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20,211 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Effect of Vericiguat on Pulmonary Artery Pressures in Patients With Heart Failure: Real-World Insights From Pressure Sensor Monitoring.

Elad B, Lotan D, Richter I et al. · 2026 · Journal of cardiovascular pharmacology

Abstract Vericiguat improves outcomes in heart failure (HF) by promoting vasodilation of the systemic and pulmonary arterial beds. Little is known about its impact on pulmonary artery pressure (PAP). We aimed to study this effect using…

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Negative / Null Result ReportOpen accessMedicine

Effect of an Eight-Week Breathing Exercise Program on the Respiratory Function and Craniovertebral Angle in Dental Students: A Pre-test and Post-test Quasi-experimental Study.

Hafez E, Ashraf E, Saeed S et al. · 2026 · Cureus

Introduction Dental training requires prolonged static and forward-leaning working positions that may contribute to forward head posture. Forward head posture can be quantified using the craniovertebral angle (CVA) and may be associated…

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Negative / Null Result ReportOpen accessMedicine

Acute effects of continuous and interval cycling on salivary SIgA and anti-microbial peptide secretions: a randomized crossover trial.

Ito R, Uchida M, Fujie S et al. · 2026 · European journal of applied physiology

Purpose This study aimed to examine the acute effects of continuous and interval cycling on salivary secretory immunoglobulin A (SIgA) and anti-microbial peptides. Methods In a randomized crossover trial, 12 healthy young untrained men (22…

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Negative / Null Result ReportMedicine

Lanthanum carbonate lowers serum phosphorus without altering body phosphorus burden in maintenance peritoneal dialysis patients: a randomized crossover trial.

Kopple JD, Bross R, Ekramzadeh M et al. · 2025 · The American journal of clinical nutrition

Background Many studies show that intestinal phosphate binders reduce serum phosphorus concentrations in hyperphosphatemic patients with chronic kidney failure. To our knowledge, there are virtually no studies of the effect of these…

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Negative / Null Result ReportMedicine

Prospective Monitoring of Serum Values of CBC, Total IgE, Thyroid Findings, D-Dimer, Vitamin D, and Inflammatory Molecules CRP, ESR, and IL-6 and Clinical Features of Chronic Spontaneous Urticaria Patients During Antihistamine Treatment.

Kuna M, Štefanović M, Barac E et al. · 2026 · International journal of molecular sciences

Having appropriate and meaningful diagnostic procedures is crucial in the approach to patients with chronic spontaneous urticaria (CSU), so we wanted to investigate relationships between CSU patients' common serum factors and clinical CSU…

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Negative / Null Result ReportOpen accessMedicine

Analysis of PR-1, PR-2, PR-10, chitinases and chitinase-like proteins genes expression in pea roots under the action of salicylic acid and methyl jasmonate.

Egorova AM · 2026 · Vavilovskii zhurnal genetiki i selektsii

Stress phytohormones - salicylic and jasmonic acids - participate in the plant defense response. The increase in the content of these compounds during plant infection by pathogens leads to the activation of signaling pathways, ultimately…

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Negative / Null Result ReportMedicine

Advances in Marfan Syndrome Care: The Limits of Type B Dissection.

Tchitchinadze M, Milleron O, Eliahou L et al. · 2026 · The Annals of thoracic surgery

Background To evaluate the progress of care for patients with Marfan syndrome with FBN1 pathogenic variant carriers over the past 30 years. Methods Patients who visited the center were entered into a prospective registry. Aortic events…

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Negative / Null Result ReportMedicine

Return to Driving After Anterior Total Hip Arthroplasty.

Masturov YA, Hogan WB, Regal S et al. · 2026 · Orthopedics

Background Traditional guidance after posterior-approach total hip arthroplasty (THA) recommends return to driving at 6-8 weeks. Muscle-sparing direct anterior THA (A-THA) may enable earlier recovery. Our objective was to assess brake…

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Negative / Null Result ReportMedicine

Structure of sulfur chains encapsulated in single-walled carbon nanotubes.

Saiful Islam M, Fujimori T, Miyanaga T et al. · 2025 · Journal of physics. Condensed matter : an Institute of Physics journal

The encapsulation of sulfur (S) within single-walled carbon nanotubes (S@SWCNTs) provides a unique opportunity to stabilize and study the structure and bonding of one-dimensional sulfur chains, which do not exist in a free state. In this…

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Negative / Null Result ReportMedicine

Evaluation of skeletal muscle indicators following allogeneic hematopoietic stem cell transplantation: verification of skeletal muscle mass adjustment.

