20,233 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ward J, Agbude R, Smees R et al. · 2025 · Preprint
This study examined the concentrations of excitatory and inhibitory neurotransmitters (glutamate and GABA respectively) in two regions of interest (auditory and insular cortices) and a control region (visual cortex) to test the hypothesis…
View details →Bar Or M, Schonberg T · 2025 · Preprint
Understanding habit formation in humans remains a fundamental challenge, partly due to the constraints of laboratory-based studies. Thus, this study investigated whether prolonged, real-world engagement with a novel smartphone-based task…
View details →Guest H, Plack CJ, Munro KJ et al. · 2026 · International journal of audiology
Objective Adult auditory brainstem response (ABR) amplitudes are employed by both researchers and clinicians, but exhibit substantial between-subject variability, reducing their sensitivity as measures of underlying auditory health. One…
View details →Bar Or M, Schonberg T · 2025 · Preprint
Understanding habit formation in humans remains a fundamental challenge, partly due to the constraints of laboratory-based studies. Thus, this study investigated whether prolonged, real-world engagement with a novel smartphone-based task…
View details →Nielsen SP, Mathiesen L, Møller P · 2025 · Basic & clinical pharmacology & toxicology
This review examines the association between early life exposure to phthalates in human males and Leydig cell endocrine function. A systematic search was performed in PubMed and EMBASE, identifying 17 studies for analysis. Association…
View details →Zhu J, Yi Y, Ma L et al. · 2026 · Italian journal of pediatrics
BACKGROUND: Observational epidemiology studies suggested a relationship between single-carbon metabolism and vitamin levels with autism spectrum disorder (ASD) risk. We aimed to explore the causal relationship between them at the genetic…
View details →Rosales MR, Pulido JC, Sideris J et al. · 2026 · PloS one
Introduction Motor impairments have been reported in infants at elevated likelihood of autism and those later diagnosed with autism. However, empirical studies comparing higher to lower likelihood infants are lacking, limiting our…
View details →Bouwman V, Pittig A, Engelhard I et al. · 2025 · Preprint
Although exposure-based Cognitive Behavioral Therapy is generally effective for anxiety disorders, many people do not benefit. A better understanding of treatment predictors is required. This study investigated whether the dynamics of…
View details →Gusmão B, Zürn MK, Topolinski S · 2026 · Cognition & emotion
Individuals attribute a higher truth value to repeated compared to novel information, the well-known truth effect. Also, information that contradicts what we have heard earlier is considered falser than both repeated and completely new…
View details →Nieves-Méndez C · 2025 · Frontiers in human neuroscience
This perspective article explores the transformative potential of brain-Computer Interfaces (BCI) in undergraduate systems engineering programs, a domain characterized by high attrition and a widening gap between rapid technological…
View details →Alotaibi AM, Alosaimi MH, Orfali RS et al. · 2025 · Brain research bulletin
Hallucinations are often associated with alterations in brain activation, particularly in language-related and sensory processing areas. Existing models suggest different frameworks for understanding the relationship between brain…
View details →Newton JD, Ellis T, Ruther M et al. · 2026 · Environmental research
Living near green areas with high vegetation may contribute to an active lifestyle, stress reduction, and enhance social cohesion, and consequently may be associated with improved cancer survival. Epidemiologic studies focused on greenness…
View details →Okunoye G, George Samuel C, Abdullahi H et al. · 2026 · Cureus
Gestational diabetes mellitus (GDM) is a common pregnancy complication with significant maternal and neonatal risks, and its prevalence is particularly high in Qatar. Myo-inositol has been proposed as an insulin-sensitizing supplement that…
View details →Jun S, Bido-Medina R, Oviedo J et al. · 2025 · Preprint
Systemic viral infections with neurotropic potential pose significant global health challenges. The Zika virus (ZIKV) is known for its pronounced neurotropism, with recent infectious clusters raising renewed public health concerns. While…
View details →Verhelst H, Gerrits R, Karlsson EM · 2025 · Neurobiology of language (Cambridge, Mass.)
