20,227 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Duckett W, Simons J · 2025 · Preprint
Vivid mental imagery is often assumed to relate to memory accuracy, but recent empirical findings from studies of aphantasia have found conflicting results regarding this association. The present study investigates the relationship between…
View details →Mehari KR, Schuler KR, Haiflich A et al. · 2025 · Violence and victims
This study examined the implementation of a state law in the southern United States that required hospitals to report gunshot wounds (GSWs) to law enforcement by exploring changes in the proportion of reported GSW cases in a level 1 trauma…
View details →Gago T, Sargisson RJ, Milfont TL · 2025 · Preprint
Despite being an important mental health consequence of climate change, climate anxiety assessment has been fragmented. Reviews of measures of climate anxiety raise concerns about content and convergent validity. We aimed to select the…
View details →Hernández L, Williamson TM, Campbell T et al. · 2025 · The Canadian journal of cardiology
Background Cardiac rehabilitation (CR) participation improves depressive and anxious symptoms post-coronary catheterization, yet it is unclear to what extent improvements are clinically significant. This study characterized the proportion…
View details →Bagchi A, Sengupta S, Ghosh P et al. · 2026 · Preprint
Abstract Background Rheumatoid arthritis (RA) is associated with inflammation, oxidative stress along with infiltration of immune cells (~ 90% neutrophils) into inflamed joints. Neutrophils have demonstrated the ability to…
View details →Ivanov YV, Kartashov AV, Ivanova AI et al. · 2026 · Functional plant biology : FPB
Global climate change is accompanied by an increase in the frequency and severity of droughts, which negatively impact plant growth. One of the protective mechanisms that allows plants to withstand the negative drought effects is the…
View details →Kalluri VS, Kalluri R · 2026 · Preprint
Tumstatin and Endostatin are endogenous extracellular matrix-derived inhibitors of angiogenesis generated from the non-collagenous domains of type IV and type XVIII collagens, respectively. Although both molecules suppress angiogenesis and…
View details →Mbaluto CM, Martinez-Goni XS, Tripathi A et al. · 2026 · Preprint
Cereal grafting using embryonic tissues has recently become technically feasible; however, the physiological consequences of cereal grafting remain uncharacterized. We systematically evaluate photosynthetic performance and stomatal…
View details →Segura-Chama P, Hernández VS, Zhang L · 2026 · Preprint
Adrenal chromaffin cells are key effectors of the sympathoadrenal response and play a central role in physiological adaptation to stress. While acetylcholine and pituitary ad-enylate cyclase-activating polypeptide (PACAP) are recognized…
View details →Chan A, Freschi L, de-Pinna GFAM · 2026 · Preprint
Abstract Leaf sheaths in monocotyledons may be open or closed, yet the developmental regulation of sheath margins remains unclear in Commelinaceae, a family with closed sheaths. This study investigated the morphogenesis of leaf sheaths in…
View details →Lanham BS, Morris RL · 2026 · Marine environmental research
The strength of biotic stressors (i.e., predation) can determine the success of shellfish reef restoration projects. In recruitment limited systems where seeding is a common restoration strategy, ensuring the survival of seeded individuals…
View details →Turner KM, Svegborn A, Robbins TW · 2026 · Psychopharmacology
Rationale Recent research on habits and skills has produced a wave of new theories regarding the shift in control from medial to lateral regions of the dorsal striatum, and how these regions are implicated in the selected and executed of…
View details →Aumtong S, Soongsoongnoen P, Wanwinit D · 2026 · Scientific reports
Biochar reshapes soil composition for years, yet most evidence comes from short-term, single-element laboratory incubations, leaving multi-element dynamics in tropical soils poorly resolved. We tracked 11 elements in longan-wood biochar…
View details →Heled E, Himai Y, Papelbaum M et al. · 2026 · Journal of psychiatric research
Impaired cognitive flexibility (CF) and elevated perfectionism are well-documented in anorexia nervosa (AN), yet their contribution to symptom severity remains unclear. The current study aimed to examine whether CF predicts symptom…
View details →Pirbornatan A, Chalmeh A, Pourjafar M et al. · 2026 · Veterinary journal (London, England : 1997)
Periparturient immunometabolic adaptations yield small, node-dependent shifts in endotoxin proxies and insulin-sensitivity indices. Direct-fed microbials (DFM) are mechanistically plausible but often produce modest metabolic readouts. Test…
View details →Baranovskaya I, Bilous I, Alexander S et al. · 2026 · Preprint
