e-ISSN: Pending

Browse the failure-mode index

20,211 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Screening check test to confirm the relative reactivity and applicability of 2,4-dinitrophenylhydrazine impregnated-filters for formaldehyde on other compounds

Naoko Inoue, Mitsutoshi Takaya · 2022 · Journal of Occupational Health

Abstract Objectives A simple check test method was designed to confirm whether a 2,4-dinitrophenylhydrazine (DNPH) filter for formaldehyde can be used to measure other compounds. Methods Sample mixtures containing the same concentrations…

View details →
Negative / Null Result Report

EFEKTIVITAS PUSAT INFORMASI KONSELING REMAJA (PIK-R); STUDI KUALITATIF DENGAN TEKNIK MOST SIGNIFICANT CHANGE (MSC)

Yoga Tri Nugroho, Rumita Ena Sari, Arnild Augina Meckarische · 2021 · JURNAL ILMU DAN TEKNOLOGI KESEHATAN TERPADU

This study aimed to describe the most significant change stories in the indicators of the effectiveness of the Adolescent Counseling Information Center (PIK-R) at SMA Negeri 4 Kota Jambi. This research was qualitative study with a…

View details →
Negative / Null Result Report

Molecular Diagnostic Techniques Used to Confirm an Unusual Case of BAPoma

Aaron Atkinson, Konstantinos Linos, Shaofeng Yan et al. · 2017 · The FASEB Journal

Study Objective BAP1 (BRCA1‐associated protein 1) is a critical tumor suppressor that promotes genome stability and DNA damage response, in addition to other cellular processes. BAP1 maps to 3p21 and is a nuclear localized deubiquitinating…

View details →
Negative / Null Result Report

#4204 MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING BIOMARKERS OUTPERFORM LAB BIOMARKERS FOR PREDICTING PROGRESSION OF DIABETIC KIDNEY DISEASE

Paul Hockings, Kianoush Makvandi, Johannes Hulthe et al. · 2023 · Nephrology Dialysis Transplantation

Abstract Background and Aims We recently showed that comprehensive non-contrast multiparametric Magnetic Resonance Imaging (mpMRI) allowed functional and structural assessment of diabetic kidney disease (DKD) and that an imaging endpoint,…

View details →
Negative / Null Result Report

“Simple mechanical devices did not improve pelvis positioning in AP pelvis radiographs for reliable assessment of the acetabular orientation”

Matthias Brockmeyer, Sebastian Lott, Jonas Stroeder et al. · 2019 · Journal of Experimental Orthopaedics

Abstract Background The aim of this study was to develop two simple positioning devices for anteroposterior pelvis radiographs and to evaluate their effect on accuracy of the radiographs for assessment of the acetabular orientation…

View details →
Negative / Null Result Report

No significant projected climate change effects on the geographic ranges of marine aquaculture species under the sustainable scenario (SSP 1-1.9, 1.5°C warming)

Amy Leigh Mackintosh, Griffin Goldstein Hill, Mark John Costello et al. · 2025 · npj Ocean Sustainability

Abstract Aquaculture is increasingly relied upon for global seafood production, projected to be the leading supplier by 2030. Climate change impacts on species health and industry productivity are already evident, creating uncertainties…

View details →
Negative / Null Result Report

Detection of clinically significant prostate cancer by micro-ultrasound-informed systematic biopsy during MRI/micro-ultrasound fusion biopsy

Betty Wang, Stacey Broomfield, Anaïs Medina Martín et al. · 2022 · Canadian Urological Association Journal

Introduction: High-resolution micro-ultrasound (microUS) is a novel imaging technique that may visualize clinically significant prostate cancer (csPCa), including those missed by magnetic resonance imaging (MRI), in real-time during…

View details →
Negative / Null Result Report

Study: The Lack of Significant Association of the Catechol‐ O ‐Methyl Transferase (COMT) Gene Polymorphism in Violent Offenders with Mental Retardation

Aysun Baransel Isir, Alper Ibrahim Dai, Muradiye Nacak et al. · 2010 · Journal of Forensic Sciences

