19,830 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Lee CO, Park SY, Yun Y et al. · 2026 · Acta neurochirurgica
Objective Glioblastoma (GBM) incidence increases with age, and its etiologies may differ between young and elderly patients. This study aimed to investigate genetic differences between young and elderly GBM patients using next-generation…
View details →Rapčan R, Kočan L, Witkovsky V et al. · 2026 · Preprint
Abstract Objective Endoscopic facet denervation (ED) and percutaneous cryoneurolysis (Cryo) have emerged as alternative interventional treatments for lumbar facet joint–mediated pain; however, comparative long-term outcome data remain…
View details →Virta L, Engström-Öst J · 2026 · Ecology and evolution
The effects of elevated temperature are pronounced in high latitudes where warming is faster than the global average. It is unclear how warming and other simultaneous stressors will affect the functioning of trophic levels. To study the…
View details →Vandenbossche V, Valcke M, Maldoy M et al. · 2026 · Anatomical sciences education
Digital media have reshaped anatomy education through the integration of virtual three-dimensional models. Techniques such as surface scanning, enable the development of highly photorealistic anatomical models; however, evidence regarding…
View details →Yahata A, Nakamoto N, Oiwa H · 2026 · Rheumatology international
To investigate the clinical characteristics of muscle-dominant ANCA-associated vasculitis (muscle-dominant AAV) in a consecutive single-center cohort. We retrospectively analyzed consecutive patients newly diagnosed with microscopic…
View details →León-Lloreda A, Muñoz-Sánchez B, Polonio-González M et al. · 2026 · Preprint
INTRODUCTION: Delayed initiation of mepolizumab may influence long-term disease control and the achievement of clinical and functional outcomes in patients with uncontrolled severe asthma (SUA), but no definitive conclusions have yet been…
View details →Jaramillo Quiceno GA, Sarmiento Riveros PA, Arias Perez RD et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine
Introduction/objectives Residual rotational laxity remains a relevant clinical concern after anterior cruciate ligament (ACL) reconstruction. Combined ACL and anterolateral ligament (ALL) reconstruction has been proposed to improve control…
View details →Eren Hİ, Takım U · 2026 · Clinical psychology & psychotherapy
Adjustment disorder (AD) is characterized by disproportionate emotional and behavioural responses to stressors, often leading to significant functional impairment; however, the psychological mechanisms underlying this impairment remain…
View details →Akter T, Aziz MA, Shahid AB et al. · 2026 · BMC research notes
Objectives Breast cancer is a complex malignancy influenced by both genetic and environmental mechanisms. The WDFY4 gene, predominantly expressed in immune tissues, plays a role in immune regulation. However, its application in relation to…
View details →Uesato Y, Inamine S · 2026 · Journal of laparoendoscopic & advanced surgical techniques. Part A
Background The umbilical port is routinely used for camera insertion and specimen retrieval in laparoscopic cholecystectomy (LC). However, the umbilicus is anatomically vulnerable and may be associated with an increased risk of surgical…
View details →Di Lorenzo G, Melluso M, Rodolico A et al. · 2026 · The journal of allergy and clinical immunology. In practice
Background Allergen immunotherapy (AIT) is the only disease-modifying treatment for grass pollen-induced allergic rhinoconjunctivitis (ARC). Three delivery routes-subcutaneous (SCIT), sublingual drops (SLIT-D), and sublingual tablets…
View details →Baulier C, Zappella N, Grall N et al. · 2026 · Anaesthesia, critical care & pain medicine
Background Recent studies have increasingly questioned the efficacy and safety of piperacillin-tazobactam (TZP) in septic patients, particularly those with healthcare-associated intra-abdominal infections (hcIAI). This study assessed…
View details →Ariza-Torrado IP, Groman-Lupa S, Martínez-Córdoba CJ et al. · 2026 · Journal of vitreoretinal diseases
Purpose: To evaluate functional and structural outcomes after application of a single intravitreal dose of faricimab in patients with chronic retinal diseases. Methods: In this observational, longitudinal, prospective study, best-corrected…
View details →García-Sáenz MR, Castro-Murillo JI, Mercado M et al. · 2026 · Archives of medical research
Introduction Predicting resistance to cabergoline in prolactinomas remains a challenge. While prolactin (PRL)-based ratios help differentiate prolactinomas from non-functioning pituitary adenomas (NFPAs), their role in forecasting…
View details →Aydın Güçlü Ö, Demirdöğen E, Hunutlu FÇ et al. · 2026 · BMC infectious diseases
Background Cytomegalovirus (CMV) infection is an important cause of morbidity and mortality among immunocompromised patients, particularly those with hematologic malignancies. The present study aims to evaluate the clinical features,…
