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19,878 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Multiple sclerosis and related disorders multiple sclerosis across Isfahan Province, Iran: Urban-rural disparities and no association with air quality measures.

Etemadifar M, Bagheri S, Dehghani A et al. · 2026 · Multiple sclerosis and related disorders

Background Multiple sclerosis (MS) prevalence varies worldwide and appears to be rising in Iran. Environmental factors like air pollution have been hypothesized to contribute to MS risk. This study aimed to map MS prevalence across Isfahan…

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Negative / Null Result ReportMedicine

Association of Triglyceride-glucose Index and Obesity Metrics with Cardiovascular Disease Among U.S. Adults with Hyperlipidemia: Findings from the NHANES 2007-2016.

Lan P, Lan T · 2026 · Metabolic syndrome and related disorders

Background Hyperlipidemia constitutes a systemic metabolic disorder. The correlation of cardiovascular disease [CVD] with the triglyceride-glucose index [TyG] in individuals with hyperlipidemia remains unclear. The current study examined…

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Negative / Null Result ReportMedicine

Does Remodeling of Distal Femoral Extension Osteotomy Cause Recurrence of Knee Flexion Deformity in Children With Cerebral Palsy?

Gahukamble A, Arikrishnan AM, Thuppale VE et al. · 2026 · Journal of pediatric orthopedics

Background Distal femoral extension osteotomy (DFEO) is an established surgical option for correcting knee flexion deformity (KFD) in children with cerebral palsy. However, the extension deformity created at the distal femur may remodel…

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Negative / Null Result ReportMedicine

Phthalate esters and microplastics in sediments of Haomeiliao Wetland, Southwestern Taiwan: Occurrence, spatial distribution, and management implications.

Bandola AM, Wang MH, Guo BF et al. · 2026 · Marine pollution bulletin

Phthalate esters (PAEs) and microplastics (MPs) are emerging contaminants in aquatic environments. However, their co-occurrence in wetland sediments remains poorly understood. This study aimed to quantify PAE concentrations and MP…

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Negative / Null Result ReportMedicine

Impact of SLCO1B1 Gene Polymorphisms on Vadadustat Pharmacokinetics.

Yokoyama S, Shimada M, Nakagawa J et al. · 2026 · European journal of drug metabolism and pharmacokinetics

Background and objective Vadadustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, is transported into hepatocytes via OATP1B1, which is encoded by the SLCO1B1 gene. Although interindividual variability in vadadustat…

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Negative / Null Result ReportOpen accessMedicine

The role of Spexin and Phoenixin-20 in girls during puberty.

Koca SB, Kırkgöz T, Kara L et al. · 2026 · BMC endocrine disorders

BACKGROUND: Spexin has an inhibitory effect on the hypothalamus (GnRH expression), pituitary (LH and FSH expression) and ovary (estradiol expression). However, Phoenixin potentiate GnRH-stimulated GnRH receptor expression. Our aim is to…

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Negative / Null Result ReportMedicine

A structured teaching module for postoperative follow-up in urology residency training: development and evaluation of an IMDB-based educational tool.

Sun X, Zhou Q, Qian W et al. · 2026 · BMC medical education

Background Teaching postoperative follow-up for renal cell carcinoma (RCC) is challenging during brief urology rotations. We evaluated a structured module based on a simplified risk model (IMDB: venous invasion, tumor size ≥ 7 cm, systemic…

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Negative / Null Result ReportOpen accessMedicine

Are HDAC and Glutamine Synthetase Expression Levels Associated with Ga68-DOTATATE PET/CT Data and Prognosis in Gastroenteropancreatic Neuroendocrine Tumours?

Ulas O, Yuceer RO, Hasbek Z et al. · 2025 · Medicina (Kaunas, Lithuania)

Background and Objectives : Neuroendocrine neoplasms are heterogeneous tumours arising from endocrine gland cells and the neuroendocrine system. Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) constitute two-thirds of this tumour…

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Negative / Null Result ReportMedicine

Right ventricular systolic function in dogs with pulmonary hypertension can be assessed using tissue motion annular displacement.

Silva VBC, Lucina SB, Wolf M et al. · 2026 · American journal of veterinary research

Objective To assess right ventricular (RV) systolic function using conventional echocardiography and advanced techniques, including strain and tissue motion annular displacement (TMAD), in dogs with and without pulmonary hypertension (PH).…

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Negative / Null Result ReportMedicine

From Mother-Infant Dyad to Mother-Father-Infant Triad: A Cross-Sectional Study on Fathers' Breastfeeding Attitudes and Participation.

Çerçer Z, Biçer Şahin F, Kanarya T · 2026 · Journal of human lactation : official journal of International Lactation Consultant Association

Background and aim It is important to include fathers in the evaluation of the breastfeeding process. This study aimed to assess fathers' breastfeeding attitudes and participation. Methods The cross-sectional study data were collected…

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Negative / Null Result ReportMedicine

Early postoperative corneal thickness and 12-month endothelial cell outcomes after descemet membrane endothelial keratoplasty: A multicentre analysis.

Igarashi A, Rekate A, Fujiwara K et al. · 2026 · Acta ophthalmologica

Purpose To evaluate whether early postoperative corneal thickness is associated with 12-month endothelial cell and visual outcomes after Descemet membrane endothelial keratoplasty (DMEK). Methods This retrospective multicentre study…

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Negative / Null Result ReportOpen accessMedicine

Echocardiographic Findings in Small-Breed Dogs With Myxomatous Mitral Valve Disease and the Severity of Mitral Regurgitation, Heart Size and Clinical Signs Myxomatous Mitral Valve Disease in Dogs.

Elyasi B · 2026 · Veterinary medicine and science

Background The main goal of this study was to identify various brightness, motion and Doppler echocardiographic variables in small-breed dogs with myxomatous mitral valve disease. Animals Sixty client-owned small-breed dogs with mitral…

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Negative / Null Result ReportMedicine

EXPRESS: Longitudinal comparison of serum pancreatic lipase activity and pancreatic lipase immunoreactivity with clinical signs in cats with suspicion of pancreatitis.

Kook PH · 2026 · Journal of feline medicine and surgery

ObjectivesIt remains unclear whether pancreatic lipase immunoreactivity (PLI) and lipase activity similarly reflect clinical status and disease severity in cats with suspected pancreatitis. This retrospective cohort study aimed to directly…

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