19,840 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Unubol N, Ayaş M, Uyar NY et al. · 2025 · Microorganisms
In recent years, the World Health Organization has highlighted biofilm-derived multidrug-resistant bacteria as a critical threat to both global health and the environment. Although various testing methods are available, crystal violet and…
View details →AL-Saeedi A, Abdulamir AS, Aufi IM et al. · 2025 · Preprint
Abstract Background The widespread use of accurate real-time RT-PCR tests for community individuals is a critical approach to managing the disease and reducing COVID-19 transmission effectively. In addition, serological ELISA assays are…
View details →Mukherjee S, Fujiwara Y, Fountzilas C et al. · 2025 · Cancer medicine
Background Preoperative chemoradiation (CRT) followed by surgery for localized esophageal and gastroesophageal junction adenocarcinoma (EGAC) is a standard of care with a pathologic complete response (pCR) rate of 20%. We evaluated a novel…
View details →Fu Q, Chen Y, Huang D et al. · 2023 · Annals of surgical oncology
Background Folinic acid, fluorouracil, irinotecan, and oxaliplatin (FOLFIRINOX) or modified FOLFIRINOX (mFFX) is the first-line standard of care for metastatic pancreatic adenocarcinoma; effective and safe treatment strategies are needed…
View details →Hiester A, Che Y, Lusch A et al. · 2023 · European urology
Background Primary retroperitoneal lymph node dissection (RPLND) for clinical stage (CS) IIA/B seminoma without adjuvant treatment is an experimental treatment to avoid radiotherapy- or chemotherapy-related toxicity from standard…
View details →Schwartz A, Mikati S, Knipper F et al. · 2025 · Applied biosafety : journal of the American Biological Safety Association
Background The COVID-19 pandemic highlighted critical shortages in personal protective equipment (PPE), particularly respirators, which limited healthcare workers' safety worldwide. Decontamination and reuse of PPE, including powered-air…
View details →Ahogni I, Avanon H, Hueha C et al. · 2026 · Malaria journal
Background Accurate interpretation and recording of malaria rapid diagnostic tests (RDTs) are critical for case management and surveillance in malaria-endemic settings. In Benin, where over 90% of malaria diagnoses rely on RDTs, concerns…
View details →Bulut C, Arslan Z, Aydoğdu M et al. · 2026 · Forensic science international
Rising global alcohol consumption is a major public health and safety concern. Over the last decade, undeclared alcohol consumption has increasingly come into focus due to high inflation that has led many individuals to resort to unhealthy…
View details →Kavunga-Membo H, Chi HF, Emperador DM et al. · 2026 · The Lancet. Infectious diseases
Background Mpox has spread to 36 countries in Africa, yet many face challenges achieving nationwide PCR-based testing due to cost and limited access in remote and rural areas. Point-of-care antigen-based rapid diagnostic tests (RDTs) might…
View details →Watanabe T, Hirano T · 2026 · Clinical medicine insights. Pediatrics
Objective The importance and effectiveness of Newborn hearing screening (NHS) have been widely recognized. However, there are a few cases of false-negative NHS results. Hearing loss in children causes various disorders. Therefore,…
View details →Mangiaterra T, Chabay P, Bellan C et al. · 2026 · Frontiers in immunology
Epstein-Barr virus (EBV) infects more than 90% of the global population and is etiologically linked to a wide spectrum of lymphoid and epithelial malignancies. Although its role as an oncogenic virus is well established, the mechanisms…
View details →Wang X, Albayda J, Paik JJ et al. · 2025 · Rheumatology (Oxford, England)
Objective This study aims to evaluate the diagnostic accuracy of CA-125 and PET/CT in detecting cancer among adult patients with idiopathic inflammatory myopathy (IIM). Methods We conducted a retrospective study of a single-centre cohort…
View details →Mann L, Samp P, Schäefer JH et al. · 2025 · Preprint
Background: / Objectives; After negative results of the SAMMPRIS-trial the indication for endovascular treatment of atherosclerotic intracranial artery stenosis (ICAS) was widely restricted. It was the aim of our study to report whether…
View details →Kimura K, Kuwata T, Hiraoka Y et al. · 2026 · Journal of human genetics
Multigene panel testing (MGPT) is increasingly used for diagnosing hereditary cancers; however, its application in cascade testing remains limited, and the psychological impact on unaffected relatives is not well understood. This…
View details →Blasich NP, Adelekan AM · 2026 · Health science reports
Background Point-of-care rapid diagnostic testing plays a critical role in HIV detection and timely linkage to care, particularly in decentralized healthcare settings. To support testing reliability, the National Health Laboratory Service…
