Genetic Polymorphisms of miR-146a and miR-155 in Psoriasis and Psoriatic Arthritis: Evidence from a Turkish Case-Control Study
Fadime Mutlu İçduygu; Isil Deniz Oguz; Egemen Akgun; Burak Aksan; Sevgi Kulakli; Ebru Alp · 2026 · Dermatology Practical & Conceptual
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Abstract
Introduction: Psoriasis, a widespread inflammatory cutaneous disease, is driven by an interplay of genetic and environmental risk factors. miR-155 and miR-146a have been implicated in the regulation of inflammatory pathways. Objectives: In the current study, we examined the association between miR-155 rs767649 and miR-146a rs2910164 variants and the predisposition to psoriasis and psoriatic arthritis. Methods: A total of 544 individuals, including 284 psoriasis cases (68 with psoriatic arthritis) and 260 controls, were enrolled in the present study. Real-time polymerase chain reaction (qPCR) m
Abstract by Fadime Mutlu İçduygu; Isil Deniz Oguz; Egemen Akgun; Burak Aksan; Sevgi Kulakli; Ebru Alp, Dermatology Practical & Conceptual (2026) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.5826/dpc.1601a5977