19,875 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Mirzania, Anari, Emami et al. · 2026 · International journal of breast cancer
Locally advanced breast cancer (LABC) remains a major therapeutic challenge, with neoadjuvant chemotherapy (NAC) serving as a cornerstone of management. However, direct evidence comparing the efficacy of sequential (AC-T) and concurrent…
View details →Wang, Wang, Luo et al. · 2026 · Frontiers in veterinary science
This study aimed to assess the effectiveness of intelligent mosquito surveillance devices implemented in Zhejiang Province and to compare these metrics with those obtained from traditional surveillance methods. Intelligent surveillance…
View details →Zolfaghari, Nouri Habashi, Aghazadeh · 2026 · Veterinary research forum : an international quarterly journal
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder. Exercise is one of the interventions that leads to PCOS improvement. This study aimed to investigate the potential of different durations of high-intensity interval training…
View details →Hafizi, Azizi, Mahmoudinia et al. · 2026 · Health science reports
There is evidence of the beneficial effects of acupuncture in the treatment of polycystic ovary syndrome (PCOS). This study aimed to compare acupuncture with clomiphene in ovulation induction among infertile women with PCOS. This…
View details →Liu, Zheng, Li et al. · 2026 · Cardiology research
The study aimed to compare the efficacy and safety of simplified single-freezing protocol with achieving -40 °C within 60 s of freezing as the observation index and the conventional time-to-isolation (TTI)-guided double-freezing…
View details →Ferrandon-Berne, Pelletier Visa, Dobija et al. · 2026 · Archives of rehabilitation research and clinical translation
To investigate the relationship between the occurrence of falls and the time taken to perform the Timed Up and Go (TUG) test in a population of patients with Charcot-Marie-Tooth disease type 1A (CMT1A). We conducted a longitudinal,…
View details →Costa, de Oliveira, do Couto et al. · 2026 · Brazilian journal of veterinary medicine
This study determined whether administration of buserelin acetate (BA), a gonadotropin-releasing hormone agonist, during timed artificial insemination (TAI) improves pregnancy per AI (P/AI) of dairy cows inseminated with sexed semen. A…
View details →Rawal, Asawa, Das et al. · 2026 · Cureus
Background Gingivitis, a reversible inflammatory condition of the gingiva, is primarily caused by plaque accumulation. Chlorhexidine is the gold standard for plaque control, but it is associated with side effects on prolonged use.…
View details →Zheng, Chen, Sui et al. · 2026 · Drug design, development and therapy
Laparoscopic sleeve gastrectomy (LSG) is associated with substantial postoperative pain and a high rate of postoperative nausea and vomiting. Tegileridine fumarate, a biased µ-opioid receptor agonist, may offer effective analgesia…
View details →Liu, Yu, Gao et al. · 2026 · Drug design, development and therapy
To compare the analgesic efficacy and safety of deep, superficial and combined deep-superficial erector spinae plane block (ESPB) combined with subanesthetic-dose esketamine in patients undergoing percutaneous kyphoplasty (PKP). A total of…
View details →Mokkongphai, Pattharanitima, Jeerangsapasuk et al. · 2026 · Kidney diseases (Basel, Switzerland)
Intradialytic hypotension (IDH) is a major complication during hemodialysis (HD), leading to arrhythmias and increased mortality. Inaccurate dry weight (DW) adjustment contributes to IDH. Bioelectrical impedance analysis (BIA) is commonly…
View details →Jia, Xu, Xu et al. · 2026 · Frontiers in surgery
The clinical results of a total knee arthroplasty (TKA) without patellar resurfacing for knee osteoarthritis have been reported; however, not regarding comparison patellofemoral joint (PFJ) clinical outcomes using different prosthesis…
View details →Plumarom, Singsuwit, Marsh et al. · 2026 · Bone & joint open
The aim of the study was to assess progression of fracture healing after locking plate osteosynthesis with hybrid fixation compared with non-hybrid fixation in the distal femur, using the modified Radiological Union Scale for Tibia…
View details →Lansley, McSweeney, Rutere et al. · 2026 · Medical teacher
Immersive extended reality (iXR) technologies are increasingly adopted within health professions education. However, existing evidence has largely focused on technical skill acquisition or learner satisfaction, with limited examination of…
View details →Moon, Cho, Kim et al. · 2026 · Ewha medical journal
Rectus sheath block (RSB) is a simple abdominal wall block that can be readily applied. This study evaluated the postoperative analgesic efficacy of ultrasound-guided bilateral RSB in robotic single-site gynecologic surgery. Sixty patients…
View details →Coates, Bak, Rajagopalan et al. · 2026 · World journal of surgery
As obesity becomes more common, understanding its risks in routine operations is increasingly important. This study assessed the impact of obesity on intraoperative complications during elective laparoscopic cholecystectomy. Retrospective…
