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19,859 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Identification and multi-layered validation of seven diagnostic biomarkers for dilated cardiomyopathy via integrative machine learning, single-cell transcriptomics, and Mendelian randomization.

Li J, Song Z, Wang G et al. · 2026 · Frontiers in cell and developmental biology

Background Dilated cardiomyopathy (DCM) is the most common non-ischemic cardiomyopathy and a major cause of heart failure, but disease-specific molecular biomarkers remain limited. This study aimed to identify and prioritize tissue-level,…

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Negative / Null Result ReportOpen accessMedicine

Non-Essential Element-Based Nanoparticles in Rice: Unraveling the Impacts of Yttrium Oxide and Zirconium Oxide Nanoparticles on Root Accumulation and Antioxidant Responses.

Xie B, Rui Y · 2026 · Plants (Basel, Switzerland)

Nanotechnology has attracted increasing attention in agricultural and environmental research, but the biological effects and potential risks of nanoparticles based on non-essential elements remain insufficiently understood. This study…

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Negative / Null Result ReportMedicine

Current comorbid psychiatric symptoms in the statistical indirect association between childhood attention-deficit/hyperactivity disorder symptoms and functional impairment among university students.

Koyuncu Z, Evcil FY, Kilimci ÖS et al. · 2026 · BMC psychiatry

Objective This study investigated whether current comorbid psychiatric symptoms were involved in statistical indirect associations between childhood attention-deficit/hyperactivity disorder (ADHD) symptoms (CAS) and functional impairment…

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Negative / Null Result Report

High Concordance in Molecular Profiles Between Primary Tumors and Matched Lymph Node Metastases in Differentiated Thyroid Carcinoma: Implications for Clinical Sample Selection

Pan Y, Sun Y, Shi C et al. · 2026 · Preprint

Abstract Genetic testing guides personalized management of differentiated thyroid carcinoma (DTC). However, tumor heterogeneity, including spatial and temporal heterogeneity, has created an unresolved clinical problem. It remains unclear…

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Negative / Null Result ReportMedicine

Influence of inhalation exposure to biogenic volatile organic compounds from Syringa oblata flowers on behavior, spatial working memory, and hematological parameters in mice.

Tuo Y, Yang S, Dai X et al. · 2026 · Journal of ethnopharmacology

Ethnopharmacological relevance Syringa oblata Lindl. emits a variety of biogenic volatile organic compounds (BVOCs) during full bloom, which forms the key chemical basis for its characteristic floral scent. Species of the genus Syringa…

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Negative / Null Result ReportMedicine

Exploring Emotional Abuse, Physical Abuse and Mobile Phone Dependence in Left- and Non-Left-Behind Adolescents: Roles of Self-Esteem, Social Anxiety, and Loneliness.

Zhen B, Yang X, Yao B · 2026 · Scandinavian journal of psychology

Child abuse has been significantly associated with children's mobile phone dependence (MPD), particularly in left-behind children (LBC). However, whether distinct forms of child abuse (physical and emotional) are associated with MPD in LBC…

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Negative / Null Result ReportMedicine

Plasma protein biomarkers for early risk prediction of colorectal cancer.

Chen W, Ge X, Hu C et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Prospective studies are necessary to determine the association between circulating proteins and colorectal cancer (CRC) risk, offering non-invasive biomarkers for early CRC risk prediction and interventions. The Olink Explore-3072 platform…

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Negative / Null Result ReportMedicine

Preliminary investigation of T-wave peak-end interval and its ratio to QT interval in dogs with an echocardiographic phenotype of dilated cardiomyopathy and its possible correlation with left ventricular diameter and volume.

Kurogochi K, Stern JA, DeFrancesco TC et al. · 2026 · Journal of the American Veterinary Medical Association

Objective The T-wave peak-end (TpTe) interval and its ratio to the QT interval (TpTe:QT) are ECG markers of myocardial repolarization dispersion. We hypothesized that these markers are associated with echocardiographic indices reflecting…

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Negative / Null Result ReportOpen accessMedicine

Anticoccidial efficacy of a cinnamon-Rumex nervosus phytobiotic mixture on growth performance, carcass traits, cecal morphology, and cecal health in Eimeria tenella-challenged broilers.

Qaid MM, Al-Garadi MA, Al-Abdullatif AA et al. · 2026 · Poultry science

Coccidiosis remains a major constraint in poultry production; therefore, this study evaluated the anticoccidial efficacy of a phytogenic blend of cinnamon bark and Rumex nervosus leaf in Eimeria tenella-challenged broilers. Birds were…

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Negative / Null Result ReportOpen accessMedicine

Discrepant Intracranial and Extracranial Responses to Tarlatamab in Relapsed Small-Cell Lung Cancer With Untreated Brain Metastases: A Case Report.

Hayashi E, Kano H, Nakamura K et al. · 2026 · Respirology case reports

Small-cell lung cancer (SCLC) has a poor prognosis, and the efficacy of tarlatamab for untreated brain metastases remains unclear. We report a case demonstrating a discrepant response between extracranial and intracranial lesions after…

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