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Browse the failure-mode index

19,878 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Single antiplatelet therapy vs oral anticoagulation monotherapy in patients with atrial fibrillation and coronary artery disease after successful catheter ablation: A target trial emulation.

Li F, Zhao Y, Peng X et al. · 2026 · Heart rhythm

Background The optimal long-term antithrombotic strategy in patients with atrial fibrillation (AF) and coronary artery disease (CAD) after successful catheter ablation (CA) remains uncertain. Objective This study aimed to compare the…

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Negative / Null Result ReportOpen accessMedicine

Evaluating the Effectiveness of Age Simulation Gloves.

Lüleci EH, Kedgley AE · 2026 · Human factors

ObjectiveThis study evaluated the effectiveness of age simulation gloves in replicating age-related declines in hand function.BackgroundCommercially available age simulation gloves are increasingly used. However, their ability to replicate…

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Negative / Null Result ReportOpen accessMedicine

A comparative analysis of the performance of leading large language models on the endodontics section of the dentistry specialization exam in Türkiye.

Başkan B, Başkan HK, Koç N · 2026 · PloS one

Objective This study aimed to evaluate and compare the performance of eight contemporary LLMs on the endodontics section of the DUS, assessing their accuracy in both theoretical knowledge and simulated clinical scenarios from historical…

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Negative / Null Result ReportMedicine

Artificial intelligence-generated patient information on shoulder instability remains suboptimal: DeepSeek outperforms ChatGPT in completeness of content while ChatGPT is more readable.

Öğümsöğütlü E, Bozgeyik B, Huri G · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

Purpose This study aimed to evaluate and compare the performance of the Chat Generative Pre-Trained Transformer (ChatGPT) and DeepSeek artificial intelligence (AI) models for patient information on shoulder instability. Methods Sixteen…

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Negative / Null Result ReportOpen accessMedicine

Vitamin D receptor gene polymorphism and its association with the susceptibility to Helicobacter pylori infection in the Egyptian population with hepatocellular carcinoma.

Ibrahim A, Abdelhady SA, Rageh F et al. · 2026 · BMC gastroenterology

OBJECTIVE: This study aimed to estimate the frequency of H. pylori infection in patients with liver disorders, and identify the relationship between vitamin D receptor gene variants and susceptibility to H. pylori infections and HCC in…

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Negative / Null Result ReportOpen accessMedicine

CBCT in Evaluation of Root Canal Preparation-A Scoping Review.

Vidal A, Teles AM, Cardoso M et al. · 2026 · Dentistry journal

Cone-beam computed tomography (CBCT) is widely utilized in endodontics for evaluating root canal shaping outcomes, offering critical three-dimensional imaging capabilities. This study aims to assess the differences in apical and root canal…

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Negative / Null Result ReportMedicine

Postoperative antibiotic prophylaxis following cardiac implantable electronic device implantation and the risk of device infection.

Mandler I, Krutik T, Biham O et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

BACKGROUND AND AIMS: Cardiac implantable electronic devices (CIEDs) are essential for the management of cardiac arrhythmias. Device infection is one of the most dismal complications of CIED implantation. The aim of this study is to assess…

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Negative / Null Result ReportOpen accessMedicine

Are Skip Laminectomy and Oblique Corpectomy Effective Options to Treat Degenerative Cervical Myelopathy While Preserving Motion? Results of a Scoping Review.

Lomax JL, Mehta A, Vedantam A et al. · 2026 · Global spine journal

Study DesignScoping Literature Review.ObjectiveThe aim of this literature review is to examine the results of both skip laminectomy and oblique corpectomy in the setting of degenerative cervical myelopathy (DCM).MethodsA scoping review of…

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Negative / Null Result ReportOpen accessMedicine

Health-related quality of life scores of ultralow rectal cancer patients after conformal sphincter preservation operation compared to newly derived preoperative EORTC QLQ-C30, CR38 reference values and EORTC QLQ-C30 norm.

Ding HB, Sun G, Yu GY et al. · 2026 · Frontiers in oncology

Background Postoperative quality of life (Post-QoL) is the key to measuring the effectiveness of sphincter-preserving operation such as Conformal sphincter preservation operation (CSPO) for ultralow rectal cancer. This study aimed to…

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Negative / Null Result ReportMedicine

Correlation Between Morphology of Reinke's Edema and Disease Regression After Office-Based Laser Therapy and Steroid Injection.

