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WASTE Journal

Browse the failure-mode index

19,843 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Determining the Minimal Number of Passive Hip and Knee Joint Movement Repetitions Recommended for the Stiff Rectus Femoris Muscle Due to Osgood-Schlatter Disease.

Ikeda N, Yoshikawa A, Yamaguchi S et al. · 2026 · Children (Basel, Switzerland)

Background/objectives Osgood-Schlatter disease (OSD) is a common overuse condition in adolescents characterized by increased stiffness of the rectus femoris muscle, which contributes to pain and functional limitations around the knee. We…

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Negative / Null Result ReportMedicine

Vilobelimab to improve clinical outcomes in moderate-to-severe hidradenitis suppurativa through an adjunctive effect on draining tunnels: results of the SHINE double-blind placebo-controlled randomized trial.

Giamarellos-Bourboulis EJ, Jemec GBE, Prens EP et al. · 2026 · The British journal of dermatology

Background The results of a previous phase IIa trial suggested efficacy of the anti-C5a compound vilobelimab in a small number of patients with severe hidradenitis suppurativa (HS) refractory to adalimumab treatment. Objectives To study…

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Negative / Null Result ReportOpen accessMedicine

Cost-Effectiveness of an Antibacterial Envelope in Patients at High Risk of Cardiac Implantable Electronic Device Infection in the Australian Public Healthcare System.

Hill M, Khalaj BH, Shawon MSR et al. · 2026 · Journal of arrhythmia

Background The Worldwide Randomized Antibiotic Envelope Infection Prevention Trial (WRAP-IT) demonstrated a 40% reduction of major cardiac implantable electronic device (CIED) infection with the use of an absorbable antibacterial envelope…

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Negative / Null Result Report

Impact of an Integrated Intervention Package During Preconception, Pregnancy, and Early Childhood on inflammation, IGF-1, IGFBP3 during first 6 months of life: Findings from the WINGS Randomized Controlled Trial

Chowdhury R, Maiti U, Devi S et al. · 2025 · Preprint

Background Early-life interventions targeting maternal and child health, nutrition, and psychosocial care may influence infant growth and immune development by modulating systemic inflammation and growth factor pathways. However, causal…

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Negative / Null Result ReportOpen accessMedicine

The impact paradox: mixed-methods evaluation of National Institute of Health and Care Research funding for intellectual disability research in the UK.

Goddard N, Dale M, Bishop R et al. · 2026 · BJPsych open

Background People with intellectual disability experience substantial health inequities, including higher multimorbidity, increased healthcare utilisation and markedly reduced life expectancy. High-quality research is essential to address…

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Negative / Null Result ReportMedicine

Exploitation of Saccharomyces cerevisiae as an alternative microencapsulation strategy of thymol via β-glucan based matrix for the development of multilayer LDPE active packaging films - comparison with zeolite- and activated carbon-based carriers.

Giotopoulou I, Stamatis H, Barkoula NM · 2025 · International journal of biological macromolecules

In the current study Saccharomyces cerevisiae (S. cerevisiae) was exploited as an alternative carrier of thymol with the aim of developing multilayer low-density polyethylene (LDPE) films with advanced bioactivity over time. The results…

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Negative / Null Result ReportMedicine

Experimental and clinical evidence on radiofrequency electromagnetic field effects on the blood-brain barrier: a scoping review.

Simsek ET, Sumser K, Mansourinezhad P et al. · 2026 · Physics in medicine and biology

Objective. This scoping review evaluates evidence on whether radiofrequency electromagnetic field (RF-EMF) exposure influences blood-brain barrier (BBB) permeability. Given inconsistent findings across decades of research and expanding…

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Negative / Null Result ReportMedicine

Spectroscopic analysis of the N<sub>2</sub> B<sup>3</sup>Π<sub>g</sub>-A<sup>3</sup>Σ+u in radiation-induced air ionization.

Murzyn CM, Jans ER, Marshall GJ · 2026 · Physical chemistry chemical physics : PCCP

This article presents experimental results from probing atmospheric air irradiated by a Polonium-210 alpha particle source using both optical emission spectroscopy and continuous wave cavity ring down absorption spectroscopy to study the…

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Negative / Null Result Report

Assessing Brain-Behaviour Coupling in Non-invasive Brain Stimulation Using Reliable Change Indices: Evidence from pre-Supplementary Motor Area – right Inferior Frontal Gyrus transcranial Alternating Current Stimulation

Fujiyama H, Wansbrough K, Lebihan B et al. · 2026 · Preprint

Non-invasive brain stimulation (NiBS) studies frequently report exploratory correlations between individual-level changes in neurophysiological and behavioural measures. However, these analyses are typically underpowered and rely on…

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Negative / Null Result Report

Geomagnetic Excursions as CO₂-Null Climate Forcing Events: The Laschamps/Adams Event in Proxy Context and a Comparative Analysis of Brunhes Chron Excursions Against the EPICA Dome C Record

Gray JH · 2026 · Preprint

The Laschamps geomagnetic excursion (~41-42 ka BP) represents the largest geomagnetic field collapse in the past 800,000 years, driving documented megafaunal extinctions, Neanderthal extinction, Northern Hemisphere ice sheet expansion, and…

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Negative / Null Result ReportOpen accessMedicine

Gender Differences in Preoperative Anxiety and the Association with Early Maladaptive Schemas: A Cross-Sectional Correlational Study.

Abdelrazek MN, Mohamed HMM, El-Monshed AH et al. · 2026 · Healthcare (Basel, Switzerland)

Background : Preoperative anxiety is a common and clinically significant response among surgical patients, with prevalence estimates ranging from 30% to over 80% depending on measurement method and surgical context. Early maladaptive…

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Negative / Null Result ReportOpen accessMedicine

Safety of hepatitis E vaccine in pregnancy.

Zhang F, Yang G, Chen Y et al. · 2026 · Virology journal

This comment discusses the critical public health challenge of hepatitis E in pregnancy and highlights the significant safety evidence gap for the HEV239 vaccine in this vulnerable group. Focusing on a landmark study from South Sudan by…

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Negative / Null Result ReportMedicine

Overnight residues of sensorimotor aftereffects and lack of visuospatial aftereffects following a single prism exposure in healthy subjects.

Mizrahi O, Wilf M, Ovadia-Caro S · 2025 · Cortex; a journal devoted to the study of the nervous system and behavior

Prism adaptation (PA) is a visuomotor adaptation paradigm resulting in transient sensorimotor shifts. Previous work shows PA can cause additional changes in higher-level visuospatial representations in healthy subjects. In patients with…

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