2026 · Preprint
Abstract Despite the growing global discourse on alternative credentials such as micro-credentials and skill-based certifications, empirical evidence on their influence on demand for traditional higher education in African contexts remains…
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SAHIN D · 2026 · Preprint
Abstract This study examines the motivational factors shaping ısers’ continuance intention toward generative artificial intelligence (GAI) by integrating the Uses and Gratifications theory (U&G) with the Unified Theory of Acceptance and…
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