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Browse the failure-mode index

20,211 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Significant difference in gut microbiota Bifidobacterium species but not Lactobacillus species in colorectal cancer patients in comparison with healthy volunteers using quantitative real-time PCR

Fahime Esfandiari, Bita Bakhshi, Tayebe Shahbazi et al. · 2024 · PLOS ONE

Background Colorectal cancer (CRC), with a growing incidence trend, is one of the most diagnosed cancers and the second cause of cancer-related deaths worldwide. The literature has frequently focused attention on the correlation between…

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Negative / Null Result Report

Social role effects on English particle verb variation fail to replicate

Naomi Lee, Laurel Mackenzie · 2023 · Canadian Journal of Linguistics/Revue canadienne de linguistique

Abstract The English particle verb alternation has been argued to be sensitive to the social role occupied by speakers on radio broadcasts; Kroch and Small (1978) argue that radio show hosts and in-studio guests’ greater sensitivity to…

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Negative / Null Result Report

Nocturnal Emissions: A Failure to Replicate

Keith F. Widaman, Jonathan L. Helm · 2012 · The American Journal of Psychology

Abstract A time series of nocturnal emissions was presented in The American Journal of Psychology in 1904. The anonymous author of this remarkable article provided the time series to support his contention that his nocturnal emissions…

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Negative / Null Result Report

Why Halley Did Not Discover Proper Motion and Why Cassini Did

Frank Verbunt, Marc van der Sluys · 2019 · Journal for the History of Astronomy

In 1717, Halley compared contemporaneous measurements of the latitudes of four stars with earlier measurements by ancient Greek astronomers and by Brahe, and from the differences concluded that these four stars showed proper motion. An…

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Negative / Null Result Report

Significant difference in Miscanthus species root carbon exudation rate

Amanda J Holder, Rebecca Wilson, Karen Askew et al. · 2025 · Annals of Botany

Abstract Background and Aims The cultivation of Miscanthus, a giant perennial grass and promising biomass crop, is expected to increase globally in response to climate mitigation policies and sustainable agriculture goals. Little is known…

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Negative / Null Result Report

Mean resolvent operator of a statistically steady flow

Colin Leclercq, Denis Sipp · 2023 · Journal of Fluid Mechanics

This paper introduces a new operator relevant to input–output analysis of flows in a statistically steady regime far from the steady base flow: the mean resolvent ${{\boldsymbol{\mathsf{R}}}}_0$ . It is defined as the operator predicting,…

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Negative / Null Result Report

What do we know about ‘rape myth’ research and the claim that there is ‘overwhelming evidence’ that juries are prejudiced in rape trials?

Stuart Waiton · 2023 · The International Journal of Evidence & Proof

This paper examines the research by Fiona Leverick and demonstrates the methodological flaws in much of the ‘rape myth’ and mock jury research. Other ideas about rape myths and the ‘justice gap’ are explored and seen to be questionable.…

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Negative / Null Result Report

Superficial parasternal intercostal plane blocks with liposomal bupivacaine did not significantly reduce opioid use after cardiac surgery: a randomized clinical trial

Eric R Simon, Alysan Mallery, John Silva et al. · 2025 · Regional Anesthesia & Pain Medicine

Background Acute pain after cardiac surgery via median sternotomy is commonly managed with multimodal analgesia, but optimal regional techniques remain uncertain. Superficial parasternal intercostal plane (SPIP) blocks have shown promise…

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Negative / Null Result Report

Liquid fermented cereals with added Pediococcus acidilactici did not reduce post-weaning diarrhea in pigs – an Escherichia coli challenge study

Jiajia Xu, Samantha Joan Noel, Charlotte Lauridsen et al. · 2023 · Frontiers in Veterinary Science

The effect of feeding fermented liquid feed (FLF) with added Pediococcus acidilactici to weaning piglets challenged with enterotoxigenic Escherichia coli (ETEC) F4 on aspects of diarrhea, performance, immune responses, and intestinal…

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Negative / Null Result Report

Partial trailside Japanese barberry (Ranunculales: Berberidaceae) removal did not reduce the abundance of questing blacklegged ticks (Acari: Ixodidae)

Susan P Elias, Peter W Rand, Charles B Lubelczyk et al. · 2024 · Environmental Entomology

Abstract In a nature reserve in southern Maine, we removed invasive Japanese barberry (Berberis thunbergii de Candolle) along sections of forested recreational trails that ran through dense barberry infestations. Barberry thickets provide…

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Negative / Null Result Report

What do general adult psychiatry patients think we should call borderline personality disorder? A cross-sectional study to find the most acceptable diagnostic term

David Hayward, Amy Fourie, Donald MacIntyre et al. · 2025 · BJPsych Bulletin

Aims and method To determine the most acceptable term for borderline personality disorder (BPD). We conducted a cross-sectional study of patients who know what it feels like to be diagnosed with a mental disorder. The main outcome measures…

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Negative / Null Result Report

Did the Hospital Readmissions Reduction Program Reduce Readmissions without Hurting Patient Outcomes at High Dual-Proportion Hospitals Prior to Stratification?

Zhiyou Yang, Peter Huckfeldt, Jose J. Escarce et al. · 2022 · INQUIRY: The Journal of Health Care Organization, Provision, and Financing

Since the implementation of Medicare’s Hospital Readmissions Reduction Program (HRRP), safety-net hospitals have received a disproportionate share of financial penalties for excess readmissions, raising concerns about the fairness of the…

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