View details →Barbalho, Brugger, Gratieri et al. · 2026 · European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Transfersomes are deformable lipid vesicles extensively evaluated for transdermal drug delivery. However, the ocular penetration mechanism of transfersomes is poorly understood as the effect of tear flow, which by altering osmotic…
View details →Kılıç, Turkgenc, Baltrak et al. · 2026 · Pediatric surgery international
Failures of testicular descent may result in the condition known as an undescended testis (UDT). While mechanical and hormonal causes have been researched quite extensively, not much is known about the underlying genetics. Developmental…
View details →Yang, Ye, Cao et al. · 2026 · BMC oral health
This study primarily aimed to identify prognostic factors for patients with recurrent/metastatic tongue squamous cell carcinoma (R/M TSCC) undergoing re-resection and to preliminarily explore the value of baseline metabolic parameters in…
View details →Bayram, Kirac, Yozgatli et al. · 2026 · BMC musculoskeletal disorders
Both partial rotator cuff repair (PRCR) and superior capsular reconstruction (SCR) are frequently performed arthroscopically to treat non-pseudoparalytic massive irreparable rotator cuff tears (MIRCT). The purpose of this study was to…
View details →Serrano, Gueugneau, Ravier · 2026 · Scientific reports
This study examined modulations of the cardiac autonomic nervous system, neuromuscular performance and psychological states during the menstrual cycle (MC) in naturally menstruating women. Fifteen healthy young females were tested during…
View details →Kitahara, Ohshima, Nakajima et al. · 2026 · Scientific reports
Full-endoscopic spine surgery performed under local anesthesia offers clinical advantages, particularly for elderly patients. However, its reliance on fluoroscopy raises concerns about occupational radiation exposure. Although several…
View details →da Silva, Alves, Jalkh et al. · 2026 · Dental materials : official publication of the Academy of Dental Materials
To evaluate microbial inhibition at the implant-abutment interface of 5Y-PSZ zirconia abutments coated with boron-doped soda-lime glass, with or without silver, and to evaluate the fatigue lifetime of boron-doped soda-lime glass-coated…
View details →Shang, Ma, Chen et al. · 2026 · Waste management (New York, N.Y.)
Ammonia (NH 3 ) is a key odorous gas emitted from livestock and poultry farming, and biofiltration has been widely used for NH 3 removal. Temperature plays a critical role in regulating microbial activity and greenhouse gas emissions in…
View details →Zhou, He, Cheng et al. · 2026 · CNS neuroscience & therapeutics
To compare the real-world effectiveness, surgical and economic outcomes of preoperative rapid antibody clearance therapy (RACT: lymphoplasmapheresis (LPE), efgartigimod (EFG)) versus oral immunosuppressants (Oral IS) in generalized…
View details →Fukuda, Blackwood, Kim et al. · 2026 · Journal of neurointerventional surgery
Combined delivery catheter systems (CDCS) with ledge-reducing obturators are designed to streamline aspiration-first mechanical thrombectomy, yet comparative multicenter data across platforms remain limited. To determine whether an…
View details →Giorgini, Xavier, da Silva et al. · 2026 · Topics in companion animal medicine
LINE-1 (long interspersed nuclear element-1) is a family of related class I transposable elements in the DNA that is dispersed throughout the entire genome and the study of its methylation pattern is used in the understanding of several…
View details →Tran, Padda, Sharma et al. · 2026 · Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
A major challenge in teaching slit-lamp biomicroscopy is providing adequate depth perception and anatomical detail; the Deep Reality Viewer (DRV) addresses this by enabling stereopsis. This study evaluated the utility of DRV for slit-lamp…
View details →Björkman, Malusek, Persson et al. · 2026 · European radiology experimental
The aim was to compare the image quality of photon-counting detector CT (PCD-CT) and energy-integrating detector CT (EID-CT) in patients with tibial plateau fractures treated with metallic osteosynthesis material, and to identify optimal…
View details →Hironori Sadamatsu, Yuki Kurihara, Koichiro Takahashi et al. · 2019 · Case Reports in Oncology
Paraneoplastic limbic encephalitis (PLE) is a rare neurologic disorder that can complicate various malignancies, including lung cancer. PLE is most frequently found the initial presentation of lung cancer. In this study, we reported the case of a 74-year-old Japanese woman who developed PLE after partial remission of small cell lung cancer (SCLC) by first-line systemic chemotherapy. Brain magnetic resonance imaging showed no metastatic tumor or cerebrovascular disease. Anti-glutamic acid decarboxylase (GAD) and anti-amphiphysin antibodies were detected in her serum. She was diagnosed as having
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