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WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
John M. Carey, Brian J. Fogarty, Marília Gehrke et al. · 2025 · Science Advances
We investigate how to counter misinformation about voter and election fraud using data from the US and Brazil. Our study first compares two types of messages countering claims of widespread fraud: (i) retrospective corrections from…
View details →Davide Faccialà, M. Bonanomi, Bruno Nunes Cabral Tenorio et al. · 2025 · Journal of the American Chemical Society
High Resolution Image Download MS PowerPoint Slide We report a study of the electronic and nuclear relaxation dynamics of the photoexcited RNA base uracil in the gas phase using time-resolved core-level photoelectron spectroscopy together with high-level calculations. The dynamics was investigated by trajectory surface hopping calculations, and the core ionization energies were calculated for geometries sampled from these. The molecule was excited by a UV laser and dynamics probed on the oxygen, nitrogen, and carbon sites by core electron spectroscopy. We find that the main de-excitation chann
View details →Jonas Schmidinger, Viacheslav Barkov, Sebastian Vogel et al. · 2025 · Computers and Electronics in Agriculture
Machine learning and geostatistics are two fundamentally different frameworks for the prediction and spatial mapping of soil properties. Geostatistics leverages the spatial structure of soil properties, whereas machine learning models capture the relationship between available environmental features and soil properties. We propose a hybrid framework that augments machine learning with spatial context through the engineering of ‘spatial lag’ features derived from ordinary kriging. We call this approach ‘kriging prior regression’ (KpR), as it reverses the logic of regression kriging by incorpera
View details →Daniel R. Richardson, Ying Wang, Marie Anne Flannery et al. · 2026 · JAMA Oncology
Importance: Health care systems should strive to achieve outcomes that matter to patients. Limited data exist on the outcomes achieved by patients with cancer with different treatment outcome preferences. Objective: To describe treatment…
View details →Sabine Willems, Vasily Morozov, Julian A. Marschner et al. · 2025 · Journal of Medicinal Chemistry
The ligand-activated transcription factors of the NR4A family are implicated as promising drug targets with neuroprotective and anticancer potential and attract strong attention in drug discovery. Several NR4A modulators have been…
View details →Qi Sun, Yanping Zhao, Simiao Qiao et al. · 2026 · Nature Communications
Radiotherapy can both activate and suppress immunity, making it difficult to predict or modulate these opposing effects for better cancer treatment. Boron neutron capture therapy (BNCT), a cellular-level radiotherapy, has demonstrated…
View details →Matt Lowe, Madeline McKelway · 2026 · Journal of the European Economic Association
Abstract Joint household decision-making becomes more common as economies develop. Can external intervention advance this transition? We study this question in the context of female employment in India. We randomized which spouse was given…
View details →Fulai Zhou, Guangmao Mu, Honglei Bi et al. · 2025 · Cancers
Background. The dense hyaluronan (HA)-rich stroma in solid tumors can prevent effective tumor growth inhibition by hindering drug delivery and immune cell infiltration. However, the degradation of HA alone by systemic delivery of hyaluronidase has not shown significant improvement of tumor growth inhibition. Objectives/Methods. In this study, we targeted hyaluronan degradation by using antibody–enzyme (AbEn) molecules by fusing antibodies to a recombinant human hyaluronidase (HYAL). Results. The AbEn molecules were stable, retained both antigen-binding and enzymatic activities, and demonstrate
View details →Muhammad Murad, Muhammad Ahmed, Nizam ul din et al. · 2026 · AgriEngineering
Artificial intelligence (AI) shows great promise for transforming the agriculture sector and can enable the development of many modern farming practices over conventional methods. Nowadays, AI agents and agentic AI have attained popularity due to their autonomous structure and working mechanism. This research work proposes an agentic AI framework that integrates multiple agents developed for farming land to promote climate-smart agriculture and support United Nations (UN) sustainable development goals (SDGs). The developed structure has four agents: Agent A for monitoring soil properties, Agen
View details →Elliott J. Jenkins, Joseph A. Killick, Owain Zerilli et al. · 2025 · The Journal of Physiology
Abstract Long‐term heat acclimation has been shown to elevate haemoglobin mass (Hb mass ) and enhance maximal oxygen consumption (). To date, however, all evidence derives from exercise‐induced heat stress, making it unclear whether passive strategies, which allow athletes to maintain training intensities, can produce similar adaptations. Moreover, while heat‐induced increases in are often attributed to haematological changes, adaptation of other convective components of oxygen transport may underpin these improvements. To investigate whether 5 weeks of hot‐water immersion (HWI) would enhance
