Negative / Null Result ReportOpen accessAnimal culture
S. McCabe, N. McHugh, N.E. O’Connell et al. · 2020 · Animal
Feed costs account for the largest proportion of direct cost within suckler beef production systems. By identifying the cow type with enhanced capability of converting grazed herbage to beef output across lactations, suckler cow systems would become more efficient and sustainable. The objective of this study was to estimate grass DM intake (GDMI) and production efficiency among lactating suckler cows of diverse genetic merit for the national Irish maternal index (Replacement Index) which includes cow efficiency components such as milk yield and feed intake. Data from 131 cows of diverse geneti
View details →Negative / Null Result ReportOpen accessAgriculture
Hassan Toama Mohamed, Ali Sami Amen · 2012 · Al-Qadisiyah Journal For Agriculture Sciences
The present study aimes to examining the effect of the ethanolic extract of Melilotus officinalis flowers on bleeding time ,WBC and RBC count .Total number in males and females adult rabbit eighteen, (9 males and 9females ) are randomly divided into three equal groups (3 males and 3females per group). The first (control) is drenched normal saline while the second and third groups are drenched the ethanolic extracted (20 and 50mg/ml/kg of B.W) for 24 hours. The results reveal significant increase in bleeding time in third group followed by the second group compared with the control while RBC an
View details →Negative / Null Result ReportOpen accessVeterinary medicine
İsmail Gökçe Yildirim, Ece Koc Yildirim, Firuze Turker Yavas · 2025 · Slovenian Veterinary Research
Artificial lighting plays a crucial role in regulating the maturation of the reproductive system of birds during puberty and thus affects their reproductive capacity. The aim of this study was to investigate the morphometric effects of the use of different coloured light-emitting diodes (LEDs) on the gonads of male and female Japanese quail (Coturnix coturnix japonica). The experimental groups were also examined with regard to egg count, weight, fertility and hatchability. A total of 240 quails of mixed sex were subjected to three different light colours, namely white, green and blue LEDs. The
View details →Negative / Null Result ReportOpen accessPsychology
Weiping Yang, Weiping Yang, Ao Guo et al. · 2018 · Frontiers in Psychology
In older adults, cognitive abilities, such as those associated with vision and hearing, generally decrease with age. According to several studies, audio-visual perceptual training can improve perceived competence regarding visual and auditory stimuli, suggesting that perceptual training is effective and beneficial. However, whether audio-visual perceptual training can induce far-transfer effects in other forms of untrained cognitive processing that are not directly trained in older adults remains unclear. In this study, the classic P300 component, a neurophysiological indicator of cognitive pr
View details →Negative / Null Result ReportOpen accessProbabilities. Mathematical statistics
Ilya Zulaikha Zulkifli, Nor Faezah Mohamad Razi, Nor Hazlina Mohammad et al. · 2024 · Journal of Computing Research and Innovation
Over recent semesters, the increasing failure rates in STA108 have raised concerns about this course's teaching and learning environment. This issue has prompted an investigation into potential contributing factors, focusing on three main objectives: examining the students’ association between gender and MAT133, exploring the relationship between students’ achievements in MAT133 and their Mathematics grades in the Sijil Pelajaran Malaysia (SPM), and assessing the association between STA108 results and their Mathematics grades in the Sijil Pelajaran Malaysia (SPM). The respondents completed 329
View details →Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Deby Mukendi, Jean-Roger Lilo Kalo, Pascal Lutumba et al. · 2021 · BMC Infectious Diseases
Abstract Background The epidemiology of human cysticercosis and neurocysticercosis, caused by the larval stage of the pork tapeworm Taenia solium, is not well known in the Democratic Republic of Congo (DRC). Within a multicenter etiological and diagnostic study conducted by the NIDIAG consortium (“Better Diagnosis for Neglected Infections”) and investigating several challenging syndromes, we consecutively evaluated from 2012 to 2015 all patients older than 5 years presenting with neurological disorders (neurology cohort) and with fever > 7 days (persistent fever cohort) at the rural hospital o