Mineralocorticoid receptor (MR) blockade exerts sex-specific effects in hypertension and cardiovascular disease; however, its role in blood pressure regulation in spontaneously hypertensive rats (SHR) remains unclear. We assessed the…
View details →Hura A, Green T, Kennedy C · 2026 · Archives of environmental contamination and toxicology
With increasing petroleum transport through coastal waters of the northeastern Pacific, understanding the ecological hazards of these mixtures is essential, yet the sublethal impacts on benthic filter feeders remain poorly characterized.…
View details →Herczeg D, Horváth G, Mikó Z et al. · 2026 · Preprint
The accumulation of microplastics (MP; plastic particles 1 μm – 1 mm in diameter) in the environment is an increasing global concern. Although the physiological effects of MP on organisms, including humans, are increasingly documented,…
View details →Hamilton WL, Moore J, Patel P et al. · 2026 · Preprint
Introduction: Invasive fungal infections (IFI) are an important cause of morbidity and mortality in haemato-oncology (haem-onc) patients with neutropenia, requiring rapid and accurate diagnosis. Gap Statement With widespread use of…
View details →De Gregorio DA, Castro DC · 2026 · Preprint
The mu opioid receptor system has long been recognized for its role in regulating ingestive behaviors and food palatability. However, beyond their robust expression in the brain, opioid receptors are also found throughout the body,…
View details →Wojciechowska M, Rodzeń W · 2026 · Preprint
Background: /Objectives: The present study aimed to examine the relationship between Dark Triad personality traits (narcissism, psychopathy, and machiavellianism) and conspiratorial thinking. Additionally, it sought to investigate whether…
View details →Jorgensen E, Modahl L, Noll A et al. · 2026 · The Journal of the Acoustical Society of America
This study investigated how hearing loss and hearing aid use affect environmental sound ratings in laboratory and real-world contexts using the soundscape framework. Forty-four participants (17 normal hearing, 14 with unaided hearing loss,…
View details →Parrish BP, McCool BA · 2026 · Neuropharmacology
Acute ethanol modulates an incredibly diverse number of neurotransmitter receptors and intracellular pathways. Presynaptic modulation by acute ethanol has been identified at some GABAergic synapses; but descriptions of acute ethanol…
View details →Straszewski A, Troyer S, Boyer MI et al. · 2026 · The Journal of hand surgery
Purpose Routine practices without a clear impact on patient care merit continuous reassessment. This retrospective study evaluated the value of routine histopathologic and culture analysis in patients who underwent flexor or extensor…
View details →Fang SH, Chiang MR, Li CY et al. · 2026 · Journal of muscle research and cell motility
Physical activity induces rapid myokine and metabolic responses in skeletal muscle, yet the immediate cellular adaptations to short-duration contractile activity remain incompletely defined. C2C12 myotubes were exposed to electrical pulse…
View details →Wong R, Robertson R, Meylakh N et al. · 2026 · Neurophysiologie clinique = Clinical neurophysiology
Objectives Electroencephalographic (EEG) studies suggest chronic migraine (CM) is associated with increased global power, especially in somatosensory cortex. Furthermore, recent studies suggest chronic pain is associated with a reduced…
View details →Lopes FM, Bantounas I, Sarov A et al. · 2026 · Nephron
Introduction Human fetal kidneys contain macrophages, innate immune cells postulated to enhance their development. Macrophages have also been implicated in the pathobiology of human kidney malformations and Wilms tumour. Human pluripotent…
View details →Prins PJ, Buga A, Storoschuk K et al. · 2026 · Journal of the American Nutrition Association
Background Exogenous ketone supplementation acutely elevates circulating beta-hydroxybutyrate ( R -BHB), but the impact of chronic repeated dosing on exercise performance, cognition, mood, and cardiometabolic health remains unclear.…
View details →Lee HW, Harris AN, Wall SM et al. · 2026 · American journal of physiology. Renal physiology
Hypokalemia activates intercalated cell acid secretion, but because hypokalemia is typically associated with metabolic alkalosis, this activation cannot be ascribed to extracellular pH. Metabolic acidosis induces responses similar to those…
View details →King JL, Effinger DP, Basquez-Pfeifer C et al. · 2026 · Translational psychiatry
The head-twitch response (HTR) is widely used as a preclinical assay for the hallucinogenic potential of compounds, with its utility based on 5HT 2A R activation. Here, we examine how the polypharmacological agonists lisuride and lysergic…
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