View details →Bin Liu, Changfeng Yan, Ming Lv et al. · 2026 · Computers in Industry
Domain adaptation-based methods are extensively applied to predict the Remaining Useful Life (RUL) of rolling bearings under complex operating conditions. However, the nonlinear degradation process of bearings gives rise to markedly…
View details →Chen Ding, Dize Li, Linzhu Su et al. · 2026 · International Journal of Oral Science
Nanotechnology has provided thousands of novel nano-antimicrobials possessing features uncommon in clinically available antimicrobials. Here, nanocarriers loaded with conventional antimicrobials and responding to environmental changes upon…
View details →Cao Zhengzheng, Guo Fangxu, Rong Tao et al. · 2026 · Scientific Reports
Floor aquifers are responsible for approximately 55% of water inrush incidents in coal mines. As mining depths increase, the risk posed by confined floor aquifers becomes more severe. Grouting reinforcement and the sealing of water…
View details →Xiaohua Xiao, Xueqin Yan, Chunhua Liang et al. · 2026 · Frontiers in Neurology
Alzheimer's disease (AD) is a gradual and irreversible decline in the brain's ability to function which is not only signified by amyloid-beta plaques and neurofibrillary tangles but also by and metabolic and mitochondrial changes that have a negative impact on the classical neuropathological hallmarks. It is becoming increasingly clear that the central roles in the process of synaptic dysfunction, neuronal death and cognitive decline are played by the brain's impaired glucose utilization, insulin resistance, lipid metabolism alterations, and energy homeostasis disruption. Mitochondrial dysfunc
View details →Lambodhar Damodaran, Anna S. Jaeger, Louise H. Moncla · 2025 · Nature
Abstract Since late 2021, a panzootic of highly pathogenic H5N1 has devastated wild birds, agriculture and mammals. Here an analysis of 1,818 haemagglutinin sequences from wild birds, domestic birds and mammals reveals that the North American panzootic was driven by around nine introductions into the Atlantic and Pacific flyways, followed by rapid dissemination through wild, migratory birds. Transmission was primarily driven by Anseriformes, while non-canonical species acted as dead-end hosts. In contrast to the epizootic of 2015 (refs. 1,2 ), outbreaks in domestic birds were driven by around
View details →Lucia Chico, Erika Schirinzi, Linda Balestrini et al. · 2026 · International Journal of Molecular Sciences
Neurodegenerative diseases (NDs) are among the leading causes of disability and mortality worldwide and are characterized by multifactorial pathogenesis involving interconnected mechanisms, such as oxidative stress, protein misfolding and aggregation, neuroinflammation, and mitochondrial dysfunction. Dysregulation of transcription factors, governing cellular defense responses, particularly nuclear factor erythroid 2-related factor 2 (Nrf2), a key regulator of antioxidant and proteostatic pathways, plays a critical role in neurodegenerative processes. Currently, available pharmacological treatm
View details →Moritz Mager, Lukas Zeilerbauer, Alexander Felgel-Farnholz et al. · 2026 · Waste Management
European legislation, particularly the Packaging and Packaging Waste Regulation (PPWR), is rapidly increasing the demand for high-quality recycled polypropylene (PP) in packaging applications. Achieving such qualities through mechanical recycling remains challenging due to the heterogeneity of post-consumer waste, while the role of intensified washing in the overall decontamination remains debated. This study evaluates the influence of additional sorting and washing intensity on material properties, product performance, and environmental impacts in mechanical recycling of Dutch post-consumer r
View details →Sathish Babu Vasamsetti, Samreen Sadaf, Mohammad A. Uddin et al. · 2026 · Nature Communications
How cellular metabolism facilitates tissue-resident macrophage maintenance remains elusive. Here we show that visceral adipose tissue (VAT)-resident macrophages, unlike monocyte-derived macrophages, are enriched with mitochondrial-specific antioxidant enzymes restraining inflammation and promoting VAT homeostasis and insulin sensitivity. Additionally, VAT resident macrophages express high levels of plasminogen activator inhibitor type 2, encoded by SerpinB2, which is involved in the blood coagulation cascade. SerpinB2 promotes adipose resident macrophage survival by regulating mitochondrial ox
View details →Ryan J. Farrell, S. Thomas Hennigan, Kirsten G. Bredvik et al. · 2026 · The Journal of General Physiology
The ER is an important regulator of Ca2+ in cells and dysregulation of ER Ca2+ homeostasis can lead to numerous pathologies. Understanding how various pharmacological and genetic perturbations of ER Ca2+ homeostasis impact cellular…
View details →L E Mayorga, Arnau Noguera Segura, Laura Campderros et al. · 2026 · Gut