Abstract: Little is known about criminality of cognitively impaired people and also there have been no reports on the relationship between catechol‐ O ‐methyl transferase (COMT) and committed Mental Retardation (MR) subjects. In the…

View details →
Negative / Null Result Report

Abstract 191: Alcohol Consumption Before Injury Did Not Improve Neurological Outcomes In Patients With Severe Traumatic Brain Injury: A Nationwide, Retrospective Cohort Study

Tsuyoshi Nojima, Hiromichi Naito, Takashi Hongo et al. · 2022 · Circulation

Introduction: Traumatic brain injury (TBI) is a major global public health concern. Notably, alcohol may confer neuroprotective effects by inhibiting of N-methyl-D-aspartate receptors; however, the impact of alcohol exposure before injury…

View details →
Negative / Null Result Report

Did Aristotle have a Doctrine of Existential Import?

Byeong-uk Yi · 2025 · Open Philosophy

Abstract Modern logicians hold that traditional logic makes a serious error by accepting the subalternation thesis , the thesis that universal affirmatives imply matching particular affirmatives. But some traditional logicians (e.g.,…

View details →
Negative / Null Result Report

Vascular Stiffness, Instead of Coronary Artery Calcification, Exhibits Significant Association With Hypertension Risk in General Population

Chia-Ter Chao, Min-Tser Liao, Chung-Kuan Wu · 2025 · American Journal of Hypertension

Abstract BACKGROUND Hypertension (HTN) significantly increases cardiovascular risk worldwide, and its incidence is expected to rise further over time. Both coronary artery calcification (CAC) and vascular stiffness (VS) potentially…

View details →
Negative / Null Result Report

School leadership and organizational change: does teacher innovative behaviour play a significant role?

Grace Damptey Manu, Michael Osei Aboagye, Seth Yeboah Ntim et al. · 2025 · International Journal of Educational Management

Purpose The implementation of school improvement initiatives – such as Ghana’s standards-based curriculum (SBC) – necessitates transformational and contextually responsive school leadership. In line with this, the recent primary school…

View details →
Negative / Null Result Report

Why did Endurance sink?

Jukka Tuhkuri · 2025 · Polar Record

Abstract Sir Ernest Shackleton’s ship, Endurance , was crushed by Antarctic sea ice and sank in November 1915. Since then, it has been widely considered that Endurance was the strongest polar ship of its time and was lost because ice tore…

View details →
Negative / Null Result Report

Outcome of Second Line Treatment in Patients with Chronic Lymphocytic Leukemia Did Not Improve 2002-2013: A Population-Based Study from a Well-Defined Geographic Region

Anna Asklid, Agnes Mattsson, Einar Björgvinsson et al. · 2015 · Blood

Abstract Background: Treatment of relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) remains challenging. Major progress has been achieved with new agents such as ibrutinib and idelalisib. However relapses still occur with…

View details →
Negative / Null Result Report

Whom did the karasuk people resemble?

A. G Kozintsev · 2023 · Etnograficheskoe obozrenie

To test Yuri Rychkov’s claim that the physical type of the Karasuk people was identical to that of the highlanders of Western Pamir, 24 male Karasuk cranial samples were subjected to a multivariate comparison with 59 samples representing…

View details →
Negative / Null Result ReportOpen accessMathematics

Forecasting Multivariate Time Series under Predictive Heterogeneity: A Validation-Driven Clustering Framework

Ziling Ma, Ángel López Oriona, Hernando Ombao et al. · 2026 · arXiv

We study adaptive pooling under predictive heterogeneity in high-dimensional multivariate time series forecasting, where global models improve statistical efficiency but may fail to capture heterogeneous predictive structure, while naive specialization can induce negative transfer. We formulate adaptive pooling as a statistical decision problem and propose a validation-driven framework that determines when and how specialization should be applied. Rather than grouping series based on representation similarity, we define partitions through out-of-sample predictive performance, thereby aligning

View details →