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Browse the failure-mode index

19,843 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

The Lack of Association of Infant Gender with Postpartum Depression and Breastfeeding Duration.

Akkurt B, Bülez A · 2025 · Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine

Objective: This study aimed to investigate the association between infant gender and both postpartum depression and breastfeeding duration at multiple time points during the postpartum period. Methods: A prospective longitudinal study was…

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Negative / Null Result ReportOpen accessMedicine

Optimal duration of neoadjuvant chemotherapy prior to CRS ± HIPEC for colorectal cancer: An assessment of survival and postoperative outcomes.

Bennett FJ, Oppat KM, Zaidi MY et al. · 2026 · Surgical oncology insight

Background Cytoreductive surgery (CRS) with or without heated intraperitoneal chemotherapy (HIPEC) represents a viable therapy for select patients with colorectal cancer (CRC) peritoneal metastases. Given recurrence rates, challenges…

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Negative / Null Result ReportOpen accessMedicine

Weight and sleep health in OSA: exploring their link.

Beatty CJ, Landry SA, Mann DL et al. · 2026 · Frontiers in sleep

Objectives Weight loss is often recommended for individuals with obesity and OSA, however, weight loss is particularly hard for this population. This study investigates how weight and weight change are associated with sleep health in…

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Negative / Null Result ReportMedicine

Unveiling connections: bisphenol A and vitamin D dynamics in breast milk among healthy lactating mothers.

Cinkilli Aktağ E, Yalçin SS, Yіrün A et al. · 2025 · International journal of environmental health research

Bisphenol A (BPA) has negative impact on human health. This study aims to explore the association between the levels of BPA and 25(OH) vitamin D in breastmilk. BPA exposure and vitamin D sources were recorded on the study form. Breastmilk…

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Negative / Null Result ReportOpen accessMedicine

Nocturnal gastro-oesophageal reflux and pulmonary abnormalities on chest CT in a general population: the Swedish CArdioPulmonary BioImage Study.

Emilsson ÖI, Malinovschi A, Johnsson Å et al. · 2025 · Thorax

Background Nocturnal gastro-oesophageal reflux (nGER) is common in people with respiratory diseases, but its association with pulmonary abnormalities is not known. Aim Investigate the association between nGER and pulmonary abnormalities on…

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Negative / Null Result ReportOpen accessMedicine

Association between neutrophil extracellular traps, the Von Willebrand factor axis, and clinical outcome in stable coronary artery disease.

Bratseth V, Kindberg KM, Warlo EMK et al. · 2026 · Frontiers in cardiovascular medicine

Introduction Coronary artery disease (CAD) is the clinical manifestation of atherosclerosis, an inflammatory disorder of the coronary arteries, characterized by endothelial dysfunction, lipid accumulation, immune activation, and formation…

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Negative / Null Result ReportMedicine

Lack of Association Between Dietary Fiber Intake and Kidney Failure Among Patients With Chronic Kidney Disease: The Chronic Kidney Disease-Japan Cohort Study.

Hattori K, Sakaguchi Y, Isaka Y et al. · 2025 · Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation

Objective It remains unclear whether dietary fiber intake improves kidney outcome. The objective of our study was to examine the association between dietary fiber intake and the risk of kidney failure among patients with proteinuric…

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Negative / Null Result ReportMedicine

SARS-CoV-2 Vaccination and Disorders of Menstruation: A Population-Based Cohort Study.

Velez MP, Treacy K, Shellenberger J et al. · 2025 · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC

This population-based study evaluated the association between SARS-CoV-2 vaccination and disorders of menstruation among all women in Ontario aged 18-44 years. Study exposure was receipt of a first dose of any SARS-CoV-2 vaccine from…

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Negative / Null Result ReportMedicine

The role of susceptibility weighted imaging as a substitute to post-contrast T1-weighed images in detection of active multiple sclerosis lesions.

Rashad Ali F, Teiba MK, Sheha AS et al. · 2026 · Clinical radiology

Background and purpose Magnetic susceptibility levels of multiple sclerosis plaques increase as they convert from the active enhancing stage to the chronic or inactive nonenhancing stages. The purpose of our study was to discern whether a…

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Negative / Null Result ReportOpen accessMedicine

Evaluation of the therapeutic value of conventional transpedal lymphography for the treatment of inguinal lymphatic fistulas after lymphadenectomy.

Wolfram C, Vogl TJ, Eichler K et al. · 2026 · CVIR endovascular

Purpose To evaluate therapeutic effectiveness and safety of lipiodol-based conservative transpedal lymphangiography in sealing persistent inguinal lymphatic fistulas after lymphadenectomy and to determine whether therapeutic success is…

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Negative / Null Result ReportOpen accessMedicine

Distribution of Plasmodium falciparum apical membrane antigen-1 cluster one loop haplotypes and their association with malaria symptoms in Bandiagara, Mali.

Ouattara A, Adams M, Niangaly A et al. · 2026 · BMC infectious diseases

Although overall malaria incidence has decreased sharply over the past two decades, progress has stalled since 2015. The human host maintains a complex set of interactions with Plasmodium falciparum, the parasite species causing most…

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Negative / Null Result ReportOpen accessMedicine

Lack of concordance among infant social attention measures.

Viktorsson C, Astor K · 2026 · Scientific reports

Infants’ tendency to focus on socially relevant cues is commonly referred to as ‘social attention’ and is often conceptualized as a unified construct. However, few studies have examined the concordance among measures that fall under this…

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Negative / Null Result ReportMedicine

Long-term Ambient Air Pollution Exposure and Coronary Calcium Score in Men: Insights from the DANCAVAS Study.

Mohamed RA, Peronard Mayntz S, Møller JK et al. · 2025 · European journal of preventive cardiology

Aims This study assessed the relationship between air pollution exposure, fine particulate matter ≤2.5 µm (PM2.5) and nitrogen dioxide (NO2), and coronary calcium score (CCS) in a cohort of 60-75-year-old men from the Danish Cardiovascular…

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Negative / Null Result ReportMedicine

Physical activity and health-related quality of life among men with prostate cancer living in remote areas of Quebec A cross-sectional, observational study.

Gendron MP, El-Haouly A · 2025 · Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Introduction The majority (97.5%) of men with prostate cancer (PCa) live for at least five years after diagnosis. The health-related quality of life (HRQoL) of such men is affected by the adverse effects of treatment. Men living in remote…

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Negative / Null Result ReportMedicine

Impact of Lordosis Distribution Index on Proximal Junctional Kyphosis and Clinical Outcomes in Patients Undergoing Thoracolumbar Fusion for Degenerative Flatback Syndrome.

Park JS, Kang DH, Lee CS et al. · 2025 · Spine

Study design Retrospective study using prospectively collected data. Objective To investigate the impact of the lordosis distribution index (LDI) on proximal junctional kyphosis (PJK) and clinical outcomes in patients with degenerative…

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Negative / Null Result ReportMedicine

Academic and Pre-Medical Advising Factors Associated with Admission to the John A. Burns School of Medicine Among Premedical Students at the University of Hawai'i at Mānoa.

Hosoda KK, Shiroma KY, Lee PM et al. · 2026 · Hawai'i journal of health & social welfare

The Medical School Hotline of the University of Hawai'i John A. Burns School of Medicine was founded in 1993, by Satoru Izutu PhD (former vice-dean of UH JABSOM). It is edited by Kathleen Kihmm Connolly PhD, HJH&W Contributing Editor.…

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