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19,843 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Carotid Plaque Characteristics Evaluation on DUS and MDCTA: Interobserver and Intermodality Agreement in a Single-Center Study.

Mutavdzic P, Kokovic T, Gakovic B et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : Carotid artery stenosis has traditionally guided therapeutic decision-making; however, plaque morphology and composition are increasingly recognized as more reliable indicators of cerebrovascular risk than…

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Negative / Null Result ReportMedicine

[Comparison between methods to estimate total body fat mass in triathletes: dual X-ray absorptiometry, bioelectrical impedance and anthropometric equations].

Herrera-Torres OA, Flores-Zapata J, Ferreyro-Bravo F · 2026 · Nutricion hospitalaria

Introduction Introduction: the estimation of body fat mass (FM) can be performed using different methods. Although Dual-Energy X-ray Absorptiometry (DXA) is considered the reference technique due to its precision and reproducibility, its…

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Negative / Null Result ReportOpen accessMedicine

Correlations between inflammatory biomarkers and clinicopathological features in surgically resected thymic epithelial tumors: implications for preoperative diagnosis.

Fu J, Han P, Xu J et al. · 2026 · PeerJ

Objective This study aimed to analyze the correlations between pathological characteristics, risk factors, and inflammatory biomarkers in patients with thymic epithelial tumors (TETs) undergoing surgical resection. Methods A retrospective…

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Negative / Null Result ReportMedicine

The association between a sepsis diagnosis, demographic factors, and health-related quality of life in survivors at 180 days following critical illness.

De Silva S, Charles-Nelson A, McQuilten Z et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses

Background Survivors of critical illness often have poor health-related quality of life (HRQoL). However, it is unclear what factors are associated with changes in HRQoL after critical illness. Objectives The aim of this study was to…

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Negative / Null Result ReportMedicine

Face-To-Face Vs. Online Behavioral Parent Training for Young Children with ADHD: Child and Parent Outcomes.

DuPaul GJ, Kern L, Dever BV et al. · 2026 · Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53

Objective Behavioral parent training is a first-line psychosocial intervention for young children with Attention-Deficit/Hyperactivity Disorder. Traditional face-to-face delivery is limited by access to therapists, feasibility, and/or…

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Negative / Null Result ReportOpen accessMedicine

The rise and fall of glucocorticoids and immunosuppressants in idiopathic pulmonary fibrosis: a historical paradigm shift driven by mechanistic understanding.

Wen B, Wu X, Ma X et al. · 2026 · Frontiers in immunology

The therapeutic strategy for Idiopathic Pulmonary Fibrosis (IPF) has undergone a fundamental transformation over recent decades. Combination therapy with glucocorticoids and immunosuppressants, particularly the "triple therapy" regimen…

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Negative / Null Result ReportMedicine

PD-L1 subpopulations of metastatic urothelial carcinoma demonstrate heterogeneity to chemotherapy: an integrated analysis of digitized trial results.

Zhou J, Jiang X, Liu Q et al. · 2026 · Cancer metastasis reviews

Efforts to translate advances in immunology into anti-cancer immunotherapies have progressed rapidly in recent years. Six antibodies acting on programmed death ligand 1 or programmed death 1 pathways were approved in 75 cancer indications…

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Negative / Null Result ReportMedicine

Optimal endoscopic treatment for rectal neuroendocrine tumors, confirmed after forceps biopsy: a Korean Association for the Study of Intestinal Diseases multicenter, randomized noninferiority trial.

Gweon TG, Kim SJ, Myung DS et al. · 2026 · Gastrointestinal endoscopy

Background and aims Insufficient submucosal lifting because of pretreatment with forceps biopsy frequently complicates endoscopic treatment of rectal neuroendocrine tumors (NETs) and potentially affects procedural outcomes. Despite…

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Negative / Null Result ReportOpen accessMedicine

Impact of Endocuff addition to real-time computer-aided detection of colorectal neoplasia in a randomised tandem colonoscopy trial.

