20,217 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Buyukkoruk M, Tunccan OG, Yigit S et al. · 2026 · Preprint
Abstract Background: This study aimed to evaluate the effect of the gastrointestinal system multiplex PCR panel (GISP) on the relapse-free survival of ulcerative colitis (UC) both active and in remission patients. Methods: In this…
View details →Palmi S, Arponen O, Murto M et al. · 2026 · JAMA network open
Importance Statin use has been associated with improved survival in patients with breast cancer, but there are no data on the association between statin use and survival in different intrinsic breast cancer subtypes. Objective To assess…
View details →Gunun N, Kaewpila C, Kesorn P et al. · 2026 · Animal bioscience
Objective The aim of this study was to evaluate the effect of the inclusion of tomato pomace silage (TPS) on feed intake, nutrient digestibility, blood parameters, immune response, milk yield, and milk nutritional composition in dairy…
View details →Sunada S, Kuroishi T · 2026 · Journal of oral biosciences
Immunoglobulin A (IgA)-producing cells in the three major murine salivary glands (SGs) were analyzed using flow cytometry. Sublingual glands (SLGs) had significantly higher frequencies of IgA + cells than other SGs. IgA + cells expressed…
View details →Wang M, Wang X, Zeng Y et al. · 2026 · Journal of animal science
This study evaluated the effects of replacing dietary glucose with fructose on intestinal development in weaned pigs and assessed epithelial growth using a small intestinal organoid model. A total of 26 weaned pigs ([Yorkshire × Landrace]…
View details →Shchulkin AV, Chernykh IV, Abalenikhina YV et al. · 2026 · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Objective To compare the effects of Mexidol, Cerebrolysin, and Cortexin on the levels of brain-derived neurotrophic factor (BDNF), tumor necrosis factor-alpha (TNF α ), and apoptosis markers in the rat brain following middle cerebral…
View details →Vicente ACS, Salas-Solis GK, Johnson ML et al. · 2026 · Journal of dairy science
Peas (Pisum sativum L.) have 24% CP and could have the potential to partially replace soybean meal (SBM), which is the most used protein source in dairy diets in the USA. Sprouting can improve nutrient availability via enzymatic and…
View details →Wallbom N, Khansari AR, Sandblom E et al. · 2026 · Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
The trade-off between growth and immunity in fish has been assumed to relate to energetic costs associated with immune functions. Here, we hypothesized that immunization with a bivalent mineral oil-adjuvanted vaccine elevates standard…
View details →Rout M, Blackett P, Sanghera DK · 2026 · Nutrients
Background: Vitamin D (25(OH)D) deficiency affects over one billion people globally and is associated with type 2 diabetes (T2D) and cardiometabolic diseases. However, causal relationships remain unclear, as vitamin D supplementation has…
View details →İren AY, Yiğit E · 2026 · BMC oral health
BACKGROUND: The aim of this in-vitro study was to evaluate the effect of preheating on the flexural strength, flexural modulus and microhardness of several commercially available single-shade universal resin composites (SSURCs). METHODS:…
View details →Kim SJ, Park K, Daher R et al. · 2026 · Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
Objective This study aimed to evaluate the impact of storage temperature and duration on the dimensional stability and mechanical properties of 3D-printed surgical guides. Materials and methods Sixty surgical guides were designed using two…
View details →Toczylowski K, Lewandowski D, Martonik D et al. · 2026 · Preprint
Abstract Multisystem inflammatory syndrome in children (MIS-C) and Kawasaki disease (KD) are pediatric hyperinflammatory conditions with overlapping features, but their molecular basis remains poorly defined. Matrix metalloproteinases…
View details →Stédile EdSN, Galon L, Korchagin J et al. · 2026 · Preprint
In southern Brazil, a large proportion of farmers maintain their fields under fallow conditions during the transition period between summer and winter crops. During this interval, mechanical practices such as chiseling or the introduction…
View details →Lazado CC, Brenne H, Olaisen D et al. · 2026 · Scientific reports
The diplomonad parasite Spironucleus salmonicida causes spironucleosis, a systemic infection characterised by internal haemorrhaging, splenomegaly, and granulomatous lesions in multiple organs. Prevention is the primary control strategy,…
View details →Zhang S, Zheng T, Zhou M et al. · 2026 · Journal of phycology
This study investigates the chemical and morphological responses of two domoic acid (DA)-producing diatoms, Pseudo-nitzschia multiseries and P. fukuyoi, to conspecific chemical cues released from mechanically damaged cells. Cell homogenate…