Hamdan AL, Abou Raji Feghali P, Lababidi G et al. · 2026 · Journal of voice : official journal of the Voice Foundation

Objective To investigate the association between the morphology and the severity of Reinke's edema (RE) and disease regression following office-based blue laser therapy (OBLT) and steroid injection. Study design Retrospective Review…

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Negative / Null Result ReportOpen accessMedicine

Retrograde Intrarenal Renal Surgery versus Supine Mini Percutaneous Nephrolithotripsy in Treatment of Renal Pelvic Stones Less than 2 cm, Randomized Clinical Study.

Abdelgawad AH, Elhawy MA, Hussein AAHF et al. · 2026 · Urology research & practice

Objective Retrograde intrarenal surgery (RIRS) is the first-line treatment for kidney stones between 1 and 2 cm and can serve as an alternative to percutaneous nephrolithotomy for larger stones in high-risk patients, including those with…

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Negative / Null Result Report

Comparison of the ChatGPT and DeepSeek models in responding to multiple choice questions related to rehabilitation of completely edentulous patients with complete dentures

Bhochhibhoya A, Maskey B, Shrestha R et al. · 2025 · Preprint

Abstract Background. Artificial intelligence (AI) chatbots are considered a potential resource for dental education. However, there is still a lack of adequate knowledge regarding the trustworthiness, validity, and utility of the content…

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Negative / Null Result ReportOpen accessMedicine

Two-year outcomes of fenestrated and branched stent grafts in patients ≤65 years: A bicenter retrospective study.

Van Weydevelt E, Alrajhi Z, Vannier C et al. · 2026 · Journal of vascular surgery cases and innovative techniques

Objective Fenestrated and branched endovascular aortic repair (F/BEVAR) is increasingly used to treat complex abdominal aortic aneurysms and thoracoabdominal aortic aneurysms (TAAAs) because of their minimally invasive nature compared with…

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Negative / Null Result ReportOpen accessMedicine

Protein Creatinine ratio versus 24-h test in HIV-positive and HIV-negative women with pre-eclampsia.

Mkhize SF, Moodley J, Khaliq OP et al. · 2026 · South African family practice : official journal of the South African Academy of Family Practice/Primary Care

Background Pre-eclampsia (PE) is a major contributing factor to high rates of maternal and perinatal morbidity and mortality in South Africa. Early diagnosis is currently a challenge. The objective is to assess the diagnostic accuracy of…

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Negative / Null Result ReportMedicine

Low-Dose Aspirin is Not Associated with Increased Risk of Postpartum Hemorrhage.

Ali M, Higginbotham A, Sabri E et al. · 2026 · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC

Objectives Aspirin (ASA) is recommended for preeclampsia prophylaxis, but it is uncertain whether higher doses, such as the 150 mg/day used in the ASPRE trial, increase the risk of postpartum hemorrhage (PPH). In Canada, the available…

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Negative / Null Result ReportOpen accessMedicine

Effects of dried Azolla pinnata supplementation on growth, biochemistry, and reproduction in female rabbits.

Abd-Elfadiel Hagag OY, Ahmed-Helmy El-Rayes M, El-Hawy AS et al. · 2026 · Tropical animal health and production

This study evaluated the impact of incorporating varying levels of dried Azolla pinnata as a partial or full substitute for soybean meal protein on growth performance, productivity, and selected biochemical, immunological, hormonal, and…

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Negative / Null Result ReportOpen accessMedicine

The interplay of night eating syndrome with resting metabolic rate, anthropometric measures, and sleep quality in normal-weight female university students: a case-control study.

Aslan S, Sozlu S, Bozkurt O et al. · 2026 · Journal of eating disorders

Aims Night eating syndrome (NES) is characterized by food consumption during bedtime or late night. This study aimed to evaluate the relationship between NES and resting metabolic rate (RMR), anthropometric measurements, and sleep quality.…

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Negative / Null Result ReportOpen accessMedicine

Corticosteroids with or without antiviral therapy in elderly patients hospitalized with COVID-19 during the Omicron era: A multicenter real-world study.

Xu S, Huang Z, Zou X et al. · 2026 · Journal of virus eradication

Background Elderly patients remain at high risk for adverse outcomes from COVID-19 despite the generally reduced pathogenicity of the Omicron variant. Corticosteroids are commonly used in hospitalized patients with COVID-19, particularly…

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