View details →Negative / Null Result ReportOpen accessMedicine
Ayoola Ibifubara Aiyegbusi, Bosede Abidemi Tella, Ganiyat Adebanke Sanusi · 2020 · Nigerian Postgraduate Medical Journal
Background: Achilles tendinopathy (AT) is one of the most frequently reported ankle and foot overuse injuries. Prior studies have reported altered biomechanical variables of the lower limb as risk factors for the prevalence and severity of AT in athletes, especially in Caucasians, but there are few reports on African elite athletes. Because it is established that anthropometric and biomechanical values vary with racial disposition, this study was designed to investigate the association between selected physical and biomechanical variables of the lower limb and the prevalence and severity of AT
View details →Negative / Null Result ReportOpen accessMedicine (General)
Ammar Kadhim Alzubaidi, Farah Abdulwahab Al-Saadi, Amer Qani Alagele · 2025 · Indonesian Biomedical Journal
BACKGROUND: Many genetic factors are known to be related to osteoporosis, and currently the role of the glucagon-like peptide-1 receptor (GLP-1R) gene in bone health has been studied intensively. Some variation of this gene, such as rs1042044 and rs6458093, are known to be linked to metabolic diseases and lower bone mineral density, however their specific contribution to osteoporosis remains largely unexplored. Therefore, this study was conducted to investigate the combined genotypic effect of rs1042044 and rs6458093 as a genetic risk factor for osteoporosis in postmenopausal Iraqi women. METH
View details →Negative / Null Result ReportOpen accessMedicine
Maryam Rad, Arash Shahravan, Ali Akbar Haghdoost · 2017 · Journal of Oral Health and Oral Epidemiology
BACKGROUND AND AIM: Foods containing carbohydrates have a major effect on the pathogenesis of dental caries. There is a direct correlation between frequency of consumption of foods containing sugar and dental caries. The purpose of this study was to evaluate the dietary patterns of 12-year-old children and their awareness about the effect of diet on oral health in Iran. METHODS: A cross-sectional survey was conducted on 1554 children aged 12 years in 5 provinces in Iran. Subjects were selected based on a multistage stratified cluster random sampling procedure. Data were collected by a cultural
View details →Negative / Null Result ReportOpen accessMedicine
Amrita S Kumar, A Geetha, Jim Joe et al. · 2021 · Journal of Clinical and Diagnostic Research
Introduction: Blood donation is one of the most significant contributions that a person can make towards the society. A donor generally donates maximum 450 mL of blood at the time of donation. If 450 mL of blood is taken in a donation, men lose 242±17 mg and women lose 217±11 mg of iron. Hence, adequate iron stores are very important in maintenance of the donor’s health. Aim: To assess the influence of frequency of blood donation on iron levels of blood donors by estimating Haemoglobin (Hb) and other blood indices which reflect iron status of blood and serum ferritin which reflects body iron s
View details →Negative / Null Result ReportOpen accessNursing
Esmire Tërshnjaku Sadiku, Lence Aleksovska Velickovska, Samire Beqaj et al. · 2026 · Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija
Background. Down syndrome (DS) is associated with delayed gross motor development, and vitamin D deficiency is frequently reported in this population. However, evidence regarding the relationship between vitamin D status and motor development in children with DS is limited. Aim. To examine the association between serum 25-hydroxyvitamin D [25(OH)D] levels and gross motor development in children with DS. Methods. This analytical cross-sectional study included 33 children with DS (13 females and 20 males) aged 1.00–6.56 years (mean age 2.53 ± 1.06 years). Gross motor development was assessed usi
View details →Negative / Null Result ReportOpen accessMedicine
Giuseppe Carruba, Maria Luisa Calagna, Ildegarda Campisi et al. · 2022 · Diseases
This paper presents a multi-professional integrated approach toward the recognition and management of the nutritional and psychological needs of cancer patients. In particular, the patients undertook a multi-professional, multistep process that included the collection of both personal and clinical data, the evaluation of anthropometric measures, nutritional status and psychometric indices, and an ensuing personalized nutritional prescription and psychological support, ultimately leading to combined nutritional and psychological interventions to control their adherence to a nutritional program