View details →Uyanık G, Yüksel M, Abay M et al. · 2026 · Veterinary journal (London, England : 1997)
The present study aimed to determine the diagnostic accuracy of the commercial Alertys OnFarm Pregnancy Test (AOPT) based on pregnancy-associated glycoprotein (PAG) for early pregnancy diagnosis in ewes. A total of 100 multiparous Awassi…
View details →Zhang J, Hu Y, Dong P et al. · 2025 · Diagnostics (Basel, Switzerland)
Sarcoidosis is a rare multisystem inflammatory disease characterized by non-necrotizing granulomas, typically affecting the lungs, lymph nodes, skin, and bones. Due to its extreme clinical heterogeneity, diagnosis remains challenging.…
View details →Pandey P, Bir R, Chatterjee K et al. · 2026 · Iranian journal of microbiology
Background and objectives Sepsis is a life threatening condition caused by a dysregulated host response to infection and is associated with high morbidity and mortality worldwide. Early bacterial detection and therapy with antibiotics…
View details →Samkange A, Chitanga S, Mbiri P et al. · 2025 · The Onderstepoort journal of veterinary research
Neosporosis is a leading cause of bovine abortions worldwide, with a substantial economic impact because of reproductive losses, costing the cattle industry billions of dollars annually. Despite the global significance of Neospora caninum,…
View details →Lis K · 2025 · Life (Basel, Switzerland)
Vitamin B1 (thiamine) is a water-soluble B vitamin. As a cofactor of many enzymes, it is essential for the proper functioning of many body systems and organs, including metabolic and energy metabolism. In extreme cases, vitamin B1…
View details →Steinhauer R, Kübler E, Gaugler S et al. · 2026 · Journal of virological methods
Dried blood spots (DBS) constitute a stable, cost-efficient sampling matrix that can be collected in a minimally invasive manner. Although widely adopted in human medicine, their use in veterinary diagnostics remains limited. This study…
View details →Rodrigues NJL, França DA, Menozzi BD et al. · 2026 · Pathogens (Basel, Switzerland)
Comparative evaluations of different serological methods for the diagnosis of toxoplasmosis in pregnant women remain limited, and the performance of indirect immunofluorescence assay (IFA), modified agglutination test (MAT), and…
View details →Cheng X, Huang H, Fan Z et al. · 2026 · BMJ open ophthalmology
Objective To evaluate the efficacy and safety of portable, cost-effective manual thermal pulsation as a single therapy for meibomian gland dysfunction (MGD) and to compare the microbiota and lipid composition in subjects with different…
View details →Hayman NT, Pandelides Z, Colvin MA et al. · 2026 · Environmental toxicology and chemistry
A lack of marine specific data results in challenges to assessing site-specific ecological risks and developing marine water quality criteria for per- and polyfluoroalkyl substances (PFAS). Here, the toxicity and bioaccumulation of…
View details →De Groote W, Taremwa Y, Duttine A et al. · 2026 · International journal of environmental research and public health
In Uganda, in 2019, 6.8 million people experienced health conditions that are amenable to rehabilitation. This is largely due to musculoskeletal disorders such as low back pain (LBP). Measuring effective coverage of rehabilitation means…
View details →Aljuaid M, Alsiraj K · 2026 · Annals of the ICRP
This is a national study about the occupational Radiation doses for medical workers in the Kingdom of Saudi Arabia which covers the period since the establishment of the Nuclear and Radiological Regulatory Commission (NRRC). The study aims…
View details →Büyüksefil M, Çimen Ü, Şimşek Derelioğlu S et al. · 2026 · Oral health & preventive dentistry
Purpose Effective communication with paediatric patients is one of the cornerstones of paediatric dentistry. Strong communication skills play a critical role in reducing dental anxiety, enhancing patient satisfaction, and facilitating the…
View details →Choi JY, Song WS, Won YK et al. · 2026 · Korean journal of ophthalmology : KJO
Purpose To compare the effective phacoemulsification time used in cataract surgery and postoperative outcomes between the Veritas and the Centurion Vision System. Methods A retrospective analysis was conducted on 90 eyes from 82 patients…
View details →Jacobs S, Edelhoff H, Ebert C et al. · 2026 · BMC ecology and evolution
Effective population size (Ne) is a fundamental parameter in conservation genetics, providing relevant information on the adaptability and long-term viability of populations. In contrast, wildlife management strategies, particularly for…
View details →Leung A, Koo J · 2026 · CNS drugs
Dermatological delusional disorders, such as delusional infestation (DI), are a unique type of psychosis in which the patient experiences specific delusions, such as parasites or inorganic materials that come out of their skin. Originally,…
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