View details →Lee A, Higgins S, O'Driscoll D et al. · 2026 · Journal of autism and developmental disorders
OBJECTIVE: To examine the association between neonatal jaundice requiring hospital treatment and autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in offspring by age 14 years. METHODS: We used data from…
View details →Lan H, Ding Y, Liu M · 2026 · American journal of cancer research
Background Patients with high-risk diffuse large B-cell lymphoma (DLBCL) have poor prognoses, and the comparative efficacy between R-CHOP and R-DA-EPOCH regimens remains controversial. Objective To compare the efficacy and safety of R-CHOP…
View details →Yadav D, Ghuman NK, Kathuria P et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Objective To study the effect of intrauterine instillation of Hyaluronan enriched media on reproductive outcomes of intrauterine insemination treatment. Design and participants 100 couples with unexplained infertility were approached and…
View details →Losiewicz S, Collis B, El-Dalati S et al. · 2026 · Open forum infectious diseases
This single-center retrospective study evaluated 218 patients with injection drug use-associated infective endocarditis, 169 of whom received medications for opioid use disorder (MOUD). Initiation of MOUD was associated with a…
View details →Premkumar A, Arellano E, Heo KY et al. · 2026 · The Journal of arthroplasty
Background The use of short-term postoperative corticosteroid regimens has been reported to improve pain control and decrease opioid consumption following total knee arthroplasty (TKA). The purpose of this study was to evaluate the effect…
View details →Altavilla S, Di Pietro N, Loconsole D et al. · 2026 · Antibiotics (Basel, Switzerland)
Background Carbapenem-resistant Enterobacterales (CRE) require early identification and appropriate patient placement to prevent in-hospital transmission. Bed Management plays a key organizational role in coordinating screening results and…
View details →Zhang Y, Zhao J, Gao Q et al. · 2026 · Virchows Archiv : an international journal of pathology
Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations occur in 25-30% of non-small cell lung cancer (NSCLC) patients. Pooled analyses in previous research have largely focused on the prognostic and predictive value of overall or…
View details →Yan L, Yin H, Shi L et al. · 2026 · Drug design, development and therapy
Purpose To evaluate the efficacy and safety of PHPV in the treatment of persistent high-risk papillomavirus (hrHPV) infection of the cervix. Patients and methods A randomized controlled trial (RCT) was conducted on patients with persistent…
View details →Shi Y, Shen Y, Zhou X et al. · 2026 · European journal of dental education : official journal of the Association for Dental Education in Europe
Objective To evaluate a Bloom's Taxonomy-based occupational exposure (OE) prevention program's impact on dental trainees' competencies compared to conventional training, assessing knowledge, skills, satisfaction, and exposure rates to…
View details →Meirmanova M, Abiltayeva A, Noso Y et al. · 2026 · Georgian medical news
Introduction Uterine fibroids remain one of the most common benign tumors of the female reproductive system and a significant cause of menorrhagia, pain, symptoms of pelvic organ compression, and a reduced quality of life. Due to the…
View details →Furtado R, Weinberg L, Haghighi KS et al. · 2026 · ANZ journal of surgery
Background Postoperative pancreatic fistula (POPF) is the primary cause of morbidity after distal pancreatectomy (DP). This trial investigated the application of a combined polyethylene glycol (PEG) and recombinant human albumin sealant…
View details →Kumar A, Aduri TT, Dhatt SS et al. · 2026 · Journal of clinical orthopaedics and trauma
Background This study evaluated bladder, bowel, and sexual function outcomes following surgical decompression for cauda equina syndrome (CES) using urodynamic studies (UDS) and patient-reported outcome measures (PROMs), and explored the…
View details →Ouazzani S, Lemmers A, Boskoski I et al. · 2026 · Obesity surgery
Background Endoscopic sleeve gastroplasty (ESG) is an established endoscopic bariatric therapy. Two main platforms are currently used in clinical practice: the OverStitch Endoscopic Suturing System (OESS) and the triangulation Endomina…
View details →He M, Wang L, Zhang S et al. · 2026 · Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Purpose To investigate the effect of nightly 0.01% atropine eye drops on choroidal thickness (ChT) in pre-myopic children (at risk of myopia). Methods In a 12-month randomised, double-blind, placebo-controlled trial, 54 children aged 5-12…
View details →Masoud M, El-Assal MA, Ibrahim MA et al. · 2026 · International orthopaedics
Background The peroneus longus tendon (PLT) has emerged as a promising graft option for anterior cruciate ligament reconstruction (ACLR), with acceptable outcomes; however, concerns have been raised about potential donor-site morbidity,…
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