View details →Negative / Null Result ReportOpen accessMedicine
Davis C Woodworth, Adelle Dagher, Adam Curatolo et al. · 2018 · PLoS ONE
The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has yielded neuroimaging and urinary biomarker findings that highlight unique alterations in brain structure and in urinary proteins related to tissue remodeling and vascular structure in patients with Urological Chronic Pelvic Pain Syndrome (UCPPS). We hypothesized that localized changes in diffusion tensor imaging (DTI) measurements might be associated with corresponding changes in urinary protein levels in UCPPS. To test this hypothesis, we created statistical parameter maps depicting the linear corre
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Ji-Young Lee, Hae In Cho, Heejin Kimm · 2024 · European Journal of Breast Health
Objective: There have been inconsistencies in the evidence for a role of dietary patterns in the development of breast cancer. In this study, we used a large-scale cohort [Korean Cancer Prevention Study-II (KCPS-II)] to examine the association between dietary patterns and breast cancer risk in Korean women. Materials and Methods: The dietary patterns of 14,807 women from the KCPS-II were derived by factor analysis and 135 cases of breast cancer were diagnosed during the follow-up period. Cox proportional models were used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) fo
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Lívia Beraldo de LIMA, André MALBERGIER, Priscila Dib GONÇALVES et al. · 2025 · Arquivos de Gastroenterologia
ABSTRACT Background: Hepatitis C virus (HCV) infection remains a significant public health concern. Behavioral factors such as alcohol use and psychiatric comorbidities, particularly depression, may influence disease progression and eligibility for antiviral treatment. Objective: To assess the prevalence and clinical impact of current alcohol consumption in patients with chronic HCV infection eligible for treatment with direct-acting antivirals (DAAs), and to explore its associations with depressive symptoms and clinical characteristics. Methods: This was a cross-sectional study including 109
View details →Negative / Null Result ReportOpen accessMedicine
Hana Wakasa, Satoshi Sunohara, Takashi Kimura et al. · 2025 · PLoS ONE
Obesity is a growing global health concern and has been associated with increased mortality from various cancer types, including hematological malignancies. However, evidence for this association in Asian populations, particularly among Japanese adults, remains limited. Thus, this study aimed to examine the association between obesity and mortality due to hematological malignancies. Data from 97,073 participants in the Japan Collaborative Cohort (JACC) Study were analyzed. The participants were followed for a mean duration of 17 years. Body mass index (BMI) was calculated using self-reported h
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Maha M. AlRasheed · 2022 · Saudi Pharmaceutical Journal
Background: The role of thyroid-stimulating hormone in the pathogenesis of thyroid cancer is not yet fully explored. This study aimed to evaluate the role of the TSH-β polymorphism in thyroid cancer in a Saudi cohort. Methods: A prospective case-control study was conducted on 507 patients with differentiated thyroid carcinoma and compared them with 560 controls of Saudi origin. The association of two variants, the rs201857310, and rs7530810, in the TSH-β gene with thyroid cancer risk as well as thyroxine dose, were evaluated. Results: The rs201857310_A > G [OR: 0.50 (95 % CI: 0.35–0.71); P < 0
View details →Negative / Null Result ReportOpen accessNursing
Z Gharehboghlou, M Adib-Hajbaghery, M Hajimohammad Hoseini · 2016 · نشریه پرستاری ایران
Abstract Background & Aim: Depression is the fourth leading cause of community disability in the world and it has high prevalence among students. Since spirituality is positively associated to physical and mental health, this study aimed to determine the relationship of spiritual well-being and depression among nursing students in Qom and Kashan Universities of Medical Sciences. Materials & Methods: This cross-sectional study was conducted on nursing students of Kashan and Qom Universities of Medical Sciences. Using a two-stage sampling method, 250 nursing students were randomly selected. Data
View details →Negative / Null Result ReportOpen accessAnesthesiology