Developmental dyslexia is a common learning disability marked by reading and spelling difficulties. While previous imaging studies aiming to elucidate the neurobiological mechanisms of this disorder have reported white matter alterations,…
View details →Andersson PF, Testori M, Lo Iacono S · 2026 · PloS one
The willingness to engage in costly punishment of free riders (prosocial punishment) is crucial to foster group cooperation and understand public goods provision. While prosocial punishment is common across societies, its motivations…
View details →Aguado J, Gutierrez L, Forns J et al. · 2025 · American journal of epidemiology
Studying the effect of duration of treatment on prognostic outcomes using real-world data is challenging because only people who survive for a long time can receive a treatment for a long time. Specifying a target trial helps overcome such…
View details →D'Agostini M, Vanden Bossche L, Burger AM et al. · 2025 · Psychophysiology
Transcutaneous auricular vagus nerve stimulation (taVNS) has been tested as a strategy to facilitate fear extinction learning based on the hypothesis that taVNS increases central noradrenergic activity. Four studies out of six found taVNS…
View details →· 2025 · Nature
Neutrinos are the most abundant fundamental matter particles in the Universe and play a crucial part in particle physics and cosmology. Neutrino oscillation, discovered about 25 years ago, shows that the three known species mix with each…
View details →Xiang Y, Xu L, Sun Y et al. · 2025 · Medicine
Mobile phone use has become ubiquitous in modern life, raising public concern over its potential effects on male reproductive health. While several observational studies have reported associations between prolonged phone use and decreased…
View details →He J, Sabroso-Lasa S, Coscia C et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Observational studies consistently report reduced pancreatic ductal adenocarcinoma (PDAC) risk among individuals with atopic conditions (asthma and rhinitis); however, the underlying biological mechanism remains unclear. This…
View details →Schleimer JP, Rencken CA, Wagenaar BH et al. · 2026 · JAMA network open
Importance Background checks aim to prevent illegal firearm transfers. Existing research has shown little evidence for the effect of point-of-sale comprehensive background check (CBC) policies on firearm-related violence at the state…
View details →Nielsen SP, Mathiesen L, Moller P · 2024 · Preprint
not-yet-known not-yet-known not-yet-known unknown Abstract This review examines the association between early life exposure to phthalates in human males and Leydig cell endocrine function. A systematic search was performed in PubMed and…
View details →Walda SAE, van Weerdenburg M, Bosman AMT · 2024 · Research in developmental disabilities
Background Poor decoding and spelling (literacy) skills have been associated with weak working memory. Aims The aim of this study was to elucidate the contribution of working memory to literacy progress in students with dyslexia. It has…
View details →Bertoldi AD, Flores TR, Silveira MPT et al. · 2026 · Ciencia & saude coletiva
This study aimed to investigate the association between the use of antimicrobials during pregnancy and excess weight in children at ages three, 12, 24 and 48 months. Data of participants from the 2015 Pelotas (Brazil) Birth Cohort study…
View details →Hiredesai AN, Martinez CJ, Hinckley NB et al. · 2026 · Cureus
Purpose Shear wave elastography (SWE) is a non-invasive technique for assessing median nerve (MN) stiffness in carpal tunnel syndrome (CTS). This study evaluated whether SWE measurements of the MN improve after corticosteroid injection…
View details →Pater WJ, Buller LT, Ziemba-Davis M et al. · 2026 · Arthroplasty today
Background Tourniquet use in revision total knee arthroplasty (rTKA) enhances visualization and improves cement penetration. However, concerns exist about muscle injury, pain, wound complications, and venous thromboembolism (VTE). This…
View details →Gao S, Gross AL, Aksman LM et al. · 2026 · Journal of Alzheimer's disease : JAD
BackgroundPlasma neurodegenerative biomarkers are a potential low-cost tool for studying Alzheimer's disease and dementia in population-based research, especially in low- and middle-income countries. However, their associations with…
View details →Atkinson A, Marschall J, Burnham JP · 2025 · Antimicrobial resistance and infection control
Background Air changes per hour (ACH) in operating rooms (ORs) are energy intensive, and optimal air change settings are not known. Objectives We sought to explore whether there is a relationship between surgical site infections (SSIs)…
View details →Perales-Puchalt J, Yang FM, Townley R · 2025 · Alzheimer disease and associated disorders
We tested the efficacy of docosahexaenoic acid (DHA) supplementation on aggressive behavior among people with dementia. We used secondary data from a randomized, double-blind, placebo-controlled trial. Analyses included 402 individuals…
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