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Browse the failure-mode index

19,830 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Effect of duration of feeding a sorghum silage-based backgrounding diet in an intense postweaning production system for Nellore bulls on growth performance

Pucetti P, Silva JT, Alves JB et al. · 2026 · Animal Feed Science and Technology.

The objective of this study was to evaluate the effects of different backgrounding durations in an intense postweaning production system for Nellore bulls, as compared with immediate adaptation to a corn-based finishing diet. Forty bulls…

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Negative / Null Result ReportMedicine

Influence of accent and learning styles on online animation learning.

Zhang Y, Zhang H, Wang Y et al. · 2026 · Cognitive processing

The influence of the interaction between accent and learning styles on learners' learning is an important issue to be considered in online animation design and application. The objective of this study is to reveal the effects of accent and…

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Negative / Null Result ReportMedicine

Inclusion of rapeseed cake or oil in the diet of beef cattle reduces enteric methane emissions without affecting animal performance.

Folliard NT, Waters SM, Roskam E et al. · 2026 · Animal : an international journal of animal bioscience

The global methane (CH 4 ) pledge aims to reduce anthropogenic CH 4 emissions by 30% by 2030. Oilseed rape (Brassica napus L), a break crop with 40 million ha cultivated globally in 2022, produces fatty acid-rich by-products that could…

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Negative / Null Result ReportMedicine

Outcomes and Complications After LUMiC<sup>®</sup> Endoprosthetic Reconstruction of Periacetabular Defects-A Retrospective Cohort Analysis.

Niemann AS, Ramon R, Mayor J et al. · 2026 · Life (Basel, Switzerland)

(1) Background: The reconstruction of periacetabular defects after tumor resection remains one of the most challenging procedures in orthopaedic oncology. The modular LUMiC ® system was designed to improve fixation stability and reduce…

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Negative / Null Result ReportMedicine

Sex, Race, and Ethnicity in National Institutes of Health Career Development Award Submissions and Success: A 20-Year Retrospective Cohort Study.

Koumpias AM, Kirch M, Steppe E et al. · 2026 · Journal of women's health (2002)

Background Obtaining a National Institutes of Health (NIH) career development (K) award is a pivotal milestone for early-career faculty, contributing not only to individual career progression but also to the diversity of the biomedical…

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Negative / Null Result ReportMedicine

Comparison of explosive power, balance and muscle morphology in female volleyball players with and without chronic ankle instability.

Comlekci M, Yıldız AE, Demirel A · 2026 · BMC sports science, medicine & rehabilitation

Background Ankle sprains are among the most common injuries in athletes, accounting for approximately 80% of all athletic injuries. Recurrent ankle sprains often progress to chronic ankle instability (CAI), which can impair athletic…

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Negative / Null Result ReportMedicine

Efficacy and safety of morning or evening antihypertensive drug administration on albuminuria in hypertensive patients: an open-label pilot randomized controlled trial.

Trakarnvanich T, Nochaiwong S, Ruengorn C et al. · 2026 · Scientific reports

To date, little is known regarding the treatment effects of different timed-dosing antihypertensive medications among hypertensive patients with albuminuria. We aimed to investigate whether morning or evening dosing of antihypertensive…

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Negative / Null Result ReportMedicine

Human Steering Control Under Unpredictable Disturbances.

Liu JY, Cooke JRH, Selen LPJ et al. · 2026 · The European journal of neuroscience

There are multiple methods for controlling dynamical systems under external disturbances, with some emphasizing robust performance and others prioritizing efficiency. Here, we characterized the control strategies of human steering behavior…

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Negative / Null Result ReportOpen accessMedicine

Effects of homeopathic remedy supplementation on performance, blood parameters, and behavior of pigs under vaccination and regrouping stress conditions.

Lee H, Sung JY, Son J et al. · 2026 · Journal of animal science and technology

In the modern swine production systems, pigs are often challenged with regrouping and vaccination, which may negatively affect growth performance and behavior of pigs. The objective was to test the hypothesis that a supplemental…

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Negative / Null Result ReportMedicine

Therapeutic targeting of bleomycin-induced pulmonary fibrosis by human bone marrow mesenchymal stem cell-derived extracellular vesicles and/or pirfenidone: Impact of sex in mature adult mice.

Charoenphannathon JS, Royce SG, Higham Y et al. · 2026 · British journal of pharmacology

Background and purpose Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited therapeutic options. This study compared the therapeutic effects of bone marrow mesenchymal stem cell-derived extracellular vesicles…

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Negative / Null Result ReportMedicine

Effects of Synbiotic Supplementation on Blood and Urinary Concentrations of Factors Related to Kidney Stone Formation in Overweight or Obese Patients with Hyperoxaluria: A Randomized Controlled Trial.

Maddahi N, Zamani B, Nadjarzadeh A et al. · 2026 · Urology journal

Purpose This study investigated the impact of synbiotics on blood and urinary concentrations of factors related to kidney stone formation in overweight or obese patients with hyperoxaluria. Materials and methods A randomized double-blind…

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Negative / Null Result ReportMedicine

Simultaneous Assessment of Calcium Signaling and Mitochondria Activity in Human Platelets Using Continuous Flow Cytometry.

Mishukov AA, Ignatova AA, Ogneva AL et al. · 2026 · Cytometry. Part A : the journal of the International Society for Analytical Cytology

Increasing evidence suggests connection between mitochondrial dysfunction and platelet-related disorders, necessitating developing of a high throughput method for assessing the functioning of mitochondria in platelets. Here we develop an…

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Negative / Null Result ReportOpen accessMedicine

Effects of tocilizumab on neutrophil gelatinase-associated lipocalin following out-of-hospital cardiac arrest, and its prognostic value.

Alaoui-Ismaili Z, Grand J, Frydland M et al. · 2026 · Resuscitation plus

Background Early risk assessment is crucial in comatose survivors of out-of-hospital cardiac arrest (OHCA) for timely resource allocation and initiation of interventions. Neutrophil gelatinase-associated lipocalin (NGAL) is an inflammatory…

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Negative / Null Result ReportMedicine

Metabolic and endocrinological effects of weekly growth hormone replacement therapy with somapacitan in patients with adult growth hormone deficiency after switching from daily growth hormone replacement therapy: A real-world exploratory cohort study.

Abe I, Kubo K, Fujita Y et al. · 2026 · Drug discoveries & therapeutics

The metabolic and endocrinological effects in patients with adult growth hormone deficiency (AGHD) who switched from daily growth hormone (GH) replacement therapy to weekly GH replacement therapy with somapacitan were evaluated and…

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