Hamada R, Tamaki A, Murao M et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Purpose Bioelectrical impedance analysis (BIA) has emerged as a simple, noninvasive method for evaluating skeletal muscle. However, BIA is sensitive to fluctuations in body water and can overestimate skeletal muscle mass, which may obscure…

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Negative / Null Result ReportMedicine

Adding free leucine to a balanced essential amino acid mixture suppresses intracellular transamination of isoleucine and valine in healthy older adults.

Knezek SB, Engelen MPKJ, Coyle KS et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)

Background Adding leucine (LEU) to protein meals enhances protein anabolism, but excess LEU reduces valine (VAL) and isoleucine (ILE) plasma concentrations. We examined in older adults whether additional LEU added to an essential amino…

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Negative / Null Result ReportMedicine

Zinc deficiency is associated with erythropoietin-stimulating agents hyporesponsive anemia in peritoneal dialysis patients: a cross-sectional study.

Kuwahara F, Harada K, Nagata M et al. · 2026 · Clinical and experimental nephrology

Background Zinc deficiency is widely recognized as a cause of anemia, but no studies have clarified the impact of zinc deficiency on achieving target hemoglobin levels in patients undergoing peritoneal dialysis (PD) and receiving high-dose…

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Negative / Null Result ReportMedicine

Risk factors for asseptic loosening after revision total knee replacement (rTKR): a component-specific analysis of femoral and tibial reconstruction.

Souto CS, Pereira F, Carvalho A et al. · 2026 · The Knee

Background Revision total knee arthroplasty (rTKA) remains a technically demanding procedure, with re-revision representing a major clinical challenge. The role of reconstruction strategies, particularly the use of augments and metaphyseal…

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Negative / Null Result ReportMedicine

Similar Outcomes in Proximal Humerus Fractures Treated With Conventus Intramedullary Cage Device and Open Reduction Internal Fixation.

Kurkowski SC, Taleghani ER, McMillan P et al. · 2026 · Journal of orthopaedic trauma

Objectives To compare clinical outcomes between open reduction and internal fixation (ORIF) with or without Conventus intramedullary cage (CC) for proximal humerus fractures. Methods Design Retrospective cohort study. Setting Level 1…

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Negative / Null Result ReportMedicine

A comparative experimental study on the impact of radiotherapy dose rate and melatonin pretreatment in tongue and esophageal tissues.

Hacımustafaoğlu F, Aras S, Çaykara Peran B et al. · 2026 · International journal of radiation biology

Aim This study aimed to investigate the differential biological responses in tongue and esophageal tissues induced by flattening filter (FF) and flattening filter-free (FFF) beams at varying dose rates, and to assess the radioprotective…

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Negative / Null Result ReportMedicine

Contralateral vs. ipsilateral hemilaminectomy for spinal meningiomas: impact on resection completeness, stability, and recurrence.

Yavuz AY, Can F, Avci İ et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Aim Spinal meningiomas (SMs) account for approximately 25-40% of intradural extramedullary spinal tumors [1]. The classical symptomatology typically begins with pain, followed by motor and/or sensory deficits, gait disturbances, and…

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Negative / Null Result ReportMedicine

Data-Driven Discovery of Plant-Based Dietary Subtypes and Their Association with Cancer, Cardiovascular diseases, and Type 2 diabetes in Postmenopausal Women: Insights from the Women's Health Initiative.

Moosavi D, Nejati N, Arcan C et al. · 2026 · Journal of the Academy of Nutrition and Dietetics

Background Plant-based diets have been associated with lower risks of chronic diseases; however, not all plant-based diets confer equal health benefits. Data-driven methods provide an opportunity to empirically identify distinct…

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Negative / Null Result ReportMedicine

Early outcomes of facilitated transfemoral versus alternative access for transcatheter aortic valve replacement in patients with peripheral arterial disease.

Mustafa A, Wang D, Dutton C et al. · 2026 · The Journal of invasive cardiology

Objectives Transfemoral (TF) access for transcatheter aortic valve replacement (TAVR) may be challenging in patients with peripheral arterial disease (PAD). Alternative access through intra- and extrathoracic approaches can be performed.…

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