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Browse the failure-mode index

20,211 real negative results, null findings, and replication failures · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Failed supernova remnants

Daichi Tsuna · 2021 · Publications of the Astronomical Society of Japan

Abstract In a failed supernova, partial ejection of the progenitor’s outer envelope can occur due to weakening of the core’s gravity by neutrino emission in the protoneutron star phase. We consider emission when this ejecta sweeps up the…

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Negative / Null Result Report

Significant hot hand effect in the game of cricket

Sumit Kumar Ram, Shyam Nandan, Didier Sornette · 2022 · Scientific Reports

Abstract We investigate the predictability and persistence of individual and team performance (hot-hand effect) by analyzing the complete recorded history of international cricket. We introduce an original temporal representation of…

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Negative / Null Result Report

Significant effect of compositional grading on SAGD performance in a fractured carbonate heavy oil reservoir

Hossein Ghalenavi, Saeid Norouzi-Apourvari, Mahin Schaffie et al. · 2019 · Journal of Petroleum Exploration and Production Technology

Abstract In reservoir simulation, the fluid composition is usually assumed uniform for the whole reservoir, while in many reservoirs, oil and gas composition changes with depth. This phenomenon which is known as compositional grading could…

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Negative / Null Result Report

A single residue substitution accounts for the significant difference in thermostability between two isoforms of human cytosolic creatine kinase

Huihui Liu, Yan-Song Gao, Xiang-Jun Chen et al. · 2016 · Scientific Reports

Abstract Creatine kinase (CK) helps maintain homeostasis of intracellular ATP level by catalyzing the reversible phosphotransfer between ATP and phosphocreatine. In humans, there are two cytosolic CK isoforms, the muscle-type (M) and the…

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Negative / Null Result Report

Changes in caregiver depression, anxiety, and satisfaction with family relationships in families of children who did and did not undergo resective epilepsy surgery

Natalie L. Phillips, Elysa Widjaja, Mary Lou Smith · 2020 · Epilepsia

Abstract Objective To evaluate longitudinal changes in caregiver depression, anxiety, and family relationships following resective surgery for pediatric drug‐resistant epilepsy (DRE). Methods This multicenter cohort study involved 177…

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Negative / Null Result Report

Preventative effects of antioxidants on changes in sebocytes, outer root sheath cells, and Cutibacterium acnes -pretreated mice by particulate matter: No significant difference among antioxidants

Mi Hee Kwack, Dae-Lyong Ha, Weon Ju Lee · 2022 · International Journal of Immunopathology and Pharmacology

Objectives Particulate matter (PM) is an air pollutant that can damage human skin; antioxidants have shown some efficacy in alleviating PM-induced skin inflammation. We investigated the antioxidant effects of punicalagin,…

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Negative / Null Result Report

Insights into protection against Mycobacterium tuberculosis infection: time to officially confirm another phenotype?

Todia P. Setiabudiawan, Philip C. Hill, Andrew R. DiNardo et al. · 2025 · Journal of Clinical Investigation

Immune correlates of protection against infection with Mycobacterium tuberculosis (Mtb) remain elusive. In this issue of the JCI , Dallmann-Sauer and authors demonstrate that lack of tuberculin skin test (TST) and interferon γ release…

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Negative / Null Result Report

Patient-defined outcomes for pain, fatigue, emotional distress, and interference with activities did not differ by age for individuals with musculoskeletal pain

Abigail T. Wilson, Steven Z. George, Joel E. Bialosky · 2019 · PAIN Reports

Abstract Introduction: Age impacts the prevalence and experience of musculoskeletal pain; however, it is unknown whether this factor impacts patient's anticipated outcomes after treatment. Objective: Using the Patient-Centered Outcomes…

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Negative / Null Result Report

When and how do innovation ecosystems outperform integrated organizations? On technological interdependencies and ecosystem performance

Huanren Zhang, Yimei Hu, Xianwei Shi et al. · 2022 · Industrial Management & Data Systems

Purpose Studies have documented the distinctive advantage of innovation ecosystems in integrating and recombining heterogeneous knowledge resources across firms' boundaries. However, hierarchical governance in the form of vertical…

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Negative / Null Result Report

Evaluating individual‐ and sample‐level response to treatment for inpatients with eating disorders: Is change clinically significant?

Colleen C. Schreyer, Allisyn Pletch, Irina A. Vanzhula et al. · 2022 · International Journal of Eating Disorders

Abstract Objective Evaluating treatment efficacy solely on whether sample‐level change is statistically significant does not indicate whether clinically significant change (CSC) has occurred at the individual‐level. We assessed whether…

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Negative / Null Result Report

Challenging the understanding of significant improvement and outcome in schizophrenia – the concept of reliable and clinically significant change methods

Rebecca Schennach, Hans‐Jürgen Möller, Michael Obermeier et al. · 2015 · International Journal of Methods in Psychiatric Research

Abstract Significant changes of schizophrenia patients during inpatient treatment were evalutaed and compared to established outcome criteria. The concept of reliable and clinically significant change methods was applied to three hundred…

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Negative / Null Result Report

“I had to change my attitude”: narratives of most significant change explore the experience of universal home visits to pregnant women and their spouses in Bauchi State, Nigeria

Loubna Belaid, Umaira Ansari, Khalid Omer et al. · 2021 · Archives of Public Health

Abstract Background Universal home visits to pregnant women and their spouses in Bauchi State, northern Nigeria, discussed local evidence about maternal and child health risks actionable by households. The expected results chain for…

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Negative / Null Result Report

Evaluating the Impact of the Medical Education Partnership Initiative at the University of Zimbabwe College of Health Sciences Using the Most Significant Change Technique

Susan C. Connors, Shemiah Nyaude, Amelia Challender et al. · 2017 · Academic Medicine

Problem In medical education, evaluating outcomes from programs intended to transform attitudes or influence career trajectories using conventional methods of monitoring is often difficult. To address this problem, the authors adapted the…

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Negative / Null Result Report

Enhanced Depth Imaging Optical Coherence Tomography Technology Reveals a Significant Association Between Optic Nerve Drusen Anterior Displacement and Retinal Nerve Fiber Layer Thinning Over Time

Sara Ortiz-Toquero, Francisco J. Muñoz-Negrete, Gema Rebolleda · 2020 · Journal of Neuro-Ophthalmology

Background: Optic disc drusen (ODD) are a dynamic phenomenon, and their appearance, size, and relative location may change. The purpose of this study is to evaluate and quantify the longitudinal changes of buried ODD with enhanced depth…

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Negative / Null Result Report

Partial replacement of soybean meal with full-fat black soldier fly larvae meal in plant-based nursery diets did not influence fecal Escherichia coli colony forming units or improve fecal consistency when pigs were weaned into non-disinfected pens

B Christensen, C Zhu, M Niazy et al. · 2023 · Translational Animal Science

Abstract At weaning, one hundred pigs (21 d of age; 6.96 ± 0.23 kg BW) were used to determine the effect of partially replacing soybean meal (SBM) in corn- and SBM-based nursery diets on growth performance, fecal scores, Escherichia coli…

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