View details →Setiawan AS, Caesarini M, Musnamirwan IA et al. · 2026 · BMC public health
Background Stunting, a form of chronic malnutrition, is associated with impaired growth and potential changes in salivary function that may increase susceptibility to early childhood caries (ECC). These oral conditions may further…
View details →Yang H, Dai T, Wolf RM · 2026 · NPJ digital medicine
Artificial intelligence (AI) is increasingly used for diagnostic screening. In diabetic retinopathy screening, autonomous AI systems can identify disease without a specialist. However, patient trust in AI remains a challenge, and it…
View details →Roy C, Ouellet DR, Pellerin D et al. · 2026 · Journal of dairy science
The current experiment studied 2 situations proposed to lead to decreased milk protein yield (MPY). First, NRC (2001) predicts that substitution of soybean meal (SBM) by canola meal (CM) decreases MP supply, thereby negatively affecting…
View details →Jing S, Wang J, Cheng S et al. · 2026 · Toxicon : official journal of the International Society on Toxinology
Voltage-gated sodium channels (VGSCs) are emerging therapeutic targets for cancers including neural tumors such as neuroblastomas and gliomas. BmK IT2, a neurotoxic polypeptide from the scorpion Buthus martensii Karsch, is a known…
View details →Onu CJ, Adu M, Jabbar D et al. · 2026 · Biochimica et biophysica acta. Molecular and cell biology of lipids
Inositol is an essential metabolite required for membrane biogenesis, cell signaling and trafficking, and gene expression. Its importance is underscored by the fact that inositol depletion leads to death in eukaryotic cells ranging from…
View details →Tiburcio MA, Cali MP, Pereira LMB et al. · 2026 · Dalton transactions (Cambridge, England : 2003)
Amyloid deposits of amyloid-β (Aβ) and hyperphosphorylated tau are pathological hallmarks of Alzheimer's disease (AD), which accounts for most dementia cases worldwide. This study investigates the effect of the complex [Ru(phen) 2 (pNDIp)]…
View details →Gaudeul A, Krawczyk M · 2026 · Preprint
Abstract We conducted an online experiment with 3420 participants in Bulgaria, Germany and Spain to evaluate the consequences of digital access to food information via QR codes. Participants made incentivized choices between food products…
View details →Lu X, Ferraz GA, Sivakumar S et al. · 2026 · Preprint
ABSTRACT Aging is associated with a gradual and progressive decline in skeletal muscle mass and strength known as sarcopenia, which has been attributed to chronic low-grade inflammation. Dietary long-chain polyunsaturated fatty acids…
View details →Cherkasova M, Assi A, Craw M et al. · 2026 · Preprint
Objective: A prominent feature of land-based and online slot machines is audiovisual feedback that accompanies winning outcomes. Prior laboratory work suggests that this design feature may influence game experience, facilitate immersion,…
View details →Sevim B · 2026 · Tropical animal health and production
This study investigated the effects of dietary supplementation with fermented black garlic powder on performance, carcass characteristics, serum parameters, immunological responses and antioxidant status in male Japanese quail. A total of…
View details →Silva ACD, Varela Junior AS, França RT et al. · 2026 · Cell biochemistry and function
Lectins are carbohydrate-binding proteins that recognize specific glycan patterns on cell surfaces and have been increasingly explored as analytical tools in reproductive biology. This study characterized the interaction of a lectin…
View details →Wang NN, Luo CJ, Liu LG et al. · 2026 · Ying yong sheng tai xue bao = The journal of applied ecology
Litter decomposition is a core process regulating the formation and stability of soil organic carbon. Under the background of climate warming, the intrinsic mechanisms by which the expansion of alpine shrubs affects carbon balance of…
View details →Sanei A, Asgarian FS, Ebrahiminezhad M · 2026 · Preprint
Abstract Background The lack of studies and sometimes conflicting results in this field, has required that this study be conducted with the aim of improving treatment results in dental health care system. Methods The present study was…
View details →Suarez-Baquero DE, Boido D, Assali A et al. · 2026 · Preprint
Abstract In brain gray matter, neurovascular coupling (NVC) maintains brain metabolism homeostasis by modulating blood flow according to neuronal activity. In white matter, the energy cost of information transmission along myelinated axons…
View details →Tan X, Ding Z · 2026 · Preprint
Astrocytes are the most abundant glial cells in the brain and an integrative component of the neural network. Studies have shown that ethanol altered expression of an astrocyte marker, i.e., glial fibrillary acidic protein (GFAP), in two…
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