Mayureshkumar Pareek, Vandana Parmar, Jigisha Badheka et al. · 2018 · Indian Journal of Anaesthesia
Background and Aims: Nurses should have cardiopulmonary resuscitation (CPR) knowledge and skills to be able to implement effective interventions during in-hospital cardiac arrest. The aim of this descriptive study was to assess mortality impact after nurses' CPR training with pre-CPR training data at our institute. Methods: Training regarding CPR was given to nurses, and CPR mortality 1-year before basic life support (BLS) and advanced cardiac life support (ACLS) training were collected and compared with post-training 1-year CPR mortality. Results: A total of 632 adult patients suffering in-ho
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Elahe Kamali, Simin Hemmati, Forouzan Safari et al. · 2015 · The International Journal of Biological Markers
Numerous epidemiological studies have evaluated the association between transforming growth factor beta receptor type 1 ( TGFBR1 ) polymorphisms and the risk of cancer; however, the results remain inconclusive and controversial. To determine the association between breast cancer risk and the *6A polymorphism of the TGFBR1 gene, a case-control study of 280 breast cancer patients and 280 controls was performed in Iranian women. Our study demonstrates that women who carry the TGFBR1*6A allele are at lower risk of developing breast cancer. The highest protection against breast cancer was observed
View details →Negative / Null Result ReportOpen accessPublic aspects of medicine
A Aleyasin, M Ghazanfari, M Houshmand · 2010 · Iranian Journal of Public Health
"nBackground: Leber hereditary optic neuropathy (LHON) is an inherited form of bilateral optic atrophy leading to the loss of central vision. The primary cause of vision loss is mutation in the mitochondrial DNA (mtDNA), however, unknown secon­dary genetic and/or epigenetic risk factors are suggested to influence its neuropathology. In this study folate gene polymor­phisms were examined as a possible LHON secondary genetic risk factor in Iranian patients."nMethods: Common polymorphisms in the MTHFR (C677T and A1298C) and MTRR (A66G) genes were tested in 21 LHON pa
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Jessica McIntyre, Rahaba Marima, Babatunde Alabi et al. · 2026 · Onco
Background: Cervical cancer is the second most prevalent malignancy among South African women, with high-risk human papillomavirus (HPV) infection as a critical risk factor. HPV plays a central role in cervical carcinogenesis, particularly in high-grade squamous intraepithelial lesions (HSIL). Increased programmed death ligand 1 (PD-L1) expression has been implicated in cervical carcinoma tumorigenesis. Using immunohistochemistry, this study investigated the correlation between high-risk HPV-driven cervical intraepithelial neoplasia (CIN) and PD-L1 expression. Methods: An analytical cross-sect
View details →Negative / Null Result ReportOpen accessFinance
Sayyede Elnaz Afzaliyan Boroujeni, Abdolmajid Abdolbaghi Ataabadi, Naser Khani · 2025 · Mathematics and Modeling in Finance
The present study aims to assess the impact of implied volatility (IV) extracted from call option prices on abnormal stock returns. IV, as a critical market volatility index, plays an essential role in explaining investor behavior. The Black-Scholes model was used to extract IV, applying Brent’s method due to the absence of an explicit closed-form solution. In addition, daily call option trading data from the Tehran Stock Exchange (TSE) were utilized during 2016-24. Further, quantile multivariate regression, along with wild bootstrap resampling (1,000 repetitions), was employed for model estim
View details →Negative / Null Result ReportOpen accessMedicine
Vivek Nagappa, Akhila Bhandarkar · 2025 · Journal of Family Medicine and Primary Care
Background: New research points to a complicated relationship between gallstone disease (GSD), thyroid function, and lipid profiles. To better understand how to prevent and treat GSD, this study will look at how common thyroid abnormalities are among people with the diagnosis, as well as any dyslipidemias that may be present. Material and Methods: This is a cross-sectional observational study worked out at a tertiary care hospital in southern India’s Department of General Surgery. We enrolled 60 persons with a GSD diagnosis. We divided patients with only gallstones and gallstones with common b
