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19,820 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Efficacy of Nurse-Led WIKAP Intervention on Hypoglycemia Coping Confidence and Outcomes in Adolescents with Type 1 Diabetes Mellitus: A Quasi-Experimental Study in Zhijiang, China.

Xiao, Zheng, Guo et al. · 2026 · Patient preference and adherence

Hypoglycemia is a frequent and burdensome complication in adolescents with type 1 diabetes mellitus (T1DM). Despite its high prevalence, structured interventions targeting hypoglycemia coping confidence remain scarce, especially in China.…

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Negative / Null Result ReportMedicine

The effectiveness of a cognitive behavioural therapy for insomnia based intervention to improve sleep quality in nursing home residents, a cluster randomised controlled trial.

Lahaye, Haegdorens, Franck et al. · 2026 · European geriatric medicine

To evaluate the effectiveness of a structured, team-delivered intervention based on cognitive behavioural therapy for insomnia (CBT-I) on sleep and related outcomes in nursing home residents. A cluster randomised controlled trial with…

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Negative / Null Result ReportMedicine

Occurrence of acrylamide and 4-methylimidazole in roasted and ground coffee and the effect of L-asparaginase treatment of green coffee on their levels.

da Costa, Ramirez, de Carvalho et al. · 2026 · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment

Acrylamide and 4-methylimidazole (4-MEI) are heat-induced contaminants formed during coffee roasting, raising concerns due to their potential toxicological effects. Considering the limited information about the occurrence of these…

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Negative / Null Result ReportMedicine

The cortisol awakening response (CAR) of elite athletes is elevated before a competition, but no interaction with sport type.

Jiménez, Lopez-Lluch, Barón-López et al. · 2026 · Psychoneuroendocrinology

The cortisol awakening response (CAR) is thought to represent an anticipatory mechanism to prepare for upcoming demands. In sport, competition increases in the CAR have been reported, although findings remain inconsistent. A study on…

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Negative / Null Result ReportMedicine

Exploring an integrated group psychotherapy-exercise program for multiple sclerosis: a non-randomized pilot study.

Abelovska, Malinova, Sucha et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

This pilot study evaluated "Your Health Belongs to You," a six-week group intervention combining psychotherapy and exercise to improve quality of life, emotional health, and symptom management in individuals with Multiple Sclerosis (MS),…

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Negative / Null Result ReportMedicine

Effects, Acceptability, and Use of a Dynamically Tailored Mobile What Do You Drink Intervention to Reduce Excessive Drinking Among Adolescents and Young Adults in the Netherlands: Randomized Controlled Trial.

van Keulen, Voogt, Kleinjan et al. · 2026 · JMIR mHealth and uHealth

Excessive alcohol consumption among adolescents and young adults is a serious health problem. Dynamically tailored interventions could reduce their excessive drinking. We therefore developed "What Do You Drink" (WDYD), a 17-week…

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Negative / Null Result ReportMedicine

Comparison of Submental Muscle Activation and Tongue Pressure of Tongue Hold, Effortful Swallow and Mendelsohn Maneuvers in Different Gravitational Positions.

Cengiz, Yıldırım, Yaşaroğlu et al. · 2026 · Dysphagia

This study aimed to investigate the effects of Tongue Hold Maneuver (THM), Mendelsohn Maneuver (MM), and Effortful Swallow Maneuver (ESM) performed under different gravitational positions (90° sitting, 45° sitting, supine, and…

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Negative / Null Result ReportMedicine

Improving ricotta cheese shelf life using saffron petal extract double nanoemulsions stabilized by plant proteins and Lepidium sativum L. gum.

Bakhshalipoor, Bolandi, Nahidi et al. · 2026 · Scientific reports

This study evaluated the effects of double nanoemulsions of saffron petal extract (DN-SPE), stabilized with soybean (SPI) and pea protein isolates (PPI), alone or combined with Lepidium sativum L. seed gum (LSG) (SL or PL), on the quality…

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Negative / Null Result ReportMedicine

Cholinesterase activity determines the action potential-dependent increase in glycine receptor-mediated inhibitory synaptic transmission in the substantia gelatinosa of the spinal trigeminal nucleus of the rat.

Kawamura, Masaki, Kato · 2026 · Journal of pharmacological sciences

Acetylcholine-mediated modulation of pain-associated behaviors has been progressively well described. The mechanisms of cholinergic antinociception have been reported to involve the activation of nAChRs or mAChRs modulating GABAergic…

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Negative / Null Result ReportMedicine

The impact of universal credit on mental, physical, and financial well-being: longitudinal evidence from the UK household longitudinal survey.

Bai, Kim, Cao et al. · 2026 · Social psychiatry and psychiatric epidemiology

Universal Credit (UC) is a major UK welfare reform that consolidates six means-tested benefits into a single monthly payment, aiming to simplify benefits delivery and incentivize labor market participation. However, concerns have emerged…

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Negative / Null Result ReportMedicine

Comparative bio-efficacy and molecular insights of North-Western Himalayan conifers, Cedrus deodara and Juniperus macropoda essential oils against two storage insect pests.

Guleria, Horijan, Kumar et al. · 2026 · Scientific reports

The study aimed to evaluate fumigation and repellent properties of essential oils (EOs) from Juniperus macropoda leaves and cedarwood, Cedrus deodara against storage pests viz., Tribolium castaneum and Callosobruchus maculatus. Further,…

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Negative / Null Result ReportMedicine

Age-Related Hearing Loss and Cognition: The Role of Bilingualism.

Heidari, Amiri, Mobarakeh · 2026 · Journal of speech, language, and hearing research : JSLHR

Age-related hearing loss (ARHL) has been associated with cognitive decline. Although bilingualism may influence cognitive performance, its interaction with hearing loss remains unclear. This study aimed to investigate the effects of ARHL…

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Negative / Null Result ReportMedicine

Retrospective Propensity-Matched Comparison of Noninvasive Positive Pressure Ventilation Versus High-Flow Nasal Cannula on Reintubation Rates in Neurosurgical Intensive Care Patients.

Wang, Lv, Zeng et al. · 2026 · Neurocritical care

This study compared the effectiveness of noninvasive positive pressure ventilation (NIPPV) and high-flow nasal cannula (HFNC) in preventing reintubation among neurosurgical intensive care patients following extubation. A retrospective…

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