Stasinos I, Voulgaris T, Kouimtsidis IA et al. · 2026 · World journal of gastrointestinal pharmacology and therapeutics

Background Risk of post colonoscopy colorectal cancer is related to adenoma miss rate (AMR) during colonoscopy. Artificial intelligence (AI) and Endocuff Vision are tools both used to increase adenoma detection rate (ADR). Aim To assess…

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Negative / Null Result ReportOpen accessMedicine

Vitamin D in Endocrine Disorders: A Broad Overview of Evidence in Musculoskeletal, Thyroid, Parathyroid, and Reproductive Disorders.

Lengyel B, Armos R, Bojtor B et al. · 2025 · Pharmaceuticals (Basel, Switzerland)

Vitamin D is well established for its skeletal effects, being a cornerstone of several endocrine disorders. In recent years, it has come under investigation as a potential disease-modifying drug in several endocrine disorders through its…

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Negative / Null Result ReportMedicine

Frontline Pembrolizumab or Methotrexate in Elderly, Frail, or Cisplatin-Ineligible Patients with Relapsed or Metastatic Squamous Cell Carcinoma of the Head and Neck: Results of the Randomized Phase 2 Study ELDORANDO (AIO-KHT-0115).

Klinghammer K, Graeven U, Ivanyi P et al. · 2026 · Oncology research and treatment

Introduction Elderly, frail, or cisplatin-ineligible patients with recurrent or metastatic squamous cell carcinoma of the head and neck (R/M HNSCC) have a poor prognosis. To date, no standard of care has been defined for this population.…

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Negative / Null Result ReportMedicine

Comparative Survival Outcomes of Total Hysterectomy Versus Radical Hysterectomy in Gastric-Type Endocervical Adenocarcinoma: A SEER Database Analysis.

Ge Y, Wang X, Zhang Y et al. · 2026 · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC

Objectives This study aims to assess the efficacy of total hysterectomy versus radical hysterectomy in the treatment of gastric-type endocervical adenocarcinoma (GEA). Methods Patients diagnosed with GEA from 2001 to 2021 were derived from…

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Negative / Null Result ReportMedicine

Anti-inflammatory agents for the management of COPD - Quo Vadis?

Bakakos A, Sotiropoulou Z, Anagnostopoulos N et al. · 2025 · Respiratory medicine

Chronic obstructive pulmonary disease (COPD) remains a leading cause of morbidity and mortality around the globe. Its main characteristics are persistent respiratory symptoms and progressive airflow limitation, both of which are driven by…

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Negative / Null Result ReportOpen accessMedicine

A Retrospective Study of a Postoperative Inflammation-Based Score for Predicting Disease-Free Survival in Locally Advanced Rectal Cancer After Neoadjuvant Chemoradiotherapy.

Yang Q, Li J, Ding L et al. · 2026 · Cancer management and research

Background Growing research findings highlight the potential of inflammatory markers measured after surgery as prognostic indicators for survival outcomes in rectal carcinoma patients. However, their precise clinical significance remains…

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Negative / Null Result ReportOpen accessMedicine

The fluid paradox: dissociation between clinical and ultrasound parameters of fluid overload - results of the INCIVEX exploratory study.

Wong A, Cheah K, Papathanakos G et al. · 2026 · Anaesthesiology intensive therapy

Introduction Fluid management in critically ill patients relies on clinical assessment, fluid balance calculations and, increasingly, point-of-care ultrasound. However, the rela-tionships between these assessment modalities remain poorly…

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Negative / Null Result ReportMedicine

Survival outcomes of the use of adjuvant chemotherapy in resected esophagus cancer after neoadjuvant chemoradiotherapy.

Ke TM, Lin T, Chow WH et al. · 2026 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Introduction Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is the standard treatment for esophageal cancer, but the role of adjuvant chemotherapy remains unclear. This study investigates the survival benefits of adjuvant…

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Negative / Null Result ReportMedicine

Does the Timing of Lysis of Adhesions After Anterior Cruciate Ligament Reconstruction Affect Final Range of Motion?

Schneble CA, Miltenberg B, Jurgensmeier K et al. · 2025 · The American journal of sports medicine

Background Arthrofibrosis is seen in 1.7% to 38% of patients after anterior cruciate ligament reconstruction (ACLR) and has been associated with worse postoperative patient-reported outcomes. There are limited data regarding the optimal…

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