View details →Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Peipei Liu, Guoqing Dong, Mingzhu Li et al. · 2026 · Frontiers in Endocrinology
ObjectiveTo investigate the association between estrogen receptor β (ERβ) gene RsaI (rs1256049) and AluI (rs4986938) polymorphisms and the risk of idiopathic central precocious puberty (ICPP) in girls, and to provide potential molecular genetic references for early risk prediction and individualized management of ICPP.MethodsA total of 100 girls with ICPP from the Pediatric Endocrinology Clinic and Inpatient Ward of Shenzhen Maternity & Child Healthcare Hospital were enrolled, and 100 agematched healthy girls undergoing routine physical examinations during the same period served as controls. T
View details →Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Xingquan Zhao, Qian Zhang, Shengyun Chen et al. · 2025 · BMJ Open Diabetes Research & Care
Introduction The effects of different glucose metabolic states and diabetes-controlled status on asymptomatic carotid atherosclerosis has not been well investigated. Herein, we aimed to investigate the association of different diabetes status with asymptomatic carotid plaques and carotid intima–media thickness (CIMT).Research design and methods 4752 participants aged over 40 years, free of stroke or myocardial infarction, from the China National Stroke Screen Survey programme were enrolled. Carotid plaque and CIMT were assessed using duplex ultrasonography. Logistic regression analysis was use
View details →Negative / Null Result ReportOpen accessSports medicine
Joshua Choe MS, Saji Azerf MD, Pamela Lang MD · 2022 · Orthopaedic Journal of Sports Medicine
Background: The COVID-19 pandemic and related lockdowns in 2020 negatively impacted high school students, with increased depression and anxiety especially in athletes who participated in team sports. For adolescents with disabilities, physical activity provides physical and mental health benefits; however, the impact of COVID-19 related adaptive sports cancellations have not been thoroughly investigated. Hypothesis: Adaptive athletes with lower activity levels during a period of COVID-19 related restrictions will have worse scores of depression, anxiety, and quality of life. Methods: Instituti
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Salustiano Gomes Lins · 1971 · Arquivos de Neuro-Psiquiatria
Inicialmente é feita breve exposição dos cinco principais tipos de atividade lenta posterior descritas na literatura eletrencefalográfica: variedade lenta do ritmo alfa, ritmo theta posterior, ondas lentas posteriores a 4 hertz, ritmo delta associado ao pequeno mal e ondas Pi. Em seguida o autor expõe seus achados, baseado num material clínico composto por 760 pacientes, colhidos ao acaso, dos dois sexos e com idades variáveis entre 5 e 24 anos. Excetuando a variedade lenta do ritmo alfa, um ou mais dos outros quatro grafo-elementos referidos foram observados em 131 destes pacientes (80 do sex
View details →Negative / Null Result ReportOpen accessMedicine (General)
Wicensius Parulian Hasudungan, Andhika Rachman, Alvina Widhani et al. · 2025 · Jurnal Penyakit Dalam Indonesia
Introduction. The available data currently is not adequate to show the differences in vitamin D levels across various clinical stages of COVID-19 in Indonesia. Therefore, this study was conducted to determine the profile of vitamin D levels and its relationship with the clinical severity and inflammatory parameters in confirmed COVID-19 patients. Methods. The study was conducted at Cipto Mangunkusumo Hospital and Wisma Atlet COVID-19 Emergency Hospital from January to December 2021. Subjects who were 18 years old and above and had confirmed COVID-19 status through COVID-19 Polymerase Chain Rea
View details →Negative / Null Result ReportOpen accessPharmacy and materia medica
Maryam Hassan Al-Zahrani, Nawal Marzoog Almutairi · 2023 · Journal of Pharmacy and Bioallied Sciences
Background/Objective/Methods: Glutathione-S-transferase Mu1 (GSTM1) and glutathione peroxidase 1 (GPX1) are known antioxidant enzymes that help protect cells from the oxidative damage that occurs from smoking. This study explored the correlation between GSTM1 and GPX1 levels between a group of smokers with the GSTM1 and GPX1 genes in the Saudi population and a control group and investigated the genetic risk factors in the group of smokers. Results: The control and smokers' group (n = 50; aged 22.3 ± 3.1 years; BMI 24.6 ± 5.9 kg/m2) were genotyped using quantitative polymerase chain reaction (q
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