BACKGROUND: Inflammatory bowel disease (IBD) arises from complex interactions among diet, host and gut microbiome. Although diet influences intestinal inflammation, the microbial and metabolic pathways involved, and their differences…
View details →Byong Duk Ye, Hyo Jong Kim, Dongil Park et al. · 2026 · Journal of Gastroenterology and Hepatology
BACKGROUND AND AIM: The incidence of ulcerative colitis (UC) has been increasing in Asia. Comprehensive data on the long-term course of moderate-to-severe UC remain scarce. This study investigated the clinical outcomes and factors…
View details →Sterling Williams-Ceci, Maurice Jakesch, Advait Bhat et al. · 2026 · Science Advances
Artificial intelligence (AI) writing assistants powered by large language models (LLMs) are increasingly used to make autocomplete suggestions to people as they write text. Can these AI writing assistants affect people’s attitudes in this…
View details →Elena Krugliakova, Friederike Breuer, Nico Adelhöfer et al. · 2025 · Physiological Reviews
Sleep is essentially contributing to human health and well-being through multiple biological functions, including restoration and biosynthesis, brain clearance, energy metabolism, immunological and endocrine processing, synaptic…
View details →Joaquin A. Anguera, Aleem Choudhry, Michael Seaman et al. · 2025 · JMIR Formative Research
Background There is evidence that cognitive training interventions can positively impact executive functions, and that some studies have demonstrated that athletes typically exhibit greater accuracy and faster response times on select cognitive tasks. While the engagement of executive functions is suggested to be part of high-level sporting activities, it is unclear whether such training approaches could directly benefit athletic performance. Objective The objective of this study was to evaluate the impact of a combined virtual reality (VR)– and tablet-based cognitive training intervention on
View details →Ghassan M. Khairallah, Samar Al‐Hajj, Hani O. Mowafi et al. · 2025 · BMC Public Health
BACKGROUND: Healthcare workers (HCWs) are exposed to a multitude of hazards in the hospital environment, increasing their risks of sustaining injuries at a higher rate compared to workers in other sectors and resulting in substantial level…
View details →Alessia Paganelli, Federica Papaccio, Mauro Picardo et al. · 2025 · Frontiers in Pharmacology
Vitiligo is a chronic autoimmune condition characterized by the destruction of melanocytes, leading to patchy loss of skin depigmentation. Although its precise cause remains unclear, recent evidence suggests that metabolic disturbances, particularly oxidative stress and mitochondrial dysfunction, may play a significant role in the pathogenesis of the disease. Oxidative stress is thought to damage melanocytes and trigger inflammatory responses, culminating in melanocyte immune-mediate destruction. Additionally, patients with vitiligo often exhibit extra-cutaneous metabolic abnormalities such as
View details →Ashley Lu, Wei-Ting Chen, Maria Dalby et al. · 2026 · Nature Medicine
Alzheimer's disease (AD) is not an inevitable outcome of pathology but a dynamic process shaped by how brain cells respond to amyloid-β (Aβ) and tau. To disentangle these responses, we combined spatial transcriptomics and single-nucleus RNA sequencing of the superior frontal cortex from octogenarians living with or without dementia and from cognitively intact centenarians with comparable Aβ accumulation. We identified six distinct tissue domains representing a spatial pathological continuum of AD, with a key inflection point marked by a shift from Aβ-associated inflammatory changes to tau-asso
View details →Ezequiel Mauro, Tiago de Castro, Marcus Zeitlhoefler et al. · 2025 · Journal of Hepatology
BACKGROUND & AIMS: Non-proportional hazards (NPH) can lead to discrepancies between interim (IA) and final analyses (FA) in randomized controlled trials (RCTs) of hepatocellular carcinoma (HCC). We assessed the impact of NPH in pivotal HCC…
View details →Matěj Opatrný, Tomáš Havránek, Zuzana Iršová et al. · 2025 · Journal of Labor Economics
Class size reduction mandates are frequent and invariably justified by studies reporting positive effects on student achievement. Yet other studies report no effects, and the literature as a whole awaits correction for potential…
View details →Adna Hrapović, Nadia Islam, Asmaa Al Bourghli et al. · 2026 · PeerJ
The growing global demand for effective and safe therapeutics has accelerated advances in biomaterials for drug delivery applications. Biomaterials, including polymers, metals, ceramics, and composites, play a central role in modern medical devices and therapeutic systems by enabling controlled interactions with biological environments. Initially defined as inert materials interfacing with biological systems, biomaterials are now rationally engineered to treat, replace, or evaluate tissue and organ functions. Recent progress in regenerative medicine, nanotechnology, and precision healthcare ha
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